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triiodothyronine and Fetal Growth Restriction

triiodothyronine has been researched along with Fetal Growth Restriction in 16 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"This study comprised 46,186 mothers for whom early pregnancy thyrotropin (TSH), free thyroxine (fT4), triiodothyronine, thyroperoxidase antibodies, hCG, as well as ultrasound crown-rump length (CRL) measurements were available."3.91Association of Maternal Thyroid Function and Thyroidal Response to Human Chorionic Gonadotropin with Early Fetal Growth. ( Fan, J; Huang, HF; Korevaar, TIM; Liu, Z; Meng, Y; Peeters, RP; Yang, S; Yang, X; Zhang, C; Zhang, Y, 2019)
" The fetal growth retardation, hyperleptinemia, hyperinsulinism, and cytokines distortions (transforming growth factor-beta; TGF-β, tumor necrosis factor-alpha; TNF-α, and interferon-γ; IFN-γ) were noticed at examined EDs if compared to the control group."3.83Gestational dexamethasone alters fetal neuroendocrine axis. ( Ahmed, RG, 2016)
"Severe mental retardation of the child can occur due to compromised iodine intake or thyroid disease."2.43Thyroid hormones and fetal brain development. ( Franklyn, JA; Kilby, MD; Pemberton, HN, 2005)
" We postulate that altered TH bioavailability to trophoblasts may contribute to the pathogenesis of IUGR."1.36Differential triiodothyronine responsiveness and transport by human cytotrophoblasts from normal and growth-restricted pregnancies. ( Chan, SY; Franklyn, JA; Kilby, MD; Loubière, LS; Martín-Santos, A; McCabe, CJ; Vasilopoulou, E, 2010)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's4 (25.00)18.2507
2000's4 (25.00)29.6817
2010's4 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, Y1
Zhang, C1
Yang, X1
Yang, S1
Meng, Y1
Liu, Z1
Peeters, RP1
Huang, HF1
Korevaar, TIM1
Fan, J1
Uchida, K1
Taguchi, Y1
Sato, C1
Miyazaki, H1
Kobayashi, K1
Kobayashi, T1
Itoi, K1
Ahmed, RG1
Vasilopoulou, E1
Loubière, LS1
Martín-Santos, A1
McCabe, CJ2
Franklyn, JA4
Kilby, MD4
Chan, SY1
Chan, S1
Kachilele, S1
Hobbs, E1
Bulmer, JN1
Boelaert, K1
Driver, PM1
Bradwell, AR1
Kester, M1
Visser, TJ1
Pemberton, HN1
De Blasio, MJ1
Gatford, KL1
Robinson, JS1
Owens, JA1
Katricheva, LV1
Koroliuk, IP1
Mironov, NV1
Kaneko, S2
Hirano, T1
Fukushima, Y2
Sato, T2
Nomura, Y2
Shinagawa, S2
Ogawa, Y1
Sawa, H1
Wozikowska, J1
Kretowicz, W1
Narita, S1
Takebe, K1
Arai, K1
Ueda, S1
Serna, J1
González-Guerrero, PR1
Scanes, CG1
Prati, M1
Morreale, G1
de Pablo, F1
Verhaeg, J1
Gittoes, N1
Somerset, DA1
Clark, PM1
Pickard, MR1
Sinha, AK1
Ogilvie, LM1
Leonard, AJ1
Edwards, PR1
Ekins, RP1
Hiroi, H1
Kugu, K1
Hoshino, H1
Kozuma, S1
Taketani, Y1
Wrutniak, C1
Veyre, A1
Cabello, G1

Reviews

1 review available for triiodothyronine and Fetal Growth Restriction

ArticleYear
Thyroid hormones and fetal brain development.
    Minerva ginecologica, 2005, Volume: 57, Issue:4

    Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus;

2005

Other Studies

15 other studies available for triiodothyronine and Fetal Growth Restriction

ArticleYear
Association of Maternal Thyroid Function and Thyroidal Response to Human Chorionic Gonadotropin with Early Fetal Growth.
    Thyroid : official journal of the American Thyroid Association, 2019, Volume: 29, Issue:4

    Topics: Adult; Autoantibodies; Autoantigens; Biomarkers; Chorionic Gonadotropin; Crown-Rump Length; Female;

2019
Amelioration of improper differentiation of somatostatin-positive interneurons by triiodothyronine in a growth-retarded hypothyroid mouse strain.
    Neuroscience letters, 2014, Jan-24, Volume: 559

    Topics: Animals; Cell Differentiation; Female; Fetal Growth Retardation; Hypothyroidism; Interneurons; Male;

2014
Gestational dexamethasone alters fetal neuroendocrine axis.
    Toxicology letters, 2016, Sep-06, Volume: 258

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Dexamethasone; Endocrine Disruptors; Female; Fetal Dev

2016
Differential triiodothyronine responsiveness and transport by human cytotrophoblasts from normal and growth-restricted pregnancies.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:10

    Topics: Adult; Amino Acid Transport Systems, Neutral; Apoptosis; Biological Transport; Cell Survival; Cells,

2010
Placental iodothyronine deiodinase expression in normal and growth-restricted human pregnancies.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:9

    Topics: Adult; Choriocarcinoma; Female; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; H

2003
Placental restriction alters circulating thyroid hormone in the young lamb postnatally.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:4

    Topics: Animals; Animals, Newborn; Birth Weight; Body Composition; Body Weight; Eating; Fasting; Female; Fet

2006
[The hypophyseo-thyroid system in newborn infants with fetal growth retardation and in their mothers].
    Pediatriia, 1984, Issue:12

    Topics: Adult; Female; Fetal Growth Retardation; Growth Hormone; Humans; Infant, Newborn; Male; Maternal-Fet

1984
Foetal head growth retardation due to antiepileptic drugs: with reference to GH, TSH, T4, T3 and reverse T3 concentrations.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:1

    Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Infant,

1983
[Total thyroxine values, radiotriiodothyronine binding coefficient and free thyroxine index in newborn infants with intrauterine dystrophy syndrome and in eutrophic infants].
    Pediatria polska, 1982, Volume: 57, Issue:11

    Topics: Female; Fetal Growth Retardation; Humans; Infant, Low Birth Weight; Infant, Newborn; Pregnancy; Thyr

1982
[Fetal head growth retardation due to maternal antiepileptic drug use--with reference to GH, TSH, T4, T3 and R-T3].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:7

    Topics: Adult; Anticonvulsants; Epilepsy; Female; Fetal Growth Retardation; Growth Hormone; Humans; Pregnanc

1982
Differential and tissue-specific regulation of (pro)insulin and insulin-like growth factor-I mRNAs and levels of thyroid hormones in growth-retarded embryos.
    Growth regulation, 1996, Volume: 6, Issue:2

    Topics: Animals; Chick Embryo; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Growth H

1996
Circulating thyroid hormone concentrations and placental thyroid hormone receptor expression in normal human pregnancy and pregnancy complicated by intrauterine growth restriction (IUGR).
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:8

    Topics: Blotting, Western; Female; Fetal Blood; Fetal Growth Retardation; Gene Expression; Gestational Age;

1998
Maternal hypothyroxinemia influences glucose transporter expression in fetal brain and placenta.
    The Journal of endocrinology, 1999, Volume: 163, Issue:3

    Topics: Animals; Brain; Female; Fetal Growth Retardation; Gene Expression; Glucose Transporter Type 1; Gluco

1999
Hyperemesis gravidarum associated with thyrotoxicosis and a past history of an eating disorder.
    Archives of gynecology and obstetrics, 2001, Volume: 265, Issue:4

    Topics: Adult; Anorexia Nervosa; Antithyroid Agents; Female; Fetal Growth Retardation; Gestational Age; Huma

2001
Unusual features of neonatal thyroid function in small-for-gestational-age lambs. Origin of plasma T4 and T3 deficiencies.
    Journal of developmental physiology, 1990, Volume: 14, Issue:1

    Topics: Animals; Animals, Newborn; Birth Weight; Cold Temperature; Fetal Growth Retardation; Kinetics; Radio

1990