triiodothyronine has been researched along with Dyslipidemia in 19 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone, a thyroid hormone-like molecule, can induce dyslipidemia and thyroid dysfunction." | 7.83 | Dronedarone and Amiodarone Induce Dyslipidemia and Thyroid Dysfunction in Rats. ( Chen, SJ; Jiang, LQ; Ran, Z; Xu, JJ; Ying, W; Zhao, SG, 2016) |
| " 3,5-diiodothyronine (T2) has been used with success in rat models of dyslipidemia and NAFLD, but the outcome of a clinical trial with a synthetic T2 analogue was disappointing." | 5.05 | Thyroid Hormone Analogues: An Update. ( Zucchi, R, 2020) |
| "Amiodarone, a thyroid hormone-like molecule, can induce dyslipidemia and thyroid dysfunction." | 3.83 | Dronedarone and Amiodarone Induce Dyslipidemia and Thyroid Dysfunction in Rats. ( Chen, SJ; Jiang, LQ; Ran, Z; Xu, JJ; Ying, W; Zhao, SG, 2016) |
| "To investigate the iodine status and the prevalence of thyroid disease and dyslipidemia in adults living in areas of excessive iodine in water in Hebei Province, and to explore the impact of excessive iodine intake on dyslipidemia." | 3.78 | [Thyroid function and serum lipids of adults living in areas of excessive iodine in water in Hebei province]. ( Li, H; Liu, H; Sang, Z; Tan, L; Wei, W; Wen, S; Zhang, G; Zhang, W; Zhao, N, 2012) |
| "Dyslipidemia is highly prevalent and associated with the long-term prognosis of SLE." | 1.56 | Clinical significance of non-thyroidal illness syndrome on disease activity and dyslipidemia in patients with SLE. ( Chen, Z; Hu, W; Hua, B; Huang, S; Liu, L; Ma, X; Sun, L; Wang, H; Xu, X; Zhang, X, 2020) |
| "Hypothyroidism was successfully induced in PTU/LI mice." | 1.39 | Decreased expression of hepatic low-density lipoprotein receptor-related protein 1 in hypothyroidism: a novel mechanism of atherogenic dyslipidemia in hypothyroidism. ( Cha, BS; Choi, SH; Jang, HC; Kim, HJ; Kim, HM; Lim, S; Moon, JH; Park, YJ, 2013) |
| "Hypercholesterolemia is one of the most representative disorders of the common diseases." | 1.37 | Multi-center study on the prevalence of hypothyroidism in patients with hypercholesterolemia. ( Araki, R; Hata, S; Ise, T; Kimura, H; Miyazaki, Y; Naruse, M; Ogo, A; Ohtani, S; Saito, M; Sawamura, M; Shimatsu, A; Shimbo, T; Tagami, T; Tanaka, M; Tanaka, T; Yonezawa, K, 2011) |
| "Body weight was increased from 165 days old onwards in NIC offspring." | 1.35 | Short- and long-term effects of maternal nicotine exposure during lactation on body adiposity, lipid profile, and thyroid function of rat offspring. ( Abreu-Villaça, Y; Fagundes, AT; Lisboa, PC; Moura, EG; Nogueira Neto, JF; Oliveira, E; Passos, MC; Rios, AS; Santos-Silva, AP, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 13 (68.42) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Shiohara, H | 1 |
| Nakamura, T | 1 |
| Kikuchi, N | 1 |
| Ozawa, T | 1 |
| Nagano, R | 1 |
| Matsuzawa, A | 1 |
| Ohnota, H | 1 |
| Miyamoto, T | 1 |
| Ichikawa, K | 1 |
| Hashizume, K | 1 |
| Kelly, MJ | 1 |
| Pietranico-Cole, S | 1 |
| Larigan, JD | 1 |
| Haynes, NE | 1 |
| Reynolds, CH | 1 |
| Scott, N | 1 |
| Vermeulen, J | 1 |
| Dvorozniak, M | 1 |
| Conde-Knape, K | 1 |
| Huang, KS | 1 |
| So, SS | 1 |
| Thakkar, K | 1 |
| Qian, Y | 1 |
| Banner, B | 1 |
| Mennona, F | 1 |
| Danzi, S | 1 |
| Klein, I | 2 |
| Taub, R | 1 |
| Tilley, J | 1 |
| Liu, Y | 3 |
| Ma, M | 3 |
| Li, L | 3 |
| Liu, F | 3 |
| Li, Z | 3 |
| Yu, L | 3 |
| Yang, T | 3 |
| Wang, Y | 3 |
| Gao, S | 6 |
| Yang, R | 3 |
| Yu, C | 3 |
| Zucchi, R | 1 |
| Zhang, X | 1 |
| Liu, L | 1 |
| Ma, X | 1 |
| Hu, W | 1 |
| Xu, X | 1 |
| Huang, S | 1 |
| Hua, B | 1 |
| Wang, H | 1 |
| Chen, Z | 1 |
| Sun, L | 1 |
| Khan, M | 1 |
| Mukherjee, S | 1 |
| Bank, S | 1 |
| Maiti, S | 1 |
| Lange, T | 1 |
| Budde, K | 1 |
| Homuth, G | 1 |
| Kastenmüller, G | 1 |
| Artati, A | 1 |
| Krumsiek, J | 1 |
| Völzke, H | 1 |
| Adamski, J | 1 |
| Petersmann, A | 1 |
| Völker, U | 1 |
| Nauck, M | 1 |
| Friedrich, N | 1 |
| Pietzner, M | 1 |
| Biondi, B | 1 |
| Moon, JH | 1 |
| Kim, HJ | 1 |
| Kim, HM | 1 |
| Choi, SH | 1 |
| Lim, S | 1 |
| Park, YJ | 1 |
| Jang, HC | 1 |
| Cha, BS | 1 |
| Jiang, LQ | 1 |
| Chen, SJ | 1 |
| Xu, JJ | 1 |
| Ran, Z | 1 |
| Ying, W | 1 |
| Zhao, SG | 1 |
| Salerno, M | 1 |
| Capalbo, D | 1 |
| Cerbone, M | 1 |
| De Luca, F | 1 |
| Le, TN | 1 |
| Celi, FS | 1 |
| Wickham, EP | 1 |
| Parmar, HS | 1 |
| Kar, A | 1 |
| Oliveira, E | 1 |
| Moura, EG | 1 |
| Santos-Silva, AP | 1 |
| Fagundes, AT | 1 |
| Rios, AS | 1 |
| Abreu-Villaça, Y | 1 |
| Nogueira Neto, JF | 1 |
| Passos, MC | 1 |
| Lisboa, PC | 1 |
| Ladenson, PW | 1 |
| Kristensen, JD | 1 |
| Ridgway, EC | 1 |
| Olsson, AG | 1 |
| Carlsson, B | 1 |
| Baxter, JD | 1 |
| Angelin, B | 1 |
| Tagami, T | 1 |
| Kimura, H | 1 |
| Ohtani, S | 1 |
| Tanaka, T | 2 |
| Hata, S | 1 |
| Saito, M | 1 |
| Miyazaki, Y | 1 |
| Araki, R | 1 |
| Tanaka, M | 1 |
| Yonezawa, K | 1 |
| Sawamura, M | 1 |
| Ise, T | 1 |
| Ogo, A | 1 |
| Shimbo, T | 1 |
| Shimatsu, A | 1 |
| Naruse, M | 1 |
| Han, H | 1 |
| Xin, P | 1 |
| Zhao, L | 1 |
| Xu, J | 1 |
| Xia, Y | 1 |
| Yang, X | 1 |
| Sun, X | 1 |
| Hao, L | 1 |
| Wanjia, X | 1 |
| Chenggang, W | 1 |
| Aihong, W | 1 |
| Xiaomei, Y | 1 |
| Jiajun, Z | 1 |
| Chunxiao, Y | 1 |
| Jin, X | 1 |
| Yinglong, H | 1 |
| Ling, G | 1 |
| Li, H | 1 |
| Sang, Z | 1 |
| Tan, L | 1 |
| Zhao, N | 1 |
| Wei, W | 1 |
| Zhang, G | 1 |
| Liu, H | 1 |
| Wen, S | 1 |
| Zhang, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II, Placebo-Controlled, Double-Blind, Randomised, 12-Week, Parallel-Group Study to Assess the Efficacy of Different Doses of KB2115 as Add on to Statin Treatment in Patients With Dyslipidemia[NCT00593047] | Phase 2 | 180 participants (Anticipated) | Interventional | 2007-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for triiodothyronine and Dyslipidemia
| Article | Year |
|---|---|
Thyroid Hormone Analogues: An Update.
Topics: Acetates; Anilides; Animals; Central Nervous System Diseases; Clinical Trials as Topic; Diiodothyron | 2020 |
Subclinical hypothyroidism in childhood - current knowledge and open issues.
Topics: Anticonvulsants; Antiviral Agents; Asymptomatic Diseases; Atherosclerosis; Bone Diseases, Metabolic; | 2016 |
1 trial available for triiodothyronine and Dyslipidemia
| Article | Year |
|---|---|
Use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia.
Topics: Adult; Anilides; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combination; Dyslipidemias; Fe | 2010 |
16 other studies available for triiodothyronine and Dyslipidemia
| Article | Year |
|---|---|
Discovery of novel indane derivatives as liver-selective thyroid hormone receptor β (TRβ) agonists for the treatment of dyslipidemia.
Topics: Animals; Arginine; Cholesterol; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; D | 2012 |
Discovery of 2-[3,5-dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β agonist in clinical trials for the treatment of dys
Topics: Animals; Bone Density; Clinical Trials as Topic; Drug Discovery; Dyslipidemias; Humans; Male; Mice; | 2014 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Association between sensitivity to thyroid hormones and dyslipidemia in patients with coronary heart disease.
Topics: Coronary Disease; Dyslipidemias; Glucose; Humans; Retrospective Studies; Thyroid Hormone Resistance | 2023 |
Clinical significance of non-thyroidal illness syndrome on disease activity and dyslipidemia in patients with SLE.
Topics: Adult; Apolipoprotein A-I; Apolipoproteins B; Dyslipidemias; Euthyroid Sick Syndromes; Female; Human | 2020 |
Role of Thyroid Hormone and Oxidant Stress in Cardiovascular Diseases.
Topics: Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Dyslipidemias; Heart | 2021 |
Comprehensive Metabolic Profiling Reveals a Lipid-Rich Fingerprint of Free Thyroxine Far Beyond Classic Parameters.
Topics: Adult; Blood Chemical Analysis; Dyslipidemias; Female; Germany; Humans; Lipid Metabolism; Lipids; Ma | 2018 |
Persistent Dyslipidemia in Patients With Hypothyroidism: A Good Marker for Personalized Replacement Therapy?
Topics: Biomarkers; Drug Therapy, Combination; Dyslipidemias; Hormone Replacement Therapy; Humans; Hypothyro | 2019 |
Decreased expression of hepatic low-density lipoprotein receptor-related protein 1 in hypothyroidism: a novel mechanism of atherogenic dyslipidemia in hypothyroidism.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Down-Regulation; Dyslipidemias; | 2013 |
Dronedarone and Amiodarone Induce Dyslipidemia and Thyroid Dysfunction in Rats.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Dronedarone; Dyslipidemias; Lipid Metabolism; Lipids; L | 2016 |
Thyrotropin Levels Are Associated with Cardiometabolic Risk Factors in Euthyroid Adolescents.
Topics: Adolescent; Biomarkers; Cardiovascular Diseases; Child; Cohort Studies; Cross-Sectional Studies; Dys | 2016 |
Possible amelioration of atherogenic diet induced dyslipidemia, hypothyroidism and hyperglycemia by the peel extracts of Mangifera indica, Cucumis melo and Citrullus vulgaris fruits in rats.
Topics: Animals; Ascorbic Acid; Atherosclerosis; Blood Glucose; Citrullus; Creatine Kinase, MB Form; Cucumis | 2008 |
Short- and long-term effects of maternal nicotine exposure during lactation on body adiposity, lipid profile, and thyroid function of rat offspring.
Topics: Adipose Tissue; Animals; Animals, Suckling; Body Weight; Dyslipidemias; Female; Infusion Pumps, Impl | 2009 |
Multi-center study on the prevalence of hypothyroidism in patients with hypercholesterolemia.
Topics: Adult; Aged; Dyslipidemias; Female; Humans; Hypercholesterolemia; Hypolipidemic Agents; Hypothyroidi | 2011 |
Excess iodine and high-fat diet combination modulates lipid profile, thyroid hormone, and hepatic LDLr expression values in mice.
Topics: Animals; Blotting, Western; Cholesterol; Cholesterol, LDL; Diet, High-Fat; Dyslipidemias; Female; Ge | 2012 |
A high normal TSH level is associated with an atherogenic lipid profile in euthyroid non-smokers with newly diagnosed asymptomatic coronary heart disease.
Topics: Aged; Aged, 80 and over; Asymptomatic Diseases; Blood Glucose; Cholesterol; Coronary Disease; Dyslip | 2012 |
[Thyroid function and serum lipids of adults living in areas of excessive iodine in water in Hebei province].
Topics: Adult; Autoantibodies; China; Dyslipidemias; Humans; Hypothyroidism; Iodides; Iodine; Lipids; Preval | 2012 |