triiodothyronine has been researched along with Experimental Neoplasms in 57 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A cytotoxic effect of this system on a line of mouse ascitic lymphoma cells (LSTRA) is demonstrated here using four different assay systems: 51Cr release, trypan blue exclusion, inhibition of glucose C-1 oxidation, and loss of oncogenicity for mice." | 3.65 | Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells. ( Clark, RA; Einstein, AB; Fefer, A; Klebanoff, SJ, 1975) |
| " Groups of five male and five female Fischer rats and B6C3F1 mice were administered 2MI by dosed feed at 0, 1,200, 3,300, or 10,000 ppm or 4MI at 0, 300, 800, or 2,500 ppm for 15 days, and groups of 10 male and 10 female Fischer rats and B6C3F1 mice were administered 2MI or 4MI at 0, 625, 1,250, 2,500, 5,000 or 10,000 ppm for 14 weeks." | 1.33 | Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. ( Chan, P; Mahler, J; Nyska, A; Travlos, G; Wenk, M, 2006) |
| "ZR-75-1, a human breast cancer cell line, has been grown in hormone-supplemented medium without serum." | 1.26 | Growth of a human breast cancer cell line in serum-free hormone-supplemented medium. ( Allegra, JC; Lippman, ME, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 53 (92.98) | 18.7374 |
| 1990's | 1 (1.75) | 18.2507 |
| 2000's | 3 (5.26) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHRISTENSEN, HN | 1 |
| HESS, B | 1 |
| RIGGS, TR | 1 |
| STEIN, JA | 1 |
| GRIEM, ML | 1 |
| HUMPHREY, LJ | 1 |
| HOPPE, ET | 1 |
| DEPEYSTER, FA | 1 |
| SHERWIN-WEIDENREICH, R | 1 |
| HERRMANN, F | 2 |
| SIRACKA, E | 3 |
| KNOTZ, F | 1 |
| PITTMAN, CS | 1 |
| LIU, A | 1 |
| JONES, EE | 1 |
| SALVATORE, G | 1 |
| CHERNOV, VA | 1 |
| GRUSHINA, AA | 1 |
| SORKINA, YA | 1 |
| BACIGALUPO, G | 1 |
| WEIDENREICH-SHERWIN, R | 1 |
| SIRACKY, J | 1 |
| GRINBERG, R | 2 |
| VOLPERT, EM | 3 |
| WERNER, SC | 2 |
| Chan, P | 1 |
| Mahler, J | 1 |
| Travlos, G | 1 |
| Nyska, A | 1 |
| Wenk, M | 1 |
| Stora, C | 2 |
| Aussel, C | 2 |
| Lafaurie, M | 2 |
| Formento, JL | 2 |
| Halpern, J | 1 |
| Hinkle, PM | 1 |
| Horiuchi, R | 1 |
| Johnson, ML | 1 |
| Willingham, MC | 1 |
| Pastan, I | 1 |
| Cheng, S | 1 |
| Sokolov, IaA | 1 |
| Chlok, TA | 1 |
| Serova, TA | 1 |
| Cacicedo, L | 1 |
| Pohl, SL | 1 |
| Reichlin, S | 1 |
| Melmed, S | 1 |
| Park, J | 1 |
| Hershman, JM | 1 |
| Arnold, DL | 1 |
| Krewski, DR | 1 |
| Junkins, DB | 1 |
| McGuire, PF | 1 |
| Moodie, CA | 1 |
| Munro, IC | 1 |
| Borek, C | 1 |
| Hall, EJ | 1 |
| Milmore, JE | 1 |
| Chandrasekaran, V | 1 |
| Weisburger, JH | 1 |
| Castelli, D | 1 |
| Spindler, SR | 1 |
| Mellon, SH | 1 |
| Baxter, JD | 2 |
| Ivarie, RD | 1 |
| Morris, JA | 1 |
| Jemec, B | 1 |
| DeFesi, CR | 1 |
| Surks, MI | 2 |
| Hupart, KH | 1 |
| Hodin, RA | 1 |
| Lazar, MA | 1 |
| Shapiro, LE | 1 |
| Chin, WW | 1 |
| Charles, JM | 1 |
| Tobia, A | 1 |
| van Ravenzwaay, B | 1 |
| Yasuhara, K | 1 |
| Koujitani, T | 1 |
| Takegawa, K | 1 |
| Nasu, M | 1 |
| Onodera, H | 1 |
| Takagi, H | 1 |
| Hirose, M | 1 |
| Mitsumori, K | 1 |
| Brocas, H | 1 |
| Seo, H | 1 |
| Refetoff, S | 1 |
| Vassart, G | 1 |
| Dumont, JE | 1 |
| Eto, S | 1 |
| Fleischer, N | 1 |
| Venter, BR | 1 |
| Venter, JC | 1 |
| Kaplan, NO | 1 |
| Burke, RE | 1 |
| McGuire, WL | 1 |
| Allegra, JC | 1 |
| Lippman, ME | 1 |
| Gershengorn, MC | 1 |
| Prezyma, AP | 1 |
| Al-Hindawi, AY | 1 |
| Black, EG | 1 |
| Brewer, DB | 1 |
| Griffiths, SG | 1 |
| Hoffenberg, R | 1 |
| Kirkland, WL | 1 |
| Sorrentino, JM | 1 |
| Sirbasku, DA | 1 |
| Clark, RA | 1 |
| Klebanoff, SJ | 1 |
| Einstein, AB | 1 |
| Fefer, A | 1 |
| Monaco, F | 1 |
| Grimaldi, S | 1 |
| Dominici, R | 1 |
| Robbins, J | 1 |
| Hiasa, Y | 1 |
| Ohshima, M | 1 |
| Kitahori, Y | 1 |
| Konishi, N | 1 |
| Shimoyama, T | 1 |
| Sakaguchi, Y | 1 |
| Hashimoto, H | 1 |
| Minami, S | 1 |
| Kato, Y | 1 |
| Kubota, K | 1 |
| Kubota, R | 1 |
| Matsuzawa, T | 1 |
| Dedenkov, AN | 1 |
| Petrova, GA | 1 |
| Smoryzanova, OA | 1 |
| Norets, TA | 1 |
| Vereshchagina, GV | 1 |
| Gurr, JA | 1 |
| Kourides, IA | 1 |
| Ronzoni, G | 1 |
| Alquati, P | 1 |
| Pola, P | 1 |
| Alcini, E | 1 |
| Hunt, SM | 1 |
| Osnos, M | 1 |
| Rivlin, RS | 1 |
| Karsten, U | 1 |
| Sydow, G | 1 |
| Wollenberger, A | 1 |
| Graffi, A | 1 |
| Horvat, NM | 1 |
| Horvat, BL | 1 |
| Milković, K | 1 |
| Milković, S | 1 |
| Wu, C | 1 |
| al-Saadi, AA | 1 |
| Ling, RC | 1 |
| McKinnie, KL | 1 |
| Habighorst, LV | 1 |
| Diethelm, L | 1 |
| Amoroso, AC | 1 |
| Schatten, WE | 1 |
| Burson, JL | 1 |
| Tierney, J | 1 |
| Messier, B | 1 |
| Fisher, ER | 1 |
| Fisher, B | 1 |
57 other studies available for triiodothyronine and Experimental Neoplasms
| Article | Year |
|---|---|
Concentration of taurine, beta-alanine, and triiodothyronine by ascites carcinoma cells.
Topics: Alanine; Animals; Ascites; beta-Alanine; Bile Acids and Salts; Humans; Neoplasms, Experimental; Salt | 1954 |
Effect of triiodothyronine on radiosensitivity.
Topics: Animals; Neoplasms, Experimental; Radiation Tolerance; Triiodothyronine; X-Rays | 1958 |
The action of 3,5,3 L-triiodothyronine and nitrogen mustard on the take of the Walker 256 rat tumor.
Topics: Animals; Mechlorethamine; Neoplasms; Neoplasms, Experimental; Nitrogen Mustard Compounds; Rats; Trii | 1958 |
Hair cycle and chemically induced epidermal carcinogenesis in mice receiving tri-iodothyronine. I. Findings after single application of 9,10-dimethyl-1,2-benzanthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogenesis; Epidermis; Hair; Mice | 1963 |
AN ATTEMPT TO INCREASE THE RADIOSENSITIVITY OF EXPERIMENTAL TUMOURS BY INDUCING A STATE OF HYPERMETABOLISM.
Topics: Animals; Metabolism; Neoplasms; Neoplasms, Experimental; Radiation Effects; Radiation Tolerance; Rat | 1963 |
HORMONE SYNTHESIS BY A TRANSPLANTABLE THYROID TUMOR IN MICE.
Topics: Adenoma; Chromatography; Diiodotyrosine; Iodine Isotopes; Metabolism; Mice; Neoplasms, Experimental; | 1963 |
[INTRACELLULAR PENETRATION OF THYROID HORMONES].
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Electrophoresis; Erythrocytes; Escheri | 1964 |
THE EFFECT PRODUCED BY SOME HORMONES ON THE ANTITUMOUR ACTIVITY OF ETHYLENIMINE AND BETA-CHLORETHYLAMINE DERIVATIVES.
Topics: Adrenocorticotropic Hormone; Antineoplastic Agents; Aziridines; Cortisone; Growth Hormone; Neoplasms | 1964 |
UNCOUPLING THE OXIDATIVE PHOSPHORYLATION IN THE COMBINED CHEMOTHERAPY OF CANCER.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carcinoma 256, Walker; Chlorpromazin | 1964 |
HAIR CYCLE AND CHEMICALLY INDUCED EPIDERMAL CARCINOGENESIS IN MICE RECEIVING LIOTHYRONINE. II. FINDINGS AFTER MULTIPLE APPLICATIONS OF METHYLCHOLANTHRENE.
Topics: Animals; Carcinogenesis; Epidermis; Hair; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experiment | 1964 |
THE RELATIONSHIP BETWEEN THE RADIOSENSITIVITY AND THE SIZE OF TUMORS IRRADIATED IN A STATE OF HYPERMETABOLISM INDUCED BY 3-5-3-L TRIIODOTHYRONINE.
Topics: Blood Circulation; Metabolism; Neoplasms; Neoplasms, Experimental; Pathology; Pharmacology; Radiatio | 1964 |
BINDING OF 131-I-LABELED THYROXINE AND TRIIODOTHYRONINE BY AQUEOUS DISPERSIONS OF THYROTROPIC AND MAMMOTROPIC TUMORS.
Topics: Animals; Beta-Globulins; Blood; Electrophoresis; Iodine Isotopes; Mammary Neoplasms, Animal; Mammary | 1964 |
METABOLISM OF LABELLED THYROID HORMONE BY THYROTROPIC AND ADRENOTROPIC MOUSE PITUITARY TUMORS.
Topics: Animals; Autoradiography; Chromatography; Iodine Isotopes; Kidney; Mammary Neoplasms, Animal; Mammar | 1964 |
Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hyperplasia; Hypertrophy; Imidazoles; Incidence; | 2006 |
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide.
Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Female; Liver Neoplasms; Neoplasms, Experimental | 1981 |
Evidence for an active step in thyroid hormone transport to nuclei: drug inhibition of L-125I-triiodothyronine binding to nuclear receptors in rat pituitary tumor cells.
Topics: Animals; Antineoplastic Agents; Biological Transport, Active; Cadaverine; Cell Line; Cell Nucleus; C | 1982 |
Affinity labeling of the plasma membrane 3,3',5-triiodo-L-thyronine receptor in GH3 cells.
Topics: Affinity Labels; Animals; Binding, Competitive; Cell Line; Cell Membrane; Kinetics; Neoplasms, Exper | 1982 |
[Immunohormonal homeostasis in meningococcal meningitis].
Topics: Animals; Diabetes Mellitus, Experimental; Factor Analysis, Statistical; Guinea Pigs; Homeostasis; Hu | 1984 |
Effects of thyroid hormones and thyrotropin-releasing hormone on thyrotropin biosynthesis by mouse pituitary tumor cells in vitro.
Topics: Animals; Cells, Cultured; Mice; Neoplasms, Experimental; Pituitary Neoplasms; Proline; Thyroid Hormo | 1981 |
Triiodothyronine induces a transferable factor which suppresses TSH secretion in cultured mouse thyrotropic tumor cells.
Topics: Animals; Cells, Cultured; Cycloheximide; Dactinomycin; Female; In Vitro Techniques; Methotrexate; Mi | 1981 |
Reversibility of ethylenethiourea-induced thyroid lesions.
Topics: Adenoma; Animals; Body Weight; Carcinoma; Diet; Dose-Response Relationship, Drug; Ethylenethiourea; | 1983 |
Oncogenic transformation produced by agents and modalities used in cancer therapy and its modulation.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetina | 1982 |
Effects of hypothyroidism on development of nitrosomethylurea-induced tumors of the mammary gland, thyroid gland, and other tissues.
Topics: Animals; Female; Hypothyroidism; Kidney Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; | 1982 |
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide in the male rat.
Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Male; Neoplasms, Experimental; Pituitary Gland; Rat | 1982 |
Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.
Topics: Animals; Cell Line; Cell Nucleus; Dexamethasone; DNA-Directed RNA Polymerases; Genes; Growth Hormone | 1982 |
Interaction of thyroid and glucocorticoid hormones in rat pituitary tumor cells. Specificity and diversity of the responses analyzed by two-dimensional gel electrophoresis.
Topics: Animals; Cell Line; Dexamethasone; Electrophoresis, Polyacrylamide Gel; Growth Hormone; Neoplasm Pro | 1981 |
Studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment.
Topics: Adenoma; Adrenal Glands; Animals; Body Weight; Drug Combinations; Hyperplasia; Hypophysectomy; Imida | 1980 |
3,5,3'-Triiodothyronine effects on the growth rate and cell cycle of cultured GC cells.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Growth Hormone; Mitosis; Neoplasms, Experimental; Pitu | 1981 |
c-erb-A mRNA correlates with T3-receptor levels in liver and pituitary of tumor rats.
Topics: Animals; Cell Nucleus; Liver; Male; Neoplasms, Experimental; Pituitary Gland, Anterior; Proto-Oncoge | 1993 |
Subchronic and chronic toxicological investigations on metiram: the lack of a carcinogenic response in rodents.
Topics: Animals; Body Weight; Carcinogenicity Tests; Clinical Chemistry Tests; Diet; Ditiocarb; Female; Fung | 2000 |
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.
Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Hyp | 2001 |
Translation of prolactin and growth hormone messenger RNA from rat pituitary tumour cells. Stimulation of GH mRNA activity by triiodothyronine [proceedings].
Topics: Cells, Cultured; Growth Hormone; Neoplasms, Experimental; Pituitary Neoplasms; Prolactin; Protein Bi | 1977 |
Regulation of thyrotropin (TSH) release and production in monolayer cultures of transplantable TSH-producing mouse tumors.
Topics: Adenylyl Cyclases; Animals; Calcium; Culture Techniques; Cyclic AMP; Depression, Chemical; Mice; Mod | 1976 |
Affinity isolation of cultured tumor cells by means of drugs and hormones covalently bound to glass and Sepharose beads.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Cell Membrane; Cell Separation; Cells | 1976 |
Nuclear thyroid hormone receptors in a human breast cancer cell line.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Humans; Kinetics; Ne | 1978 |
Growth of a human breast cancer cell line in serum-free hormone-supplemented medium.
Topics: Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Cell Division; Cell Line; Cell Survival; | 1978 |
Bihormonal regulation of the thyrotropin-releasing hormone receptor in mouse pituitary thyrotropic tumor cells in culture.
Topics: Cells, Cultured; Neoplasms, Experimental; Pituitary Neoplasms; Receptors, Cell Surface; Thyrotropin; | 1978 |
Transplantable thyroid tumour in rats: iodoamino acid distribution in successive tumour generations.
Topics: Amino Acids; Animals; Diiodotyrosine; Female; Iodine Radioisotopes; Neoplasm Transplantation; Neopla | 1977 |
Measurement of thyroid hormone in experimental thyroid tumours in rats.
Topics: Animals; Iodine Radioisotopes; Male; Neoplasms, Experimental; Propylthiouracil; Rats; Thyroid Neopla | 1977 |
Control of cell growth. III. Direct mitogenic effect of thyroid hormones on an estrogen-dependent rat pituitary tumor cell line.
Topics: Adrenalectomy; Castration; Cell Division; Cell Line; Cells, Cultured; Culture Media; Estrogens; Neop | 1976 |
Peroxidase-H2O2-halide system: Cytotoxic effect on mammalian tumor cells.
Topics: Animals; Ascitic Fluid; Carbon Dioxide; Carbon Radioisotopes; Carcinogens; Chromium Radioisotopes; F | 1975 |
Defective thyroglobulin synthesis in an experimental rat thyroid tumor: iodination and thyroid hormone synthesis in isolated tumor thyroglobulin.
Topics: Animals; Iodine; Iodine Radioisotopes; Neoplasms, Experimental; Rats; Sialic Acids; Thyroglobulin; T | 1975 |
The promoting effects of food dyes, erythrosine (Red 3) and rose bengal B (Red 105), on thyroid tumors in partially thyroidectomized N-bis(2-hydroxypropyl)-nitrosamine-treated rats.
Topics: Animals; Body Weight; Coloring Agents; Erythrosine; Fluoresceins; Food Coloring Agents; Liver; Male; | 1988 |
Growth and differentiation of teratocarcinoma OTT6050 affected by host hormonal changes in old mice.
Topics: Aging; Animals; Cell Differentiation; Estradiol; Female; Hormones; Male; Mice; Neoplasms, Experiment | 1987 |
[Accumulation of 125J-triiodothyronine in the transplanted tumors of mice and rats].
Topics: Animals; Iodine Radioisotopes; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rats; | 1986 |
Thyroid hormone regulation of thyrotropin alpha- and beta-subunit gene transcription.
Topics: Animals; Cell Nucleus; Cell-Free System; Gene Expression Regulation; Macromolecular Substances; Male | 1985 |
[Study of prostatic carcinogenesis, using 20-methyl-cholanthrene in albino rats].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Carcinoma, Squamous Cell; Hormones; Male; Meth | 1968 |
Thyroid hormone regulation of mitochondrial alpha-glycerophosphate dehydrogenase in liver and hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Enzyme Induction; Glycerolphosphate Dehydrogenase; Liver Neoplas | 1970 |
Rat liver glycerolphosphate dehydrogenases: activity changes and induction by thyroid hormone of the mitochondrial enzyme in hepatomas and in precancerous and growing liver.
Topics: Animals; Carcinoma, Hepatocellular; Cytoplasm; Enzyme Induction; Female; Glycerolphosphate Dehydroge | 1971 |
Influence of high level of endogenous Glucocorticoids on the histology of fetal rat thyroid.
Topics: Adrenal Glands; Animals; Female; Glucocorticoids; Hormones, Ectopic; Hyperplasia; Neoplasm Transplan | 1973 |
Some biochemical and cytogenetic properties of rat thyroid tumors.
Topics: Amino Acids; Aneuploidy; Animals; Chromosome Aberrations; Iodine; Iodine Isotopes; Karyotyping; Mono | 1971 |
Fractionated radiation, thyroid hormone and transplantability of tumor cells.
Topics: Animals; Carcinoma 256, Walker; Female; Injections, Intravenous; Neoplasm Transplantation; Neoplasms | 1968 |
[Animal experimental studies on preoperative tumor irradiation].
Topics: Animals; Neoplasms, Experimental; Rats; Serotonin; Triiodothyronine; Vitamin K | 1968 |
Effect of altering blood flow on necrosis in tumors.
Topics: Animals; Atmospheric Pressure; Carcinoma 256, Walker; Hypotension, Controlled; Necrosis; Neoplasm Tr | 1965 |
Studies with mouse pituitary thyrotropic tumors. X. Formation in vitro of 3,5,3'-triiodothyronine from thyroxine by dependent but not autonomous strains.
Topics: Animals; Chromatography, Paper; In Vitro Techniques; Mice; Neoplasms, Experimental; Pituitary Neopla | 1966 |
Action of thyroid hormones and diethylstilbestrol on the gonadotropic activity of a mouse thyrotropic tumor.
Topics: Animals; Diethylstilbestrol; Female; Gonadotropins; Gonads; Male; Mice; Neoplasms, Experimental; Pit | 1966 |
Experimental studies of factors influencing development of hepatic metastases. XVII. Role of thyroid.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Female; Hypothyroidism; Liver Neoplasms; | 1966 |