Page last updated: 2024-11-08

triiodothyronine and Hashimoto Disease

triiodothyronine has been researched along with Hashimoto Disease in 70 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Hashimoto Disease: Chronic autoimmune thyroiditis, characterized by the presence of high serum thyroid AUTOANTIBODIES; GOITER; and HYPOTHYROIDISM.

Research Excerpts

ExcerptRelevanceReference
"The protective effects and potential mechanisms of dioscin for autoimmune thyroiditis were explored in a rat model of thyroglobulin-induced autoimmune thyroiditis."8.31Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling. ( Liu, T; Qin, L; Wu, L; Yan, Z; Zhang, C; Zhang, Q, 2023)
"Low free triiodothyronine (FT3) is usually associated with worse functional outcome in critical illness; however, the information on thyroid dysfunction and autoimmune encephalitis (AE) is limited."8.12Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis. ( Jiang, J; Liu, XW; Qiao, S; Wang, AH; Wang, L; Wang, ZH; Zhang, RR; Zhang, SC, 2022)
"To investigate the potential association between serum inflammatory cytokine levels and thyroxine replacement dose in patients with Hashimoto disease."7.73Thyroxine replacement dose in patients with Hashimoto disease: a potential role for interleukin-6. ( Antonoglou, C; Kotsiou, S; Maltezos, E; Papanas, N; Papatheodorou, K; Papazoglou, D, 2006)
"Myxedema coma is a rare endocrine emergency resulting from the decompensation of severe hypothyroidism, which is associated with a high mortality rate."5.51Successful treatment of myxedema coma with a combination of levothyroxine and liothyronine. ( Kiyota, A; Okazaki, M; Ozaki, N; Tsuchida, M; Ueda, K, 2019)
" During pregnancy, mildly elevated maternal free thyroxine levels less than 20% above the upper limit may not be harmful to unaffected fetuses."4.98Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature. ( Guan, H; Guo, H; Guo, R; Li, Y; Shan, Z; Wu, D, 2018)
"The protective effects and potential mechanisms of dioscin for autoimmune thyroiditis were explored in a rat model of thyroglobulin-induced autoimmune thyroiditis."4.31Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling. ( Liu, T; Qin, L; Wu, L; Yan, Z; Zhang, C; Zhang, Q, 2023)
"Low free triiodothyronine (FT3) is usually associated with worse functional outcome in critical illness; however, the information on thyroid dysfunction and autoimmune encephalitis (AE) is limited."4.12Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis. ( Jiang, J; Liu, XW; Qiao, S; Wang, AH; Wang, L; Wang, ZH; Zhang, RR; Zhang, SC, 2022)
" There is insufficient evidence to recommend for or against therapy with triiodothyronine (T3), apart from in pregnancy when only levothyroxine is indicated, as T3 does not sufficiently cross fetal blood‑brain barrier."4.12Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment. ( Klubo-Gwiezdzinska, J; Wartofsky, L, 2022)
" A diagnosis of autoimmune thyroiditis (AT) in thyrotoxic phase was made on the basis of clinical presentation and presence of anti-TPO antibodies and reduced uptake in thyroid (technetium) scintigraphy."3.91Auto-immune Thyroiditis in an Infant Masquerading as Congenital Nephrotic Syndrome. ( Bavdekar, SB; Jondhale, SN; Koppikar, RG; Save, SU, 2019)
" We assessed the subjects according to the Simplified Menopause Index, menstrual status, thyroid hormone measurements (thyroid stimulating hormone, free thyroxine, free triiodothyronine), the presence of Hashimoto's disease antibodies (anti-thyroid peroxidase antibody or anti-thyroglobulin antibody), the presence of Grave's disease (anti-TSH receptor antibody), markers of thyroid tumor (high thyroglobulin), and thyroid ultrasonography studies."3.79Comparison of the symptoms of menopause and symptoms of thyroid disease in Japanese women aged 35-59 years. ( Ohi, K; Oi, N, 2013)
"The present study was designed to investigate the relationship between the serum levels of oxidant-antioxidant system (malondialdehyde (MDA) level, Paraoxonase (PON1) activity, nitric oxide (NO) level and superoxide dismutase (SOD) activity) and thyroid hormone status in hypothyroidism pre and posttreatment."3.74Oxidative stress and enzymatic antioxidant status in patients with hypothyroidism before and after treatment. ( Atmaca, H; Baskol, G; Baskol, M; Bayram, F; Kocer, D; Tanriverdi, F, 2007)
"Four patients with chronic hypothyroidism who were placed on metformin participated in the study."3.73Thyrotropin suppression by metformin. ( Filmore-Nassar, A; Glass, AR; Vigersky, RA, 2006)
"To investigate the potential association between serum inflammatory cytokine levels and thyroxine replacement dose in patients with Hashimoto disease."3.73Thyroxine replacement dose in patients with Hashimoto disease: a potential role for interleukin-6. ( Antonoglou, C; Kotsiou, S; Maltezos, E; Papanas, N; Papatheodorou, K; Papazoglou, D, 2006)
"Hashimoto disease is a chronic autoimmune thyroiditis."2.90Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial. ( Bernklev, T; Carlsen, E; Gibbs, C; Guldvog, I; Hoff, G; Johnsen, L; Kvaløy, JT; Lauzike, A; Lende, TH; Narvestad, JK; Omdal, R; Reitsma, LC; Søiland, H, 2019)
"Our data demonstrated that in Hashimoto thyroiditis, patients have high levels of TAFI activity compared to controls."2.74The effect of hormone replacement treatment on thrombin-activatable fibrinolysis inhibitor activity levels in patients with Hashimoto thyroiditis. ( Buyukkeçeci, F; Cetinkalp, S; Karadeniz, M; Tobu, M; Yilmaz, C, 2009)
"Dysbiosis has not only been found in AITDs, but has also been reported in thyroid carcinoma, in which an increased number of carcinogenic and inflammatory bacterial strains were observed."2.66Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function? ( Amrein, K; Knezevic, J; Starchl, C; Tmava Berisha, A, 2020)
"Triiodothyronine (T3) is a key regulator of bone, muscle and articular cartilage."2.58[Osteoarthropathies and Myopathies associated with Disorders of the Thyroid Endocrine System]. ( Nehls, V, 2018)
"Those with Hashimoto's disease and very high anti-thyroid peroxidase (anti-TPO) thyroid antibody levels may benefit from total thyroidectomy."1.72More trials for the unhappy hypothyroid patient on thyroxine: a clinician's perspective. ( Welborn, TA, 2022)
"Papillary thyroid cancer (80% of thyroid cancer) whose incidence is increasing worldwide, is associated with Hashimoto's thyroiditis."1.51A model of the cost of delaying treatment of Hashimotos thyroiditis: thyroid cancer initiation and growth. ( Merrill, SJ; Pandiyan, B, 2019)
"Myxedema coma is a rare endocrine emergency resulting from the decompensation of severe hypothyroidism, which is associated with a high mortality rate."1.51Successful treatment of myxedema coma with a combination of levothyroxine and liothyronine. ( Kiyota, A; Okazaki, M; Ozaki, N; Tsuchida, M; Ueda, K, 2019)
" The peak T3 concentration after dosing of liothyronine during week 6 was 292."1.43Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters. ( Burman, KD; Jonklaas, J, 2016)
"Benign breast diseases were detected in 54."1.42The prevalence of benign breast diseases in patients with nodular goiter and Hashimoto's thyroiditis. ( Anil, C; Guney, T; Gursoy, A, 2015)
"Twenty patients with Graves' disease, 21 patients with Hashimoto hypothyroidism, 21 euthyroid Hashimoto patients, and 27 control subjects were recruited to this study."1.39Increased serum interleukin-33 levels in patients with Graves' disease. ( Abusoglu, S; Avcikucuk, M; Burnik, SF; Celik, HT; Ceylan, B; Ercan, M; Serdar, MA; Sezer, S; Uguz, N; Yildirimkaya, M, 2013)
"The prevalence of Hashimoto thyroiditis and NHLT in the 560 papillary thyroid cancer (PTC) patients was found to be 7."1.38Diagnostic value of antithyroid peroxidase antibody for incidental autoimmune thyroiditis based on histopathologic results. ( Hong, HP; Jung, SJ; Kang, T; Kim, DW; Kim, YW; Kwon, MJ; Park, YM; Rho, MH, 2012)
"Myxedema coma (MC) is a rare, but often fatal endocrine emergency."1.37A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis. ( Chihara, K; Hino, Y; Iida, K; Ohara, T, 2011)
"To evaluate the prevalence of chronic autoimmune thyroiditis or Hashimoto's thyroiditis (HT) in a group of patients with spondyloarthritis (SpA)."1.37Prevalence of thyroid autoimmunity in patients with spondyloarthropathies. ( Bruner, V; Del Puente, A; Di Minno, MN; Foglia, F; Iervolino, S; Lupoli, G; Lupoli, GA; Lupoli, R; Peluso, R; Scarpa, R, 2011)
"The development of Graves' disease (GD) from Hashimoto's thyroiditis (HT) has sporadically been reported, but no data are available concerning the prevalence of this sequence of events in GD patients."1.36Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease. ( Arrigo, T; Corrias, A; De Luca, F; Lombardo, F; Mussa, A; Salerno, M; Vigone, MC; Wasniewska, M, 2010)
"These results indicated that Graves' disease (GD) caused primary hyperthyroidism."1.36Clinical features of primary hyperthyroidism caused by Graves' disease admixed with resistance to thyroid hormone (P453T). ( Sato, H, 2010)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.43)18.7374
1990's0 (0.00)18.2507
2000's14 (20.00)29.6817
2010's42 (60.00)24.3611
2020's13 (18.57)2.80

Authors

AuthorsStudies
Weng, L1
Huang, G1
Gong, L3
Xu, J4
Mao, Y1
Li, Y5
Li, M3
Qiao, S1
Zhang, SC1
Zhang, RR1
Wang, L1
Wang, ZH1
Jiang, J1
Wang, AH1
Liu, XW1
Cai, Y1
Wang, Z1
Liu, X1
Wei, L1
Li, S1
Zheng, X1
Yang, T1
Xu, X1
Klubo-Gwiezdzinska, J1
Wartofsky, L1
Welborn, TA1
Dijck-Brouwer, DAJ1
Muskiet, FAJ1
Verheesen, RH1
Schaafsma, G1
Schaafsma, A1
Geurts, JMW1
Shi, S2
Zhou, Y2
Zhang, C1
Zhang, Q1
Qin, L1
Yan, Z1
Wu, L1
Liu, T1
Kiziltoprak, H1
Koc, M1
Tekin, K1
Hekimoglu, R1
Inanc, M1
Yılmaz, AA1
Elmaoğulları, S1
Aycan, Z1
Liu, J1
Fu, J1
Jia, Y1
Yang, N1
Li, J1
Wang, G1
Pandiyan, B2
Merrill, SJ2
Knezevic, J1
Starchl, C1
Tmava Berisha, A1
Amrein, K1
Kaličanin, D1
Brčić, L1
Ljubetić, K1
Barić, A1
Gračan, S1
Brekalo, M1
Torlak Lovrić, V1
Kolčić, I1
Polašek, O1
Zemunik, T1
Punda, A1
Boraska Perica, V1
Pace, C1
Tumino, D1
Russo, M1
Le Moli, R1
Naselli, A1
Borzì, G1
Malandrino, P1
Frasca, F1
Guo, Q1
Wu, D2
Yu, H1
Bao, J1
Peng, S1
Shan, Z2
Guan, H2
Teng, W1
Ruggeri, RM2
Cristani, M1
Vicchio, TM1
Alibrandi, A1
Giovinazzo, S1
Saija, A1
Campennì, A2
Trimarchi, F2
Gangemi, S1
Nehls, V1
Jondhale, SN1
Save, SU1
Koppikar, RG1
Bavdekar, SB1
Bladowska, J1
Waliszewska-Prosół, M1
Ejma, M1
Sąsiadek, M1
Ahmad, S1
Giannopoulou, A1
Owen, P1
Kalhan, A1
Guo, R1
Guo, H2
Gonzalez-Aguilera, B1
Betea, D1
Lutteri, L1
Cavalier, E1
Geenen, V1
Beckers, A1
Valdes-Socin, H1
Ueda, K1
Kiyota, A1
Tsuchida, M1
Okazaki, M1
Ozaki, N1
Guldvog, I1
Reitsma, LC1
Johnsen, L1
Lauzike, A1
Gibbs, C1
Carlsen, E1
Lende, TH1
Narvestad, JK1
Omdal, R1
Kvaløy, JT1
Hoff, G1
Bernklev, T1
Søiland, H1
Benvenga, S2
Celik, HT1
Abusoglu, S1
Burnik, SF1
Sezer, S1
Serdar, MA1
Ercan, M1
Uguz, N1
Avcikucuk, M1
Ceylan, B1
Yildirimkaya, M1
Di Crescenzo, V1
D'Antonio, A1
Tonacchera, M1
Carlomagno, C1
Vitale, M1
Sawicka-Gutaj, N2
Gutaj, P2
Sowiński, J2
Wender-Ożegowska, E1
Czarnywojtek, A1
Brązert, J1
Ruchała, M2
Lee, HS1
Hwang, JS1
Yoshihara, A1
Noh, JY1
Mukasa, K1
Suzuki, M1
Ohye, H1
Matsumoto, M1
Kunii, Y1
Watanabe, N1
Suzuki, N1
Kameda, T1
Sugino, K1
Ito, K1
Anil, C1
Guney, T1
Gursoy, A2
Jonklaas, J1
Burman, KD1
Mizutani, Y1
Ito, M1
Takahashi, T1
Seishima, M1
Salerno, M3
Capalbo, D1
Cerbone, M1
De Luca, F2
Chen, DN1
Cui, J1
Xin, Z1
Yang, GR1
Niu, MJ1
Yang, JK1
Lee, MN1
Lee, SY1
Hur, KY1
Park, HD1
Kiguradze, T1
Bruins, FM1
Guido, N1
Bhattacharya, T1
Rademaker, A1
Florek, AG1
Posligua, A1
Amin, S1
Laumann, AE1
West, DP1
Nardone, B1
Schmidt, M1
Voell, M1
Rahlff, I1
Dietlein, M1
Kobe, C1
Faust, M1
Schicha, H1
Radetti, G2
Kleon, W1
Buzi, F2
Crivellaro, C1
Pappalardo, L1
di Iorgi, N1
Maghnie, M1
Scagliusi, P1
Sisto, M1
Lisi, S1
Lazzari, A1
D'Amore, M1
Koga, M1
Murai, J1
Saito, H1
Matsumoto, S1
Kasayama, S1
Cetinkalp, S1
Tobu, M1
Karadeniz, M1
Buyukkeçeci, F1
Yilmaz, C1
Biondi, B2
Galderisi, M1
Pagano, L1
Sidiropulos, M1
Pulcrano, M1
D' Errico, A1
Ippolito, S1
Rossi, A1
de Divitiis, O1
Lombardi, G1
Sahin, M1
Sade, LE1
Tutuncu, NB1
Kebapcilar, L1
Kabapcilar, L1
Muderrisoglu, H1
Guvener, ND1
Akcakoyun, M1
Emiroglu, Y1
Pala, S1
Kargin, R1
Guler, GB1
Esen, O1
Karapinar, H1
Say, B1
Esen, AM1
Potlukova, E1
Jiskra, J1
Freiberger, T1
Limanova, Z1
Zivorova, D1
Malickova, K1
Springer, D1
Grodecka, L1
Antosova, M1
Telicka, Z1
Pesickova, SS1
Trendelenburg, M1
Wasniewska, M1
Corrias, A2
Arrigo, T1
Lombardo, F1
Mussa, A2
Vigone, MC1
Sato, H1
Sawicka, B1
Bossowski, A1
Szalecki, M1
Wysoka, J1
Koput, A1
Zelazowska-Rutkowska, B1
Tobolczyk, J1
Rogowski, F1
Łuba, M1
Iida, K1
Hino, Y1
Ohara, T1
Chihara, K1
Mao, C1
Wang, S2
Xiao, Y1
Jiang, Q1
Jin, M1
Jiang, X1
Ning, G1
Zhang, Y1
Srivastava, B1
Gelson, W1
Griffiths, A1
Peluso, R1
Lupoli, GA2
Del Puente, A1
Iervolino, S1
Bruner, V1
Lupoli, R1
Di Minno, MN1
Foglia, F1
Scarpa, R1
Lupoli, G1
Maselli, M1
Cambiaso, P1
Cappa, M1
Baiocchi, M1
Gastaldi, R1
Minerba, L1
Loche, S1
Sindoni, A1
Baldari, S1
Rho, MH1
Kim, DW1
Hong, HP1
Park, YM1
Kwon, MJ1
Jung, SJ1
Kim, YW1
Kang, T1
Lo Muzio, L1
Santarelli, A1
Campisi, G1
Lacaita, M1
Favia, G1
Balázs, C1
Türke, B1
Vámos, A1
Öztürk, Ü1
Vural, P1
Özderya, A1
Karadağ, B1
Doğru-Abbasoğlu, S1
Uysal, M1
Oi, N1
Ohi, K1
Baidoo, SE1
Liu, Y1
Zhu, C1
Tian, J1
Ma, J1
Tong, J1
Chen, J1
Tang, X1
Xu, H1
Lu, L1
SKILLERN, PG1
Vigersky, RA1
Filmore-Nassar, A1
Glass, AR1
Xiang, GD1
He, YS1
Zhao, LS1
Hou, J1
Yue, L1
Xiang, HJ1
Zeppa, P1
Marino, G1
Lepore, M1
Troncone, G1
Picardi, M1
Pane, F1
Vetrani, A1
Palombini, L1
Ito, C1
Watanabe, M2
Okuda, N1
Watanabe, C1
Iwatani, Y2
Papanas, N1
Papazoglou, D1
Papatheodorou, K1
Antonoglou, C1
Kotsiou, S1
Maltezos, E1
Baskol, G1
Atmaca, H1
Tanriverdi, F1
Baskol, M1
Kocer, D1
Bayram, F1
Santoh, T1
Kuroda, S1
Ueda, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Surgical Treatment of Hashimotos Disease. Effect on Antibodies and Clinical Symptoms.[NCT02319538]150 participants (Actual)Interventional2012-02-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for triiodothyronine and Hashimoto Disease

ArticleYear
Thyroidal and Extrathyroidal Requirements for Iodine and Selenium: A Combined Evolutionary and (Patho)Physiological Approach.
    Nutrients, 2022, Sep-20, Volume: 14, Issue:19

    Topics: Antioxidants; Hashimoto Disease; Humans; Hydrogen Peroxide; Iodides; Iodine; Male; Oxidants; Peroxid

2022
Thyroid-Gut-Axis: How Does the Microbiota Influence Thyroid Function?
    Nutrients, 2020, Jun-12, Volume: 12, Issue:6

    Topics: Bariatric Surgery; Celiac Disease; Dysbiosis; Female; Gastrointestinal Microbiome; Graves Disease; H

2020
[Osteoarthropathies and Myopathies associated with Disorders of the Thyroid Endocrine System].
    Deutsche medizinische Wochenschrift (1946), 2018, Volume: 143, Issue:16

    Topics: Cartilage, Articular; Fibromyalgia; Hashimoto Disease; Humans; Hyperthyroidism; Hypothyroidism; Iodi

2018
Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature.
    BMC pregnancy and childbirth, 2018, Dec-03, Volume: 18, Issue:1

    Topics: Adult; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Humans; Hypothyroidism; Mutation; Postp

2018
Influence of cigarette smoking on thyroid gland--an update.
    Endokrynologia Polska, 2014, Volume: 65, Issue:1

    Topics: Female; Graves Disease; Hashimoto Disease; Humans; Hyperthyroidism; Hypothyroidism; Pregnancy; Pregn

2014
Subclinical hypothyroidism in childhood - current knowledge and open issues.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:12

    Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic;

2016

Trials

3 trials available for triiodothyronine and Hashimoto Disease

ArticleYear
Local Ocular Surface Alterations in Children with Hashimoto's Thyroiditis.
    Ocular immunology and inflammation, 2020, Jul-03, Volume: 28, Issue:5

    Topics: Adolescent; Autoantibodies; Cell Count; Child; Conjunctiva; Cross-Sectional Studies; Dry Eye Syndrom

2020
Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial.
    Annals of internal medicine, 2019, 04-02, Volume: 170, Issue:7

    Topics: Adolescent; Adult; Aged; Antibodies; Drug Therapy, Combination; Fatigue; Female; Follow-Up Studies;

2019
The effect of hormone replacement treatment on thrombin-activatable fibrinolysis inhibitor activity levels in patients with Hashimoto thyroiditis.
    Internal medicine (Tokyo, Japan), 2009, Volume: 48, Issue:5

    Topics: Adolescent; Adult; Aged; Blood Pressure; Carboxypeptidase B2; Female; Fibrinolysis; Hashimoto Diseas

2009

Other Studies

61 other studies available for triiodothyronine and Hashimoto Disease

ArticleYear
Low levels of serum IL-39 are associated with autoimmune thyroid disease.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:4

    Topics: Case-Control Studies; Graves Disease; Hashimoto Disease; Humans; Interleukins; Triiodothyronine

2022
Thyroid Function and Low Free Triiodothyronine in Chinese Patients With Autoimmune Encephalitis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: China; Encephalitis; Hashimoto Disease; Humans; Male; Retrospective Studies; Thyroid Gland; Thyroxin

2022
The Frequency of Intrathyroidal Follicular Helper T Cells Varies with the Progression of Graves' Disease and Hashimoto's Thyroiditis.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Adult; Autoantibodies; Biomarkers; Disease Progression; Female; Graves Disease; Hashimoto Disease; H

2022
Hashimoto thyroiditis: an evidence-based guide to etiology, diagnosis and treatment.
    Polish archives of internal medicine, 2022, 03-30, Volume: 132, Issue:3

    Topics: Female; Hashimoto Disease; Humans; Hypothyroidism; Infant, Newborn; Male; Pregnancy; Premature Birth

2022
More trials for the unhappy hypothyroid patient on thyroxine: a clinician's perspective.
    Trends in endocrinology and metabolism: TEM, 2022, Volume: 33, Issue:8

    Topics: Hashimoto Disease; Humans; Hypothyroidism; Thyroxine; Triiodothyronine

2022
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis.
    Clinical biochemistry, 2023, Volume: 112

    Topics: Clinical Relevance; Hashimoto Disease; Humans; Interleukins; Thyrotropin; Triiodothyronine

2023
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis.
    Clinical biochemistry, 2023, Volume: 112

    Topics: Clinical Relevance; Hashimoto Disease; Humans; Interleukins; Thyrotropin; Triiodothyronine

2023
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis.
    Clinical biochemistry, 2023, Volume: 112

    Topics: Clinical Relevance; Hashimoto Disease; Humans; Interleukins; Thyrotropin; Triiodothyronine

2023
Clinical significance of elevated serum IL-36γ levels in patients with early-stage Hashimoto's thyroiditis.
    Clinical biochemistry, 2023, Volume: 112

    Topics: Clinical Relevance; Hashimoto Disease; Humans; Interleukins; Thyrotropin; Triiodothyronine

2023
Dioscin Ameliorates Experimental Autoimmune Thyroiditis via the mTOR and TLR4/NF-κB Signaling.
    Drug design, development and therapy, 2023, Volume: 17

    Topics: Animals; Autoantibodies; Hashimoto Disease; NF-kappa B; Rats; Thyroglobulin; Thyroiditis, Autoimmune

2023
SERUM METABOLOMIC PATTERNS IN PATIENTS WITH AUTOIMMUNE THYROID DISEASE.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2020, Volume: 26, Issue:1

    Topics: Hashimoto Disease; Humans; Hypothyroidism; Metabolomics; Thyroid Diseases; Thyrotropin; Thyroxine; T

2020
A model of the cost of delaying treatment of Hashimotos thyroiditis: thyroid cancer initiation and growth.
    Mathematical biosciences and engineering : MBE, 2019, 09-05, Volume: 16, Issue:6

    Topics: Biopsy, Fine-Needle; Computer Simulation; Disease Progression; Hashimoto Disease; Humans; Hypothalam

2019
Differences in food consumption between patients with Hashimoto's thyroiditis and healthy individuals.
    Scientific reports, 2020, 06-30, Volume: 10, Issue:1

    Topics: Adult; Blood Pressure; Case-Control Studies; Diet; Female; Hashimoto Disease; Humans; Male; Middle A

2020
Role of selenium and myo-inositol supplementation on autoimmune thyroiditis progression.
    Endocrine journal, 2020, Nov-28, Volume: 67, Issue:11

    Topics: Adult; Autoantibodies; Disease Progression; Drug Therapy, Combination; Female; Hashimoto Disease; Hu

2020
Alterations of Global DNA Methylation and DNA Methyltransferase Expression in T and B Lymphocytes from Patients with Newly Diagnosed Autoimmune Thyroid Diseases After Treatment: A Follow-Up Study.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:3

    Topics: Adult; B-Lymphocytes; Cross-Sectional Studies; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylatio

2018
Increased serum interleukin-37 (IL-37) levels correlate with oxidative stress parameters in Hashimoto's thyroiditis.
    Journal of endocrinological investigation, 2019, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Female; Glycation End Products, Advanced; Hashimoto Disease; Humans;

2019
Auto-immune Thyroiditis in an Infant Masquerading as Congenital Nephrotic Syndrome.
    Indian journal of pediatrics, 2019, Volume: 86, Issue:2

    Topics: Carbimazole; Female; Hashimoto Disease; Humans; Hyperthyroidism; Hypertriglyceridemia; Hypoalbuminem

2019
The metabolic alterations within the normal appearing brain in patients with Hashimoto's thyroiditis are correlated with hormonal changes.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Adult; Aspartic Acid; Brain; Choline; Cognition; Creatine; Female; Hashimoto Disease; Humans; Magnet

2019
Polyglandular endocrine emergency: lessons from a patient, which a book cannot teach.
    BMJ case reports, 2018, Nov-08, Volume: 2018

    Topics: Addison Disease; Adrenergic beta-Agonists; Adult; Anti-Inflammatory Agents; Celiac Disease; Diabetes

2018
Conversion to Graves disease from Hashimoto thyroiditis: a study of 24 patients.
    Archives of endocrinology and metabolism, 2018, Volume: 62, Issue:6

    Topics: Adult; Autoantibodies; Female; Graves Disease; Hashimoto Disease; Humans; Hypothyroidism; Immunoglob

2018
Successful treatment of myxedema coma with a combination of levothyroxine and liothyronine.
    Endocrine journal, 2019, May-28, Volume: 66, Issue:5

    Topics: Aged, 80 and over; Coma; Drug Therapy, Combination; Hashimoto Disease; Humans; Male; Myxedema; Thyro

2019
A patient-specific model of the negative-feedback control of the hypothalamus-pituitary-thyroid (HPT) axis in autoimmune (Hashimoto's) thyroiditis.
    Mathematical medicine and biology : a journal of the IMA, 2014, Volume: 31, Issue:3

    Topics: Computer Simulation; Feedback; Hashimoto Disease; Humans; Hypothalamus; Iodide Peroxidase; Models, I

2014
Increased serum interleukin-33 levels in patients with Graves' disease.
    Endocrine regulations, 2013, Volume: 47, Issue:2

    Topics: Adult; Aged; Autoimmunity; Biomarkers; Female; Graves Disease; Hashimoto Disease; Humans; Interferon

2013
Human herpes virus associated with Hashimoto's thyroiditis.
    Le infezioni in medicina, 2013, Volume: 21, Issue:3

    Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Herpes Labialis; Humans; Im

2013
The natural course of Hashimoto's thyroiditis in children and adolescents.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:9-10

    Topics: Adolescent; Child; Disease Progression; Female; Hashimoto Disease; Humans; Hypothyroidism; Male; Ret

2014
The role of free triiodothyronine in pathogenesis of infertility in levothyroxine-treated women with thyroid autoimmunity - a preliminary observational study.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:2

    Topics: Adult; Case-Control Studies; Female; Hashimoto Disease; Humans; Infertility, Female; Pilot Projects;

2015
Serum human chorionic gonadotropin levels and thyroid hormone levels in gestational transient thyrotoxicosis: Is the serum hCG level useful for differentiating between active Graves' disease and GTT?
    Endocrine journal, 2015, Volume: 62, Issue:6

    Topics: Algorithms; Chorionic Gonadotropin; Diagnosis, Differential; Female; Graves Disease; Hashimoto Disea

2015
The prevalence of benign breast diseases in patients with nodular goiter and Hashimoto's thyroiditis.
    Journal of endocrinological investigation, 2015, Volume: 38, Issue:9

    Topics: Adult; Autoantibodies; Breast Diseases; Case-Control Studies; Comorbidity; Female; Goiter, Nodular;

2015
Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:6

    Topics: Adult; Drug Administration Schedule; Drug Therapy, Combination; Female; Hashimoto Disease; Hormone R

2016
Acquired palmoplantar keratoderma associated with hypothyroidism.
    The Journal of dermatology, 2016, Volume: 43, Issue:10

    Topics: Administration, Oral; Aged; Female; Hashimoto Disease; Humans; Keratoderma, Palmoplantar; Middle Age

2016
Using Hashimoto thyroiditis as gold standard to determine the upper limit value of thyroid stimulating hormone in a Chinese cohort.
    BMC endocrine disorders, 2016, Nov-06, Volume: 16, Issue:1

    Topics: Adult; Cohort Studies; Female; Hashimoto Disease; Humans; Immunoglobulins, Thyroid-Stimulating; Male

2016
Thyroxine (T4) Autoantibody Interference of Free T4 Concentration Measurement in a Patient With Hashimoto's Thyroiditis.
    Annals of laboratory medicine, 2017, Volume: 37, Issue:2

    Topics: Adult; Autoantibodies; Female; Hashimoto Disease; Humans; Luminescent Measurements; Radioimmunoassay

2017
Evidence for the association of Hashimoto's thyroiditis with psoriasis: a cross-sectional retrospective study.
    International journal of dermatology, 2017, Volume: 56, Issue:5

    Topics: Adult; Aged; Autoantibodies; Comorbidity; Cross-Sectional Studies; Female; Hashimoto Disease; Humans

2017
Long-term follow-up of antithyroid peroxidase antibodies in patients with chronic autoimmune thyroiditis (Hashimoto's thyroiditis) treated with levothyroxine.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Anti-Idiotypic; Dose-Response Relationship, Drug; Female

2008
Thyroid function and structure are affected in childhood obesity.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:12

    Topics: Autoantibodies; Biopsy, Fine-Needle; Body Mass Index; Child; Cohort Studies; Cross-Sectional Studies

2008
Hashimoto's thyroiditis in Melkersson-Rosenthal syndrome patient: casual association or related diseases?
    Panminerva medica, 2008, Volume: 50, Issue:3

    Topics: Autoantibodies; Autoantigens; Drug Therapy, Combination; Edema; Facial Pain; Female; Hashimoto Disea

2008
Effects of thyroid hormone on serum glycated albumin levels: study on non-diabetic subjects.
    Diabetes research and clinical practice, 2009, Volume: 84, Issue:2

    Topics: Aged; Blood Glucose; Female; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Ad

2009
Endothelial-mediated coronary flow reserve in patients with mild thyroid hormone deficiency.
    European journal of endocrinology, 2009, Volume: 161, Issue:2

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Echocardiography, Doppler, Color;

2009
Systolic pulmonary artery pressure and echocardiographic measurements in patients with euthyroid Hashimoto's thyroiditis.
    Journal of endocrinological investigation, 2009, Volume: 32, Issue:6

    Topics: Adult; Autoantibodies; Blood Glucose; Blood Pressure; Cholesterol; Echocardiography; Female; Hashimo

2009
Heart rate recovery and chronotropic incompetence in patients with subclinical hypothyroidism.
    Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:1

    Topics: Adult; Exercise Test; Female; Hashimoto Disease; Heart Rate; Humans; Hypothyroidism; Male; Thyrotrop

2010
The production of mannan-binding lectin is dependent upon thyroid hormones regardless of the genotype: a cohort study of 95 patients with autoimmune thyroid disorders.
    Clinical immunology (Orlando, Fla.), 2010, Volume: 136, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; C-Reactive Protein; Czech Republic; Female; Genotype; Graves Disease

2010
Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease.
    Hormone research in paediatrics, 2010, Volume: 73, Issue:6

    Topics: Adolescent; Autoantibodies; Child; Disease Progression; Female; Graves Disease; Hashimoto Disease; H

2010
Clinical features of primary hyperthyroidism caused by Graves' disease admixed with resistance to thyroid hormone (P453T).
    Endocrine journal, 2010, Volume: 57, Issue:8

    Topics: Adult; Antithyroid Agents; Female; Graves Disease; Hashimoto Disease; Humans; Immunoglobulins, Thyro

2010
Relationship between metabolic parameters and thyroid hormones and the level of gastric peptides in children with autoimmune thyroid diseases.
    Journal of pediatric endocrinology & metabolism : JPEM, 2010, Volume: 23, Issue:4

    Topics: Adolescent; Blood Glucose; Child; Female; Ghrelin; Goiter; Graves Disease; Hashimoto Disease; Humans

2010
A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis.
    Endocrine journal, 2011, Volume: 58, Issue:2

    Topics: Autoantibodies; Carcinoembryonic Antigen; Cardiomegaly; Coma; Female; Hashimoto Disease; Human Growt

2011
Impairment of regulatory capacity of CD4+CD25+ regulatory T cells mediated by dendritic cell polarization and hyperthyroidism in Graves' disease.
    Journal of immunology (Baltimore, Md. : 1950), 2011, Apr-15, Volume: 186, Issue:8

    Topics: Adult; Apoptosis; Dendritic Cells; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Forkhe

2011
A confused patient with raised anti-thyroid antibodies--an unusual case.
    Clinical medicine (London, England), 2010, Volume: 10, Issue:6

    Topics: Aged; Autoantibodies; Brain Diseases; Diagnosis, Differential; Electroencephalography; Encephalitis;

2010
Prevalence of thyroid autoimmunity in patients with spondyloarthropathies.
    The Journal of rheumatology, 2011, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Aged; Antibodies, Anti-Idiotypic; Autoantibodies; Case-Control Studies; Female; H

2011
The natural history of the normal/mild elevated TSH serum levels in children and adolescents with Hashimoto's thyroiditis and isolated hyperthyrotropinaemia: a 3-year follow-up.
    Clinical endocrinology, 2012, Volume: 76, Issue:3

    Topics: Adolescent; Autoantibodies; Child; Female; Follow-Up Studies; Glycoprotein Hormones, alpha Subunit;

2012
Association of autonomously functioning thyroid nodules with Hashimoto's thyroiditis: study on a large series of patients.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2011, Volume: 119, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Cohort Studies; Female; Goiter, Nodula

2011
Diagnostic value of antithyroid peroxidase antibody for incidental autoimmune thyroiditis based on histopathologic results.
    Endocrine, 2012, Volume: 42, Issue:3

    Topics: Adult; Aged; Analysis of Variance; Antibodies; Carcinoma, Papillary, Follicular; Female; Hashimoto D

2012
Possible link between Hashimoto's thyroiditis and oral lichen planus: a novel association found.
    Clinical oral investigations, 2013, Volume: 17, Issue:1

    Topics: Adult; Autoantibodies; Autoantigens; Cross-Sectional Studies; Female; Hashimoto Disease; Humans; Iod

2013
[Determination of serum neopterin levels in patients with autoimmune thyroid diseases].
    Orvosi hetilap, 2012, Jul-22, Volume: 153, Issue:29

    Topics: Adult; Aged; Autoantibodies; Biomarkers; Female; Graves Disease; Hashimoto Disease; Humans; Iodide P

2012
Oxidative stress parameters in serum and low density lipoproteins of Hashimoto's thyroiditis patients with subclinical and overt hypothyroidism.
    International immunopharmacology, 2012, Volume: 14, Issue:4

    Topics: Adult; Antioxidants; Case-Control Studies; Cholesterol, LDL; Female; Hashimoto Disease; Humans; Hypo

2012
Comparison of the symptoms of menopause and symptoms of thyroid disease in Japanese women aged 35-59 years.
    Climacteric : the journal of the International Menopause Society, 2013, Volume: 16, Issue:5

    Topics: Adult; Arrhythmias, Cardiac; Autoantibodies; Diagnosis, Differential; Female; Flushing; Graves Disea

2013
T cell-derived leptin contributes to increased frequency of T helper type 17 cells in female patients with Hashimoto's thyroiditis.
    Clinical and experimental immunology, 2013, Volume: 171, Issue:1

    Topics: Adult; Autoantibodies; CD4-Positive T-Lymphocytes; Female; Hashimoto Disease; Humans; Interleukin-17

2013
TREATMENT OF HASHIMOTO'S DISEASE AND INVASIVE THYROIDITIS.
    Modern treatment, 1964, Volume: 1

    Topics: Biopsy; Cortisone; Diagnosis, Differential; Hashimoto Disease; Humans; Pathology; Thyroid Hormones;

1964
Thyrotropin suppression by metformin.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Interactions; Female; Goiter; Graves D

2006
Impairment of endothelium-dependent arterial dilation in Hashimoto's thyroiditis patients with euthyroidism.
    Clinical endocrinology, 2006, Volume: 64, Issue:6

    Topics: Atherosclerosis; Autoantibodies; Brachial Artery; Case-Control Studies; Cholesterol, LDL; Endotheliu

2006
Flow cytometry phenotypization of thyroidal lymphoid infiltrate and functional status in Hashimoto's thyroiditis.
    Analytical and quantitative cytology and histology, 2006, Volume: 28, Issue:3

    Topics: Adult; Aged; Antigens, CD; B-Lymphocytes; Female; Flow Cytometry; Hashimoto Disease; Humans; Immunog

2006
Association between the severity of Hashimoto's disease and the functional +874A/T polymorphism in the interferon-gamma gene.
    Endocrine journal, 2006, Volume: 53, Issue:4

    Topics: Autoantibodies; DNA; Electrophoresis, Agar Gel; Genotype; Graves Disease; Hashimoto Disease; Humans;

2006
Thyroxine replacement dose in patients with Hashimoto disease: a potential role for interleukin-6.
    Cytokine, 2006, Volume: 35, Issue:3-4

    Topics: Dose-Response Relationship, Drug; Female; Hashimoto Disease; Humans; Inflammation Mediators; Interle

2006
Oxidative stress and enzymatic antioxidant status in patients with hypothyroidism before and after treatment.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2007, Volume: 115, Issue:8

    Topics: Adult; Aged; Antioxidants; Aryldialkylphosphatase; Female; Hashimoto Disease; Humans; Hypothyroidism

2007
Ratio of serum IgG3 to total IgG concentration and goiter size are independent factors in intractability of Graves' disease.
    Endocrine journal, 2007, Volume: 54, Issue:6

    Topics: Adult; Autoantibodies; Female; Graves Disease; Hashimoto Disease; Humans; Immunoglobulin G; Immunogl

2007