triiodothyronine has been researched along with Diabetes, Gestational in 13 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Diabetes, Gestational: Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To estimate the association of free triiodothyronine (FT3) and total triiodothyronine (TT3) in early pregnancy and subsequent gestational diabetes mellitus (GDM) risk and define appropriate TT3 thresholds for GDM screening." | 8.31 | Association of Early Pregnancy Free and Total Triiodothyronine With the Subsequent Risk of Gestational Diabetes Mellitus. ( Li, MQ; Peng, T; Pérez-López, FR; Wu, JN; Xie, F, 2023) |
| "Exposure to triclosan (TCS), an antibacterial agent, during pregnancy is associated with hypothyroxinemia and decreases in placental glucose transporter expression and activity." | 7.85 | Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction. ( Cao, XY; Chen, L; Hua, X; Sun, P; Wang, XL, 2017) |
| "To estimate the association of free triiodothyronine (FT3) and total triiodothyronine (TT3) in early pregnancy and subsequent gestational diabetes mellitus (GDM) risk and define appropriate TT3 thresholds for GDM screening." | 4.31 | Association of Early Pregnancy Free and Total Triiodothyronine With the Subsequent Risk of Gestational Diabetes Mellitus. ( Li, MQ; Peng, T; Pérez-López, FR; Wu, JN; Xie, F, 2023) |
| "During early pregnancy, the gestational diabetes mellitus group displayed lower levels of free thyroxine when compared to the non-gestational diabetes mellitus group." | 4.31 | Free triiodothyronine (FT3)-to-free thyroxine (FT4) ratio identified as a risk factor for gestational diabetes in euthyroid pregnant women: insights from a Chinese population cohort study. ( Sun, J; Yuan, N; Zhang, X; Zhao, X, 2023) |
| "Exposure to triclosan (TCS), an antibacterial agent, during pregnancy is associated with hypothyroxinemia and decreases in placental glucose transporter expression and activity." | 3.85 | Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction. ( Cao, XY; Chen, L; Hua, X; Sun, P; Wang, XL, 2017) |
| "It is frequently preceded by gestational diabetes." | 2.67 | Reduced postprandial energy expenditure in women predisposed to type 2 diabetes. ( Anyaoku, V; Beard, RW; Elkeles, RS; Johnston, DG; Niththyananthan, R; Robinson, S, 1994) |
| "To find out any association between gestational diabetes mellitus (GDM) and thyroid status (TS) throughout pregnancy in Bangladesh." | 1.62 | Association of gestational diabetes mellitus and thyroid status during pregnancy: a cross-sectional study in a tertiary health care center of Bangladesh. ( Ferdous, M; Ferdousi, S; Gomes, RR; Rahman, KMT; Shahid, MM; Zahan, T, 2021) |
| "Patients with type 2 diabetes are tested for thyroid function in view of the associated weight gain, IR, and changes in metabolism." | 1.62 | The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus. ( Kamenov, Z; Yanachkova, V, 2021) |
| "Both gestational diabetes mellitus (GDM) and thyroid dysfunction in pregnancy compromise maternal and fetal health." | 1.33 | Thyroid function abnormalities and antithyroid antibody prevalence in pregnant women at high risk for gestational diabetes mellitus. ( Agarwal, MM; Bishawi, B; Dhatt, GS; Punnose, J; Zayed, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 8 (61.54) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, S | 1 |
| Wu, Y | 1 |
| Pan, W | 1 |
| Li, G | 1 |
| Zhang, D | 1 |
| Li, S | 1 |
| Huang, Q | 1 |
| Liu, ZM | 1 |
| Wang, Y | 1 |
| Lu, S | 1 |
| Xu, X | 1 |
| Zhang, L | 1 |
| Yang, J | 1 |
| Hu, W | 1 |
| Wu, JN | 1 |
| Pérez-López, FR | 1 |
| Peng, T | 1 |
| Xie, F | 1 |
| Li, MQ | 1 |
| Zhao, X | 1 |
| Sun, J | 1 |
| Yuan, N | 1 |
| Zhang, X | 1 |
| Hofstee, P | 1 |
| James-McAlpine, J | 1 |
| McKeating, DR | 1 |
| Vanderlelie, JJ | 1 |
| Cuffe, JSM | 1 |
| Perkins, AV | 1 |
| Gutiérrez-Vega, S | 1 |
| Armella, A | 1 |
| Mennickent, D | 1 |
| Loyola, M | 1 |
| Covarrubias, A | 1 |
| Ortega-Contreras, B | 1 |
| Escudero, C | 1 |
| Gonzalez, M | 1 |
| Alcalá, M | 1 |
| Ramos, MDP | 1 |
| Viana, M | 1 |
| Castro, E | 1 |
| Leiva, A | 1 |
| Guzmán-Gutiérrez, E | 1 |
| Shahid, MM | 1 |
| Rahman, KMT | 1 |
| Gomes, RR | 1 |
| Ferdous, M | 1 |
| Ferdousi, S | 1 |
| Zahan, T | 1 |
| Yanachkova, V | 1 |
| Kamenov, Z | 1 |
| Hua, X | 1 |
| Cao, XY | 1 |
| Wang, XL | 1 |
| Sun, P | 1 |
| Chen, L | 1 |
| Rawal, S | 1 |
| Tsai, MY | 1 |
| Hinkle, SN | 1 |
| Zhu, Y | 1 |
| Bao, W | 1 |
| Lin, Y | 1 |
| Panuganti, P | 1 |
| Albert, PS | 1 |
| Ma, RCW | 1 |
| Zhang, C | 1 |
| Gorar, S | 1 |
| Abanonu, GB | 1 |
| Uysal, A | 1 |
| Erol, O | 1 |
| Unal, A | 1 |
| Uyar, S | 1 |
| Cekin, AH | 1 |
| Agarwal, MM | 1 |
| Dhatt, GS | 1 |
| Punnose, J | 1 |
| Bishawi, B | 1 |
| Zayed, R | 1 |
| Robinson, S | 1 |
| Niththyananthan, R | 1 |
| Anyaoku, V | 1 |
| Elkeles, RS | 1 |
| Beard, RW | 1 |
| Johnston, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The National Standard for Normal Fetal Growth[NCT00912132] | 2,802 participants (Actual) | Observational | 2009-05-19 | Completed | |||
| Maternal TSH Level and TPOAb Status in Early Pregnancy and Their Relationship to the Risk of Gestational Diabetes Mellitus[NCT02555332] | 7,729 participants (Actual) | Observational | 2012-12-31 | Completed | |||
| Energy Balance Following Islet Transplantation[NCT03063229] | 2 participants (Actual) | Interventional | 2016-06-30 | Terminated (stopped due to Unable to recruit participants due to lack of patients eligible at the time) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for triiodothyronine and Diabetes, Gestational
| Article | Year |
|---|---|
High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus.
Topics: Adult; Diabetes, Gestational; Female; Gene Expression Regulation, Enzymologic; Humans; Iodide Peroxi | 2020 |
Reduced postprandial energy expenditure in women predisposed to type 2 diabetes.
Topics: Adult; Blood Glucose; Body Temperature Regulation; Diabetes Mellitus, Type 2; Diabetes, Gestational; | 1994 |
11 other studies available for triiodothyronine and Diabetes, Gestational
| Article | Year |
|---|---|
Free-Triiodothyronine to Free-Thyroxine Ratio Mediated the Effect of Prepregnancy Body Mass Index or Maternal Weight Gain During Early Pregnancy on Gestational Diabetes Mellitus.
Topics: Body Mass Index; Cohort Studies; Diabetes, Gestational; Female; Gestational Weight Gain; Humans; Inf | 2022 |
The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis.
Topics: Body Mass Index; Case-Control Studies; Diabetes, Gestational; Female; Humans; Lipids; Obesity; Pregn | 2022 |
Association of Early Pregnancy Free and Total Triiodothyronine With the Subsequent Risk of Gestational Diabetes Mellitus.
Topics: Cohort Studies; Diabetes, Gestational; Female; Humans; Hypothyroidism; Pregnancy; Thyroid Function T | 2023 |
Free triiodothyronine (FT3)-to-free thyroxine (FT4) ratio identified as a risk factor for gestational diabetes in euthyroid pregnant women: insights from a Chinese population cohort study.
Topics: Blood Glucose; Cohort Studies; Diabetes, Gestational; East Asian People; Female; Humans; Pregnancy; | 2023 |
Low serum selenium in pregnancy is associated with reduced T3 and increased risk of GDM.
Topics: Diabetes, Gestational; Female; Humans; Infant, Newborn; Male; Pregnancy; Selenium; Thyrotropin; Thyr | 2021 |
Association of gestational diabetes mellitus and thyroid status during pregnancy: a cross-sectional study in a tertiary health care center of Bangladesh.
Topics: Adult; Bangladesh; Case-Control Studies; Cross-Sectional Studies; Diabetes, Gestational; Female; Hum | 2021 |
The relationship between thyroid dysfunction during pregnancy and gestational diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Pregnancy; Retrospective Studies; | 2021 |
Exposure of Pregnant Mice to Triclosan Causes Insulin Resistance via Thyroxine Reduction.
Topics: Adipose Tissue; Animals; Anti-Infective Agents, Local; Biomarkers; Blood Glucose; Diabetes, Gestatio | 2017 |
A Longitudinal Study of Thyroid Markers Across Pregnancy and the Risk of Gestational Diabetes.
Topics: Adult; Biomarkers; Case-Control Studies; Diabetes, Gestational; Female; Humans; Logistic Models; Lon | 2018 |
Comparison of thyroid function tests and blood count in pregnant women with versus without gestational diabetes mellitus.
Topics: Adult; Age Factors; Blood Cell Count; Diabetes, Gestational; Female; Humans; Mean Platelet Volume; P | 2017 |
Thyroid function abnormalities and antithyroid antibody prevalence in pregnant women at high risk for gestational diabetes mellitus.
Topics: Adult; Autoantibodies; Body Mass Index; Diabetes, Gestational; Ethnicity; Female; Gestational Age; G | 2006 |