triiodothyronine has been researched along with Genetic Predisposition in 17 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thyrotoxic hypokalemic periodic paralysis (TPP) is characterized by acute attacks of weakness, hypokalemia, and thyrotoxicosis of various etiologies." | 1.36 | Mutations in potassium channel Kir2.6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis. ( Bernstein, HS; Brown, RH; Cheah, JS; da Silva, MR; Donaldson, MR; Fontaine, B; Ho, SC; Jongjaroenprasert, W; Khoo, DH; Kung, AW; Liang, MC; Maciel, RM; Ptácek, LJ; Ryan, DP; Soong, TW, 2010) |
| "HLA alleles of 106 patients with Graves' disease were determined, and the frequency of HLA-B46 was found to be significantly increased." | 1.29 | Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese. ( Inoko, H; Onuma, H; Ota, M; Sugenoya, A, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Romartinez-Alonso, B | 1 |
| Agostini, M | 1 |
| Jones, H | 1 |
| McLellan, J | 1 |
| Sood, DE | 1 |
| Tomkinson, N | 1 |
| Marelli, F | 1 |
| Gentile, I | 1 |
| Visser, WE | 1 |
| Schoenmakers, E | 1 |
| Fairall, L | 1 |
| Privalsky, M | 1 |
| Moran, C | 1 |
| Persani, L | 1 |
| Chatterjee, K | 1 |
| Schwabe, JWR | 1 |
| Nelson, PT | 1 |
| Gal, Z | 1 |
| Wang, WX | 1 |
| Niedowicz, DM | 1 |
| Artiushin, SC | 1 |
| Wycoff, S | 1 |
| Wei, A | 1 |
| Jicha, GA | 1 |
| Fardo, DW | 1 |
| Luo, M | 1 |
| Zhou, XH | 1 |
| Zou, T | 1 |
| Keyim, K | 1 |
| Dong, LM | 1 |
| Vaurs-Barrière, C | 1 |
| Deville, M | 1 |
| Sarret, C | 1 |
| Giraud, G | 1 |
| Des Portes, V | 1 |
| Prats-Viñas, JM | 1 |
| De Michele, G | 1 |
| Dan, B | 1 |
| Brady, AF | 1 |
| Boespflug-Tanguy, O | 1 |
| Touraine, R | 1 |
| Gudmundsson, J | 1 |
| Sulem, P | 1 |
| Gudbjartsson, DF | 1 |
| Jonasson, JG | 1 |
| Sigurdsson, A | 1 |
| Bergthorsson, JT | 1 |
| He, H | 1 |
| Blondal, T | 1 |
| Geller, F | 1 |
| Jakobsdottir, M | 1 |
| Magnusdottir, DN | 1 |
| Matthiasdottir, S | 1 |
| Stacey, SN | 1 |
| Skarphedinsson, OB | 1 |
| Helgadottir, H | 1 |
| Li, W | 1 |
| Nagy, R | 1 |
| Aguillo, E | 1 |
| Faure, E | 1 |
| Prats, E | 1 |
| Saez, B | 1 |
| Martinez, M | 1 |
| Eyjolfsson, GI | 1 |
| Bjornsdottir, US | 1 |
| Holm, H | 1 |
| Kristjansson, K | 1 |
| Frigge, ML | 1 |
| Kristvinsson, H | 1 |
| Gulcher, JR | 1 |
| Jonsson, T | 1 |
| Rafnar, T | 1 |
| Hjartarsson, H | 1 |
| Mayordomo, JI | 1 |
| de la Chapelle, A | 1 |
| Hrafnkelsson, J | 1 |
| Thorsteinsdottir, U | 1 |
| Kong, A | 1 |
| Stefansson, K | 1 |
| Daroszewski, J | 1 |
| Pawlak, E | 1 |
| Karabon, L | 1 |
| Frydecka, I | 1 |
| Jonkisz, A | 1 |
| Slowik, M | 1 |
| Bolanowski, M | 1 |
| Ryan, DP | 1 |
| da Silva, MR | 1 |
| Soong, TW | 1 |
| Fontaine, B | 1 |
| Donaldson, MR | 1 |
| Kung, AW | 1 |
| Jongjaroenprasert, W | 1 |
| Liang, MC | 1 |
| Khoo, DH | 1 |
| Cheah, JS | 1 |
| Ho, SC | 1 |
| Bernstein, HS | 1 |
| Maciel, RM | 1 |
| Brown, RH | 1 |
| Ptácek, LJ | 1 |
| Rooke, JA | 1 |
| Houdijk, JG | 1 |
| McIlvaney, K | 1 |
| Ashworth, CJ | 1 |
| Dwyer, CM | 1 |
| Meulenbelt, I | 2 |
| Bos, SD | 1 |
| Chapman, K | 1 |
| van der Breggen, R | 2 |
| Houwing-Duistermaat, JJ | 2 |
| Kremer, D | 2 |
| Kloppenburg, M | 2 |
| Carr, A | 1 |
| Tsezou, A | 1 |
| González, A | 1 |
| Loughlin, J | 2 |
| Slagboom, PE | 2 |
| Everaert, N | 1 |
| Willemsen, H | 1 |
| Debonne, M | 1 |
| Witters, A | 1 |
| Kamers, B | 1 |
| Darras, VM | 1 |
| de Baerdemaeker, J | 1 |
| Decuypere, E | 3 |
| Bruggeman, V | 2 |
| Zou, S | 1 |
| Sang, Q | 1 |
| Wang, H | 1 |
| Feng, R | 1 |
| Li, Q | 1 |
| Zhao, X | 1 |
| Xing, Q | 1 |
| Jin, L | 1 |
| He, L | 1 |
| Wang, L | 1 |
| FAENZI, C | 1 |
| Shohet, RV | 1 |
| Kisanuki, YY | 1 |
| Zhao, XS | 1 |
| Siddiquee, Z | 1 |
| Franco, F | 1 |
| Yanagisawa, M | 1 |
| Hassanzadeh, M | 2 |
| Gilanpour, H | 1 |
| Charkhkar, S | 1 |
| Buyse, J | 1 |
| De Smit, L | 1 |
| Tona, K | 1 |
| Onagbesan, O | 1 |
| Arckens, L | 1 |
| Min, JL | 1 |
| Bos, S | 1 |
| Riyazi, N | 1 |
| van der Wijk, HJ | 1 |
| Kroon, HM | 1 |
| Nakajima, M | 1 |
| Ikegawa, S | 1 |
| Uitterlinden, AG | 1 |
| van Meurs, JB | 1 |
| van der Deure, WM | 1 |
| Visser, TJ | 1 |
| Seymour, AB | 1 |
| Lakenberg, N | 1 |
| van Duijn, CM | 1 |
| Onuma, H | 1 |
| Ota, M | 1 |
| Sugenoya, A | 1 |
| Inoko, H | 1 |
1 review available for triiodothyronine and Genetic Predisposition
| Article | Year |
|---|---|
Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility.
Topics: Aged; Biological Availability; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Io | 2011 |
1 trial available for triiodothyronine and Genetic Predisposition
| Article | Year |
|---|---|
Differential effects of maternal undernutrition between days 1 and 90 of pregnancy on ewe and lamb performance and lamb parasitism in hill or lowland breeds.
Topics: Animal Nutritional Physiological Phenomena; Animals; Breeding; Female; Genetic Predisposition to Dis | 2010 |
15 other studies available for triiodothyronine and Genetic Predisposition
| Article | Year |
|---|---|
Structure-Guided Approach to Relieving Transcriptional Repression in Resistance to Thyroid Hormone α.
Topics: Animals; Co-Repressor Proteins; Gene Expression; Genetic Predisposition to Disease; Humans; Mutation | 2022 |
TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.
Topics: Aged; Aged, 80 and over; Aging; Brain; Female; Genetic Predisposition to Disease; Humans; Male; Midd | 2019 |
Type II deiodinase polymorphisms and serum thyroid hormone levels in patients with mild cognitive impairment.
Topics: Adult; Cognitive Dysfunction; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; H | 2015 |
Pelizaeus-Merzbacher-Like disease presentation of MCT8 mutated male subjects.
Topics: Brain; Child; Disease Progression; DNA Mutational Analysis; Exons; Family Health; Follow-Up Studies; | 2009 |
Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
Topics: Chromosome Mapping; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; DNA-Binding Proteins; Eu | 2009 |
Soluble CTLA-4 receptor an immunological marker of Graves' disease and severity of ophthalmopathy is associated with CTLA-4 Jo31 and CT60 gene polymorphisms.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Cohort Studies; CTLA-4 Antigen; DNA; Femal | 2009 |
Mutations in potassium channel Kir2.6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis.
Topics: Amino Acid Sequence; Base Sequence; DNA Mutational Analysis; Electrophysiological Phenomena; Genetic | 2010 |
Interaction between ascites susceptibility and CO(2) during the second half of incubation of two broiler lines: the effect on post-hatch development and ascites mortality.
Topics: Animals; Ascites; Carbon Dioxide; Chick Embryo; Chickens; Corticosterone; Female; Genetic Predisposi | 2012 |
Common genetic variation in CYP1B1 is associated with concentrations of T₄, FT₃ and FT₄ in the sera of polycystic ovary syndrome patients.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Estrogens, Catechol; Female; Genetic | 2013 |
[Influence of thyrotropic substances on the appearance and evolution of genetic susceptibility to audiogenic shock].
Topics: Biological Evolution; Genetic Predisposition to Disease; Shock; Thyrotrophs; Triiodothyronine | 1961 |
Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy.
Topics: Aging; Alleles; Animals; Cardiomegaly; Endothelin-1; Female; Gene Deletion; Genetic Predisposition t | 2004 |
Anatomical parameters of cardiopulmonary system in three different lines of chickens: further evidence for involvement in ascites syndrome.
Topics: Aging; Animals; Ascites; Body Weight; Cardiovascular System; Chickens; Genetic Predisposition to Dis | 2005 |
Comparison of three lines of broilers differing in ascites susceptibility or growth rate. 2. Egg weight loss, gas pressures, embryonic heat production, and physiological hormone levels.
Topics: Animals; Ascites; Carbon Dioxide; Chick Embryo; Corticosterone; Genetic Predisposition to Disease; H | 2005 |
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis.
Topics: Female; Genetic Predisposition to Disease; Genome, Human; Humans; Iodide Peroxidase; Iodothyronine D | 2008 |
Association of HLA-DPB1*0501 with early-onset Graves' disease in Japanese.
Topics: Adolescent; Adult; Disease Susceptibility; Female; Genetic Predisposition to Disease; Graves Disease | 1994 |