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triiodothyronine and Dwarfism, Pituitary

triiodothyronine has been researched along with Dwarfism, Pituitary in 18 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Dwarfism, Pituitary: A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

Research Excerpts

ExcerptRelevanceReference
"Recombinant hGH treatment may alter thyroid hormone metabolism and we have recently reported that 50% of patients with GH deficiency (GHD) due to organic lesions, previously not treated with thyroxine, developed hypothyroidism during treatment with recombinant human GH (rhGH)."5.10Recombinant hGH replacement therapy and the hypothalamus-pituitary-thyroid axis in children with GH deficiency: when should we be concerned about the occurrence of central hypothyroidism? ( Arosio, M; Beck-Peccoz, P; Cappiello, V; Epaminonda, P; Ferrante, E; Giavoli, C; Porretti, S; Ronchi, CL; Travaglini, P, 2003)
" nutriments, and hypothyroidism on the peripheral conversion of thyroxine (T4) to 3,3', 5-triiodothyronine (T3) in the rat and mouse, an in vitro system for assessing T4 conversion to T3 by fresh liver homogenates was used."3.66Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat. ( Braverman, LE; Fang, SL; Harris, AR; Vagenakis, AG, 1978)
" As a control group, six patients with primary hypothyroidism received gradually increasing doses of L-T4 for 4-week periods, and TSH response to TRH was tested at the end of each dosage of L-T4, until complete inhibition of TSH release was obtained."1.26Low setting of feedback regulation of TSH secretion by thyroxine in pituitary dwarfism with TSH-releasing hormone deficiency. ( Ishiguro, K; Isumisawa, A; Sato, T; Suzuki, Y; Taketani, T, 1976)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199014 (77.78)18.7374
1990's1 (5.56)18.2507
2000's1 (5.56)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yamauchi, I1
Sakane, Y1
Yamashita, T1
Hirota, K1
Ueda, Y1
Kanai, Y1
Yamashita, Y1
Kondo, E1
Fujii, T1
Taura, D1
Sone, M1
Yasoda, A1
Inagaki, N1
De Bellis, A1
Bellastella, G1
Maiorino, MI1
Aitella, E1
Lucci, E1
Cozzolino, D1
Bellastella, A1
Bizzarro, A1
Giugliano, D1
Esposito, K1
ZAHND, GR1
Giavoli, C1
Porretti, S1
Ferrante, E1
Cappiello, V1
Ronchi, CL1
Travaglini, P1
Epaminonda, P1
Arosio, M1
Beck-Peccoz, P1
Sato, T3
Kajiwara, S1
Miyamori, C1
Kato, T1
van Buul-Offers, S1
Hackeng, WH1
Schopman, W1
Sobieszczyk, S1
Polańska, A1
Kosowicz, J1
Demura, R1
Yamaguchi, H1
Wakabayashi, I1
Demura, H1
Shizume, K1
Thieriot-Prévost, G1
Schimpff, RM1
Harris, AR1
Fang, SL1
Vagenakis, AG1
Braverman, LE1
Lombardi, G2
Minozzi, M2
Faggiano, M2
Carella, C2
Jaquet, P1
Carayon, P1
Oliver, C1
Suzukui, Y1
Taketani, T2
Ishiguro, K2
Masuyama, T1
Suzuki, Y1
Isumisawa, A1
Criscuolo, T1
Ishihara, M1
Wada, K1
Nakaya, T1
Yamawaki, M1
Matsumoto, Y1
Tixier-Boichard, M1
Monvoisin, JL1
Decuypere, E1
Huybrechts, LM1
Kühn, ER1
Gual, C1
Kastin, AJ1
Schally, AV1
Schwenk, A1
Geisen, K1

Reviews

1 review available for triiodothyronine and Dwarfism, Pituitary

ArticleYear
Clinical experience with hypothalamic releasing hormones. 1. Thyrotropin-releasing hormone.
    Recent progress in hormone research, 1972, Volume: 28

    Topics: Acromegaly; Adult; Amenorrhea; Craniopharyngioma; Dwarfism, Pituitary; Female; Humans; Hyperthyroidi

1972

Trials

1 trial available for triiodothyronine and Dwarfism, Pituitary

ArticleYear
Recombinant hGH replacement therapy and the hypothalamus-pituitary-thyroid axis in children with GH deficiency: when should we be concerned about the occurrence of central hypothyroidism?
    Clinical endocrinology, 2003, Volume: 59, Issue:6

    Topics: Adolescent; Child; Dwarfism, Pituitary; Female; Follow-Up Studies; Growth Hormone; Humans; Hypothala

2003

Other Studies

16 other studies available for triiodothyronine and Dwarfism, Pituitary

ArticleYear
Effects of growth hormone on thyroid function are mediated by type 2 iodothyronine deiodinase in humans.
    Endocrine, 2018, Volume: 59, Issue:2

    Topics: Acromegaly; Adult; Cell Line; Dwarfism, Pituitary; Female; Gene Expression Regulation; Hormone Repla

2018
Longitudinal behavior of autoimmune GH deficiency: from childhood to transition age.
    European journal of endocrinology, 2016, Volume: 174, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Autoantibodies; Autoimmune Hypophysitis; Child; Dwarfism, P

2016
[REGULATION OF THE METABOLISM OF CARBOHYDRATES AND UNESTERIFIED FATTY ACIDS].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1963

    Topics: Addison Disease; Adipose Tissue; Blood Chemical Analysis; Carbohydrate Metabolism; Diabetes Mellitus

1963
Na-K-dependent ATPase in red cells and thyroid status.
    Endocrinologia japonica, 1982, Volume: 29, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Dwarfism; Dwarfism, Pituitary; Eryth

1982
Thyroxine and triiodothyronine levels in Snell mice.
    Acta endocrinologica, 1983, Volume: 102, Issue:3

    Topics: Animals; Dwarfism, Pituitary; Female; Hormones; Humans; Male; Mice; Mice, Inbred Strains; Thyroxine;

1983
[Serum thyroxine, triiodothyronine and reverse triiodothyronine concentrations in patients with pituitary dwarfism].
    Endokrynologia Polska, 1984, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Child; Dwarfism, Pituitary; Female; Humans; Male; Thyroxine; Triiodothyronine; Tr

1984
The effect of hGH on hypothalamic-pituitary-thyroid function in patients with pituitary dwarfism.
    Acta endocrinologica, 1980, Volume: 93, Issue:1

    Topics: Dwarfism, Pituitary; Growth Hormone; Half-Life; Humans; Hypothalamo-Hypophyseal System; Thyroid Func

1980
A hormonally controlled serum factor stimulating the thymidine uptake into lectin-activated lymphocytes.
    Acta endocrinologica, 1981, Volume: 98, Issue:3

    Topics: Acromegaly; Adolescent; Adult; Blood; Child; Child, Preschool; Dwarfism; Dwarfism, Pituitary; Female

1981
Effect of starvation, nutriment replacement, and hypothyroidism on in vitro hepatic T4 to T3 conversion in the rat.
    Metabolism: clinical and experimental, 1978, Volume: 27, Issue:11

    Topics: Amino Acids; Animals; Blood Glucose; Diet; Dietary Carbohydrates; Dwarfism, Pituitary; Hydrogen-Ion

1978
Plasma immunoreactive T3, TSH and ACTH before and after provocative tests in idiopathic hypopituitary dwarfism.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Dwarfism, Pituitary; Female; Growth Hormone;

1975
Enhanced peripheral conversion of thyroxine to triiodothyronine during hGH therapy in GH deficient children.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Body Height; Child; Child, Preschool; Dwarfism, Pituitary; Growth Hormone; Humans

1977
Low setting of feedback regulation of TSH secretion by thyroxine in pituitary dwarfism with TSH-releasing hormone deficiency.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Aging; Child; Dwarfism, Pituitary; Feedback; Humans; Hypopituitarism; Hypothyroid

1976
[Technical notes and clinical use in the radioimmunologic determination of T 3].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1975, Volume: 11, Issue:2

    Topics: Dwarfism, Pituitary; Humans; Hyperthyroidism; Radioimmunoassay; Thyrotropin; Thyrotropin-Releasing H

1975
[Effects on HGH in the management of pituitary dwarfism].
    Horumon to rinsho. Clinical endocrinology, 1977, Volume: 25, Issue:7

    Topics: Adolescent; Child; Dwarfism, Pituitary; Growth Hormone; Humans; Male; Thyroxine; Triiodothyronine

1977
Effect of triiodothyronine supplementation on thyrotropin-releasing hormone-induced growth hormone secretion in sex-linked dwarf and normal chicks.
    General and comparative endocrinology, 1991, Volume: 84, Issue:1

    Topics: Analysis of Variance; Animals; Chickens; Dose-Response Relationship, Drug; Drug Antagonism; Dwarfism

1991
[Therapy of hypophyseal dwarfism].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:6

    Topics: Adolescent; Adult; Antibodies; Cortisone; Craniopharyngioma; Dwarfism, Pituitary; Female; Growth; Gr

1970