triiodothyronine has been researched along with Encephalopathy, Toxic in 5 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neurotoxicity of iodine deficiency-induced hypothyroidism during developmental period results in serious impairments of brain function, such as learning and memory." | 7.79 | Neurotoxicity of developmental hypothyroxinemia and hypothyroidism in rats: Impairments of long-term potentiation are mediated by phosphatidylinositol 3-kinase signaling pathway. ( Chen, J; Dong, J; Min, H; Song, B; Teng, W; Wang, Y; Wei, W, 2013) |
| " Developmental hyperthyroidism was simulated by static waterborne exposure of zebrafish to varying concentrations (3-300 nM) of thyroxine (T4) or triiodothyronine (T3) beginning at 6 h post-fertilization (hpf) and continuing through 5 days post-fertilization (dpf)." | 3.91 | Changes in thyroid hormone activity disrupt photomotor behavior of larval zebrafish. ( Chen, X; Harvey, DJ; Lein, PJ; Miller, GW; Puschner, B; Walter, KM, 2019) |
| "Neurotoxicity of iodine deficiency-induced hypothyroidism during developmental period results in serious impairments of brain function, such as learning and memory." | 3.79 | Neurotoxicity of developmental hypothyroxinemia and hypothyroidism in rats: Impairments of long-term potentiation are mediated by phosphatidylinositol 3-kinase signaling pathway. ( Chen, J; Dong, J; Min, H; Song, B; Teng, W; Wang, Y; Wei, W, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walter, KM | 1 |
| Miller, GW | 1 |
| Chen, X | 1 |
| Harvey, DJ | 1 |
| Puschner, B | 1 |
| Lein, PJ | 1 |
| Wang, Y | 2 |
| Wei, W | 1 |
| Dong, J | 1 |
| Song, B | 1 |
| Min, H | 1 |
| Teng, W | 1 |
| Chen, J | 1 |
| Julvez, J | 1 |
| Debes, F | 1 |
| Weihe, P | 1 |
| Choi, AL | 1 |
| Grandjean, P | 1 |
| Blanco, J | 1 |
| Mulero, M | 1 |
| López, M | 1 |
| Domingo, JL | 1 |
| Sánchez, DJ | 1 |
| Sárközy, G | 1 |
| Griesmaier, E | 1 |
| He, X | 1 |
| Kapelari, K | 1 |
| Urbanek, M | 1 |
| Simbruner, G | 1 |
| Gressens, P | 1 |
| Keller, M | 1 |
5 other studies available for triiodothyronine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Changes in thyroid hormone activity disrupt photomotor behavior of larval zebrafish.
Topics: Animals; Antithyroid Agents; Embryo, Nonmammalian; Female; Hyperthyroidism; Hypothyroidism; Larva; M | 2019 |
Neurotoxicity of developmental hypothyroxinemia and hypothyroidism in rats: Impairments of long-term potentiation are mediated by phosphatidylinositol 3-kinase signaling pathway.
Topics: Animals; Antithyroid Agents; Blotting, Western; CA1 Region, Hippocampal; Diet; Electric Stimulation; | 2013 |
Thyroid dysfunction as a mediator of organochlorine neurotoxicity in preschool children.
Topics: Child, Preschool; Female; Humans; Hydrocarbons, Chlorinated; Hyperthyroidism; Hypothyroidism; Infant | 2011 |
BDE-99 deregulates BDNF, Bcl-2 and the mRNA expression of thyroid receptor isoforms in rat cerebellar granular neurons.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebellum; Down-Regulation; Halogenate | 2011 |
T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; Disease Models, Animal; Dose- | 2007 |