triiodothyronine has been researched along with Embryopathies in 34 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this report we describe a patient with Graves' disease diagnosed in early pregnancy and treated with propylthiouracil, which resulted in a large fetal goitre and fetal hypothyroidism." | 7.69 | In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil. ( Bos, AF; Derksen, JT; Rouwé, CW; Van Loon, AJ, 1995) |
| " The nonhalogenated thyroid hormone analog 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) was administered to pregnant ewes to determine if this compound could prevent cretinism in the thyroidectomized fetal lamb." | 7.66 | Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine. ( Bachrach, LK; Burrow, GN; Kent, G; Kudlow, JE; Silverberg, JD, 1982) |
| "Inadequately treated maternal hypothyroidism is associated with numerous adverse fetal and maternal outcomes." | 6.52 | Combination Levothyroxine + Liothyronine Treatment in Pregnancy. ( Foeller, ME; Silver, RM, 2015) |
| " Hypothyroidism in fetal sheep induced by removal of the thyroid gland caused asymmetric organ growth, increased pancreatic beta cell mass and proliferation, and was associated with increased circulating concentrations of insulin and leptin." | 3.85 | Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation. ( Anderson, M; Blache, D; Davenport, HM; Davis, MA; De Blasio, MJ; Forhead, AJ; Fowden, AL; Harris, SE; Kelly, AC; Limesand, SW; Meredith, D; Wooding, FBP, 2017) |
| "The diagnosis of fetal hypothyroidism is based at present on measurements of TSH and free thyroxine (FT4) in fetal blood samples obtained by cordocentesis." | 3.70 | Maternal compound W serial measurements for the management of fetal hypothyroidsm. ( Beck-Peccoz, P; Cortelazzi, D; Fisher, DA; Morpurgo, PS; Wu, SY; Zamperini, P, 1999) |
| " In this report we describe a patient with Graves' disease diagnosed in early pregnancy and treated with propylthiouracil, which resulted in a large fetal goitre and fetal hypothyroidism." | 3.69 | In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil. ( Bos, AF; Derksen, JT; Rouwé, CW; Van Loon, AJ, 1995) |
| "We compared fetal and maternal serum indexes of thyroid status at delivery in 70 patients with Graves' disease who required therapy with thionamides (such as propylthiouracil) during pregnancy." | 3.67 | Antithyroid drug therapy for Graves' disease during pregnancy. Optimal regimen for fetal thyroid status. ( Ishikawa, N; Ito, K; Momotani, N; Noh, J; Oyanagi, H, 1986) |
| " The nonhalogenated thyroid hormone analog 3,5-dimethyl-3'-isopropyl-L-thyronine (DIMIT) was administered to pregnant ewes to determine if this compound could prevent cretinism in the thyroidectomized fetal lamb." | 3.66 | Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine. ( Bachrach, LK; Burrow, GN; Kent, G; Kudlow, JE; Silverberg, JD, 1982) |
| "The assessment of fetal thyroid function by measurement of reverse triiodothyronine (RT3) in amniotic fluid (AF) seems to be a valuable diagnostic tool in detecting fetal hypothyroidism." | 3.66 | [Diagnostic possibilities of the function of the fetal thyroid gland by amniocentesis (author's transl)]. ( Cooreman, G; Etzrodt, A; Friedrich, E; Habedank, M, 1981) |
| " Because of the potential risk of fetal hypothyroidism, an amniocentesis, with an injection of 500 mug of thyroxine, was performed weekly from week 33 until delivery." | 3.65 | Intra-amniotic injection of thyroxine (T4Y to a human fetus. Evidence for conversion of T4 to reverse T3. ( Fismer, FA; Giles, H; Lightner, ES; Woolfenden, J, 1977) |
| "Inadequately treated maternal hypothyroidism is associated with numerous adverse fetal and maternal outcomes." | 2.52 | Combination Levothyroxine + Liothyronine Treatment in Pregnancy. ( Foeller, ME; Silver, RM, 2015) |
| "A maternal history of Graves' disease places the fetus at risk for thyrotoxicosis in utero via the placental transfer of thyroid-stimulating immunoglobulins." | 1.29 | Fetal thyrotoxicosis: a case report and recommendations for prediction, diagnosis, and treatment. ( Couch, R; Ginsberg, J; Wallace, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (55.88) | 18.7374 |
| 1990's | 8 (23.53) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 5 (14.71) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Camm, EJ | 1 |
| Inzani, I | 1 |
| De Blasio, MJ | 2 |
| Davies, KL | 1 |
| Lloyd, IR | 1 |
| Wooding, FBP | 2 |
| Blache, D | 2 |
| Fowden, AL | 2 |
| Forhead, AJ | 2 |
| Foeller, ME | 1 |
| Silver, RM | 1 |
| Ahmed, RG | 1 |
| Menut-Ruel, A | 1 |
| Barthod, M | 1 |
| Gauchez, AS | 1 |
| Dupuis, C | 1 |
| Charrie, A | 1 |
| Dubois, C | 1 |
| Leriche, A | 1 |
| Polverelli, JF | 1 |
| Althuser, M | 1 |
| Jouk, PS | 1 |
| Chabre, O | 1 |
| Harris, SE | 1 |
| Davis, MA | 1 |
| Kelly, AC | 1 |
| Davenport, HM | 1 |
| Meredith, D | 1 |
| Anderson, M | 1 |
| Limesand, SW | 1 |
| Groom, K | 1 |
| Snowise, S | 1 |
| Wheeler, B | 1 |
| Mekhail, A | 1 |
| Farrand, S | 1 |
| Parry, E | 1 |
| FISHER, DA | 5 |
| Ginter, EK | 1 |
| Koniukhov, BV | 1 |
| Bachrach, LK | 1 |
| Kudlow, JE | 1 |
| Silverberg, JD | 1 |
| Kent, G | 1 |
| Burrow, GN | 1 |
| Friedrich, E | 1 |
| Habedank, M | 1 |
| Cooreman, G | 1 |
| Etzrodt, A | 1 |
| El-Zaheri, MM | 1 |
| Vagenakis, AG | 1 |
| Hinerfeld, L | 1 |
| Emerson, CH | 1 |
| Braverman, LE | 2 |
| Wallace, C | 1 |
| Couch, R | 1 |
| Ginsberg, J | 1 |
| Wu, SY | 2 |
| Polk, DH | 1 |
| Huang, WS | 1 |
| Reviczky, A | 1 |
| Wang, K | 1 |
| Santini, F | 1 |
| Cortelazzi, D | 2 |
| Baggiani, AM | 1 |
| Marconi, AM | 1 |
| Beck-Peccoz, P | 3 |
| Chopra, IJ | 2 |
| Van Loon, AJ | 1 |
| Derksen, JT | 1 |
| Bos, AF | 1 |
| Rouwé, CW | 1 |
| Asteria, C | 1 |
| Rajanayagam, O | 1 |
| Collingwood, TN | 1 |
| Persani, L | 1 |
| Romoli, R | 1 |
| Mannavola, D | 1 |
| Zamperini, P | 2 |
| Buzi, F | 1 |
| Ciralli, F | 1 |
| Chatterjee, VK | 1 |
| Morpurgo, PS | 1 |
| Perrotin, F | 1 |
| Sembely-Taveau, C | 1 |
| Haddad, G | 1 |
| Lyonnais, C | 1 |
| Lansac, J | 1 |
| Body, G | 1 |
| Low, LC | 1 |
| Ratcliffe, WA | 1 |
| Alexander, WD | 1 |
| Filetti, S | 1 |
| Camus, M | 1 |
| Rodesch, F | 1 |
| Delange, F | 1 |
| Vigneri, R | 1 |
| Ermans, AM | 1 |
| Serup, J | 1 |
| Petersen, S | 1 |
| Lightner, ES | 1 |
| Fismer, FA | 1 |
| Giles, H | 1 |
| Woolfenden, J | 1 |
| Van Herle, AJ | 1 |
| Young, RT | 1 |
| Uller, RP | 1 |
| Brinkman, CR | 1 |
| Crandall, BF | 1 |
| Hollingsworth, DR | 2 |
| Belin, RP | 1 |
| Parker, JC | 1 |
| Moser, RJ | 1 |
| McKean, H | 1 |
| Horger, EO | 1 |
| Kenimer, JG | 1 |
| Azukizawa, M | 1 |
| Hershman, JM | 1 |
| Kansal, PC | 1 |
| Leaming, AB | 1 |
| Thorpe-Beeston, JG | 2 |
| Nicolaides, KH | 2 |
| Gosden, CM | 1 |
| McGregor, AM | 1 |
| Snijders, RJ | 1 |
| Felton, CV | 1 |
| Momotani, N | 1 |
| Noh, J | 1 |
| Oyanagi, H | 1 |
| Ishikawa, N | 1 |
| Ito, K | 1 |
| Robuschi, G | 1 |
| Emanuele, R | 1 |
| d'Amato, L | 1 |
| Gardini, E | 1 |
| Foscolo, MS | 1 |
| Gualerzi, C | 1 |
| Benassi, L | 1 |
| Gnudi, A | 1 |
| Roti, E | 1 |
| Austin, E | 1 |
| Goluboff, LG | 1 |
| Sisson, JC | 1 |
| Hamburger, JI | 1 |
| Morrison, JC | 1 |
| Boyd, M | 1 |
| Friedman, BI | 1 |
| Bucovaz, ET | 1 |
| Whybrew, WD | 1 |
| Koury, DN | 1 |
| Wiser, WL | 1 |
| Fish, SA | 1 |
1 review available for triiodothyronine and Embryopathies
| Article | Year |
|---|---|
Combination Levothyroxine + Liothyronine Treatment in Pregnancy.
Topics: Adult; Drug Therapy, Combination; Female; Fetal Diseases; Humans; Hypothyroidism; Maternal-Fetal Exc | 2015 |
33 other studies available for triiodothyronine and Embryopathies
| Article | Year |
|---|---|
Thyroid Hormone Deficiency Suppresses Fetal Pituitary-Adrenal Function Near Term: Implications for the Control of Fetal Maturation and Parturition.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenal Medulla; Adrenocorticotropic Hormone; Animals; Cell | 2021 |
Maternal bisphenol A alters fetal endocrine system: Thyroid adipokine dysfunction.
Topics: Adipokines; Administration, Oral; Animals; Benzhydryl Compounds; Endocrine System; Enzyme-Linked Imm | 2016 |
Fetal hypothyroidism induced by maternal anti-TSH receptor blocking antibodies and complicated by polyhydramnios despite the absence of goiter. Treatment by intra-amniotic injections of levothyroxine.
Topics: Adult; Amnion; Amniotic Fluid; Female; Fetal Diseases; Gestational Age; Humans; Hypothyroidism; Immu | 2017 |
Hypothyroidism in utero stimulates pancreatic beta cell proliferation and hyperinsulinaemia in the ovine fetus during late gestation.
Topics: Animals; Cell Proliferation; Cells, Cultured; Female; Fetal Diseases; Hyperinsulinism; Hypothyroidis | 2017 |
Maternal thyrotoxicosis and fetal goitre requiring in utero therapy for hypothyroidism and subsequent neonatal therapy for hyperthyroidism.
Topics: Antithyroid Agents; Carbimazole; Female; Fetal Diseases; Fetal Therapies; Goiter; Graves Disease; Hu | 2013 |
MANAGEMENT OF HYPOTHYROIDISM DURING INFANCY AND CHILDHOOD.
Topics: Adolescent; Alkaline Phosphatase; Antithyroid Agents; Body Height; Body Weight; Child; Cholesterol; | 1964 |
[The effect of triiodothyronine on the in vitro growth of the embryonic limb bones of mouse brachypodism-H and C57BL-61 mutant lines].
Topics: Animals; Bone Development; Bone Diseases, Developmental; Female; Fetal Diseases; In Vitro Techniques | 1966 |
Treatment of ovine cretinism in utero with 3,5-dimethyl-3'-isopropyl-L-thyronine.
Topics: Animals; Congenital Hypothyroidism; Dose-Response Relationship, Drug; Female; Fetal Diseases; Kineti | 1982 |
[Diagnostic possibilities of the function of the fetal thyroid gland by amniocentesis (author's transl)].
Topics: Amniocentesis; Amniotic Fluid; Female; Fetal Diseases; Fetus; Humans; Hypothyroidism; Pregnancy; Pre | 1981 |
Maternal thyroid function is the major determinant of amniotic fluid 3,3',5'-triiodothyronine in the rat.
Topics: Amniotic Fluid; Animals; Female; Fetal Diseases; Hypothyroidism; Pregnancy; Pregnancy Complications; | 1981 |
Fetal thyrotoxicosis: a case report and recommendations for prediction, diagnosis, and treatment.
Topics: Adult; Algorithms; Female; Fetal Diseases; Graves Disease; Heart Rate, Fetal; Humans; Pregnancy; Pre | 1995 |
Sulfate conjugates of iodothyronines in developing sheep: effect of fetal hypothyroidism.
Topics: Animals; Body Fluids; Fetal Diseases; Fetus; Hypothyroidism; Sheep; Sulfates; Thyroidectomy; Thyroni | 1993 |
A study of the serum 3,5,3'-triiodothyronine sulfate concentration in normal and hypothyroid fetuses at various gestational stages.
Topics: Embryonic and Fetal Development; Female; Fetal Diseases; Gestational Age; Humans; Hypothyroidism; Ma | 1993 |
In utero diagnosis and treatment of fetal goitrous hypothyroidism, caused by maternal use of propylthiouracil.
Topics: Adult; Dose-Response Relationship, Drug; Female; Fetal Diseases; Goiter; Graves Disease; Humans; Hyp | 1995 |
Prenatal diagnosis of thyroid hormone resistance.
Topics: Adult; DNA; Female; Fetal Blood; Fetal Diseases; Gestational Age; Heterozygote; Humans; Mutation; Pr | 1999 |
Maternal compound W serial measurements for the management of fetal hypothyroidsm.
Topics: Biomarkers; Cordocentesis; Diiodothyronines; Female; Fetal Blood; Fetal Diseases; Gestational Age; H | 1999 |
Prenatal diagnosis and early in utero management of fetal dyshormonogenetic goiter.
Topics: Adult; Amniocentesis; Amniotic Fluid; Cesarean Section, Repeat; Female; Fetal Blood; Fetal Diseases; | 2001 |
Intrauterine hypothyroidism due to antithyroid-drug therapy for thyrotoxicosis during pregnancy.
Topics: Carbimazole; Female; Fetal Diseases; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn; Mater | 1978 |
Decreased reverse triiodothyronine (RT3) concentration in amniotic fluid in fetal hypothyroidism.
Topics: Amniotic Fluid; Female; Fetal Diseases; Hypothyroidism; Pregnancy; Triiodothyronine | 1977 |
Hyperthyroidism during pregnancy treated with propylthiouracil. The significance of maternal and foetal parameters.
Topics: Adult; Female; Fetal Diseases; Fetal Heart; Heart Rate; Humans; Hyperthyroidism; Infant, Newborn; Lo | 1977 |
Intra-amniotic injection of thyroxine (T4Y to a human fetus. Evidence for conversion of T4 to reverse T3.
Topics: Adult; Amnion; Amniotic Fluid; Female; Fetal Diseases; Humans; Hypothyroidism; Infant, Newborn; Inje | 1977 |
Intra-uterine treatment of a hypothyroid fetus.
Topics: Adult; Female; Fetal Diseases; Humans; Hypothyroidism; Maternal-Fetal Exchange; Pregnancy; Pregnancy | 1975 |
Thyroid hormones and thyrotropin in amniotic fluid.
Topics: Amniotic Fluid; Female; Fetal Diseases; Gestational Age; Humans; Isomerism; Pregnancy; Prenatal Diag | 1975 |
Editorial: Reverse tri-iodothyronine and fetal thyroid status.
Topics: Amniotic Fluid; Animals; Female; Fetal Diseases; Humans; Hypothyroidism; Infant, Newborn; Isomerism; | 1975 |
Experimental cretinism in lambs: an intrauterine model with thyroid evaluation in surviving lambs.
Topics: Amniotic Fluid; Animals; Congenital Hypothyroidism; Disease Models, Animal; Female; Fetal Diseases; | 1975 |
Failure of triiodothyronine to prevent propylthiouracil-induced hypothyroidism and goiter in fetal sheep.
Topics: Animals; Disease Models, Animal; Female; Fetal Diseases; Goiter; Hypothyroidism; Organ Size; Pregnan | 1976 |
Thyroid function in fetuses with chromosomal abnormalities.
Topics: Chromosome Aberrations; Chromosome Disorders; Fetal Blood; Fetal Diseases; Gestational Age; Humans; | 1991 |
Thyroid function in anemic fetuses.
Topics: Anemia; Fetal Blood; Fetal Diseases; Gestational Age; Humans; Rh Isoimmunization; Thyroid Gland; Thy | 1990 |
Antithyroid drug therapy for Graves' disease during pregnancy. Optimal regimen for fetal thyroid status.
Topics: Antibodies; Antithyroid Agents; Female; Fetal Blood; Fetal Diseases; Fetus; Graves Disease; Humans; | 1986 |
Amniotic fluid thyrotropin (TSH) following maternal administration of thyrotropin releasing hormone.
Topics: Amniotic Fluid; Delivery, Obstetric; Female; Fetal Blood; Fetal Diseases; Humans; Hypothyroidism; In | 1985 |
Thyroxine derivatives in amniotic fluid. Fetal outcome in three patients with thyroid problems.
Topics: Adult; Amniocentesis; Amniotic Fluid; Female; Fetal Diseases; Graves Disease; Humans; Hypothyroidism | 1971 |
Hyperthyroidism associated with pregnancy.
Topics: Adolescent; Adult; Antithyroid Agents; Drug Therapy, Combination; Female; Fetal Diseases; Goiter; Hu | 1974 |
The effects of Renografin-60 on the fetal thyroid.
Topics: Amniotic Fluid; Birth Weight; Delivery, Obstetric; Diatrizoate; Female; Fetal Diseases; Goiter; Huma | 1973 |