triiodothyronine has been researched along with Diabetes Mellitus, Type 2 in 78 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
Excerpt | Relevance | Reference |
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" Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 9.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
"The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 8.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
"We demonstrated positive associations of thyroid hormones with prevalent and incident type 2 diabetes mellitus suggesting that hyperthyroxinemia may contribute to the pathogenesis of this condition." | 7.88 | Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark. ( Dörr, M; Ittermann, T; Jørgensen, T; Markus, MRP; Schipf, S; Thuesen, BH; Völzke, H, 2018) |
"Free triiodothyronine (FT3) is an independent risk factor for nonalcoholic fatty liver disease (NAFLD) in patients with euthyroid." | 5.62 | Free Triiodothyronine Is Independently Associated with Nonalcoholic Fatty Liver Disease in Hospitalized Type 2 Diabetes Mellitus Patients. ( Chen, Y; Hong, Y; Li, S; Lin, C; Shi, R; Xia, X; Xiu, L, 2021) |
"Free triiodothyronine (FT3) levels were lower in the T2DM group compared with the nondiabetes group (P = 0." | 5.42 | Free triiodothyronine levels and short-term prognosis in chronic heart failure patients with type 2 diabetes. ( Chen, P; Lei, X; Li, S; Liu, Z; Luo, Y; Wu, D; Xu, D, 2015) |
" Objective To prospectively evaluate if administration of metformin to obese, diabetic patients with primary hypothyroidism on stable thyroxine replacement doses modifies TSH levels." | 5.12 | Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy. ( Cordido, F; Isidro, ML; Nemiña, R; Penín, MA, 2007) |
" During pregnancy, mildly elevated maternal free thyroxine levels less than 20% above the upper limit may not be harmful to unaffected fetuses." | 4.98 | Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature. ( Guan, H; Guo, H; Guo, R; Li, Y; Shan, Z; Wu, D, 2018) |
"The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group." | 4.12 | Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes. ( Gong, L; Liang, K; Liu, J; Ma, A; Yin, X, 2022) |
"Treatment of hypothyroidism involves the endogenous conversion of thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and may not be optimal in some cases when based on T4 alone." | 3.91 | Cognitive function in hypothyroidism: what is that deiodinase again? ( Hernandez, A, 2019) |
"We demonstrated positive associations of thyroid hormones with prevalent and incident type 2 diabetes mellitus suggesting that hyperthyroxinemia may contribute to the pathogenesis of this condition." | 3.88 | Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark. ( Dörr, M; Ittermann, T; Jørgensen, T; Markus, MRP; Schipf, S; Thuesen, BH; Völzke, H, 2018) |
"The objective of the study was to describe the clinical and biochemical findings of four patients with chronic hypothyroidism, previously euthyroid on fixed doses of L-T4 for several years, in whom the metformin was initiated." | 3.73 | Thyrotropin suppression by metformin. ( Filmore-Nassar, A; Glass, AR; Vigersky, RA, 2006) |
"It is frequently preceded by gestational diabetes." | 2.67 | Reduced postprandial energy expenditure in women predisposed to type 2 diabetes. ( Anyaoku, V; Beard, RW; Elkeles, RS; Johnston, DG; Niththyananthan, R; Robinson, S, 1994) |
"A key phenotype associated with type 2 diabetes in humans is impaired mitochondrial oxidative metabolism in skeletal muscle, a pattern potentially contributing to increased lipid accumulation and impaired metabolic flexibility-in turn, central features of both insulin resistance and diabetes." | 2.44 | Links between thyroid hormone action, oxidative metabolism, and diabetes risk? ( Crunkhorn, S; Patti, ME, 2008) |
"41." | 1.91 | Free triiodothyronine predicts the risk of developing diabetic kidney disease. ( Duan, P; Hu, W; Jiang, S; Li, S; Li, W; Tu, P; Wan, Z; Yang, Z, 2023) |
"Graves disease (GD) and type 2 diabetes mellitus (T2DM) both impair liver function; we therefore explored the possibility of a relationship among diabetic control, thyroid function, and liver function." | 1.72 | Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan. ( Hsieh, YS; Hsu, CH; Huang, CL; Lee, YW; Lin, YP; Lin, YY; Weng, SF, 2022) |
"The severity of liver fibrosis is an important predictor of death in patients with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM)." | 1.72 | The correlation between triiodothyronine and the severity of liver fibrosis. ( He, W; Huang, C; Huang, P; Huang, Y; Li, X; Lin, M; Shi, X; Su, W; Wang, L; Wang, S; Zhang, X; Zhao, Y, 2022) |
"Free triiodothyronine (FT3) is an independent risk factor for nonalcoholic fatty liver disease (NAFLD) in patients with euthyroid." | 1.62 | Free Triiodothyronine Is Independently Associated with Nonalcoholic Fatty Liver Disease in Hospitalized Type 2 Diabetes Mellitus Patients. ( Chen, Y; Hong, Y; Li, S; Lin, C; Shi, R; Xia, X; Xiu, L, 2021) |
"Thyroid dysfunction and gestational diabetes (GDM) are the two most common endocrine disorders that can be observed during pregnancy." | 1.62 | The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus. ( Kamenov, Z; Yanachkova, V, 2021) |
"Thyroid function and type 2 diabetes mellitus (T2DM) are both associated with increased risks of adverse clinical outcomes in nonalcoholic fatty liver disease (NAFLD)." | 1.56 | Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients. ( Huang, B; Yang, S; Ye, S, 2020) |
"Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA)." | 1.51 | Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus. ( Anothaisintawee, T; Chailurkit, LO; Chirakalwasan, N; Manodpitipong, A; Nimitphong, H; Pinyopodjanard, S; Reutrakul, S; Saetang, S; Siwasaranond, N; Sriphrapradang, C; Suntornlohanakul, O, 2019) |
"He had a history of thyroid cancer but did not have diabetes mellitus." | 1.51 | Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report. ( Kim, EY; Kim, JJ, 2019) |
"Type 2 diabetes has an underlying pathology with thyroid dysfunction." | 1.48 | The Association Between the Levels of Thyroid Hormones and Peripheral Nerve Conduction in Patients with Type 2 Diabetes Mellitus. ( Yang, LZ; Zhu, FF, 2018) |
"Effectively treating metabolic syndrome and its progression to type 2 diabetes, steatohepatitis and cardiovascular disease remain a major clinical challenge." | 1.46 | Metabolic Syndrome: One Speckled Stone Kills a Flock of Birds? ( Angelin, B; Bonde, Y, 2017) |
"Free triiodothyronine (FT3) levels were lower in the T2DM group compared with the nondiabetes group (P = 0." | 1.42 | Free triiodothyronine levels and short-term prognosis in chronic heart failure patients with type 2 diabetes. ( Chen, P; Lei, X; Li, S; Liu, Z; Luo, Y; Wu, D; Xu, D, 2015) |
"Metformin therapy was a nonsignificant variable in this model." | 1.39 | Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes. ( Díez, JJ; Iglesias, P, 2013) |
"Notably, diabetic nephropathy was accompanied by a significant decrease in PI3K activity and an increase in TGF-β1 expression in kidneys." | 1.37 | Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes. ( Lin, Y; Sun, Z, 2011) |
"Fatty liver is an important complication of obesity; however, regulatory mechanisms mediating altered gene expression patterns have not been identified." | 1.35 | Thyroid hormone-related regulation of gene expression in human fatty liver. ( Bianco, AC; Boes, T; Dearie, F; Goldfine, AB; Kim, BW; Kim, EY; Mun, E; Nasser, I; Park, PJ; Patti, ME; Pihlajamäki, J; Schroeder, J, 2009) |
"Patients with type 2 diabetes had significantly lower serum FT3 levels (p = 0." | 1.35 | A comparative study of thyroid hormone levels in diabetic and non-diabetic patients. ( Alam, NH; Islam, S; Khan, SA; Yesmine, S, 2008) |
"Rosiglitazone was administered to dexamethasone-induced hyperglycaemic male mice and the alterations in serum concentrations of thyroid hormones insulin, total cholesterol, triglycerides and fasting glucose were studied." | 1.34 | Amelioration of corticosteroid-induced type 2 diabetes mellitus by rosiglitazone is possibly mediated through stimulation of thyroid function and inhibition of tissue lipid peroxidation in mice. ( Jatwa, R; Kar, A; Panda, S; Parmar, HS, 2007) |
"Patients with type 2 diabetes (DM) demonstrate inadequate insulin release, elevated gluconeogenesis, and diminished nonoxidative glucose disposal." | 1.31 | Type 2 diabetic patients may have a mild form of an injury response: a clinical research center study. ( Richardson, AP; Tayek, JA, 2002) |
"Elderly men with NIDDM had even lower serum testosterone levels compared with elderly men without NIDDM." | 1.29 | Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity. ( Chang, TC; Hsiao, YL; Tung, CC, 1994) |
"Examination of cells from patients with NIDDM revealed an increased thyroid hormone induced glucose uptake, indicating increased thyroid hormone sensitivity." | 1.28 | Thyroid hormone stimulated glucose uptake in human mononuclear blood cells from normal persons and from patients with non-insulin-dependent diabetes mellitus. ( Kvetny, J; Matzen, L, 1989) |
"Hyperthyroidism is known to further impair carbohydrate metabolism in diabetic patients." | 1.27 | Glucose metabolism in noninsulin-dependent diabetic patients with experimental hyperthyroidism. ( Bratusch-Marrain, PR; Komjati, M; Waldhäusl, WK, 1985) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (10.26) | 18.7374 |
1990's | 8 (10.26) | 18.2507 |
2000's | 16 (20.51) | 29.6817 |
2010's | 25 (32.05) | 24.3611 |
2020's | 21 (26.92) | 2.80 |
Authors | Studies |
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Li, P | 1 |
Ding, L | 1 |
Zhen, J | 1 |
Hu, J | 1 |
Fan, Y | 1 |
Liu, M | 1 |
Sun, X | 1 |
Chen, L | 1 |
Wu, R | 1 |
Zhang, D | 1 |
He, Y | 1 |
Gong, L | 1 |
Ma, A | 1 |
Yin, X | 1 |
Liang, K | 1 |
Liu, J | 2 |
Lee, YW | 1 |
Lin, YY | 1 |
Weng, SF | 1 |
Hsu, CH | 1 |
Huang, CL | 1 |
Lin, YP | 1 |
Hsieh, YS | 1 |
He, W | 2 |
Huang, C | 2 |
Wang, L | 2 |
Su, W | 2 |
Wang, S | 3 |
Huang, P | 2 |
Zhang, X | 3 |
Huang, Y | 3 |
Zhao, Y | 2 |
Lin, M | 2 |
Shi, X | 2 |
Li, X | 2 |
Okada, S | 2 |
Isoda, A | 2 |
Hoshi, H | 2 |
Okada, J | 2 |
Okada, K | 2 |
Yamada, E | 2 |
Saito, T | 2 |
Watanabe, T | 2 |
Kikkawa, K | 1 |
Ohshima, K | 2 |
Deng, Y | 1 |
Han, Y | 1 |
Gao, S | 1 |
Dong, W | 1 |
Yu, Y | 1 |
Lin, L | 1 |
Du, Y | 1 |
Niu, G | 1 |
Xia, S | 1 |
Zhao, X | 1 |
Sun, J | 1 |
Xu, X | 1 |
Xin, S | 1 |
Li, W | 1 |
Yang, Z | 1 |
Li, S | 3 |
Jiang, S | 1 |
Hu, W | 1 |
Wan, Z | 1 |
Tu, P | 1 |
Duan, P | 1 |
Amirabadizadeh, A | 1 |
Amouzegar, A | 1 |
Mehran, L | 1 |
Azizi, F | 1 |
Panveloski-Costa, AC | 1 |
Kuwabara, WMT | 1 |
Munhoz, AC | 1 |
Lucena, CF | 1 |
Curi, R | 1 |
Carpinelli, AR | 1 |
Nunes, MT | 1 |
Li, Q | 2 |
Lu, M | 1 |
Wang, NJ | 1 |
Chen, Y | 2 |
Chen, YC | 1 |
Han, B | 1 |
Xia, FZ | 1 |
Jiang, BR | 1 |
Zhai, HL | 1 |
Lin, DP | 1 |
Lu, YL | 1 |
Xiu, S | 1 |
Mu, Z | 1 |
Zhao, L | 1 |
Sun, L | 1 |
Zhang, T | 1 |
Shi, J | 1 |
Peng, Y | 2 |
Mu, Q | 1 |
Fang, Q | 1 |
Gu, W | 1 |
Hong, J | 1 |
Zhang, Y | 1 |
Wang, W | 1 |
Huang, B | 1 |
Yang, S | 1 |
Ye, S | 1 |
Gu, L | 1 |
Yang, J | 1 |
Gong, Y | 1 |
Ma, Y | 1 |
Yan, S | 1 |
Wang, Y | 1 |
Shi, R | 1 |
Lin, C | 1 |
Hong, Y | 1 |
Xia, X | 1 |
Xiu, L | 1 |
Yanachkova, V | 1 |
Kamenov, Z | 1 |
Stedman, M | 1 |
Taylor, P | 1 |
Premawardhana, L | 1 |
Okosieme, O | 1 |
Dayan, C | 1 |
Heald, AH | 1 |
Nakajima, Y | 1 |
Ozawa, A | 1 |
Yamada, M | 1 |
Ittermann, T | 1 |
Schipf, S | 1 |
Dörr, M | 1 |
Thuesen, BH | 1 |
Jørgensen, T | 1 |
Völzke, H | 1 |
Markus, MRP | 1 |
Kamrul-Hasan, M | 1 |
Siddiqui, NI | 1 |
Shubha, RA | 1 |
Abu-Bakar, M | 1 |
Chanda, PK | 1 |
Haque, FI | 1 |
Zhu, FF | 1 |
Yang, LZ | 1 |
Sriphrapradang, C | 1 |
Pinyopodjanard, S | 1 |
Suntornlohanakul, O | 1 |
Nimitphong, H | 1 |
Chirakalwasan, N | 1 |
Saetang, S | 1 |
Anothaisintawee, T | 1 |
Siwasaranond, N | 1 |
Manodpitipong, A | 1 |
Chailurkit, LO | 1 |
Reutrakul, S | 1 |
Hernandez, A | 1 |
Wu, D | 2 |
Guo, R | 1 |
Guo, H | 1 |
Li, Y | 1 |
Guan, H | 1 |
Shan, Z | 1 |
Kim, JJ | 1 |
Kim, EY | 2 |
Wang, YM | 1 |
Ling, Y | 1 |
Gao, X | 1 |
Jorde, R | 1 |
Schirmer, H | 1 |
Wilsgaard, T | 1 |
Joakimsen, RM | 1 |
Mathiesen, EB | 1 |
Njølstad, I | 1 |
Løchen, ML | 1 |
Figenschau, Y | 1 |
Svartberg, J | 1 |
Hutchinson, MS | 1 |
Kjærgaard, M | 1 |
Jørgensen, L | 1 |
Grimnes, G | 1 |
Di Crescenzo, V | 1 |
D'Antonio, A | 1 |
Tonacchera, M | 1 |
Carlomagno, C | 1 |
Vitale, M | 1 |
Jing, S | 1 |
Xiaoying, D | 1 |
Ying, X | 1 |
Rui, L | 1 |
Mingyu, G | 1 |
Yuting, C | 1 |
Yanhua, Y | 1 |
Yufan, W | 1 |
Haiyan, S | 1 |
Yongde, P | 1 |
Bollinger, SS | 1 |
Weltman, NY | 1 |
Gerdes, AM | 1 |
Schlenker, EH | 1 |
Krysiak, R | 1 |
Szkrobka, W | 1 |
Okopien, B | 1 |
van Tienhoven-Wind, L | 1 |
Dullaart, RP | 1 |
Chen, P | 1 |
Lei, X | 1 |
Liu, Z | 1 |
Luo, Y | 1 |
Xu, D | 1 |
Finan, B | 1 |
Clemmensen, C | 1 |
Zhu, Z | 1 |
Stemmer, K | 1 |
Gauthier, K | 1 |
Müller, L | 1 |
De Angelis, M | 1 |
Moreth, K | 1 |
Neff, F | 1 |
Perez-Tilve, D | 1 |
Fischer, K | 1 |
Lutter, D | 1 |
Sánchez-Garrido, MA | 1 |
Liu, P | 1 |
Tuckermann, J | 1 |
Malehmir, M | 1 |
Healy, ME | 1 |
Weber, A | 1 |
Heikenwalder, M | 1 |
Jastroch, M | 1 |
Kleinert, M | 1 |
Jall, S | 1 |
Brandt, S | 1 |
Flamant, F | 1 |
Schramm, KW | 1 |
Biebermann, H | 1 |
Döring, Y | 1 |
Weber, C | 1 |
Habegger, KM | 1 |
Keuper, M | 1 |
Gelfanov, V | 1 |
Liu, F | 1 |
Köhrle, J | 1 |
Rozman, J | 1 |
Fuchs, H | 1 |
Gailus-Durner, V | 1 |
Hrabě de Angelis, M | 1 |
Hofmann, SM | 1 |
Yang, B | 1 |
Tschöp, MH | 1 |
DiMarchi, R | 1 |
Müller, TD | 1 |
Jun, JE | 1 |
Jee, JH | 1 |
Bae, JC | 1 |
Jin, SM | 1 |
Hur, KY | 1 |
Lee, MK | 1 |
Kim, TH | 1 |
Kim, SW | 1 |
Kim, JH | 1 |
Gu, Y | 1 |
Li, H | 1 |
Bao, X | 1 |
Zhang, Q | 1 |
Liu, L | 1 |
Meng, G | 1 |
Wu, H | 1 |
Du, H | 1 |
Shi, H | 1 |
Xia, Y | 1 |
Su, Q | 1 |
Fang, L | 1 |
Yu, F | 1 |
Yang, H | 1 |
Yu, B | 1 |
Sun, S | 1 |
Wang, X | 1 |
Zhou, M | 1 |
Jia, Q | 1 |
Guo, Q | 1 |
Chang, H | 1 |
Wang, G | 1 |
Huang, G | 1 |
Song, K | 1 |
Niu, K | 1 |
Bonde, Y | 1 |
Angelin, B | 1 |
Islam, S | 2 |
Yesmine, S | 1 |
Khan, SA | 1 |
Alam, NH | 1 |
Jatwa, R | 2 |
Kar, A | 2 |
Pihlajamäki, J | 1 |
Boes, T | 1 |
Dearie, F | 1 |
Kim, BW | 1 |
Schroeder, J | 1 |
Mun, E | 1 |
Nasser, I | 1 |
Park, PJ | 1 |
Bianco, AC | 1 |
Goldfine, AB | 1 |
Patti, ME | 2 |
Naziroğlu, M | 1 |
Simşek, M | 1 |
Lin, Y | 2 |
Sun, Z | 2 |
Lambadiari, V | 1 |
Mitrou, P | 1 |
Maratou, E | 1 |
Raptis, AE | 1 |
Tountas, N | 1 |
Raptis, SA | 1 |
Dimitriadis, G | 1 |
Taneichi, H | 1 |
Sasai, T | 1 |
Ohara, M | 1 |
Honma, H | 1 |
Nagasawa, K | 1 |
Takahashi, T | 1 |
Ishii, M | 1 |
Fujiwara, F | 1 |
Yamashina, M | 1 |
Kajiwara, T | 1 |
Takabe, N | 1 |
Takahashi, K | 1 |
Satoh, J | 1 |
Díez, JJ | 1 |
Iglesias, P | 1 |
Anthonsen, S | 1 |
Larsen, J | 1 |
Pedersen, PL | 1 |
Dalgaard, LT | 1 |
Kvetny, J | 2 |
Kim, SR | 2 |
Talbott, EO | 1 |
Tull, ES | 1 |
Zborowski, JV | 1 |
Vogt, MT | 1 |
Kuller, LH | 2 |
Jin, ES | 1 |
Burgess, SC | 1 |
Merritt, ME | 1 |
Sherry, AD | 1 |
Malloy, CR | 1 |
Pedersen, SB | 1 |
Nyholm, B | 1 |
Kristensen, K | 1 |
Nielsen, MF | 1 |
Schmitz, O | 1 |
Richelsen, B | 1 |
Vigersky, RA | 1 |
Filmore-Nassar, A | 1 |
Glass, AR | 1 |
Nuttall, FQ | 1 |
Gannon, MC | 1 |
Rameshwar, J | 1 |
Anand, K | 1 |
Ferguson, DC | 1 |
Caffall, Z | 1 |
Hoenig, M | 1 |
Parmar, HS | 1 |
Panda, S | 1 |
Isidro, ML | 1 |
Penín, MA | 1 |
Nemiña, R | 1 |
Cordido, F | 1 |
Crunkhorn, S | 1 |
Kabadi, UM | 2 |
Premachandra, BN | 1 |
Celani, MF | 1 |
Bonati, ME | 1 |
Stucci, N | 1 |
Robinson, S | 1 |
Niththyananthan, R | 1 |
Anyaoku, V | 1 |
Elkeles, RS | 1 |
Beard, RW | 1 |
Johnston, DG | 1 |
Chang, TC | 1 |
Tung, CC | 1 |
Hsiao, YL | 1 |
Lu, G | 1 |
Torrance, CJ | 1 |
Devente, JE | 1 |
Jones, JP | 1 |
Dohm, GL | 1 |
Shimokawa, T | 1 |
Kato, M | 1 |
Shioduka, K | 1 |
Irie, J | 1 |
Ezaki, O | 1 |
Koh, H | 1 |
Tsushima, M | 1 |
Harano, Y | 1 |
Talbott, EA | 1 |
Tull, E | 1 |
Vogt, M | 1 |
Andersen, SJ | 1 |
Richardson, AP | 1 |
Tayek, JA | 1 |
Yamagishi, S | 1 |
Miyakoshi, H | 1 |
Nagai, Y | 1 |
Ohsawa, K | 1 |
Kobayashi, K | 1 |
Matzen, L | 1 |
Bagchi, N | 1 |
Palaniswami, N | 1 |
Desai, H | 1 |
Felicetta, J | 1 |
Brown, TR | 1 |
Bhu, N | 1 |
Meena, HS | 1 |
Lean, ME | 1 |
Murgatroyd, PR | 1 |
Rothnie, I | 1 |
Reid, IW | 1 |
Harvey, R | 1 |
Bratusch-Marrain, PR | 1 |
Komjati, M | 1 |
Waldhäusl, WK | 1 |
Zamora Madaria, E | 1 |
Barba Chacón, A | 1 |
Mangas Rojas, A | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effects of 4-month Therapy of Levothyroxine on Non-Alcoholic Fatty Liver Disease (NAFLD) and Diabetes Control in Diabetic Patients[NCT03281083] | Phase 2 | 29 participants (Actual) | Interventional | 2014-03-28 | Terminated (stopped due to Difficult recruitment and end of funding.) | ||
The Effect of Ingestion of Foods on the Plasma Glucose and Insulin Response in Subjects With Type 2 Diabetes: Protein, Amino Acids & Insulin & Glucagon Secretion in Humans[NCT01471509] | 300 participants (Anticipated) | Interventional | 1982-08-31 | Suspended (stopped due to Lack of funding) | |||
Energy Balance Following Islet Transplantation[NCT03063229] | 2 participants (Actual) | Interventional | 2016-06-30 | Terminated (stopped due to Unable to recruit participants due to lack of patients eligible at the time) | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
4 reviews available for triiodothyronine and Diabetes Mellitus, Type 2
Article | Year |
---|---|
The Physiological Functions and Polymorphisms of Type II Deiodinase.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Iodide Peroxidase; Polymorphism, Genetic; Syndrome; Triiod | 2023 |
The effect of metformin therapy on serum thyrotropin and free thyroxine concentrations in patients with type 2 diabetes: a meta-analysis.
Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Metformin; Thyroid Hormones; T | 2023 |
Resistance to thyroid hormone β in autoimmune thyroid disease: a case report and review of literature.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Humans; Hypothyroidism; Mutation; Postp | 2018 |
Links between thyroid hormone action, oxidative metabolism, and diabetes risk?
Topics: Animals; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Gene Expression Regulation; Humans; Iodide P | 2008 |
6 trials available for triiodothyronine and Diabetes Mellitus, Type 2
Article | Year |
---|---|
Effects of hormone replacement therapy with vitamin C and E supplementation on plasma thyroid hormone levels in postmenopausal women with Type 2 diabetes.
Topics: Aged; Antioxidants; Ascorbic Acid; Diabetes Mellitus, Type 2; Female; Hormone Replacement Therapy; H | 2009 |
Basal and T₃-induced ROS production in lymphocyte mitochondria is increased in type 2 diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Lymphocytes; Male; Membrane Potential, Mitochondri | 2013 |
The metabolic response to a high-protein, low-carbohydrate diet in men with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Aldosterone; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet | 2006 |
Metformin reduces thyrotropin levels in obese, diabetic women with primary hypothyroidism on thyroxine replacement therapy.
Topics: Aged; Body Weight; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agen | 2007 |
Reduced postprandial energy expenditure in women predisposed to type 2 diabetes.
Topics: Adult; Blood Glucose; Body Temperature Regulation; Diabetes Mellitus, Type 2; Diabetes, Gestational; | 1994 |
Effect of carbohydrate intake on serum 3,5,3'-triiodothyronine-response to glucose ingestion and its relation to glucose tolerance in lean non-insulin-dependent diabetic patients.
Topics: Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Energy Intake; Fem | 1999 |
68 other studies available for triiodothyronine and Diabetes Mellitus, Type 2
Article | Year |
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Association of subtle alterations in thyroid function with presarcopenia in patients with type 2 diabetes mellitus.
Topics: Adult; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Hyperthyroidism; Hypothyroidism; | 2022 |
Association of thyroid hormone with body fat content and lipid metabolism in euthyroid male patients with type 2 diabetes mellitus: a cross-sectional study.
Topics: Adipose Tissue; Adult; Body Mass Index; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; | 2021 |
Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes.
Topics: C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Humans; Obesity; Thyroid Function Tes | 2022 |
Clinical significance of hepatic function in Graves disease with type 2 diabetic mellitus: A single-center retrospective cross-sectional study in Taiwan.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Cross-Sectional Studies; Diabetes Mel | 2022 |
The correlation between triiodothyronine and the severity of liver fibrosis.
Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Liver Cirrhosis; Membrane Glycoproteins | 2022 |
The correlation between triiodothyronine and the severity of liver fibrosis.
Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Liver Cirrhosis; Membrane Glycoproteins | 2022 |
The correlation between triiodothyronine and the severity of liver fibrosis.
Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Liver Cirrhosis; Membrane Glycoproteins | 2022 |
The correlation between triiodothyronine and the severity of liver fibrosis.
Topics: Animals; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Liver Cirrhosis; Membrane Glycoproteins | 2022 |
The ratio of free triiodothyronine to free thyroxine is regulated differently in patients with type 2 diabetes mellitus treated and not treated with sodium glucose cotransporter 2 inhibitors.
Topics: Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Retrospective Studies; Sodium-Gl | 2023 |
Folate deficiency may increase the risk for elevated TSH in patients with type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Folic Acid; Humans; Thyroid Diseases; Thyroid Hormones; Thyrotropin; Thyr | 2023 |
The effect of Central and peripheral thyroid resistance indices on diabetic retinopathy: a study of hospitalized euthyroid patients with T2DM in China.
Topics: Adult; Aged; China; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Retinal Diseases; | 2023 |
Free triiodothyronine predicts the risk of developing diabetic kidney disease.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; R | 2023 |
The insulin resistance is reversed by exogenous 3,5,3'triiodothyronine in type 2 diabetic Goto-Kakizaki rats by an inflammatory-independent pathway.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin; Insulin Resistance; Mu | 2020 |
Relationship between Free Thyroxine and Islet Beta-cell Function in Euthyroid Subjects.
Topics: Adult; Aged; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter, Nodular; Humans; In | 2020 |
Low free triiodothyronine levels are associated with risk of frailty in older adults with type 2 diabetes mellitus.
Topics: Aged; Diabetes Mellitus, Type 2; Frailty; Hand Strength; Humans; Thyroid Function Tests; Thyrotropin | 2020 |
Sex-influenced association between free triiodothyronine levels and poor glycemic control in euthyroid patients with type 2 diabetes mellitus.
Topics: Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycemic Control; H | 2020 |
Association between Thyroid Function and Nonalcoholic Fatty Liver Disease in Euthyroid Type 2 Diabetes Patients.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Male; Middle Aged; Non-a | 2020 |
Lower free thyroid hormone levels are associated with high blood glucose and insulin resistance; these normalize with metabolic improvement of type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Cross-Sectional Studies; Diabet | 2021 |
Free Triiodothyronine Is Independently Associated with Nonalcoholic Fatty Liver Disease in Hospitalized Type 2 Diabetes Mellitus Patients.
Topics: Adult; Aged; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Hospitalization; Hum | 2021 |
The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; Retrospective Studies; | 2021 |
Liothyronine and levothyroxine prescribing in England: A comprehensive survey and evaluation.
Topics: Diabetes Mellitus, Type 2; Female; General Practice; Hormone Replacement Therapy; Humans; Practice P | 2021 |
Free triiodothyronine /free thyroxine ratio as an index of deiodinase type 1 and 2 activities negatively correlates with casual serum insulin levels in patients with type 2 diabetes mellitus.
Topics: Aged; Aged, 80 and over; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Huma | 2021 |
Hyperthyroxinemia is positively associated with prevalent and incident type 2 diabetes mellitus in two population-based samples from Northeast Germany and Denmark.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Denmark; Diabetes Mellitus, Type 2; Female; German | 2018 |
Low Free T₃ was Associated with Poor Glycemic Control in Type 2 Diabetes in a Hospital Based Study in Bangladesh.
Topics: Adult; Bangladesh; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia | 2018 |
The Association Between the Levels of Thyroid Hormones and Peripheral Nerve Conduction in Patients with Type 2 Diabetes Mellitus.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Electromyography; Female; Humans; Male; Midd | 2018 |
Lack of associations between thyroid function and obstructive sleep apnea severity in adults with prediabetes and diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Hypothyroidism; Male; Middle Aged; Prediabetic Sta | 2019 |
Cognitive function in hypothyroidism: what is that deiodinase again?
Topics: Brain; Cognition; Diabetes Mellitus, Type 2; Humans; Hypothyroidism; Iodide Peroxidase; Thyroxine; T | 2019 |
Myxedema coma precipitated by diabetic ketoacidosis after total thyroidectomy: a case report.
Topics: Adult; Blood Gas Analysis; Coma; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Glycated Hemoglob | 2019 |
[Effects of thyroid hormone on islet β cell function among type 2 diabetics with normal thyroid function].
Topics: Diabetes Mellitus, Type 2; Female; Humans; Islets of Langerhans; Male; Middle Aged; Risk Factors; Th | 2013 |
The phosphodiesterase 8B gene rs4704397 is associated with thyroid function, risk of myocardial infarction, and body height: the Tromsø study.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adult; Aged; Body Height; Cardiovascular Diseases; Diabetes Mel | 2014 |
Human herpes virus associated with Hashimoto's thyroiditis.
Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Hashimoto Disease; Herpes Labialis; Humans; Im | 2013 |
Different levels of thyroid hormones between impaired fasting glucose and impaired glucose tolerance: free T3 affects the prevalence of impaired fasting glucose and impaired glucose tolerance in opposite ways.
Topics: Aged; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Tolerance T | 2014 |
T3 supplementation affects ventilatory timing & glucose levels in type 2 diabetes mellitus model.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Pulmonar | 2015 |
The effect of metformin on the hypothalamic-pituitary-thyroid axis in patients with type 2 diabetes and subclinical hyperthyroidism.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperthyroidism; Hypogl | 2015 |
Low normal thyroid function as a determinant of increased large very low density lipoprotein particles.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Lipoproteins, VLDL; Male; Middle Aged; Thyroid Func | 2015 |
Free triiodothyronine levels and short-term prognosis in chronic heart failure patients with type 2 diabetes.
Topics: Aged; Chronic Disease; Diabetes Mellitus, Type 2; Echocardiography; Female; Heart Failure; Humans; M | 2015 |
Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease.
Topics: Animals; Atherosclerosis; Body Weight; Bone and Bones; Chemical Engineering; Cholesterol; Diabetes M | 2016 |
Association Between Changes in Thyroid Hormones and Incident Type 2 Diabetes: A Seven-Year Longitudinal Study.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Humans; Incidence; Longitudinal Studies; Male; Middle Aged | 2017 |
The Relationship Between Thyroid Function and the Prevalence of Type 2 Diabetes Mellitus in Euthyroid Subjects.
Topics: Adult; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; | 2017 |
Metabolic Syndrome: One Speckled Stone Kills a Flock of Birds?
Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Fatty Liver; Glucagon; Hormones; Humans | 2017 |
A comparative study of thyroid hormone levels in diabetic and non-diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Immunoenzyme Techniques | 2008 |
Amelioration of metformin-induced hypothyroidism by Withania somnifera and Bauhinia purpurea extracts in Type 2 diabetic mice.
Topics: Animals; Bauhinia; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female | 2009 |
Thyroid hormone-related regulation of gene expression in human fatty liver.
Topics: Adult; Animals; Diabetes Mellitus, Type 2; Fatty Liver; Female; Gene Expression Regulation; Heat-Sho | 2009 |
Thyroid hormone potentiates insulin signaling and attenuates hyperglycemia and insulin resistance in a mouse model of type 2 diabetes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Basic Helix-Loop-Helix Transcription Factors; Blood Glucose; Bloo | 2011 |
Thyroid hormones are positively associated with insulin resistance early in the development of type 2 diabetes.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Food; Glucose Intolerance; Humans; | 2011 |
Thyroid hormone ameliorates diabetic nephropathy in a mouse model of type II diabetes.
Topics: Albuminuria; Animals; Collagen; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic | 2011 |
Higher serum free triiodothyronine levels within the normal range are associated with metabolic syndrome components in type 2 diabetic subjects with euthyroidism.
Topics: Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypolipidemic Agents; Logistic M | 2011 |
Relationship between serum thyrotropin concentrations and metformin therapy in euthyroid patients with type 2 diabetes.
Topics: Aged; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Goiter; Huma | 2013 |
Assessment of the disturbances in metabolic homeostasis: a hypothesis of synergism.
Topics: Black or African American; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Homeostasis; Humans; I | 2002 |
Differing mechanisms of hepatic glucose overproduction in triiodothyronine-treated rats vs. Zucker diabetic fatty rats by NMR analysis of plasma glucose.
Topics: Animals; Blood Glucose; Citric Acid Cycle; Diabetes Mellitus, Type 2; Glucose; Glycerol; Glycogen; K | 2005 |
Increased adiposity and reduced adipose tissue mRNA expression of uncoupling protein-2 in first-degree relatives of type 2 diabetic patients: evidence for insulin stimulation of UCP-2 and UCP-3 gene expression in adipose tissue.
Topics: Adipose Tissue; Adult; Body Composition; Calorimetry, Indirect; Carrier Proteins; Case-Control Studi | 2005 |
Thyrotropin suppression by metformin.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Interactions; Female; Goiter; Graves D | 2006 |
Antihyperglycaemic and antiperoxidative roles of acarbose in type 2 diabetes mellitus are possibly mediated through changes in thyroid function.
Topics: Acarbose; Animals; Antioxidants; Blood Glucose; Catalase; Dexamethasone; Diabetes Mellitus, Experime | 2006 |
Obesity increases free thyroxine proportionally to nonesterified fatty acid concentrations in adult neutered female cats.
Topics: Animals; Cats; Diabetes Mellitus, Type 2; Disease Progression; Fatty Acids, Nonesterified; Female; I | 2007 |
Amelioration of corticosteroid-induced type 2 diabetes mellitus by rosiglitazone is possibly mediated through stimulation of thyroid function and inhibition of tissue lipid peroxidation in mice.
Topics: Animals; Blood Glucose; Catalase; Cholesterol; Dexamethasone; Diabetes Mellitus, Experimental; Diabe | 2007 |
Impaired pituitary thyrotroph function in uncontrolled type II diabetes mellitus: normalization on recovery.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Humans; Insulin; Male; Middle Aged; Pituitary Gland, Anter | 1984 |
Low triiodothyronine and raised reverse triiodothyronine levels in patients over fifty years of age who have type II diabetes mellitus: influence of metabolic control, not age.
Topics: Adult; Aged; Aging; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; Thyrotropin | 1984 |
Prevalence of abnormal thyrotropin concentrations measured by a sensitive assay in patients with type 2 diabetes mellitus.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Autoantibodies; Body Mass Index; Diabetes Mellitus, Typ | 1994 |
Hormonal changes in elderly men with non-insulin-dependent diabetes mellitus and the hormonal relationships to abdominal adiposity.
Topics: Abdomen; Adipose Tissue; Adult; Aged; Aging; Body Constitution; Diabetes Mellitus, Type 2; Follicle | 1994 |
[Changes in circulating lymphocyte triiodothyronine receptors in diabetes mellitus].
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Lymphocytes; Male; Middle Aged; Receptors, T | 1993 |
Effects of thyroid hormone on GLUT4 glucose transporter gene expression and NIDDM in rats.
Topics: Animals; Diabetes Mellitus, Type 2; Gene Expression; Glucose Transporter Type 4; Hindlimb; Hyperinsu | 1997 |
Effect of triiodothyronine on muscle cell differentiation and blood glucose level in hyperglycemic KK mice.
Topics: Animals; Biomarkers; Blood Glucose; Body Weight; Cell Differentiation; Diabetes Mellitus, Type 2; Gl | 1997 |
Contribution of abnormalities of thyroid hormones to type 2 diabetes.
Topics: Black People; Blood Glucose; Diabetes Mellitus, Type 2; Female; Homeostasis; Humans; Insulin; Middle | 2000 |
Type 2 diabetic patients may have a mild form of an injury response: a clinical research center study.
Topics: Acute-Phase Reaction; Adult; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Fasti | 2002 |
[Studies on thyroid hormone autoantibody in two euthyroid cases with spuriously high value of serum free triiodothyronine].
Topics: Adult; Autoantibodies; Diabetes Mellitus, Type 2; Female; Humans; Immunoglobulin G; Middle Aged; Thy | 1992 |
Thyroid hormone stimulated glucose uptake in human mononuclear blood cells from normal persons and from patients with non-insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Humans; Middle Aged; Oxygen Consumption | 1989 |
Decreased thyroidal response to thyrotropin in type II diabetes mellitus.
Topics: Adult; Animals; Cattle; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Thyroid Gland; | 1988 |
Thyroid hormones in non-insulin dependent diabetes mellitus.
Topics: Adult; Diabetes Mellitus, Type 2; Humans; Male; Middle Aged; Thyrotropin; Thyroxine; Triiodothyronin | 1988 |
Metabolic and thyroidal responses to mild cold are abnormal in obese diabetic women.
Topics: Adult; Cold Temperature; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Hu | 1988 |
Glucose metabolism in noninsulin-dependent diabetic patients with experimental hyperthyroidism.
Topics: Adult; Aged; Blood Glucose; Chemical Phenomena; Chemistry; Diabetes Mellitus, Type 2; Female; Glucos | 1985 |
[Changes in T4-deiodination in decompensated diabetes mellitus. The low-T3 syndrome].
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Male; Syndrome; Thyrotropin; T | 1985 |