triiodothyronine has been researched along with Exophthalmos in 39 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Exophthalmos: Abnormal protrusion of both eyes; may be caused by endocrine gland malfunction, malignancy, injury, or paralysis of the extrinsic muscles of the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Demonstration of LATS in the serum, slightly increased serum-triiodothyronine-levels, failure of normal response to TRH and an abnormal triiodothyronine-suppression test in euthyroid ophthalmopathy may herald the manifestation of hyperthyroidism at some later time." | 3.65 | Euthyroid endocrine ophthalmopathy: a study of the pituitary-thyroid system. ( Földes, J, 1975) |
| "The degree of amelioration of diplopia did not significantly differ between the two groups (P = 0." | 2.70 | Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized study. ( Barbesino, G; Bartalena, L; Bartolomei, MP; Cartei, F; Dell'Unto, E; Lepri, P; Manetti, L; Marcocci, C; Mazzi, B; Nardi, M; Pinchera, A; Rocchi, R; Tanda, ML, 2001) |
| "Incidence of the hyperthyroidism is continuously increasing, whereas our knowledge concerning the facilitating or etiologic factors of this increase are still partial." | 1.33 | HLA class II distribution in Congolese with hyperthyroidism: preliminary results. ( Bidingija, M; Buzzetti, R; Ditu, M; Galgani, A, 2006) |
| "We examined 13 patients with euthyroid Graves' disease suspected ophthalmologically, by comparing them with 20 patients with untreated Graves' disease and by following them up for 5 to 10 years." | 1.29 | Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease. ( Amino, N; Asahi, K; Hidaka, Y; Iwatani, Y; Kashiwai, T; Tada, H; Tamaki, H, 1995) |
| "We also studied various types of exophthalmos: 31 cases of endocrine exophthalmos, whether the thyroidal plasma values were normal or not, and 2 cases of exophthalmia with expansive orbital hyperplasia in which there had been no previous thyroidal disturbance." | 1.27 | [Importance of the assay of T3 and T4 tears and plasma for the diagnosis of endocrine exophthalmos]. ( Glomaud, J; Liotet, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (84.62) | 18.7374 |
| 1990's | 1 (2.56) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 1 (2.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Machen, L | 1 |
| MacIntosh, P | 1 |
| LANGFORD, HG | 1 |
| GREER, MA | 1 |
| CHAVEZ MONTES, J | 1 |
| WESTPHAL, OR | 1 |
| DOBYNS, BM | 1 |
| WRIGHT, A | 1 |
| SANDERS, MA | 1 |
| GOROWSKI, T | 1 |
| HADDAD, H | 1 |
| LEVIN, ME | 1 |
| WATTS, WE | 1 |
| BEKAERT, S | 1 |
| LELONG, M | 1 |
| CANLORBE, P | 1 |
| JOB, JC | 1 |
| SCHAISON, G | 1 |
| TORIBE, H | 1 |
| SCHIRMER, KE | 1 |
| Gruñeiro-Papendieck, L | 1 |
| Chiesa, A | 1 |
| Finkielstain, G | 1 |
| Heinrich, JJ | 1 |
| Bidingija, M | 1 |
| Galgani, A | 1 |
| Buzzetti, R | 1 |
| Ditu, M | 1 |
| Otter, R | 1 |
| Wiersinga, WM | 1 |
| Peeters, HF | 1 |
| Bleeker, GM | 1 |
| Touber, JL | 1 |
| Feldt-Rasmussen, U | 1 |
| Kemp, A | 1 |
| Bech, K | 1 |
| Madsen, SN | 1 |
| Date, J | 1 |
| Kashiwai, T | 1 |
| Tada, H | 1 |
| Asahi, K | 1 |
| Hidaka, Y | 1 |
| Tamaki, H | 1 |
| Iwatani, Y | 1 |
| Amino, N | 1 |
| Kubo, T | 1 |
| Toki, J | 1 |
| Kado, Y | 1 |
| Kurihara, M | 1 |
| Moriwake, T | 1 |
| Kanzaki, S | 1 |
| Seino, Y | 1 |
| Marcocci, C | 1 |
| Bartalena, L | 1 |
| Tanda, ML | 1 |
| Manetti, L | 1 |
| Dell'Unto, E | 1 |
| Rocchi, R | 1 |
| Barbesino, G | 1 |
| Mazzi, B | 1 |
| Bartolomei, MP | 1 |
| Lepri, P | 1 |
| Cartei, F | 1 |
| Nardi, M | 1 |
| Pinchera, A | 1 |
| Bürgi, H | 1 |
| Kaplan, HJ | 1 |
| Földes, J | 1 |
| Kahaly, G | 1 |
| Yuan, JP | 1 |
| Krause, U | 1 |
| Hülbusch, K | 1 |
| Beyer, J | 1 |
| Glomaud, J | 1 |
| Liotet, S | 1 |
| Lynch, PJ | 1 |
| Maize, JC | 1 |
| Sisson, JC | 1 |
| Hesch, RD | 1 |
| Huefner, M | 1 |
| Emrich, D | 1 |
| Klein, E | 2 |
| Soumar, J | 1 |
| Bednár, J | 1 |
| Strasek, J | 1 |
| Mahaux, JE | 1 |
| Chamla-Soumenkoff, J | 1 |
| Delcourt, R | 1 |
| Nagel, N | 1 |
| Levin, S | 1 |
| Lehr, HJ | 1 |
| Werner, H | 1 |
| Rudorff, KH | 1 |
| Herrmann, J | 1 |
| Höschl, R | 1 |
| Gimlette, TM | 1 |
| Sakurada, T | 1 |
| Saito, S | 1 |
| Yamaguchi, T | 1 |
| Yoshida, K | 1 |
| Yamamoto, M | 1 |
| Anderson, DR | 1 |
| Friis, T | 1 |
| Horster, FA | 1 |
| Reinwein, D | 1 |
| Valenti, G | 2 |
| Cordella, M | 2 |
| Wyse, EP | 1 |
| McConahey, WM | 1 |
| Woolner, LB | 1 |
| Scholz, DA | 1 |
| Kearns, TP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Efficacy and Safety of Intravenous Pulsed Methylprednisolone and Oral Methotrexate Versus Intravenous Pulsed Methylprednisolone and Oral Placebo in the Treatment of Active Moderate and Severe Thyroid Eye Disease - a Prospective, Randomized, [NCT00348413] | 80 participants (Anticipated) | Interventional | 2003-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for triiodothyronine and Exophthalmos
| Article | Year |
|---|---|
Endocrine exophthalmos: an immunologic aberration.
Topics: Autoantibodies; Exophthalmos; Graves Disease; Humans; Immunity; Immunity, Cellular; Immunoglobulin G | 1977 |
[Results of the thyroid gland function diagnosis with radioiodine in hyperthyroidism and endocrine ophthalmopathies].
Topics: Exophthalmos; Eye Diseases; Humans; Hyperthyroidism; Iodine Radioisotopes; Protein Binding; Radionuc | 1965 |
Mechanisms of Graves' disease and endocrine exophthalmos.
Topics: Animals; Binding Sites; Biological Assay; Exophthalmos; Fishes; Graves Disease; Humans; Hyperthyroid | 1969 |
1 trial available for triiodothyronine and Exophthalmos
| Article | Year |
|---|---|
Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized study.
Topics: Administration, Oral; Bone Density; Combined Modality Therapy; Diplopia; Exophthalmos; Eyelids; Fema | 2001 |
35 other studies available for triiodothyronine and Exophthalmos
| Article | Year |
|---|---|
Considerations in Pediatric Proptosis.
Topics: Adolescent; Antithyroid Agents; Blepharoptosis; Cholinesterase Inhibitors; Drug Therapy, Combination | 2018 |
Production of exophthalmos in Fundulus heteroclitus (var. Bermudae) by triiodothyronine and desiccated thyroid.
Topics: Animals; Exophthalmos; Fundulidae; Humans; Thyroid (USP); Thyroid Gland; Thyroid Hormones; Triiodoth | 1957 |
Exophthalmos and localized pretibial myxedema in a euthyroid patient; studies with triiodothyronine.
Topics: Exophthalmos; Humans; Medical Records; Myxedema; Triiodothyronine | 1957 |
[Basedow's exophthalmos; a new therapeutic technic].
Topics: Aged; Exophthalmos; Hyperthyroidism; Triiodothyronine | 1958 |
[Treatment of malignant exophthalmos by roentgen irradiation in combination with triiodothyronine or prednisone].
Topics: Exophthalmos; Pituitary Gland; Pituitary Irradiation; Prednisone; Triiodothyronine | 1961 |
A question on the exophthalmos-producing quality of triiodothyronine.
Topics: Exophthalmos; Humans; Triiodothyronine | 1962 |
[Acute exophthalmos after thyroidectomy treated with triiodothyronine and prednisone].
Topics: Exophthalmos; Humans; Parathyroid Glands; Prednisone; Thyroid Gland; Thyroidectomy; Triiodothyronine | 1961 |
Failure of a new TSH inhibitor, the methyl ether of triiodothyrepropionic acid, in the treatment of endocrine exophthalmos.
Topics: Exophthalmos; Goiter; Graves Disease; Humans; Methyl Ethers; Thyrotropin; Thyrotropin-Releasing Horm | 1963 |
LOCALIZED MYXEDEMA--GENERALIZED IN SCARS.
Topics: Cicatrix; Dexamethasone; Diuretics; Exophthalmos; Goiter; Graves Disease; Humans; Hydrochlorothiazid | 1964 |
[EXOPHTHALMOS].
Topics: Exophthalmos; Humans; Oculomotor Muscles; Physiology; Pituitary Hormones, Anterior; Reserpine; Sympa | 1964 |
[BASEDOW'S DISEASE AND JUVENILE AND INFANTILE HYPERTHYROIDISM. CRITICAL STUDY APROPOS OF 5 CASES].
Topics: Adolescent; Bone and Bones; Child; Child Behavior Disorders; Congenital Abnormalities; Diagnosis; Ex | 1964 |
[EXPERIMENTAL STUDY ON EXOPHTHALMOS IN HYPERTHYROIDISM: STUDIES ON THE EXOPHTHALMOS-PRODUCING SUBSTANCE].
Topics: Biological Assay; Chromatography; Cornea; Exophthalmos; Fishes; Hyperthyroidism; Pharmacology; Pitui | 1964 |
Intercorneal diameter measurement for exophthalmos-producing factor.
Topics: Cornea; Exophthalmos; Thyroid (USP); Thyroid Gland; Thyrotropin; Triiodothyronine | 1962 |
Pediatric Graves' disease: outcome and treatment.
Topics: Adolescent; Antithyroid Agents; Body Height; Child; Child, Preschool; Decision Making; Exophthalmos; | 2003 |
HLA class II distribution in Congolese with hyperthyroidism: preliminary results.
Topics: Child; Democratic Republic of the Congo; Exophthalmos; Graves Disease; HLA-D Antigens; Humans; Hyper | 2006 |
[Experience with the thyrotropin releasing hormone (TRH) test in the diagnosis of Graves' ophthalmopathy].
Topics: Adult; Aged; Diagnosis, Differential; Exophthalmos; Female; Graves Disease; Humans; Male; Middle Age | 1982 |
Serum thyroglobulin, its autoantibody and thyroid stimulating antibodies in the endocrine exophthalmos.
Topics: Adult; Aged; Antibodies; Autoantibodies; Exophthalmos; Female; Graves Disease; Humans; Male; Middle | 1981 |
Significance of thyroid stimulating antibody and long term follow up in patients with euthyroid Graves' disease.
Topics: Adult; Aged; Exophthalmos; Eye Diseases; Female; Graves Disease; Humans; Immunoglobulins, Thyroid-St | 1995 |
Thyroid-stimulating antibody in a patient with euthyroid Graves' disease.
Topics: Antithyroid Agents; Autoantibodies; Child; Exophthalmos; Female; Graves Disease; Humans; Immunoglobu | 2000 |
[Pathophysiology of the thyroid gland. Some newer aspects (author's transl)].
Topics: Binding, Competitive; Exophthalmos; Graves Disease; Humans; Immunoglobulin G; Receptors, Cell Surfac | 1977 |
Euthyroid endocrine ophthalmopathy: a study of the pituitary-thyroid system.
Topics: Exophthalmos; Humans; Hyperthyroidism; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thyrotrop | 1975 |
Ciclosporin and thyroid-stimulating immunoglobulins in endocrine orbitopathy.
Topics: Adult; Aged; Cyclic AMP; Cyclosporins; Exophthalmos; Female; Graves Disease; Humans; Immunoglobulin | 1989 |
[Importance of the assay of T3 and T4 tears and plasma for the diagnosis of endocrine exophthalmos].
Topics: Adult; Endocrine System Diseases; Exophthalmos; Female; Humans; Male; Middle Aged; Tears; Thyroxine; | 1987 |
Pretibial myxedema and nonthyrotoxic thyroid disease.
Topics: Adult; Autoantibodies; Autoimmune Diseases; Bone Diseases; Diabetes Complications; Exophthalmos; Fem | 1973 |
Triiodothyronine levels in patients with euthyroid endocrine exophthalmos and during treatment of thyrotoxicosis.
Topics: Adult; Antithyroid Agents; Exophthalmos; Humans; Hyperthyroidism; Iodine Radioisotopes; Middle Aged; | 1974 |
[Comparative values of protein-bound iodine, the in vitro thyroxine-binding protein capacity and blood cholesterol level in some diseases of the thyroid gland].
Topics: Adult; Aged; Antithyroid Agents; Blood Proteins; Cholesterol; Dexamethasone; Exophthalmos; Female; H | 1967 |
The effect of triiodothyronine on cervical lymphoid structures, thyroid activity, IgG and IgM immunoglobulin level and exophthalmos in Graves' disease.
Topics: Exophthalmos; Graves Disease; Humans; Immunoglobulin G; Immunoglobulin M; Long-Acting Thyroid Stimul | 1969 |
[T3-thyrotoxicosis in a 3-year-old girl (author's transl)].
Topics: Age Determination by Skeleton; Bone Development; Child, Preschool; Diarrhea; Exophthalmos; Female; G | 1974 |
A comparison of serum thyroxine (T 4 (D)), RT 3 U ratio and T 4 -RT 3 index with radioiodine uptake in the triiodothyronine suppression test.
Topics: Exophthalmos; Factor Analysis, Statistical; Humans; Hyperthyroidism; Iodine Radioisotopes; Thyroid F | 1972 |
The changes of serum triiodothyronine, thyroxine and thyroid stimulating hormone in two cases of hypothyroidism with unusual complications.
Topics: Child; Deafness; Exophthalmos; Goiter; Humans; Hypothyroidism; Male; Middle Aged; Myxedema; Radioimm | 1974 |
Long-acting thyroid stimulator (LATS) in hyperthyroidism and exophthalmos.
Topics: Adult; Aged; Animals; Exophthalmos; Female; Guinea Pigs; Humans; Hyperthyroidism; Iodine Isotopes; L | 1969 |
[On drug therapy of endocrine ophthalmopathy].
Topics: Edema; Exophthalmos; Eye Diseases; Eyelids; Humans; Long-Acting Thyroid Stimulator; Prednisone; Thyr | 1967 |
[On the effects of an adrenergic beta-blocking agent on experimental exophthalmos induced with triiodothyronine].
Topics: Animals; Exophthalmos; Female; Rats; Sympatholytics; Triiodothyronine | 1967 |
[Experimental exophthalmos caused by triiodothyronine, TSH and propylthiouracil after thymectomy].
Topics: Animals; Exophthalmos; Female; Propylthiouracil; Rats; Thymectomy; Thymus Gland; Thyroid Gland; Thyr | 1967 |
Ophthalmopathy without hyperthyroidism in patients with histologic Hashimoto's thyroiditis.
Topics: Adolescent; Adult; Autoantibodies; Basal Metabolism; Blood Proteins; Exophthalmos; Female; Hemagglut | 1968 |