triiodothyronine has been researched along with Glioma in 20 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thyroid hormone (triiodothyronine; T3) has been shown to control the expression of beta 1-adrenergic receptors (beta 1-AR) in cardiac myocytes, but not in C6 glioma cells." | 7.69 | Post-transcriptional induction of beta 1-adrenergic receptor by retinoic acid, but not triiodothyronine, in C6 glioma cells expressing thyroid hormone receptors. ( Bernal, J; García-Higuera, I; Iglesias, T; López-Barahona, M; Mayor, F; Muñoz, A; Zaballos, A, 1996) |
| "We have determined the cellular concentration of thyroxine (T4) and triiodothyronine (T3) and the activities of two brain iodothyronine deiodinases, type II (5'-D2) and type III (5-D3), in two types of tissues --tumour (26) and non-tumour (5), derived either from human gliomas with various histological malignancies or from non-tumoural surrounding brain tissue." | 3.72 | The concentration of thyroid hormones and activities of iodothyronine deiodinases are altered in human brain gliomas. ( Bonicki, W; Czernicki, Z; Michalik, R; Nauman, P; Warzecha, A, 2004) |
| "In this study, the effect of thyroid hormone (triiodothyronine, T(3)) on the secretion of mitogenic growth factors in astrocytes and C6 glioma cells was examined." | 3.71 | Thyroid hormone induces cerebellar astrocytes and C6 glioma cells to secrete mitogenic growth factors. ( Alvarez-Silva, M; Moura Neto, V; Trentin, AG, 2001) |
| "Thyroid hormone (triiodothyronine; T3) has been shown to control the expression of beta 1-adrenergic receptors (beta 1-AR) in cardiac myocytes, but not in C6 glioma cells." | 3.69 | Post-transcriptional induction of beta 1-adrenergic receptor by retinoic acid, but not triiodothyronine, in C6 glioma cells expressing thyroid hormone receptors. ( Bernal, J; García-Higuera, I; Iglesias, T; López-Barahona, M; Mayor, F; Muñoz, A; Zaballos, A, 1996) |
| "The uptake of 3,5,3'-triiodothyronine (T3) and thyroxine (T4) was studied in human glioma cells (Hs 683) and compared with that in several other neural cell lines." | 3.68 | Thyroid hormone transport in a human glioma cell line. ( Goncalves, E; Lakshmanan, M; Pontecorvi, A; Robbins, J, 1990) |
| "Glioma is one of the most common types of primary intracranial tumors." | 1.62 | T3 Promotes Glioma Cell Senescence and Apoptosis via THRA and THRB. ( Li, C; Li, J; Li, L; Liu, W; Ma, W; Tang, Z; Zhang, X, 2021) |
| " There was a striking similarity in the dose-response of butyrate for increasing receptor levels and inhibiting histone deacetylation." | 1.27 | Modulation of thyroid hormone nuclear receptors by short-chain fatty acids in glial C6 cells. Role of histone acetylation. ( Aranda, A; Montiel, F; Ortiz-Caro, J; Pascual, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (25.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 7 (35.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, X | 1 |
| Ma, W | 1 |
| Li, J | 1 |
| Li, C | 1 |
| Liu, W | 1 |
| Tang, Z | 1 |
| Li, L | 1 |
| Lin, HY | 1 |
| Sun, M | 1 |
| Tang, HY | 1 |
| Lin, C | 1 |
| Luidens, MK | 1 |
| Mousa, SA | 1 |
| Incerpi, S | 1 |
| Drusano, GL | 1 |
| Davis, FB | 1 |
| Davis, PJ | 1 |
| Wink, MR | 1 |
| Tamajusuku, AS | 1 |
| Braganhol, E | 1 |
| Casali, EA | 1 |
| Barreto-Chaves, ML | 1 |
| Sarkis, JJ | 1 |
| Battastini, AM | 1 |
| Nauman, P | 1 |
| Bonicki, W | 1 |
| Michalik, R | 1 |
| Warzecha, A | 1 |
| Czernicki, Z | 1 |
| van Santen, HM | 1 |
| Thonissen, NM | 1 |
| de Kraker, J | 1 |
| Vulsma, T | 1 |
| Zamoner, A | 1 |
| Funchal, C | 1 |
| Jacques-Silva, MC | 1 |
| Gottfried, C | 1 |
| Barreto Silva, FR | 1 |
| Pessoa-Pureur, R | 1 |
| Tseng, YT | 1 |
| Waschek, JA | 1 |
| Padbury, JF | 1 |
| Suter-Crazzolara, C | 1 |
| Unsicker, K | 1 |
| Puymirat, J | 1 |
| López-Barahona, M | 1 |
| Iglesias, T | 1 |
| García-Higuera, I | 1 |
| Mayor, F | 1 |
| Zaballos, A | 1 |
| Bernal, J | 1 |
| Muñoz, A | 1 |
| Trentin, AG | 2 |
| Alvarez-Silva, M | 2 |
| Dietrich, JB | 1 |
| Zaepfel, M | 1 |
| Kuchler-Bopp, S | 1 |
| Moura Neto, V | 1 |
| Venter, BR | 1 |
| Venter, JC | 1 |
| Kaplan, NO | 1 |
| Iwasa, Y | 1 |
| Aida, K | 1 |
| Yokomori, N | 1 |
| Inoue, M | 1 |
| Onaya, T | 1 |
| Goncalves, E | 1 |
| Lakshmanan, M | 1 |
| Pontecorvi, A | 1 |
| Robbins, J | 1 |
| Walz, MA | 1 |
| Howlett, AC | 1 |
| Yusta, B | 2 |
| Ortiz-Caro, J | 3 |
| Pascual, A | 3 |
| Aranda, A | 3 |
| Montiel, F | 2 |
| Villa, A | 1 |
1 review available for triiodothyronine and Glioma
| Article | Year |
|---|---|
Thyroid hormone regulates protein expression in C6 glioma cells.
Topics: Animals; Glial Fibrillary Acidic Protein; Glioma; Humans; Triiodothyronine | 1998 |
19 other studies available for triiodothyronine and Glioma
| Article | Year |
|---|---|
T3 Promotes Glioma Cell Senescence and Apoptosis via THRA and THRB.
Topics: Apoptosis; Cell Line, Tumor; Cellular Senescence; Gene Silencing; Glioma; Humans; Thyroid Hormone Re | 2021 |
L-Thyroxine vs. 3,5,3'-triiodo-L-thyronine and cell proliferation: activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase.
Topics: Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Glioma; Humans; Hypoxia-I | 2009 |
Thyroid hormone upregulates ecto-5'-nucleotidase/CD73 in C6 rat glioma cells.
Topics: 5'-Nucleotidase; Animals; Cell Line, Tumor; Dactinomycin; Dose-Response Relationship, Drug; Glioma; | 2003 |
The concentration of thyroid hormones and activities of iodothyronine deiodinases are altered in human brain gliomas.
Topics: Adult; Aged; Analysis of Variance; Brain Neoplasms; Female; Glioma; Humans; Iodide Peroxidase; Male; | 2004 |
Changes in thyroid hormone state in children receiving chemotherapy.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Child, Preschool; | 2005 |
Thyroid hormones reorganize the cytoskeleton of glial cells through Gfap phosphorylation and Rhoa-dependent mechanisms.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cytoskeleton; Glial Fibrillar | 2007 |
Functional analysis of the 5' flanking sequence in the ovine beta 1-adrenergic receptor gene.
Topics: Animals; Base Sequence; Cell Line; Chloramphenicol O-Acetyltransferase; Dexamethasone; Gene Expressi | 1995 |
GDNF mRNA levels are induced by FGF-2 in rat C6 glioblastoma cells.
Topics: Animals; Astrocytes; Brain Neoplasms; Cell Division; Colforsin; Dexamethasone; Fibroblast Growth Fac | 1996 |
Thyroid hormone receptors are necessary but not sufficient for transcription.
Topics: Animals; Gene Expression Regulation; Glioma; Muscles; Neuroblastoma; Rats; Receptors, Adrenergic, be | 1996 |
Post-transcriptional induction of beta 1-adrenergic receptor by retinoic acid, but not triiodothyronine, in C6 glioma cells expressing thyroid hormone receptors.
Topics: Animals; Autoradiography; Blotting, Northern; Densitometry; Dihydroalprenolol; Gene Expression Regul | 1996 |
Expression of intercellular adhesion molecule-1 in C6 glioma cells is up-regulated by thyroid hormone.
Topics: Actins; Animals; Blood-Brain Barrier; Cell Division; Dexamethasone; Encephalitis; Gene Expression Re | 2000 |
Thyroid hormone induces cerebellar astrocytes and C6 glioma cells to secrete mitogenic growth factors.
Topics: Animals; Astrocytes; Cell Division; Cells, Cultured; Cerebellum; Culture Media, Conditioned; Fibrobl | 2001 |
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cell Separation; Cells | 1976 |
Transcriptional regulation of ferritin heavy chain messenger RNA expression by thyroid hormone.
Topics: Animals; Cell Line; Ferritins; Gene Expression Regulation; Glioma; Hyperthyroidism; Macromolecular S | 1990 |
Thyroid hormone transport in a human glioma cell line.
Topics: Aminoisobutyric Acids; Antimycin A; Binding, Competitive; Biological Transport; Cadaverine; Cell Mem | 1990 |
Thyroid effects on adenosine 3',5'-monophosphate levels and adenylate cyclase in cultured neuroblastoma cells.
Topics: Adenylyl Cyclases; Alprostadil; Animals; Astrocytoma; Cell Line; Colforsin; Cyclic AMP; Glioma; Guan | 1987 |
Mechanism of L-triiodothyronine (T3) uptake by glial C6 cells: regulation by butyrate.
Topics: Animals; Antimycin A; Azides; Butyrates; Cell Membrane Permeability; Cyanides; Glioma; Rats; Sodium | 1988 |
Identification and characterization of L-triiodothyronine receptors in cells of glial and neuronal origin.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Glioma; Kinetics; Mice; Neuroblastoma; Ne | 1986 |
Modulation of thyroid hormone nuclear receptors by short-chain fatty acids in glial C6 cells. Role of histone acetylation.
Topics: Acetates; Acetic Acid; Acetylation; Animals; Butyrates; Butyric Acid; Cell Compartmentation; Cell Nu | 1986 |