triiodothyronine has been researched along with Elevated Cholesterol in 67 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this randomized controlled intervention, iodine-deficient, overweight or obese Moroccan women (n = 163) received 200 μg oral iodine or a placebo daily for 6 mo." | 9.20 | Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial. ( Aboussad, A; Chabaa, L; Cherkaoui, M; El Ansari, N; Herter-Aeberli, I; Rohner, R; Stinca, S; von Eckardstein, A; Zimmermann, MB, 2015) |
| "Various studies demonstrated a significant association between the trace element selenium (Se), hypercholesterolemia and the risk of cardiovascular disorders." | 7.73 | Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation. ( Bansal, MP; Dhingra, S, 2006) |
| "Cyclosporine may suppress transplant arteriosclerosis; however, it also raises plasma cholesterol, which could promote the disease." | 7.69 | Dose-dependent suppression of transplant arteriosclerosis in aorta-allografted, cholesterol-clamped rabbits. Suppression not eliminated by the cholesterol-raising effect of cyclosporine. ( Andersen, HO; Hansen, BF; Holm, P; Nordestgaard, BG; Stender, S, 1997) |
| "In this randomized controlled intervention, iodine-deficient, overweight or obese Moroccan women (n = 163) received 200 μg oral iodine or a placebo daily for 6 mo." | 5.20 | Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial. ( Aboussad, A; Chabaa, L; Cherkaoui, M; El Ansari, N; Herter-Aeberli, I; Rohner, R; Stinca, S; von Eckardstein, A; Zimmermann, MB, 2015) |
| "Controversy remains as to the risk of cardiovascular disease (CVD) associated with subclinical hypothyroidism (SCH), defined as an increased serum thyrotropin (TSH) concentration with normal free thyroxine and triiodothyronine levels." | 4.84 | Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence? ( Duntas, LH; Wartofsky, L, 2007) |
| "Various studies demonstrated a significant association between the trace element selenium (Se), hypercholesterolemia and the risk of cardiovascular disorders." | 3.73 | Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation. ( Bansal, MP; Dhingra, S, 2006) |
| "Cyclosporine may suppress transplant arteriosclerosis; however, it also raises plasma cholesterol, which could promote the disease." | 3.69 | Dose-dependent suppression of transplant arteriosclerosis in aorta-allografted, cholesterol-clamped rabbits. Suppression not eliminated by the cholesterol-raising effect of cyclosporine. ( Andersen, HO; Hansen, BF; Holm, P; Nordestgaard, BG; Stender, S, 1997) |
| " Four had unequivocal biochemical evidence of hypothyroidism-TSH greater than 34 mU/l and a low plasma thyroxine (T4) less than or equal to 45 nmol/l." | 3.67 | Thyroid dysfunction and hypercholesterolaemia in the general population of Glasgow, Scotland. ( Biggart, EM; O'Reilly, DS; Packard, CJ; Series, JJ; Shepherd, J, 1988) |
| "A thyroid hormone analogue, sodium dextro-triiodothyronine (NaDT3), at a dosage of 1 mg/day for 1 or 2 yr, decreased serum cholesterol levels about 30% in 26 hyperlipidemic adults." | 2.64 | Thyroid hormone-like effects without thyrotoxicosis during one year's therapy with NA-DT3 for hypercholesterolemia. ( Ahmad, U; Bowman, DH; Danowski, TS; Fisher, ER; Nolan, S; Stephan, T; Sunder, JH; Wingert, JP, 1976) |
| "Clinical hypothyroidism was prevalent (>20% of individuals studied) and was associated with cerebrovascular disease but not Alzheimer's disease-type neuropathology." | 1.48 | Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults. ( Brenowitz, WD; Han, F; Kukull, WA; Nelson, PT, 2018) |
| "These findings suggest that elevated cholesterol concentrations in the blood, especially against the background of suppressed thyroid function, can directly induce considerable damage to cardiomyocytes, intramural vessels, and erythrocytes without the development of myocardial ischemia and in the absence of atherosclerotic plaques." | 1.39 | Structural changes in the myocardium and serum lipid spectrum in experimental hypercholesterolemia and hypothyroidism. ( Klinnikova, MG; Lushnikova, EL; Molodykh, OP; Nepomnyashchikh, LM; Nepomnyashchikh, RD; Pichigin, VI; Polyakov, LP; Poteryaeva, ON; Russkikh, GS, 2013) |
| "Hypercholesterolemia is one of the most representative disorders of the common diseases." | 1.37 | Multi-center study on the prevalence of hypothyroidism in patients with hypercholesterolemia. ( Araki, R; Hata, S; Ise, T; Kimura, H; Miyazaki, Y; Naruse, M; Ogo, A; Ohtani, S; Saito, M; Sawamura, M; Shimatsu, A; Shimbo, T; Tagami, T; Tanaka, M; Tanaka, T; Yonezawa, K, 2011) |
| " Because of the low oral bioavailability of PA 22c, a series of prodrugs was synthesized and screened for oral efficacy in the CFR assay." | 1.35 | Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs. ( Boyer, SH; Cable, EE; Erion, MD; Fujitaki, JM; Godwin, JL; Hecker, SJ; Hou, J; Jacintho, JD; Jiang, H; Li, H; Li, W; Reddy, MV; Schulz, WG; Wu, R, 2008) |
| " Additional dose-response studies in hypercholesteremic rats confirmed the preferential effect of GC-1 on TRbeta-mediated parameters by showing a much higher potency to influence cholesterol and TSH than heart rate." | 1.31 | The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. ( Baxter, JD; Chiellini, G; Dillmann, WH; Gloss, B; Grover, GJ; Scanlan, TS; Swanson, E; Trost, SU; Volodarsky, T; Wang-Iverson, DB; Zhang, H, 2000) |
| "Treatment with CGS 23425 increased activity of the hepatic apo B-100 editosome, apobec-1." | 1.31 | Effects of a thyromimetic on apolipoprotein B-100 in rats. ( Dufresne, J; Hargrove, GM; Matsubara, S; Steele, RE; Stephan, ZF; Wada, Y; Wong, NC, 2000) |
| "Twenty-seven patients with primary hypothyroidism were studied to evaluate the relationship between hepatic function and thyroid hormone deficiency in this disorder." | 1.27 | Hepatic dysfunction in primary hypothyroidism. ( Naomi, S; Sato, T; Shimada, T; Tajiri, J; Umeda, T, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (47.76) | 18.7374 |
| 1990's | 7 (10.45) | 18.2507 |
| 2000's | 17 (25.37) | 29.6817 |
| 2010's | 10 (14.93) | 24.3611 |
| 2020's | 1 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Boyer, SH | 1 |
| Jiang, H | 1 |
| Jacintho, JD | 1 |
| Reddy, MV | 1 |
| Li, H | 1 |
| Li, W | 1 |
| Godwin, JL | 1 |
| Schulz, WG | 1 |
| Cable, EE | 1 |
| Hou, J | 1 |
| Wu, R | 1 |
| Fujitaki, JM | 1 |
| Hecker, SJ | 1 |
| Erion, MD | 1 |
| Sun, H | 1 |
| Zhu, W | 1 |
| Liu, J | 1 |
| An, Y | 1 |
| Wang, Y | 1 |
| Wang, G | 1 |
| Othman, RA | 1 |
| Myrie, SB | 1 |
| Mymin, D | 1 |
| Roullet, JB | 1 |
| DeBarber, AE | 1 |
| Steiner, RD | 1 |
| Jones, PJH | 1 |
| Brenowitz, WD | 1 |
| Han, F | 1 |
| Kukull, WA | 1 |
| Nelson, PT | 1 |
| Taub, R | 1 |
| Chiang, E | 1 |
| Chabot-Blanchet, M | 1 |
| Kelly, MJ | 1 |
| Reeves, RA | 1 |
| Guertin, MC | 1 |
| Tardif, JC | 1 |
| Nepomnyashchikh, LM | 1 |
| Lushnikova, EL | 1 |
| Polyakov, LP | 1 |
| Molodykh, OP | 1 |
| Klinnikova, MG | 1 |
| Russkikh, GS | 1 |
| Poteryaeva, ON | 1 |
| Nepomnyashchikh, RD | 1 |
| Pichigin, VI | 1 |
| Angelin, B | 3 |
| Kristensen, JD | 1 |
| Eriksson, M | 1 |
| Carlsson, B | 1 |
| Klein, I | 1 |
| Olsson, AG | 1 |
| Chester Ridgway, E | 1 |
| Ladenson, PW | 2 |
| Herter-Aeberli, I | 1 |
| Cherkaoui, M | 1 |
| El Ansari, N | 1 |
| Rohner, R | 1 |
| Stinca, S | 1 |
| Chabaa, L | 1 |
| von Eckardstein, A | 1 |
| Aboussad, A | 1 |
| Zimmermann, MB | 1 |
| Sharma, S | 1 |
| Dabla, PK | 1 |
| Kumar, M | 1 |
| Tagami, T | 1 |
| Kimura, H | 1 |
| Ohtani, S | 1 |
| Tanaka, T | 2 |
| Hata, S | 1 |
| Saito, M | 1 |
| Miyazaki, Y | 1 |
| Araki, R | 1 |
| Tanaka, M | 1 |
| Yonezawa, K | 1 |
| Sawamura, M | 1 |
| Ise, T | 1 |
| Ogo, A | 1 |
| Shimbo, T | 1 |
| Shimatsu, A | 1 |
| Naruse, M | 1 |
| Dhingra, S | 4 |
| Singh, U | 1 |
| Bansal, MP | 4 |
| Awaisheh, SS | 1 |
| Khalifeh, MS | 1 |
| Al-Ruwaili, MA | 1 |
| Khalil, OM | 1 |
| Al-Ameri, OH | 1 |
| Al-Groom, R | 1 |
| Auer, J | 1 |
| Weber, T | 1 |
| Eber, B | 1 |
| DELMEZ, JP | 1 |
| ENGEL, E | 1 |
| MACKAY, IR | 1 |
| GOBLE, AJ | 1 |
| SPARKES, F | 1 |
| ELLISON, T | 1 |
| GREENBERG, SM | 1 |
| LIN, TH | 1 |
| FRIIS, T | 3 |
| LINTRUP, J | 2 |
| NISSEN, NI | 3 |
| FURMAN, RH | 1 |
| HOWARD, RP | 1 |
| HAHNEMANN, S | 1 |
| REISEL, JH | 1 |
| DE GENNES, JL | 1 |
| TRUFFERT, J | 1 |
| ARTEAGA, A | 1 |
| DIAZ, F | 1 |
| TORRES, MC | 2 |
| NUNEZ, I | 2 |
| FELDMAN, EB | 1 |
| CARTER, AC | 1 |
| STRISOWER, EH | 1 |
| STRISOWER, B | 1 |
| ARTEAGALLONA, A | 1 |
| DIAZGREZ, F | 1 |
| JEPSON, EM | 1 |
| GODDEN, JD | 1 |
| GARNETT, ES | 1 |
| SCHWARZ, G | 1 |
| HUHNSTOCK, K | 1 |
| MECIANI, L | 1 |
| BRINA, A | 1 |
| HOLTEN, C | 1 |
| WATTS, RS | 1 |
| SCHOENFELD, RG | 1 |
| MINTZ, DO | 1 |
| BERENYI, MR | 1 |
| ROSENBERG, IN | 1 |
| KATZ, KH | 1 |
| NICHOLS, FL | 1 |
| Monteleone, P | 1 |
| Santonastaso, P | 1 |
| Pannuto, M | 1 |
| Favaro, A | 1 |
| Caregaro, L | 1 |
| Castaldo, E | 1 |
| Zanetti, T | 1 |
| Maj, M | 1 |
| Johansson, L | 1 |
| Rudling, M | 2 |
| Scanlan, TS | 2 |
| Lundåsen, T | 1 |
| Webb, P | 1 |
| Baxter, J | 1 |
| Parini, P | 1 |
| Jatwa, R | 1 |
| Kar, A | 1 |
| Sasaki, S | 1 |
| Kawai, K | 1 |
| Honjo, Y | 1 |
| Nakamura, H | 1 |
| Duntas, LH | 1 |
| Wartofsky, L | 1 |
| Winter, RJ | 1 |
| Green, OC | 1 |
| Tajiri, J | 1 |
| Shimada, T | 1 |
| Naomi, S | 1 |
| Umeda, T | 1 |
| Sato, T | 1 |
| Chastain, CB | 1 |
| DeMartino, GN | 1 |
| Goldberg, AL | 1 |
| Stephan, ZF | 2 |
| Yurachek, EC | 1 |
| Sharif, R | 1 |
| Wasvary, JM | 1 |
| Leonards, KS | 1 |
| Hu, CW | 1 |
| Hintze, TH | 1 |
| Steele, RE | 2 |
| Chen, WJ | 1 |
| Lin-Shiau, SY | 1 |
| Huang, HC | 1 |
| Lee, YT | 1 |
| Andersen, HO | 1 |
| Holm, P | 1 |
| Stender, S | 1 |
| Hansen, BF | 1 |
| Nordestgaard, BG | 1 |
| Taylor, AH | 1 |
| Nakamura, T | 1 |
| Wong, NC | 2 |
| De Lorenzo, F | 1 |
| Mukherjee, M | 1 |
| Kadziola, Z | 1 |
| Sherwood, R | 1 |
| Kakkar, VV | 1 |
| Friedl, KE | 1 |
| Moore, RJ | 1 |
| Hoyt, RW | 1 |
| Marchitelli, LJ | 1 |
| Martinez-Lopez, LE | 1 |
| Askew, EW | 1 |
| Trost, SU | 1 |
| Swanson, E | 1 |
| Gloss, B | 1 |
| Wang-Iverson, DB | 1 |
| Zhang, H | 1 |
| Volodarsky, T | 1 |
| Grover, GJ | 1 |
| Baxter, JD | 1 |
| Chiellini, G | 1 |
| Dillmann, WH | 1 |
| Gullberg, H | 1 |
| Forrest, D | 1 |
| Vennström, B | 1 |
| Wada, Y | 1 |
| Matsubara, S | 1 |
| Dufresne, J | 1 |
| Hargrove, GM | 1 |
| Sato, K | 1 |
| Agoh, H | 1 |
| Kaneshige, T | 1 |
| Hikasa, Y | 1 |
| Kagota, K | 1 |
| Lifshits, GI | 1 |
| Nikolaev, KIu | 1 |
| Oteva, EA | 1 |
| Nikolaeva, AA | 1 |
| Alaghband-Zadeh, J | 1 |
| Carter, GD | 1 |
| Daly, JR | 1 |
| Fowler, PB | 1 |
| Greenwood, TW | 1 |
| Gerok, W | 1 |
| Grossi, M | 1 |
| Blasi, N | 1 |
| Santori, L | 1 |
| Danowski, TS | 1 |
| Stephan, T | 1 |
| Nolan, S | 1 |
| Ahmad, U | 1 |
| Wingert, JP | 1 |
| Bowman, DH | 1 |
| Sunder, JH | 1 |
| Fisher, ER | 1 |
| Pallas, D | 1 |
| Koutras, DA | 1 |
| Adamopoulos, P | 1 |
| Marafelia, P | 1 |
| Souvatzoglou, A | 1 |
| Piperingos, G | 1 |
| Moulopoulos, SD | 1 |
| Ness, GC | 1 |
| Pendleton, LC | 1 |
| Li, YC | 1 |
| Chiang, JY | 1 |
| Series, JJ | 1 |
| Biggart, EM | 1 |
| O'Reilly, DS | 1 |
| Packard, CJ | 1 |
| Shepherd, J | 1 |
| Koschinsky, T | 1 |
| Gries, FA | 1 |
| Vogelberg, KH | 1 |
| Miss, H | 1 |
| Jahnke, K | 1 |
| Canzler, H | 1 |
| Horster, FA | 1 |
| Herrmann, J | 1 |
| Wildmeister, W | 1 |
| Krüskemper, HL | 1 |
| Kusakabe, T | 1 |
| Fujii, K | 1 |
| Fukase, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of Sterol Metabolism in Sitosterolemia: A Pilot Study of Patients Treated With Ezetimibe[NCT01584206] | 8 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| A Phase 1, Double-blind, Randomized, Placebo-controlled, First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food-effect of Single and Multiple Oral Doses of RJ4287 in Healthy Volunteers[NCT05921006] | Phase 1 | 98 participants (Anticipated) | Interventional | 2023-06-13 | Recruiting | ||
| Assessment of the Improvement of the Cardiovascular Risk Profile in Obese Women After Correction of Iodine Deficiency[NCT01985204] | 162 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery: a Randomized, Placebo Controlled Trial[NCT02734238] | Phase 4 | 53 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Height was measured using a stadiometer. Weight was measured using a calibrated digital scale. Body composition was determined using dual-energy X-ray absorptiometry. These data were used to calculate fat-free body mass, fat mass, and total body tissue mass. (NCT02734238)
Timeframe: end of each study phase: Day 11 for Phase 1, Day 39 for Phase 2, up to Day 85 for Phase 3
| Intervention | kilograms (Least Squares Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total Body Mass at end of Phase 1 | Total Body Mass at end of Phase 2 | Total Body Mass at end of Phase 3 | Fat-free Mass at end of Phase 1 | Fat-free Mass at end of Phase 2 | Fat-free Mass at end of Phase 3 | Fat Mass at end of Phase 1 | Fat Mass at end of Phase 2 | Fat Mass at end of Phase 3 | |
| Energy Deficit | 78.3 | 73.3 | 76.5 | 58.3 | 58.0 | 60.5 | 16.8 | 12.2 | 12.8 |
| Energy Deficit + Testosterone | 78.0 | 75.8 | 79.3 | 57.9 | 60.4 | 63.1 | 16.8 | 12.0 | 12.8 |
5 reviews available for triiodothyronine and Elevated Cholesterol
| Article | Year |
|---|---|
[Thyroid hormones and lipid metabolism].
Topics: Animals; Cholesterol, LDL; Drug Design; Humans; Hypercholesterolemia; Hypothyroidism; Lipid Metaboli | 2006 |
Cardiovascular risk and subclinical hypothyroidism: focus on lipids and new emerging risk factors. What is the evidence?
Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation Disorders; Cardiovascular Diseases; Humans; Hyperc | 2007 |
Canine hypothyroidism.
Topics: Alopecia; Animals; Dog Diseases; Dogs; Hypercholesterolemia; Hypothyroidism; Radioimmunoassay; Thyro | 1982 |
[Cell receptor defects as the cause of endocrine and metabolic diseases (author's transl)].
Topics: Adult; Binding Sites; Cell Membrane; Child; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type | 1979 |
[Thyroid hormone preparations].
Topics: Chemical Phenomena; Chemistry; Humans; Hypercholesterolemia; Thyroid Diseases; Thyroid Hormones; Thy | 1968 |
5 trials available for triiodothyronine and Elevated Cholesterol
| Article | Year |
|---|---|
Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe.
Topics: Adolescent; Adult; Anticholesteremic Agents; Cholestanol; Cholestenones; Cholesterol; Ezetimibe; Fem | 2017 |
Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-β agonist.
Topics: Adult; Body Mass Index; Cholesterol, LDL; Dose-Response Relationship, Drug; Double-Blind Method; Dru | 2013 |
Reductions in serum levels of LDL cholesterol, apolipoprotein B, triglycerides and lipoprotein(a) in hypercholesterolaemic patients treated with the liver-selective thyroid hormone receptor agonist eprotirome.
Topics: Anilides; Anticholesteremic Agents; Apolipoproteins B; Blood Pressure; Bone and Bones; Cholesterol, | 2015 |
Iodine Supplementation Decreases Hypercholesterolemia in Iodine-Deficient, Overweight Women: A Randomized Controlled Trial.
Topics: Administration, Oral; Adult; Blood Glucose; Body Mass Index; Cholesterol, HDL; Cholesterol, LDL; Die | 2015 |
Thyroid hormone-like effects without thyrotoxicosis during one year's therapy with NA-DT3 for hypercholesterolemia.
Topics: Adult; Aged; Bilirubin; Blood Cell Count; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Clinical | 1976 |
57 other studies available for triiodothyronine and Elevated Cholesterol
| Article | Year |
|---|---|
Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.
Topics: Animals; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Ev | 2008 |
Reduced Sensitivity to Thyroid Hormones Is Associated With High Remnant Cholesterol Levels in Chinese Euthyroid Adults.
Topics: Adult; Cholesterol; East Asian People; Female; Humans; Hypercholesterolemia; Male; Thyroid Function | 2022 |
Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Atherosclerosis; Cerebrovascular Disorders; Drug Combina | 2018 |
Structural changes in the myocardium and serum lipid spectrum in experimental hypercholesterolemia and hypothyroidism.
Topics: Animals; Atherosclerosis; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; | 2013 |
Evaluation of Thyroid Hormone Status in Children with Steroid Resistant Nephrotic Syndrome: A North India Study.
Topics: Asymptomatic Diseases; Child; Child, Preschool; Creatinine; Cross-Sectional Studies; Disease Progres | 2015 |
Thyroid hormone analogues: ready for prime time.
Topics: Atherosclerosis; Humans; Hypercholesterolemia; Ischemia; Neoplasms; Thyroid Hormones; Thyrotoxicosis | 2011 |
Multi-center study on the prevalence of hypothyroidism in patients with hypercholesterolemia.
Topics: Adult; Aged; Dyslipidemias; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Hypothyroidi | 2011 |
Protective role of selenium status on T3/T4 kinetics in rats under hyperlipidemia.
Topics: Animals; Cholesterol; Hypercholesterolemia; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Selen | 2003 |
Effect of supplementation of probiotics and phytosterols alone or in combination on serum and hepatic lipid profiles and thyroid hormones of hypercholesterolemic rats.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Dietary Supplements; Drug Therapy, Combination; Hypercho | 2013 |
Low triiodothyronine and cardiovascular disease.
Topics: Biomarkers; Comorbidity; Coronary Artery Disease; Cross-Sectional Studies; Follow-Up Studies; Humans | 2003 |
[Tests of l-triiodothyronine therapy of hypercholesteremia].
Topics: Cholesterol; Humans; Hypercholesterolemia; Triiodothyronine | 1957 |
The effect of triiodothyroacetate (triac) in hypercholesterolaemia.
Topics: Cholesterol; Humans; Hypercholesterolemia; Triiodothyronine | 1957 |
Comparative effects of D- and L-3,5,3'-triiodothyronine in chronic treatment of hypercholesteremic dogs.
Topics: Animals; Arteriosclerosis; Cholesterol; Dogs; Hypercholesterolemia; Inulin; Triiodothyronine | 1961 |
Effect of triiodothyropropionic acid (Triopron) on hypercholesterolaemia.
Topics: Hypercholesterolemia; Triiodothyronine | 1962 |
[Effects of triiodothyropropionic acid (triopron) in hypercholesterolemia].
Topics: Cholesterol; Hypercholesterolemia; Triiodothyronine | 1961 |
Effects of androsterone and triiodothyronine on serum lipids and lipoproteins, nitrogen balance and related metabolic phenomena in subjects with normal and decreased thyroid function, with hyperglyceridemia and/or hypercholesterolemia.
Topics: Androsterone; Cholesterol; Humans; Hypercholesterolemia; Hypothyroidism; Lipids; Lipoproteins; Metab | 1962 |
Effect of a thyroxine analogue (triiodothyropropionic acid) on the calcium-phosphorus metabolism.
Topics: Calcium; Calcium, Dietary; Humans; Hypercholesterolemia; Minerals; Phosphorus; Phosphorus, Dietary; | 1963 |
[Prolonged administration of thyroid derivatives in patients with hypercholesterolemia].
Topics: Humans; Hypercholesterolemia; Thyroid Gland; Thyroid Hormones; Triiodothyronine | 1963 |
[ISOTOPE TESTS OF RADIO-THYROXIN HALF-LIFE AND IN VITRO ERYTHROCYTE FIXATION OF LABELLED TRIIODOTHYRONINE].
Topics: Anorexia Nervosa; Erythrocytes; Goiter; Graves Disease; Half-Life; Hypercholesterolemia; Hyperthyroi | 1963 |
[TRIPARANOL, L-TRIIODOTHYRONINE AND 3-PYRIDYL ACETIC ACID IN THE CONTROL OF CHOLESTEROLEMIA. A COMPARATIVE STUDY].
Topics: Acetates; Acetic Acid; Arteriosclerosis; Hypercholesterolemia; Niacin; Nicotinic Acids; Triiodothyro | 1963 |
REDUCTION OF SERUM TRIGLYCERIDES IN PATIENTS TREATED WITH SODIUM D-THYROXINE.
Topics: Blood Chemical Analysis; Child; Dextrothyroxine; Glycerides; Hypercholesterolemia; Hyperlipidemias; | 1963 |
THE SEPARATE HYPOLIPOPROTEINEMIC EFFECTS OF DEXTROTHYROXINE AND ETHYL CHLOROPHENOXYISOBUTYRATE.
Topics: Androsterone; Biomedical Research; Blood Chemical Analysis; Blood Proteins; Body Weight; Butyrates; | 1964 |
[THE USE OF DRUGS IN THE CONTROL OF CHOLESTEROLEMIA].
Topics: Arteriosclerosis; Diet; Hypercholesterolemia; Niacin; Nicotinic Acids; Thyroxine; Toxicology; Triiod | 1963 |
THYROXINE ANALOGUES AS HYPOCHOLESTEROLEMIC AGENTS.
Topics: Coronary Disease; Humans; Hypercholesterolemia; Thyroxine; Triiodothyronine | 1964 |
THE 131-I-TRIIODOTHYRONINE-RESIN UPTAKE TEST.
Topics: Acidosis; Antithyroid Agents; Basal Metabolism; Choriocarcinoma; Erythrocytes; Hypercholesterolemia; | 1964 |
[THE TREATMENT OF HYPERLIPEMIAS AND HYPERCHOLESTEREMIAS WITH D-TRIIODOTHYRONINE].
Topics: Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type III; T | 1964 |
[POSSIBILITIES AND LIMITS OF AMBULATORY TREATMENT OF THE DYSLIPIDOSES IN CORONARY DISEASE WITH TRIAC (TRIIODOTHYROACETIC ACID). USE OF TRIAC ALONE].
Topics: Coronary Disease; Electrocardiography; Humans; Hypercholesterolemia; Lipoproteins; Thyroid Hormones; | 1964 |
[D-TRIIODOTHYRONINE TREATMENT OF ESSENTIAL HYPERLIPEMIA AND HYPERCHOLESTEREMIA].
Topics: Drug Therapy; Hypercholesterolemia; Hyperlipidemias; Triiodothyronine | 1964 |
D-TRI-IODOTHYRONINE EFFECT ON SERUM CHOLESTEROL. CLINICAL TRIAL IN HYPERCHOLESTEROLEMIC PATIENTS.
Topics: Biomedical Research; Cholesterol; Drug Therapy; Hypercholesterolemia; Placebos; Toxicology; Triiodot | 1965 |
D-Tri-iodothyronine treatment of hypercholesterolemia in patients with heart disease.
Topics: Cholesterol; Coronary Disease; Diuretics; Heart Diseases; Humans; Hypercholesterolemia; Triiodothyro | 1962 |
Thyroid analogue therapy in primary hypercholesteremia with xanthomatosis.
Topics: Antineoplastic Agents, Hormonal; Cholesterol; Hypercholesterolemia; Lipidoses; Thyroid Gland; Triiod | 1962 |
Enhanced serum cholesterol and triglyceride levels in bulimia nervosa: relationships to psychiatric comorbidity, psychopathology and hormonal variables.
Topics: Adult; Anorexia Nervosa; Blood Glucose; Borderline Personality Disorder; Bulimia; Cholesterol; Comor | 2005 |
Selective thyroid receptor modulation by GC-1 reduces serum lipids and stimulates steps of reverse cholesterol transport in euthyroid mice.
Topics: Acetates; Analysis of Variance; Animals; Bile Acids and Salts; Cardiovascular Diseases; CD36 Antigen | 2005 |
Hypercholesterolemia and apolipoprotein B expression: regulation by selenium status.
Topics: Animals; Apolipoproteins B; Cholesterol; Cholesterol, Dietary; Cholesterol, LDL; Down-Regulation; Gl | 2005 |
Modulation of hypercholesterolemia-induced alterations in apolipoprotein B and HMG-CoA reductase expression by selenium supplementation.
Topics: Animals; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Dietary Supplements; Gene Expression Regu | 2006 |
Hypercholesterolemia and LDL receptor mRNA expression: modulation by selenium supplementation.
Topics: Animals; Cholesterol; Dietary Supplements; Glutathione Peroxidase; Hypercholesterolemia; Lipoprotein | 2006 |
Cardio-protective role of terazosin is possibly mediated through alteration in thyroid function.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Glucose; Cholesterol, Dietary; Disease Models, Animal; | 2006 |
Effect of thyroxine and growth hormone on the hypercholesterolemia of growth hormone deficiency.
Topics: Child; Cholesterol; Growth Hormone; Humans; Hypercholesterolemia; Hypothyroidism; Thyroxine; Triiodo | 1984 |
Hepatic dysfunction in primary hypothyroidism.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Cholesterol; Female; Humans; Hypercholesterole | 1984 |
A possible explanation of myxedema and hypercholesterolemia in hypothyroidism: control of lysosomal hyaluronidase and cholesterol esterase by thyroid hormones.
Topics: Acid Phosphatase; Animals; Arteriosclerosis; Carboxylic Ester Hydrolases; Enzyme Activation; Hyaluro | 1981 |
Demonstration of potent lipid-lowering activity by a thyromimetic agent devoid of cardiovascular and thermogenic effects.
Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Binding, Competitive; Body Temperature; Carcino | 1996 |
Decrease in myocardial Na(+)-K(+)-ATPase activity and ouabain binding sites in hypercholesterolemic rabbits.
Topics: 5'-Nucleotidase; Animals; Binding Sites; Cholesterol; Cholesterol, Dietary; Hypercholesterolemia; Ma | 1997 |
Dose-dependent suppression of transplant arteriosclerosis in aorta-allografted, cholesterol-clamped rabbits. Suppression not eliminated by the cholesterol-raising effect of cyclosporine.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Diseases; Arteriosclerosis; Blood Vessel Prosthes | 1997 |
Towards gene therapy to enhance apolipoprotein AI expression.
Topics: Animals; Apolipoprotein A-I; Chickens; Gene Expression Regulation; Genetic Therapy; Hypercholesterol | 1997 |
Central cooling effects in patients with hypercholesterolaemia.
Topics: Adult; Aged; Body Composition; Body Temperature Regulation; Cholesterol; Cholesterol, HDL; Cholester | 1998 |
Endocrine markers of semistarvation in healthy lean men in a multistressor environment.
Topics: Adult; Biomarkers; Body Composition; Cholesterol; Endocrine Glands; Energy Metabolism; Food; Humans; | 2000 |
The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity.
Topics: Acetates; Animals; Blotting, Northern; Body Weight; Dose-Response Relationship, Drug; Heart; Hemodyn | 2000 |
Thyroid hormone receptor beta-deficient mice show complete loss of the normal cholesterol 7alpha-hydroxylase (CYP7A) response to thyroid hormone but display enhanced resistance to dietary cholesterol.
Topics: Animals; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholesterol, Dietary; DNA-Binding Proteins; H | 2000 |
Effects of a thyromimetic on apolipoprotein B-100 in rats.
Topics: Animals; Anticholesteremic Agents; APOBEC-1 Deaminase; Apolipoprotein B-100; Apolipoproteins B; Cyti | 2000 |
Hypercholesterolemia in Shetland sheepdogs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bilirubin; Blood Glucose; Blood Proteins | 2000 |
[Ischemic heart disease and metabolic syndrome X (family study)].
Topics: Adolescent; Adult; Apolipoproteins B; Arteriosclerosis; Autonomic Nervous System Diseases; Body Weig | 2000 |
Association between exaggerated responsiveness to thyrotrophin-releasing hormone and hypercholesterolaemia.
Topics: Adult; Aged; Autoantibodies; Cholesterol; Female; Humans; Hypercholesterolemia; Hypothyroidism; Male | 1977 |
["Twisted peak" ventricular fibrillation in myxedema. Case report].
Topics: Arrhythmias, Cardiac; Electric Stimulation; Female; Humans; Hypercholesterolemia; Middle Aged; Myxed | 1979 |
Increased mean serum thyrotropin in apparently euthyroid hypercholesterolemic patients: does it mean occult hypothyroidism?
Topics: Female; Humans; Hypercholesterolemia; Hypothyroidism; Male; Thyrotropin; Thyroxine; Triiodothyronine | 1991 |
Effect of thyroid hormone on hepatic cholesterol 7 alpha hydroxylase, LDL receptor, HMG-CoA reductase, farnesyl pyrophosphate synthetase and apolipoprotein A-I mRNA levels in hypophysectomized rats.
Topics: Animals; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins A; Base Sequence; Blotting, N | 1990 |
Thyroid dysfunction and hypercholesterolaemia in the general population of Glasgow, Scotland.
Topics: Adult; Cholesterol; Female; Humans; Hypercholesterolemia; Hypothyroidism; Male; Middle Aged; Scotlan | 1988 |
[Decreasing effect of DL-alpha-methylthyroxine-ethylester, D-thyroxine (DT4), D-triiodothyronine (DT3) and a combination of DT4 + DT3 on serum lipids in primary hyperlipoproteinemia Type IIa and b].
Topics: Depression, Chemical; Drug Therapy, Combination; Humans; Hypercholesterolemia; Lipid Mobilization; L | 1974 |