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triiodothyronine and Experimental Mammary Neoplasms

triiodothyronine has been researched along with Experimental Mammary Neoplasms in 20 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
" Animals were either euthyroid or made hyperthyroid (by ingestion of thyroxine) or hypothyroid (by ingestion of 2-thiouracil) during involution."3.66Effect of thyroid status on development of spontaneous mammary tumors in primiparous C3H mice. ( Greco, AE; Vonderhaar, BK, 1982)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199017 (85.00)18.7374
1990's3 (15.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SHIMA, T1
GRINBERG, R2
VOLPERT, EM1
WERNER, SC1
Natoli, C1
Sica, G1
Natoli, V1
Scambia, G1
Iacobelli, S1
Ruzicka, FJ1
Rose, DP1
Goodman, AD1
Hoekstra, SJ1
Marsh, PS1
Greengard, O1
Cayanis, E1
Milmore, JE1
Chandrasekaran, V1
Weisburger, JH1
Vonderhaar, BK1
Greco, AE1
Sellitti, DF1
Tseng, YC1
Latham, KR1
Gerard, SS1
Gardner, B1
Patti, J1
Husain, V1
Shouten, J1
Alfonso, AE1
Nagasawa, H1
Yanai, R1
Nakajima, Y1
Namiki, H1
Kikuyama, S1
Shiota, K1
Sumitani, S2
Kasayama, S2
Sato, B2
Prough, RA1
Lei, XD1
Xiao, GH1
Wu, HQ1
Geoghegan, TE1
Webb, SJ1
Cave, WT1
Dunn, JT1
MacLeod, RM1
Hirose, T1
Matsumoto, K1
de Launoit, Y1
Kiss, R1
Ong, ML1
Kellen, JA1
Malkin, DG1
Malkin, A1
Hosick, HL1
Nandi, S1
Du Sult, LA1

Other Studies

20 other studies available for triiodothyronine and Experimental Mammary Neoplasms

ArticleYear
[Effects of L-triiodothyronine on growth and radiosensitivity of tumors. 1].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Feb-25, Volume: 22

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Division; Mammary Neoplasms, Animal; Mammary Neop

1963
BINDING OF 131-I-LABELED THYROXINE AND TRIIODOTHYRONINE BY AQUEOUS DISPERSIONS OF THYROTROPIC AND MAMMOTROPIC TUMORS.
    Endocrinology, 1964, Volume: 75

    Topics: Animals; Beta-Globulins; Blood; Electrophoresis; Iodine Isotopes; Mammary Neoplasms, Animal; Mammary

1964
METABOLISM OF LABELLED THYROID HORMONE BY THYROTROPIC AND ADRENOTROPIC MOUSE PITUITARY TUMORS.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Animals; Autoradiography; Chromatography; Iodine Isotopes; Kidney; Mammary Neoplasms, Animal; Mammar

1964
Growth inhibitory effects of thyroid hormones on androgen-dependent mammary tumor cells.
    Journal of steroid biochemistry, 1981, Volume: 15

    Topics: Androgens; Animals; Cell Division; Cells, Cultured; Female; Mammary Neoplasms, Experimental; Mice; N

1981
Nuclear thyroid hormone receptors, alpha-glycerophosphate dehydrogenases, and malic enzyme in N-nitrosomethylurea-induced rat mammary tumors.
    Cancer research, 1983, Volume: 43, Issue:7

    Topics: Animals; Binding, Competitive; Cell Nucleus; Cytosol; Female; Glycerolphosphate Dehydrogenase; Liver

1983
Effects of hypothyroidism on the induction and growth of mammary cancer induced by 7,12-dimethylbenz(a)anthracene in the rat.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Female; Hypothyroidism; Mammary Neoplasms, E

1980
Hormonal and dietary regulation of hepatic enzymes in tumor-bearing rats.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: Alanine Transaminase; Animals; Glucokinase; Hexokinase; Histocytochemistry; Hydrocortisone; Liver; M

1983
Effects of hypothyroidism on development of nitrosomethylurea-induced tumors of the mammary gland, thyroid gland, and other tissues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:4

    Topics: Animals; Female; Hypothyroidism; Kidney Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental;

1982
Effect of thyroid status on development of spontaneous mammary tumors in primiparous C3H mice.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Female; Hyperthyroidism; Hypothyroidism; Mammary Neoplasms, Experimental; Mice; Mice, Inbre

1982
Effect of 3,5,3'-triiodo-L-thyronine on the incidence and growth kinetics of spontaneous mammary tumors in C3H/HeN mice.
    Cancer research, 1981, Volume: 41, Issue:12 Pt 1

    Topics: Animals; Cell Division; Cocarcinogenesis; Female; Hyperplasia; Mammary Neoplasms, Experimental; Mice

1981
Effect of triiodothyronine and reserpine on induction and growth of mammary tumors in rats by 3-methylcholanthrene.
    Journal of surgical oncology, 1980, Volume: 14, Issue:3

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Methylcholanthrene; Rats; Reserpine; Time Factors;

1980
Inhibitory effects of potassium thiocyanate on normal and neoplastic mammary development in female mice.
    European journal of cancer, 1980, Volume: 16, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Female; Mammary Glands, Animal; Mammary Neoplasms, Experi

1980
Thyroid hormone inhibits androgen-enhanced DNA synthesis in Shionogi carcinoma 115 cells without affecting autocrine growth factor mRNA expression.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 50, Issue:1-2

    Topics: Animals; DNA, Neoplasm; Drug Synergism; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Growt

1994
Regulation of cytochromes P450 by DHEA and its anticarcinogenic action.
    Annals of the New York Academy of Sciences, 1995, Dec-29, Volume: 774

    Topics: Animals; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Indu

1995
Effects of altered thyroid states on mammary tumor growth and pituitary gland function in rats.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:3

    Topics: Animals; DNA, Neoplasm; Female; Growth Hormone; Hyperthyroidism; Hypothyroidism; In Vitro Techniques

1977
Effects of thyroid hormone on androgen- or basic fibroblast growth factor-induced proliferation of Shionogi carcinoma 115 mouse mammary carcinoma cells in serum-free culture.
    Cancer research, 1991, Aug-15, Volume: 51, Issue:16

    Topics: Animals; Base Sequence; Cell Division; Cell Line; Chloramphenicol O-Acetyltransferase; DNA Replicati

1991
Influence of L-thyroxine, L-triiodothyronine, thyroid stimulating hormone, or estradiol on the cell kinetics of cultured mammary cancer cells.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1989, Volume: 25, Issue:7

    Topics: Animals; Breast Neoplasms; Cell Cycle; Drug Interactions; Estradiol; Humans; Interphase; Kinetics; M

1989
3,5,3'-Triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) synthesis in rats hosting the R3230AC mammary tumour.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1986, Volume: 7, Issue:2-3

    Topics: Adenocarcinoma; Animals; Kidney; Liver; Mammary Neoplasms, Experimental; Rats; Rats, Inbred F344; Tr

1986
Preliminary survey of hormonal influences on multicellular architecture in primary cultures of mammary carcinoma cells.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:3

    Topics: Aldosterone; Animals; Cell Differentiation; Cells, Cultured; Corticosterone; Culture Media; Desoxyco

1974
Oxygen and L-triiodothyronine in radiotherapy of mouse tumors.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1968, Volume: 102, Issue:1

    Topics: Animals; Carbon Dioxide; Hyperbaric Oxygenation; Mammary Neoplasms, Experimental; Mice; Oxygen; Trii

1968