Page last updated: 2024-11-08

triiodothyronine and Disease

triiodothyronine has been researched along with Disease in 30 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Disease: A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Research Excerpts

ExcerptRelevanceReference
" Our findings suggest that the use of equilibrium dialysis of undiluted serum or ultrafiltration to measure serum free T4 concentrations will distinguish euthyroid hypothyroxinemic ICU patients from those with hypothyroidism."3.67Normal free thyroxine in critical nonthyroidal illnesses measured by ultrafiltration of undiluted serum and equilibrium dialysis. ( Hupart, KH; Pan, C; Shapiro, LE; Surks, MI, 1988)
"In 33 patients with various, mainly severe diseases a subnormal triiodothyronine concentration (T3) and a normal thyroxin concentration (T4) were found."3.65[The euthyreotic hypotriiodothyroninemia]. ( Gless, KH; Hüfner, M, 1975)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199024 (80.00)18.7374
1990's5 (16.67)18.2507
2000's1 (3.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BENUA, RS1
DOBYNS, BM1
NINMER, A1
BARNA, S2
FEUER, G2
REMENARNE, BI2
SZABO, G2
BROOKS, RV1
HETZEL, BS1
McSWINEY, RR1
PRUNTY, FT1
GOOLDEN, AW1
BURRELL, CD1
MALAMOS, B1
DAIKOS, G1
SAMARA, V1
BANSI, HW1
HUDSON, B1
WINIKOFF, D1
TAFT, HP1
MARTIN, FI1
MITCHELL, ML1
HARDEN, AB1
O'ROURKE, ME1
STEVENSON, C1
MANZUR, F1
BARZELATTO, J1
Wartofsky, L1
Baue, AE1
Günther, B1
Hartl, W1
Ackenheil, M1
Heberer, G1
McHenry, LE1
Loebel, JE1
Saxe, P1
Pannall, PR1
Fuller, WR1
Peisach, AR1
Marshall, J1
Stuart, S1
Reilly, CP1
Wellby, ML1
Bayer, MF2
McDougall, IR1
Robbins, J1
Geola, FL1
Chopra, IJ1
Geffner, DL1
Vos, RA1
De Jong, M1
Bernard, BF1
Docter, R1
Krenning, EP1
Hennemann, G1
Kluetsch, K1
Hotze, A1
Rao, GS1
Ghayad, E1
Choueiri Medlej, R1
Schlienger, JL1
Goichot, B1
Langton, JE1
Brent, GA1
Olsen, T1
Laurberg, P1
Weeke, J1
Hüfner, M1
Gless, KH1
Hay, ID1
Kaplan, MM1
Klee, GG1
Larsen, PR2
Spencer, CA1
Flattet, A1
Burger, AG1
Kaptein, EM1
Surks, MI1
Hupart, KH1
Pan, C1
Shapiro, LE1
Semple, CG1
Gray, CE1
Beastall, GH1
John, R1
Evans, PE1
Scanlon, MF1
Hall, R1

Reviews

4 reviews available for triiodothyronine and Disease

ArticleYear
[Changes in thyroid tests in non-thyroid diseases].
    Le Journal medical libanais. The Lebanese medical journal, 1996, Volume: 44, Issue:1

    Topics: Disease; Drug-Related Side Effects and Adverse Reactions; Humans; Hyperthyroxinemia; Thyroid Hormone

1996
Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients.
    Endocrinology and metabolism clinics of North America, 2002, Volume: 31, Issue:1

    Topics: Disease; Humans; Kinetics; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Thy

2002
Regulation of thyrotropin secretion in nonthyroidal illness.
    Journal of endocrinological investigation, 1986, Volume: 9 Suppl 4

    Topics: Disease; Humans; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine

1986
Thyroxine kinetics in nonthyroidal illnesses.
    Journal of endocrinological investigation, 1986, Volume: 9 Suppl 4

    Topics: Disease; Humans; Kinetics; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Thyroxine-Binding

1986

Other Studies

26 other studies available for triiodothyronine and Disease

ArticleYear
Triiodothyronine in the serum of patients treated with radioactive iodine.
    The Journal of clinical endocrinology and metabolism, 1955, Volume: 15, Issue:11

    Topics: Blood; Disease; Humans; Iodine; Iodine Radioisotopes; Radioisotopes; Thyroid Diseases; Thyroid Gland

1955
[Significance of serum thyroxin and triiodothyronine determination in clinical diagnostics].
    Orvosi hetilap, 1956, Oct-07, Volume: 97, Issue:41

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronin

1956
[Significance of serum thyroxin and triiodothyronine determination in clinical diagnostics].
    Orvosi hetilap, 1956, Oct-07, Volume: 97, Issue:41

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronin

1956
[Significance of serum thyroxin and triiodothyronine determination in clinical diagnostics].
    Orvosi hetilap, 1956, Oct-07, Volume: 97, Issue:41

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronin

1956
[Significance of serum thyroxin and triiodothyronine determination in clinical diagnostics].
    Orvosi hetilap, 1956, Oct-07, Volume: 97, Issue:41

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronin

1956
Enhancement by triodothyronine of response to corticotrophin in anterior hypopituitarism.
    The Journal of endocrinology, 1957, Volume: 15, Issue:3

    Topics: Adrenocorticotropic Hormone; Disease; Humans; Hypopituitarism; Pituitary Gland; Pituitary Gland, Ant

1957
The clinical applications of triiodothyronine.
    British medical journal, 1957, Nov-02, Volume: 2, Issue:5052

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Gland; Triiodothyronine

1957
[Diagnostic value of the triiodothyronine inhibition test].
    Klinische Wochenschrift, 1958, Jan-01, Volume: 36, Issue:1

    Topics: Disease; Humans; Serologic Tests; Thyroid Diseases; Thyroid Gland; Triiodothyronine

1958
[Triiodothyronine and triiodothyreoacetic acid in diagnosis and therapy, especially of thyroid gland diseases].
    Deutsches medizinisches Journal, 1958, Volume: 9, Issue:8

    Topics: Disease; Humans; Thyroid Diseases; Thyroid Gland; Triiodothyronine

1958
Thyroidstimulating hormone and triiodothyronine as aids in the diagnosis of thyroid disorders.
    Australasian annals of medicine, 1960, Volume: 9

    Topics: Disease; Hormones; Humans; Thyroid Diseases; Thyroid Gland; Thyrotropin; Thyrotropin-Releasing Hormo

1960
The in vitro resin sponge uptake of triiodothyronine-I-131 from serum in thyroid disease and in pregnancy.
    The Journal of clinical endocrinology and metabolism, 1960, Volume: 20

    Topics: Animals; Disease; Female; Humans; In Vitro Techniques; Porifera; Pregnancy; Radiopharmaceuticals; Th

1960
[Diagnostic value of radiotriiodothyronine uptake by erythrocytes].
    Revista medica de Chile, 1962, Volume: 90

    Topics: Disease; Erythrocytes; Radiometry; Thyroid Diseases; Thyroid Gland; Triiodothyronine

1962
Physiological or adaptive alterations in the deiodination of thyroxine.
    Hormone and metabolic research. Supplement series, 1984, Volume: 14

    Topics: Acclimatization; Disease; Fasting; Female; Fetus; Humans; Infant, Newborn; Kinetics; Obesity; Pregna

1984
Altered hormonal activity in severely ill patients after injury or sepsis.
    Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:10

    Topics: Adolescent; Adult; Aged; Disease; Hormones; Humans; Intensive Care Units; Middle Aged; Prognosis; Ra

1984
The case for "routine" screening of thyroid function.
    The Journal of the Florida Medical Association, 1980, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cost-Benefit Analysis; Disease; Female; Humans; In

1980
Thyroxine-binding globulin concentrations in the plasma of severely ill patients.
    Clinical chemistry, 1980, Volume: 26, Issue:13

    Topics: Acute Disease; Disease; Humans; Serum Globulins; Thyroxine; Thyroxine-Binding Proteins; Triiodothyro

1980
Free thyroxine by solid phase radioimmunoassay: improvement in the laboratory diagnosis of thyroid status in severely ill patients.
    Clinica chimica acta; international journal of clinical chemistry, 1982, Feb-05, Volume: 118, Issue:2-3

    Topics: Adult; Aged; Disease; Female; Humans; Male; Middle Aged; Radioimmunoassay; Reagent Kits, Diagnostic;

1982
Factors altering thyroid hormone metabolism.
    Environmental health perspectives, 1981, Volume: 38

    Topics: Age Factors; Aged; Animals; Disease; Female; Fetus; Humans; Pharmacology; Pregnancy; Thyroid Gland;

1981
Patterns of 3,3',5'-triiodothyronine monodeiodination in hypothyroidism and nonthyroid illnesses.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:2

    Topics: Adult; Diiodothyronines; Disease; Female; Humans; Hypothyroidism; Kinetics; Male; Middle Aged; Refer

1980
Impaired thyroxine and 3,5,3'-triiodothyronine handling by rat hepatocytes in the presence of serum of patients with nonthyroidal illness.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:8

    Topics: Animals; Cells, Cultured; Culture Media; Disease; Humans; Hyperthyroidism; Hypothyroidism; Liver; Ma

1995
Analogous effects of serum lipids from patients with nonthyroidal illness and normal subjects on the uptake of thyroxine and its conversion to triiodothyronine by rat hepatocytes in culture.
    The Clinical investigator, 1993, Volume: 71, Issue:1

    Topics: Animals; Biological Transport; Blood Proteins; Cells, Cultured; Disease; Fatty Acids; Lipids; Liver;

1993
[Serum thyroid hormone disorders in general diseases].
    La Revue de medecine interne, 1999, Volume: 20 Suppl 1

    Topics: Disease; Euthyroid Sick Syndromes; Humans; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronin

1999
Low serum triiodothyronine and high serum reverse triiodothyronine in old age: an effect of disease not age.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:5

    Topics: Adolescent; Adult; Aged; Aging; Disease; Female; Humans; Male; Thyrotropin; Thyroxine; Triiodothyron

1978
[The euthyreotic hypotriiodothyroninemia].
    Schweizerische medizinische Wochenschrift, 1975, Dec-13, Volume: 105, Issue:50

    Topics: Disease; Humans; Thyrotropin; Thyroxine; Triiodothyronine

1975
American Thyroid Association assessment of current free thyroid hormone and thyrotropin measurements and guidelines for future clinical assays. The Committee on Nomenclature of the American Thyroid Association.
    Clinical chemistry, 1991, Volume: 37, Issue:11

    Topics: Chemistry, Clinical; Disease; Humans; Immunoassay; Laboratories; Reagent Kits, Diagnostic; Thyroid D

1991
[Euthyroid sick syndrome].
    Schweizerische medizinische Wochenschrift, 1986, Feb-08, Volume: 116, Issue:6

    Topics: Diagnosis, Differential; Disease; Humans; Hyperthyroidism; Hypothyroidism; Thyroid Hormones; Thyrotr

1986
Normal free thyroxine in critical nonthyroidal illnesses measured by ultrafiltration of undiluted serum and equilibrium dialysis.
    The Journal of clinical endocrinology and metabolism, 1988, Volume: 67, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Chromatography, Paper; Dialysis; Disease; Female; Humans; Hyperthyro

1988
Male hypogonadism--a non-specific consequence of illness.
    The Quarterly journal of medicine, 1987, Volume: 64, Issue:243

    Topics: Adolescent; Adult; Aged; Disease; Humans; Luteinizing Hormone; Male; Middle Aged; Testosterone; Trii

1987
Clinical value of immunoradiometric assay of thyrotropin for patients with nonthyroidal illness and taking various drugs.
    Clinical chemistry, 1987, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diagnostic Tests, Routine; Disease; Drug Therapy; Female

1987