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triiodothyronine and Gastrointestinal Stromal Tumors

triiodothyronine has been researched along with Gastrointestinal Stromal Tumors in 2 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Gastrointestinal Stromal Tumors: All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA).

Research Excerpts

ExcerptRelevanceReference
"Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib."6.71Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005)
"Eleven patients (1 with gastrointestinal stromal tumor and 10 with medullary thyroid carcinoma) received imatinib."2.71Imatinib induces hypothyroidism in patients receiving levothyroxine. ( de Groot, JW; Links, TP; Plukker, JT; van Der Graaf, WT; Zonnenberg, BA, 2005)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kappers, MH1
van Esch, JH1
Smedts, FM1
de Krijger, RR1
Eechoute, K1
Mathijssen, RH1
Sleijfer, S1
Leijten, F1
Danser, AH1
van den Meiracker, AH1
Visser, TJ1
de Groot, JW1
Zonnenberg, BA1
Plukker, JT1
van Der Graaf, WT1
Links, TP1

Trials

1 trial available for triiodothyronine and Gastrointestinal Stromal Tumors

ArticleYear
Imatinib induces hypothyroidism in patients receiving levothyroxine.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Benzamides; Carcinoma, Medullary; Drug Synergism; Female; Gastro

2005

Other Studies

1 other study available for triiodothyronine and Gastrointestinal Stromal Tumors

ArticleYear
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Aged; Animals; Antineoplastic Agents; Body Weight; Capillaries; Carcinoma, Renal Cell; Female; Gastr

2011