Page last updated: 2024-11-08

triiodothyronine and Eye Diseases

triiodothyronine has been researched along with Eye Diseases in 16 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Eye Diseases: Diseases affecting the eye.

Research Excerpts

ExcerptRelevanceReference
" The study consisted of an untreated control group and five treatment groups that received continuous exposure to AP via the drinking water at dosage levels of 0."1.31A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate. ( Baker, WH; Dodd, DE; Hildebrandt, PK; Mattie, DR; Siglin, JC, 2000)
"Euthyroid Graves' disease is defined as Graves' ophthalmopathy without hyperthyroidism, and the thyroid-stimulating antibody (TSAb) has been known to be a good marker for diagnosis."1.30Low response of the thyroid gland to endogenous thyrotropin increased by thyrotropin-releasing hormone in patients with euthyroid Graves' disease. ( Amino, N; Fujikado, T; Hidaka, Y; Kashiwai, T; Shimaoka, Y; Tada, H; Watanabe, Y; Yagoro, A, 1998)
"We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years."1.29Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease. ( Amino, N; Asahi, K; Hidaka, Y; Iwatani, Y; Kashiwai, T; Tada, H; Tamaki, H, 1995)
"The patients had Graves' disease, but no other immune-mediated diseases, had not yet received specific treatment for their ophthalmopathy and were euthyroid during the entire study period."1.28Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy. ( Koornneef, L; Mourits, MP; Prummel, MF; Van der Gaag, R; Wiersinga, WM, 1992)
" Group A patients (n = 31) received either methimazole (40-100 mg daily) or propylthiouracil (400-900 mg daily) combined with T3 daily throughout treatment."1.28The evolution of Graves' ophthalmopathy during treatment with antithyroid drug alone and combined with triiodothyronine. ( Bromberg, N; Romaldini, JH; Sgarbi, JA; Werner, MC; Werner, RS, 1992)
"Thyroidal Graves' disease--past or present--was clinically evident in 99 patients (79%): hyperthyroidism in 3 cases."1.27Temporal relationship between onset of Graves' ophthalmopathy and onset of thyroidal Graves' disease. ( Koornneef, L; Smit, T; van der Gaag, R; Wiersinga, WM, 1988)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's6 (37.50)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kashiwai, T2
Tada, H2
Asahi, K1
Hidaka, Y2
Tamaki, H1
Iwatani, Y1
Amino, N2
Watanabe, Y1
Shimaoka, Y1
Yagoro, A1
Fujikado, T1
Siglin, JC1
Mattie, DR1
Dodd, DE1
Hildebrandt, PK1
Baker, WH1
Fells, P1
Prummel, MF1
Wiersinga, WM2
Van der Gaag, R2
Mourits, MP1
Koornneef, L2
Bromberg, N1
Romaldini, JH1
Werner, RS1
Sgarbi, JA1
Werner, MC1
Gomez, JM1
Soler, J1
Navarro, MA1
Imai, Y1
Odajima, R1
Shimizu, T1
Shishiba, Y1
Smit, T1
Klein, E2
Heinze, HG1
Pabst, HW1
Klemm, J1
Hör, G1
Mahaux, JE1
Nagel, M1
Hollows, FC1
Beaumont, P1
Schneider, C1
Hesch, RD1
Horster, FA1
Reinwein, D1

Reviews

2 reviews available for triiodothyronine and Eye Diseases

ArticleYear
[Results of the thyroid gland function diagnosis with radioiodine in hyperthyroidism and endocrine ophthalmopathies].
    Nuclear-Medizin, 1965

    Topics: Exophthalmos; Eye Diseases; Humans; Hyperthyroidism; Iodine Radioisotopes; Protein Binding; Radionuc

1965
Thyroid eye disease and its relationship to the long-acting thyroid stimulator.
    Transactions of the Australian College of Ophthalmologists, 1969, Volume: 1

    Topics: Biological Assay; Conjunctiva; Eye Diseases; Eye Movements; Eyelid Diseases; Female; Glycosaminoglyc

1969

Other Studies

14 other studies available for triiodothyronine and Eye Diseases

ArticleYear
Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease.
    Endocrine journal, 1995, Volume: 42, Issue:3

    Topics: Adult; Aged; Exophthalmos; Eye Diseases; Female; Graves Disease; Humans; Immunoglobulins, Thyroid-St

1995
Low response of the thyroid gland to endogenous thyrotropin increased by thyrotropin-releasing hormone in patients with euthyroid Graves' disease.
    Thyroid : official journal of the American Thyroid Association, 1998, Volume: 8, Issue:10

    Topics: Adolescent; Adult; Eye Diseases; Female; Graves Disease; Humans; Hyperthyroidism; Immunoglobulins, T

1998
A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:1

    Topics: Animals; Body Weight; Drinking; Eating; Estrus; Eye Diseases; Female; Male; Micronucleus Tests; Orga

2000
Surgical management of dysthyroid eye disease: a review.
    Proceedings of the Royal Society of Medicine, 1977, Volume: 70, Issue:10

    Topics: Eye Diseases; Humans; Thyroid Diseases; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1977
Soluble IL-2 receptor levels in patients with Graves' ophthalmopathy.
    Clinical and experimental immunology, 1992, Volume: 88, Issue:3

    Topics: Adult; Eye Diseases; Female; Graves Disease; Humans; Male; Middle Aged; Predictive Value of Tests; P

1992
The evolution of Graves' ophthalmopathy during treatment with antithyroid drug alone and combined with triiodothyronine.
    Journal of endocrinological investigation, 1992, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Autoantibodies; Drug Therapy, Combination; Eye Diseases; Female; Graves Disease;

1992
Thyroid stimulating antibodies in patients with Graves' ophthalmopathy.
    Thyroidology, 1991, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Antibodies; Cyclic AMP; Eye Diseases; Female; Graves Disease; Humans; In Vitro Te

1991
Serum hyaluronan concentration determined by radiometric assay in patients with pretibial myxedema and Graves' ophthalmopathy.
    Endocrinologia japonica, 1990, Volume: 37, Issue:5

    Topics: Adult; Autoantibodies; Eye Diseases; Female; Graves Disease; Humans; Hyaluronic Acid; Immunoglobulin

1990
Temporal relationship between onset of Graves' ophthalmopathy and onset of thyroidal Graves' disease.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:8

    Topics: Adult; Aged; Eye Diseases; Female; Graves Disease; Humans; Immunoglobulin G; Immunoglobulins, Thyroi

1988
[l-Triiodothyronine suppression test of the thyroid gland].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:10

    Topics: Eye Diseases; Humans; Iodine Radioisotopes; Methods; Pituitary Hormone-Releasing Hormones; Thyroid D

1967
[Basdowian ophthalmic diseases. Pathogenic role of L-triiodothyronine and of LATS. Therapeutic role of L-thyroxine, of d-thyroxine and of corticoids].
    Bruxelles medical, 1967, Oct-22, Volume: 47, Issue:43

    Topics: Antithyroid Agents; Betamethasone; Dextrothyroxine; Eye Diseases; Graves Disease; Humans; Hyperthyro

1967
[Treatment of endocrine ophthalmopathy].
    Fortschritte der Medizin, 1974, Aug-22, Volume: 92, Issue:22

    Topics: Endocrine System Diseases; Eye Diseases; Glucocorticoids; Humans; Hyperthyroidism; Hypnotics and Sed

1974
[Triiodothyronine hyperthyroidism in endocrine ophthalmopathy].
    Deutsche medizinische Wochenschrift (1946), 1972, Nov-24, Volume: 97, Issue:47

    Topics: Eye Diseases; Humans; Hyperthyroidism; Triiodothyronine

1972
[On drug therapy of endocrine ophthalmopathy].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1967, Volume: 73

    Topics: Edema; Exophthalmos; Eye Diseases; Eyelids; Humans; Long-Acting Thyroid Stimulator; Prednisone; Thyr

1967