Page last updated: 2024-11-08

triiodothyronine and Fatigue

triiodothyronine has been researched along with Fatigue in 18 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
" The Zhongshan Station crew experienced significant increases in fatigue, anger, tension, confusion, and decrease in free thyroxine (FT4), norepinephrine (NE), and epinephrine (E) during the winter, increase in thyrotropin (TSH) and total triiodothyronine (TT3) when returning, whereas their counterparts at Great Wall Station only experienced increased TT3 after deployment."3.83Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence. ( Chen, N; Li, H; Wu, Q; Xu, C; Zhang, T, 2016)
"Hashimoto disease is a chronic autoimmune thyroiditis."2.90Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial. ( Bernklev, T; Carlsen, E; Gibbs, C; Guldvog, I; Hoff, G; Johnsen, L; Kvaløy, JT; Lauzike, A; Lende, TH; Narvestad, JK; Omdal, R; Reitsma, LC; Søiland, H, 2019)
"Subclinical hyperthyroidism is associated with atrial fibrillation, osteoporosis and dementia."2.42[Subclinical functional disorders of the thyroid gland]. ( Corssmit, EP; Wiersinga, WM, 2003)
"The association between fT4 and frailty was absent in our observational study."1.72Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study. ( Cao, J; Fan, L; Guan, B; Huang, X; Liu, R; Luo, J; Ma, Y; Sun, S; Tian, F; Yu, Y, 2022)
"High levels of tension-anxiety and confusion were preceded by declines in free T3 and T4."1.31Circannual pattern of hypothalamic-pituitary-thyroid (HPT) function and mood during extended antarctic residence. ( Case, HS; Do, NV; Finney, NS; Palinkas, LA; Reed, HL; Reedy, KR, 2001)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's0 (0.00)18.2507
2000's9 (50.00)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Guan, B3
Luo, J3
Huang, X3
Tian, F3
Sun, S3
Ma, Y3
Yu, Y3
Liu, R3
Cao, J3
Fan, L3
Guldvog, I1
Reitsma, LC1
Johnsen, L1
Lauzike, A1
Gibbs, C1
Carlsen, E1
Lende, TH1
Narvestad, JK1
Omdal, R1
Kvaløy, JT1
Hoff, G1
Bernklev, T1
Søiland, H1
Chen, N1
Wu, Q1
Li, H1
Zhang, T1
Xu, C1
Massolt, ET1
van der Windt, M1
Korevaar, TI1
Kam, BL1
Burger, JW1
Franssen, GJ1
Lehmphul, I1
Köhrle, J1
Visser, WE1
Peeters, RP1
Bunevicius, A1
Gintauskiene, V1
Podlipskyte, A1
Zaliunas, R1
Brozaitiene, J1
Prange, AJ1
Bunevicius, R1
Scally, MC1
Hodge, A1
Corssmit, EP1
Wiersinga, WM1
Jellinger, PS1
Anolik, JR1
Pinchera, A1
Santini, F1
Kilic, M1
Palinkas, LA1
Reed, HL1
Reedy, KR1
Do, NV1
Case, HS1
Finney, NS1
Parikh, S1
Ando, S1
Schneider, A1
Skarulis, MC1
Sarlis, NJ1
Yen, PM1
Bauer, BA1
Elkin, PL1
Erickson, D1
Klee, GG1
Brennan, MD1
Himms-Hagen, J1
Dymling, JF1
Becker, DV1
Nelson, JH1
Fairclough, PD1
Besser, GM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Surgical Treatment of Hashimotos Disease. Effect on Antibodies and Clinical Symptoms.[NCT02319538]150 participants (Actual)Interventional2012-02-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for triiodothyronine and Fatigue

ArticleYear
[Subclinical functional disorders of the thyroid gland].
    Nederlands tijdschrift voor geneeskunde, 2003, Jun-14, Volume: 147, Issue:24

    Topics: Depression; Fatigue; Humans; Hyperthyroidism; Hypothyroidism; Risk Factors; Thyroid Diseases; Thyroi

2003

Trials

2 trials available for triiodothyronine and Fatigue

ArticleYear
Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial.
    Annals of internal medicine, 2019, 04-02, Volume: 170, Issue:7

    Topics: Adolescent; Adult; Aged; Antibodies; Drug Therapy, Combination; Fatigue; Female; Follow-Up Studies;

2019
Effect of fatiguing bicycle exercise on thyroid hormone and testosterone levels in sedentary males supplemented with oral zinc.
    Neuro endocrinology letters, 2007, Volume: 28, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Dietary Supplements; Exercise; Exercise Test; Fatigue; Huma

2007

Other Studies

15 other studies available for triiodothyronine and Fatigue

ArticleYear
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Association between thyroid hormone levels and frailty in the community-dwelling oldest-old: a cross-sectional study.
    Chinese medical journal, 2022, Aug-20, Volume: 135, Issue:16

    Topics: Aged; Aged, 80 and over; Cross-Sectional Studies; Fatigue; Frailty; Humans; Hypothyroidism; Independ

2022
Different adaptations of Chinese winter-over expeditioners during prolonged Antarctic and sub-Antarctic residence.
    International journal of biometeorology, 2016, Volume: 60, Issue:5

    Topics: Adaptation, Physiological; Adult; Affect; Anger; Antarctic Regions; Asian People; Depression; Dopami

2016
Thyroid hormone and its metabolites in relation to quality of life in patients treated for differentiated thyroid cancer.
    Clinical endocrinology, 2016, Volume: 85, Issue:5

    Topics: Fatigue; Female; Humans; Male; Middle Aged; Quality of Life; Thyroid Function Tests; Thyroid Hormone

2016
Fatigue in patients with coronary artery disease: association with thyroid axis hormones and cortisol.
    Psychosomatic medicine, 2012, Volume: 74, Issue:8

    Topics: Adrenal Glands; Coronary Artery Disease; Cross-Sectional Studies; Exercise Test; Exercise Tolerance;

2012
A report of hypothyroidism induced by an over-the-counter fat loss supplement (Tiratricol).
    International journal of sport nutrition and exercise metabolism, 2003, Volume: 13, Issue:1

    Topics: Adult; Anti-Obesity Agents; Diet, Fat-Restricted; Dietary Supplements; Fatigue; Female; Humans; Hypo

2003
Acquired hypothyroidism after switching from thyroid USP to levothyroxine.
    Clinical cornerstone, 2005, Volume: 7 Suppl 2

    Topics: Depression; Drug Therapy, Combination; Fatigue; Female; Hormone Replacement Therapy; Humans; Hypothy

2005
Hypothyroid symptoms following radioiodine therapy for Graves' disease.
    Clinical cornerstone, 2005, Volume: 7 Suppl 2

    Topics: Antithyroid Agents; Drug Therapy, Combination; Fatigue; Graves Disease; Humans; Hypothyroidism; Iodi

2005
Is combined therapy with levothyroxine and liothyronine effective in patients with primary hypothyroidism?
    Nature clinical practice. Endocrinology & metabolism, 2005, Volume: 1, Issue:1

    Topics: Affect; Double-Blind Method; Drug Therapy, Combination; Fatigue; Humans; Hypothyroidism; Prospective

2005
Circannual pattern of hypothalamic-pituitary-thyroid (HPT) function and mood during extended antarctic residence.
    Psychoneuroendocrinology, 2001, Volume: 26, Issue:4

    Topics: Adult; Affect; Anger; Antarctic Regions; Confusion; Depression; Fatigue; Female; Humans; Hypothalamu

2001
Resistance to thyroid hormone in a patient without thyroid hormone receptor mutations.
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:1

    Topics: Adult; DNA-Binding Proteins; Fatigue; Female; Goiter; Humans; Intelligence Tests; Mutation; National

2002
Symptomatic hyperthyroidism in a patient taking the dietary supplement tiratricol.
    Mayo Clinic proceedings, 2002, Volume: 77, Issue:6

    Topics: Aged; Aged, 80 and over; Anxiety; Dietary Supplements; Fatigue; Female; Humans; Hyperthyroidism; Med

2002
Food restriction increases torpor and improves brown adipose tissue thermogenesis in ob/ob mice.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Adipose Tissue, Brown; Animals; Basal Metabolism; Body Temperature; Body Weight; Circadian Rhythm; E

1985
Occurrence of hyperthyroidism in patients receiving thyroid hormone.
    The Journal of clinical endocrinology and metabolism, 1967, Volume: 27, Issue:10

    Topics: Adolescent; Adult; Alopecia; Antithyroid Agents; Fatigue; Female; Goiter; Graves Disease; Humans; Hy

1967
Selecting the optimum oral contraceptive.
    The Journal of reproductive medicine, 1973, Volume: 11, Issue:4

    Topics: Acne Vulgaris; Blood Coagulation Disorders; Brain Edema; Breast; Candidiasis; Capillaries; Carbohydr

1973
Apathetic T-3 toxicosis.
    British medical journal, 1974, Mar-02, Volume: 1, Issue:5904

    Topics: Adult; Body Weight; Carbimazole; Fatigue; Female; Humans; Hyperthyroidism; Iodine Radioisotopes; Pro

1974