triiodothyronine has been researched along with Experimental Hepatoma in 46 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " 44 (generation time, 6 mo) was inhibited after the induction of hypothyroidism by Propylthiouracil (PTU) (0." | 3.66 | Inhibition of the growth of Morris hepatoma No. 44 in rats after induction of hypothyroidism: evidence that Morris hepatomas are thyroid dependent. ( Mishkin, S; Morris, HP; Murthy, PV; Yalovsky, MA, 1979) |
| "The growth rates of the transplantable Morris hepatomas 7777 and 5123tc are shown to be retarded in the surgically thyroidectomized-parathyroidectomized rat." | 1.26 | Involvement of the lodothyronines in liver and hepatoma cell proliferation in the rat. ( Kibert, L; Klein, K; Ove, P; Short, J, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (58.70) | 18.7374 |
| 1990's | 12 (26.09) | 18.2507 |
| 2000's | 4 (8.70) | 29.6817 |
| 2010's | 3 (6.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chi, HC | 1 |
| Chen, SL | 1 |
| Lin, SL | 1 |
| Tsai, CY | 1 |
| Chuang, WY | 1 |
| Lin, YH | 1 |
| Huang, YH | 1 |
| Tsai, MM | 1 |
| Yeh, CT | 1 |
| Lin, KH | 1 |
| Schmohl, KA | 1 |
| Müller, AM | 1 |
| Wechselberger, A | 1 |
| Rühland, S | 1 |
| Salb, N | 1 |
| Schwenk, N | 1 |
| Heuer, H | 1 |
| Carlsen, J | 1 |
| Göke, B | 1 |
| Nelson, PJ | 1 |
| Spitzweg, C | 1 |
| Perra, A | 4 |
| Kowalik, MA | 2 |
| Pibiri, M | 3 |
| Ledda-Columbano, GM | 4 |
| Columbano, A | 4 |
| Leoni, VP | 1 |
| Saliba, C | 1 |
| Grober, OM | 1 |
| Ravo, M | 1 |
| Weisz, A | 1 |
| Locker, J | 1 |
| Ghiso, E | 1 |
| Giordano, S | 1 |
| Hemmings, SJ | 1 |
| Strickland, J | 1 |
| Rivlin, RS | 1 |
| Osnos, M | 1 |
| Hornibrook, R | 1 |
| Motwani, NM | 1 |
| Unakar, NJ | 1 |
| Roy, AK | 1 |
| Widman, LE | 1 |
| Chasin, LA | 1 |
| Francavilla, A | 1 |
| Ove, P | 3 |
| Van Thiel, DH | 1 |
| Coetzee, ML | 2 |
| Wu, SK | 1 |
| DiLeo, A | 1 |
| Starzl, TE | 1 |
| Presta, M | 1 |
| Zavanella, T | 1 |
| Mazzocchi, C | 1 |
| Ziliani, S | 1 |
| Mazzoleni, G | 1 |
| Calovini, D | 1 |
| Braga, M | 1 |
| Ragnotti, G | 1 |
| Sato, K | 4 |
| Robbins, J | 8 |
| Sorimachi, K | 8 |
| Niwa, A | 2 |
| Yasumura, Y | 2 |
| Sekura, RD | 1 |
| Cahnmann, HJ | 1 |
| Jakoby, WB | 1 |
| Short, J | 2 |
| Klein, K | 2 |
| Solomon, DH | 1 |
| Mishkin, S | 2 |
| Lemaire, M | 1 |
| Baeyens, W | 1 |
| de Saint-Georges, L | 1 |
| Baugnet-Mahieu, L | 1 |
| Kibert, L | 1 |
| Wan, YJ | 1 |
| Wang, L | 1 |
| Wu, TC | 1 |
| Ming, M | 1 |
| Sikstrom, R | 1 |
| Lachance, S | 1 |
| Delalandre, A | 1 |
| Carrière, S | 1 |
| Chan, JS | 1 |
| Chalmers, DK | 1 |
| Scholz, GH | 2 |
| Topliss, DJ | 3 |
| Kolliniatis, E | 3 |
| Munro, SL | 1 |
| Craik, DJ | 1 |
| Iskander, MN | 1 |
| Stockigt, JR | 3 |
| Barlow, JW | 2 |
| Ribeiro, RC | 3 |
| Cavalieri, RR | 3 |
| Lomri, N | 3 |
| Rahmaoui, CM | 1 |
| Baxter, JD | 3 |
| Scharschmidt, BF | 3 |
| Simeoni, LA | 2 |
| Park, SW | 1 |
| Piga, R | 1 |
| Loi, R | 2 |
| Shinozuka, H | 2 |
| Neves, FA | 1 |
| Gardner, DG | 1 |
| Morris, HP | 1 |
| Yalovsky, MA | 1 |
| Murthy, PV | 1 |
| Ohtani, R | 1 |
| Yayama, K | 1 |
| Takano, M | 1 |
| Itoh, N | 1 |
| Okamoto, H | 1 |
| Van Itallie, CM | 1 |
| Lakshmanan, M | 1 |
| Goncalves, E | 1 |
| Pontecorvi, A | 1 |
| Hashizume, K | 1 |
| Suzuki, S | 1 |
| Ichikawa, K | 1 |
| Takeda, T | 1 |
| Kobayashi, M | 1 |
| Muñoz, A | 1 |
| Höppner, W | 1 |
| Sap, J | 1 |
| Brady, G | 1 |
| Nordström, K | 1 |
| Seitz, HJ | 1 |
| Vennström, B | 1 |
| Nakabayashi, H | 1 |
| Taketa, K | 1 |
| Yamane, T | 1 |
| Oda, M | 1 |
| Sato, J | 1 |
| Inoue, A | 1 |
| Yamamoto, N | 1 |
| Morisawa, Y | 1 |
| Uchimoto, T | 1 |
| Yukioka, M | 1 |
| Morisawa, S | 1 |
| Lim, CF | 1 |
| Mitsuhashi, T | 1 |
| Uchimura, H | 1 |
| Takaku, F | 1 |
| Chang, E | 1 |
| Perlman, AJ | 1 |
| Rao, KM | 1 |
| Betschart, JM | 1 |
| Virji, MA | 1 |
1 review available for triiodothyronine and Experimental Hepatoma
| Article | Year |
|---|---|
Thyroid hormone metabolism in cultured hepatocytes.
Topics: Animals; Cells, Cultured; Glucose; Glutathione; Humans; Insulin; Iodine; Kinetics; Liver; Liver Neop | 1981 |
45 other studies available for triiodothyronine and Experimental Hepatoma
| Article | Year |
|---|---|
Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.
Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Hepatocytes; Humans; L | 2017 |
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentia | 2015 |
Thyroid hormone receptor ligands induce regression of rat preneoplastic liver lesions causing their reversion to a differentiated phenotype.
Topics: Animals; Apoptosis; Cell Differentiation; Choline Deficiency; Diethylnitrosamine; Glutathione Transf | 2009 |
Expression of c-jun is not mandatory for mouse hepatocyte proliferation induced by two nuclear receptor ligands: TCPOBOP and T3.
Topics: Animals; Cell Cycle Checkpoints; Cell Proliferation; Cell Transformation, Neoplastic; Constitutive A | 2011 |
Administration of diethylnitrosamine in the immediate postnatal period coupled with exposure to a choline deficient diet accelerates hepatocarcinogenesis in the rat.
Topics: Alanine Transaminase; Animals; Animals, Newborn; Blood Glucose; Choline Deficiency; Cocarcinogenesis | 2002 |
Effects of thyroid hormones upon flavin adenine dinucleotide pyrophosphorylase activity in Novikoff hepatoma in rats.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Flavin-Adenine Dinucleotide; Liver; Li | 1980 |
Multiple hormone requirement for the synthesis of alpha 2u-globulin by monolayers of rat hepatocytes in long term primary culture.
Topics: Alpha-Globulins; Animals; Cells, Cultured; Dexamethasone; Dihydrotestosterone; Female; Glycoproteins | 1980 |
Multihormonal induction of alpha 2u-globulin in an established rat hepatoma cell line.
Topics: Alpha-Globulins; Animals; Blood; Cattle; Cell Line; Clone Cells; Dexamethasone; Dihydrotestosterone; | 1982 |
Induction of hepatocyte stimulating activity by T3 and appearance of the activity despite inhibition of DNA synthesis by adriamycin.
Topics: Animals; Cells, Cultured; DNA; DNA, Neoplasm; Doxorubicin; Hepatectomy; Interleukin-6; Liver; Liver | 1984 |
Thyroid and chemical hepatocarcinogenesis: further insights from the hepatocarcinogen ZAMI 1305.
Topics: Animals; Carcinogens; Female; Hyperplasia; Liver Neoplasms, Experimental; Male; Organ Size; Propanol | 1984 |
Thyroid hormone metabolism in cultured monkey hepatocarcinoma cells. Monodeiodination activity in relation to cell growth.
Topics: Animals; Cell Cycle; Cells, Cultured; Culture Media; Diiodothyronines; Dithiothreitol; Haplorhini; I | 1980 |
Phenolic ring deiodination in cultured rat hepatoma cells, and subcellular localization of deiodinases in cultured rat hepatoma, monkey hepatocarcinoma cells and normal rat liver homogenates.
Topics: Animals; Cell Compartmentation; Cell Line; Haplorhini; Hydrogen-Ion Concentration; Iodide Peroxidase | 1980 |
Inhibitory effect of unlabeled iodothyronines on the deiodination of labeled thyroid hormones by cultured hepatocarcinoma cells.
Topics: Animals; Cells, Cultured; Chromatography, Thin Layer; Haplorhini; Liver Neoplasms, Experimental; Thy | 1980 |
Sulfate transfer to thyroid hormones and their analogs by hepatic aryl sulfotransferases.
Topics: Animals; Arylsulfotransferase; Cell Line; Cytoplasm; Haplorhini; In Vitro Techniques; Liver; Liver N | 1981 |
Glutathione deficiency induced by cystine and/or methionine deprivation does not affect thyroid hormone deiodination in cultured rat hepatocytes and monkey hepatocarcinoma cells.
Topics: Animals; Cell Line; Cells, Cultured; Cystine; Glutathione; Haplorhini; Iodine Radioisotopes; Kinetic | 1981 |
Correlation of circulating levels of a serum protein with triiodothyronine levels and hepatoma growth.
Topics: Animals; Blood Proteins; Cell Division; Hepatectomy; Liver Neoplasms, Experimental; Male; Molecular | 1982 |
Tri-iodothyronine (T3) stimulates the growth of Morris hepatoma cells grown in culture.
Topics: Animals; Cell Division; Cell Line; Culture Media; Kinetics; Liver; Liver Neoplasms, Experimental; Ra | 1982 |
Thyroid influence on the growth of hepatoma HW-165 in Wistar rats.
Topics: Animals; Cell Division; Liver Neoplasms, Experimental; Male; Microscopy, Electron; Mitosis; Neoplasm | 1981 |
Involvement of the lodothyronines in liver and hepatoma cell proliferation in the rat.
Topics: Animals; DNA; DNA Replication; Female; Hepatectomy; Liver; Liver Neoplasms, Experimental; Liver Rege | 1980 |
Activation and inactivation of thyroxine by cultured rat hepatoma cells.
Topics: Animals; Cells, Cultured; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glucuronidase; I | 1980 |
Dexamethasone increases the expression of retinoid X receptor genes in rat hepatoma cell lines.
Topics: Animals; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, Drug; Estrogens; In | 1994 |
Hormonal regulation of expression of the angiotensinogen gene in cultured mouse hepatoma cells.
Topics: Actins; Angiotensinogen; Animals; Cell Line; Chloramphenicol O-Acetyltransferase; Cyclic AMP; Dexame | 1993 |
Thyroid hormone uptake by hepatocytes: structure-activity relationships of phenylanthranilic acids with inhibitory activity.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Flufenamic Acid; Liver; Liver Neoplasms, Experimen | 1993 |
Influence of calmodulin antagonists and calcium channel blockers on triiodothyronine uptake by rat hepatoma and myoblast cell lines.
Topics: Analysis of Variance; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calmodulin; Cell Line; Di | 1993 |
Thyroid hormone export regulates cellular hormone content and response.
Topics: Animals; Animals, Newborn; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; C | 1996 |
Thyroid hormone export in rat FRTL-5 thyroid cells and mouse NIH-3T3 cells is carrier-mediated, verapamil-sensitive, and stereospecific.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Tr | 1999 |
Cell proliferation induced by 3,3',5-triiodo-L-thyronine is associated with a reduction in the number of preneoplastic hepatic lesions.
Topics: Animals; Cell Division; Glutathione Transferase; Liver Neoplasms, Experimental; Male; Mitogens; Prec | 1999 |
Cell proliferation induced by triiodothyronine in rat liver is associated with nodule regression and reduction of hepatocellular carcinomas.
Topics: Animals; Anticarcinogenic Agents; Cell Division; Glutathione Transferase; Liver; Liver Neoplasms, Ex | 2000 |
Thyroid hormone export varies among primary cells and appears to differ from hormone uptake.
Topics: Animals; Calcium Channel Blockers; Chorion; Decidua; Female; Heart Ventricles; Humans; Indicators an | 2002 |
Phenolic and nonphenolic ring deiodinations of iodothyronines in cultured hepatocarcinoma cell homogenate from monkey.
Topics: Animals; Cations, Divalent; Cells, Cultured; Diiodothyronines; Dose-Response Relationship, Drug; Hap | 1979 |
Effects of propylthiouracil and methylmercaptoimidazol on metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells.
Topics: Animals; Cells, Cultured; Diiodothyronines; Haplorhini; Iodine; Liver Neoplasms, Experimental; Methi | 1979 |
Inhibition of the growth of Morris hepatoma No. 44 in rats after induction of hypothyroidism: evidence that Morris hepatomas are thyroid dependent.
Topics: Animals; Female; Hypothyroidism; Iodine Radioisotopes; Liver Neoplasms, Experimental; Male; Propylth | 1979 |
Uptake and metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells. Effects of potassium cyanide and dinitrophenol.
Topics: Animals; Biological Transport, Active; Cell Line; Cyanides; Dinitrophenols; Liver; Liver Neoplasms, | 1978 |
Stimulation of angiotensinogen production in primary cultures of rat hepatocytes by glucocorticoid, cyclic adenosine 3',5'-monophosphate, and interleukin-6.
Topics: Angiotensinogen; Animals; Bucladesine; Cells, Cultured; Colforsin; Cyclic AMP; Cytokines; Dexamethas | 1992 |
Thyroid hormone and dexamethasone increase the levels of a messenger ribonucleic acid for a mitochondrially encoded subunit but not for a nuclear-encoded subunit of cytochrome c oxidase.
Topics: Animals; Cell Nucleus; Cytochrome b Group; Dexamethasone; DNA, Mitochondrial; Electron Transport Com | 1990 |
Differential effect of a new thyromimetic on triiodothyronine transport into myoblasts and hepatoma and neuroblastoma cells.
Topics: Animals; Biological Transport; Humans; Kinetics; Liver Neoplasms, Experimental; Mice; Muscles; Neuro | 1992 |
Effect of active vitamin D3 on the levels of NADPH-dependent cytosolic 3,5,3'-triiodo-L-thyronine-binding protein.
Topics: Animals; Calcifediol; Calcitriol; Calcium; Carrier Proteins; Cell Line; Cytosol; Kidney; Kinetics; L | 1991 |
The chicken c-erbA alpha-product induces expression of thyroid hormone-responsive genes in 3,5,3'-triiodothyronine receptor-deficient rat hepatoma cells.
Topics: Animals; Base Sequence; Chickens; Cycloheximide; Gene Expression; Genes; Genomic Library; Liver Neop | 1990 |
Hormonal control of alpha-fetoprotein secretion in human hepatoma cell lines proliferating in chemically defined medium.
Topics: alpha-Fetoproteins; Animals; Cell Division; Cell Line; Cyclic AMP; Dexamethasone; Drug Interactions; | 1985 |
Unesterified long-chain fatty acids inhibit thyroid hormone binding to the nuclear receptor. Solubilized receptor and the receptor in cultured cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Fatty Acids, Nonesterified; Fatty Acids, Unsaturated; Kineti | 1989 |
Uptake of 3,5,3'-triiodothyronine by cultured rat hepatoma cells is inhibitable by nonbile acid cholephils, diphenylhydantoin, and nonsteroidal antiinflammatory drugs.
Topics: Aminoisobutyric Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell | 1989 |
n-Butyrate increases the level of thyroid hormone nuclear receptor in non-pituitary cultured cells.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Dexamethasone; Dose-Response | 1987 |
Multiple hormones regulate angiotensinogen messenger ribonucleic acid levels in a rat hepatoma cell line.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensinogen; Animals; Cell Line; Dexamethasone; Estradiol; | 1987 |
Hormone-induced actin polymerization in rat hepatoma cells and human leucocytes.
Topics: Actins; Animals; Glucagon; Hormones; Humans; In Vitro Techniques; Insulin; Isoproterenol; Liver Neop | 1985 |
Effects of cycloheximide on inverse regulation of phenolic and nonphenolic ring deiodinases in monkey hepatocarcinoma cells.
Topics: Animals; Cells, Cultured; Culture Media; Cycloheximide; Dactinomycin; Haplorhini; Iodide Peroxidase; | 1985 |