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triiodothyronine and Dwarfism

triiodothyronine has been researched along with Dwarfism in 42 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Dwarfism: A genetic or pathological condition that is characterized by short stature and undersize. Abnormal skeletal growth usually results in an adult who is significantly below the average height.

Research Excerpts

ExcerptRelevanceReference
" Body weight, carcass fat, plasma growth hormone (GH), triiodothyronine (T3), thyroxine (T4), hepatic malic enzyme (ME) and citrate cleavage enzyme (CCE) activities were determined at 0, 2, 4 and 6 weeks."3.67Effect of the dw gene on growth, plasma hormone concentrations and hepatic enzyme activity in a randombred population of chickens. ( Marks, HL; Stewart, PA; Washburn, KW, 1984)
" Long-term administration of IGF-I induces a transitory decrease of both serum TSH and fT4, followed by a spontaneous rise to pretreatment or even higher values."2.67Effect of insulin-like growth factor I on the thyroid axis in patients with Laron-type dwarfism and healthy subjects. ( Anin, S; Ionesco, A; Klinger, B; Laron, Z, 1992)
" Treatment of these rats with human (h) GH significantly increased the LAGS level in a dose-response manner."1.29The role of growth hormone in regulation of low affinity glucocorticoid-binding sites from male rat liver microsomes. ( Boada, LD; Chirino, R; Díaz-Chico, BN; Díaz-Chico, JC; Fernández, L; López-Guerra, A; Valerón, PF, 1994)
"Such dwarfism is characterized by low circulating levels of T3 and T4."1.27Effects of dietary thyroid hormones on growth and serum T3, T4, and growth hormone in sex-linked dwarf chickens. ( Leung, FC; Taylor, JE; Van Iderstine, A, 1984)
"0-ppm T3 dosage level resulted in depressed body weights within both the K and ADW strains but produced no significant changes within the SLD strain."1.27Effects of triiodothyronine treatments on body and organ growth and the development of immune function in dwarf chickens. ( Lauterio, TJ; Marsh, JA; Scanes, CG, 1984)
"Treatment with triiodothyronine (T3) but not thyroxine (T4) (at 1 ppm in the diet from hatch) consistently and significantly reduced the growth rate and decreased the plasma concentrations of GH following TRH injection in normal (DwDw males or Dw-females), hemizygous dwarf (dw-) female, and heterozygous (Dwdw) male lines of broiler chickens."1.27Effect of thyroid hormones on growth hormone secretion in broiler chickens. ( Bowen, SJ; Denver, RJ; Scanes, CG, 1986)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199029 (69.05)18.7374
1990's9 (21.43)18.2507
2000's3 (7.14)29.6817
2010's1 (2.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vlaeminck-Guillem, V1
Espiard, S1
Flamant, F1
Wémeau, JL1
ZAHND, GR1
Blum, JW1
Elsasser, TH1
Greger, DL1
Wittenberg, S1
de Vries, F1
Distl, O1
Sato, T1
Kajiwara, S1
Miyamori, C1
Kato, T1
Ametov, AS1
Toritsina, LK1
Leung, FC2
Taylor, JE1
Van Iderstine, A1
Marsh, JA3
Lauterio, TJ3
Scanes, CG9
Gause, WC1
Sandhu, S1
Stewart, PA1
Washburn, KW1
Marks, HL1
Marsh, J1
Decuypere, E10
Rudas, P3
Thieriot-Prévost, G1
Schimpff, RM1
Bartha, T1
Dewil, E2
Kühn, ER6
Chirino, R1
López-Guerra, A1
Fernández, L1
Boada, LD1
Valerón, PF1
Díaz-Chico, JC1
Díaz-Chico, BN1
Buyse, J1
Tixier-Biochard, M1
Berghman, LR2
Huybrechts, LM7
Darras, VM5
Visser, TJ1
Hall, TR1
Vanderpooten, A2
Vasilatos-Younken, R1
Dunnington, EA2
Siegel, PB2
McMurtry, JP1
Spencer, GS1
Sakai, Y1
Yamashina, S1
Furudate, SI1
Van As, P1
Janssens, W1
Onagbesan, OM1
Bruggeman, V1
Buys, N1
Sanders, J1
Van Der Geyten, S1
Alcañiz, JJ1
Salto, L1
Barcelo, B1
Grandhi, RR5
Brown, RG4
Reinhart, BS3
Summers, JD3
Nutting, DF1
Klinger, B1
Ionesco, A1
Anin, S1
Laron, Z1
Tixier-Boichard, M1
Monvoisin, JL1
Coquerelle, G1
Charrier, J1
Simon, J1
Meeuwis, R1
Berghman, L1
Lam, SK1
Harvey, S1
Buonomo, FC2
Donoghue, DJ1
Hoshino, S2
Wakita, M2
Kobayashi, Y2
Kakegawa, T2
Suzuki, M2
Michielsen, R1
Bowen, SJ2
Denver, RJ1
Lilburn, MS1
Ngiam-Rilling, K1
Smith, JH1
Mellet, J1
Kobielowa, Z1
Szybiński, Z1
Gumiński, T1
Tarnawski, A1
Takeuchi, K1
Tada, H1
Suwa, S1

Reviews

2 reviews available for triiodothyronine and Dwarfism

ArticleYear
TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone.
    Presse medicale (Paris, France : 1983), 2015, Volume: 44, Issue:11

    Topics: Abnormalities, Multiple; Adolescent; Adult; Age of Onset; Bradycardia; Child; Codon, Nonsense; Dwarf

2015
[Radioimmunoassay in endocrinology].
    Meditsinskaia radiologiia, 1983, Volume: 28, Issue:8

    Topics: Adrenal Gland Diseases; C-Peptide; Diabetes Mellitus; Dwarfism; Glucagon; Growth Hormone; Humans; In

1983

Trials

1 trial available for triiodothyronine and Dwarfism

ArticleYear
Effect of insulin-like growth factor I on the thyroid axis in patients with Laron-type dwarfism and healthy subjects.
    Acta endocrinologica, 1992, Volume: 127, Issue:6

    Topics: Adolescent; Adult; Child; Dwarfism; Female; Humans; Injections, Intravenous; Injections, Subcutaneou

1992

Other Studies

39 other studies available for triiodothyronine and Dwarfism

ArticleYear
[REGULATION OF THE METABOLISM OF CARBOHYDRATES AND UNESTERIFIED FATTY ACIDS].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1963

    Topics: Addison Disease; Adipose Tissue; Blood Chemical Analysis; Carbohydrate Metabolism; Diabetes Mellitus

1963
Insulin-like growth factor type-1 receptor down-regulation associated with dwarfism in Holstein calves.
    Domestic animal endocrinology, 2007, Volume: 33, Issue:3

    Topics: Animals; Blotting, Western; Cattle; Cattle Diseases; Down-Regulation; Dwarfism; Female; Glucagon; Gr

2007
Na-K-dependent ATPase in red cells and thyroid status.
    Endocrinologia japonica, 1982, Volume: 29, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Dwarfism; Dwarfism, Pituitary; Eryth

1982
Effects of dietary thyroid hormones on growth and serum T3, T4, and growth hormone in sex-linked dwarf chickens.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 177, Issue:1

    Topics: Animals; Body Weight; Chickens; Diet; Dwarfism; Growth Hormone; Poultry Diseases; Thyroxine; Triiodo

1984
Effects of triiodothyronine treatments on body and organ growth and the development of immune function in dwarf chickens.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 177, Issue:1

    Topics: Animals; Antibody Formation; Body Weight; Chickens; Dwarfism; Erythrocytes; Female; Immunity; Liver;

1984
Enhanced growth and immune development in dwarf chickens treated with mammalian growth hormone and thyroxine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1984, Volume: 175, Issue:3

    Topics: Animals; Antibody Formation; Bursa of Fabricius; Chickens; Dwarfism; Growth; Growth Hormone; Male; O

1984
Effect of the dw gene on growth, plasma hormone concentrations and hepatic enzyme activity in a randombred population of chickens.
    Growth, 1984,Spring, Volume: 48, Issue:1

    Topics: Animals; ATP Citrate (pro-S)-Lyase; Body Weight; Chickens; Dwarfism; Female; Genes, Recessive; Genot

1984
Abnormalities in the plasma concentrations of thyroxine, tri-iodothyronine and growth hormone in sex-linked dwarf and autosomal dwarf White Leghorn domestic fowl (Gallus domesticus).
    The Journal of endocrinology, 1983, Volume: 97, Issue:1

    Topics: Animals; Chickens; Dwarfism; Female; Genes, Recessive; Growth Hormone; Male; Sexual Maturation; Thyr

1983
A hormonally controlled serum factor stimulating the thymidine uptake into lectin-activated lymphocytes.
    Acta endocrinologica, 1981, Volume: 98, Issue:3

    Topics: Acromegaly; Adolescent; Adult; Blood; Child; Child, Preschool; Dwarfism; Dwarfism, Pituitary; Female

1981
Kinetic parameters of plasma thyroid hormone and thyroid hormone receptors in a dwarf and control line of chicken.
    General and comparative endocrinology, 1994, Volume: 96, Issue:1

    Topics: Animals; Chickens; Dwarfism; Female; Half-Life; Kinetics; Male; Metabolic Clearance Rate; Receptors,

1994
The role of growth hormone in regulation of low affinity glucocorticoid-binding sites from male rat liver microsomes.
    Endocrinology, 1994, Volume: 134, Issue:3

    Topics: Animals; Binding Sites; Corticosterone; Dexamethasone; Dwarfism; Growth Hormone; Hypophysectomy; Hyp

1994
Growth hormone secretory characteristics of sex-linked dwarf and normal-sized chickens reared on a control or on a 3,3',5-triiodothyronine-supplemented diet.
    General and comparative endocrinology, 1994, Volume: 93, Issue:3

    Topics: Animals; Chickens; Dwarfism; Genetic Linkage; Growth Hormone; Male; Poultry Diseases; Sex Chromosome

1994
Endogenous growth hormone controls high plasma levels of 3,3',5-triiodothyronine (T3) in growing chickens by decreasing the T3-degrading type III deiodinase activity.
    Domestic animal endocrinology, 1993, Volume: 10, Issue:1

    Topics: Analysis of Variance; Animals; Chickens; Dwarfism; Female; Growth Hormone; Hypophysectomy; Iodide Pe

1993
Tissue-specific alterations in insulin-like growth factor-I concentrations in response to 3,3',5-triiodo-L-thyronine supplementation in the growth hormone receptor-deficient sex-linked dwarf chicken.
    General and comparative endocrinology, 1997, Volume: 105, Issue:1

    Topics: Adipose Tissue; Animals; Chickens; Disease Models, Animal; Dwarfism; Female; Genetic Linkage; Growth

1997
The regulation of GH-dependent hormones and enzymes after feed restriction in dwarf and control chickens.
    Life sciences, 1999, Volume: 64, Issue:16

    Topics: Animals; Blood Glucose; Body Weight; Chickens; Dwarfism; Food Deprivation; Genotype; Growth Hormone;

1999
Missing secretory granules, dilated endoplasmic reticulum, and nuclear dislocation in the thyroid gland of rdw rats with hereditary dwarfism.
    The Anatomical record, 2000, 05-01, Volume: 259, Issue:1

    Topics: Animals; Cell Nucleus; Cytoplasmic Granules; Dwarfism; Endoplasmic Reticulum, Rough; Hypothyroidism;

2000
Quantification of growth hormone receptor extra- and intracellular domain gene expression in chicken liver by quantitative competitive RT-PCR.
    General and comparative endocrinology, 2001, Volume: 122, Issue:2

    Topics: Aging; Animals; Chickens; Dwarfism; Extracellular Space; Female; Gene Expression; Growth Hormone; Li

2001
GH secretion in two siblings with Laron's dwarfism: the effects of glucose, arginine, somatostatin, and bromocryptine.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:2

    Topics: Adult; Arginine; Bromocriptine; Child; Dwarfism; Female; Glucose; Growth Hormone; Humans; Kinetics;

1978
Thyroid metabolism in the recessive sex-linked dwarf female chicken. 2. Binding of thyroid hormones by serum proteins.
    Poultry science, 1975, Volume: 54, Issue:2

    Topics: Animals; Beta-Globulins; Blood Proteins; Chickens; Dwarfism; Female; gamma-Globulins; Genes, Recessi

1975
Effects of growth hormone, thyroxine, and age on diaphragm muscle from dwarf mice.
    Endocrinology, 1976, Volume: 99, Issue:6

    Topics: Age Factors; Aminoisobutyric Acids; Animals; Diaphragm; Dwarfism; Growth Hormone; Insulin; Leucine;

1976
Thyroid metabolism in the recessive sex-linked dwarf female chicken. 1. Age related changes in thyroid hormone synthesis and circulating thyroid hormone levels.
    Poultry science, 1975, Volume: 54, Issue:2

    Topics: Age Factors; Animals; Chickens; Diiodotyrosine; Dwarfism; Female; Genes, Recessive; Monoiodotyrosine

1975
Thyroid metabolism in the recessive sex-linked dwarf female chicken. 4. The influence of exogenous thyroid hormones on amino acid uptake by plasma and tissues.
    Poultry science, 1975, Volume: 54, Issue:2

    Topics: Alanine; Amino Acids; Animals; Chickens; Dwarfism; Female; Genes, Recessive; Kidney; Liver; Lysine;

1975
Thyroid metabolism in the recessive sex-linked dwarf female chicken. 3. The influence of exogenous thyroid hormones in glycogen metabolism.
    Poultry science, 1975, Volume: 54, Issue:2

    Topics: Animals; Chickens; Dwarfism; Female; Genes, Recessive; Glycogen; Liver Glycogen; Poultry Diseases; S

1975
Thyroid metabolism in the recessive sex-linked dwarf female chicken. 5. Effects of exogenous thyroid hormones on amino acid uptake by eggs.
    Poultry science, 1975, Volume: 54, Issue:2

    Topics: Amino Acids; Animals; Chickens; Dwarfism; Eggs; Female; Genes, Recessive; Ovalbumin; Poultry Disease

1975
Effects of insulin-like growth factor-I (IGF-I) infusion and dietary tri-iodothyronine (T3) supplementation on growth, body composition and plasma hormone levels in sex-linked dwarf mutant and normal chickens.
    The Journal of endocrinology, 1992, Volume: 133, Issue:1

    Topics: Animals; Body Composition; Body Weight; Bone Development; Cartilage; Chickens; Diet; Dose-Response R

1992
Impaired peripheral T3 production but normal induced thyroid hormone secretion in the sex-linked dwarf chick embryo.
    Reproduction, nutrition, development, 1990, Volume: 30, Issue:2

    Topics: Animals; Chick Embryo; Corticosterone; Corticotropin-Releasing Hormone; Dwarfism; Growth Hormone; Io

1990
A decreased capacity of hepatic growth hormone (GH) receptors and failure of thyrotrophin-releasing hormone to stimulate the peripheral conversion of thyroxine into triiodothyronine in sex-linked dwarf broiler hens.
    Reproduction, nutrition, development, 1989, Volume: 29, Issue:4

    Topics: Animals; Chickens; Dwarfism; Growth Hormone; Liver; Receptors, Somatotropin; Thyrotropin-Releasing H

1989
Thyroid function in sex-linked and autosomal dwarf chickens.
    General and comparative endocrinology, 1989, Volume: 76, Issue:2

    Topics: Animals; Chickens; Dwarfism; Female; Genetic Linkage; Male; Sex Chromosomes; Somatostatin; Thyroid G

1989
Plasma concentrations of insulin like growth factors (IGF-)I and IGF-II in dwarf and normal chickens of high and low weight selected lines.
    Growth, development, and aging : GDA, 1989,Winter, Volume: 53, Issue:4

    Topics: Animals; Body Weight; Chickens; Dwarfism; Insulin-Like Growth Factor I; Insulin-Like Growth Factor I

1989
Effects of thyroid hormones on cartilage sulphation in sex-linked dwarf chickens.
    Acta endocrinologica, 1989, Volume: 121, Issue:1

    Topics: Animals; Body Weight; Cartilage; Chick Embryo; Chickens; Dwarfism; Female; Male; Sulfates; Thyroxine

1989
Effect of the sex-linked dwarf gene on thyrotrophic and somatotrophic axes in the chick embryo.
    Reproduction, nutrition, development, 1989, Volume: 29, Issue:2

    Topics: Animals; Chick Embryo; Dwarfism; Genetic Linkage; Iodide Peroxidase; Sex Chromosomes; Somatomedins;

1989
Growth, protein synthesis and plasma concentrations of growth hormone, thyroxine and triiodothyronine in dwarf, control and growth-selected strains of broiler-type domestic fowl.
    Comparative biochemistry and physiology. A, Comparative physiology, 1986, Volume: 83, Issue:4

    Topics: Aging; Animals; Body Weight; Chickens; Dwarfism; Growth Hormone; Male; Organ Size; Proteins; Species

1986
Influence of triiodothyronine and growth hormone on growth of dwarf and normal chickens: interactions of hormones and genotype.
    Comparative biochemistry and physiology. A, Comparative physiology, 1987, Volume: 86, Issue:1

    Topics: Aging; Animals; Body Weight; Chickens; Dwarfism; Genotype; Growth Hormone; Male; Species Specificity

1987
Effect of thyroid hormones on growth hormone secretion in broiler chickens.
    Poultry science, 1986, Volume: 65, Issue:2

    Topics: Animals; Body Weight; Chickens; Dwarfism; Female; Genotype; Growth Hormone; Male; Species Specificit

1986
Thyroid hormone response to thyrotrophin releasing hormone (TRH) in the sex-linked dwarf chicken.
    Endocrinologia japonica, 1986, Volume: 33, Issue:5

    Topics: Aging; Animals; Chickens; Dwarfism; Female; Injections, Intravenous; Injections, Subcutaneous; Male;

1986
The relationship between age and genotype and circulating concentrations of triiodothyronine (T3), thyroxine (T4), and growth hormone in commercial meat strain chickens.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 182, Issue:3

    Topics: Aging; Animals; Body Weight; Chickens; Dwarfism; Female; Genetic Linkage; Genotype; Growth Hormone;

1986
[Study of ribosomal level in the liver of the normal and dwarf mouse].
    Biochimie, 1973, Volume: 55, Issue:2

    Topics: Animals; Dwarfism; Growth Hormone; Liver; Mice; Polyribosomes; Ribosomes; Spectrophotometry; Subcell

1973
[ 132 -I uptake, the Thiopac test and percentage of free thyroxine in children with arrested somatic development].
    Przeglad lekarski, 1971, Jun-28, Volume: 27, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Dwarfism; Female; Growth; Growth Disorders; Humans; Hypothyroid

1971
Response of human growth hormone to insulin-induced hypoglycemia in children with thyroid disorders: diminished response and improvement with treatment.
    Paediatria Universitatis Tokyo, 1968, Volume: 16

    Topics: Adolescent; Child; Child, Preschool; Dwarfism; Female; Growth Hormone; Humans; Hypoglycemia; Insulin

1968