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triiodothyronine and Developmental Psychomotor Disorders

triiodothyronine has been researched along with Developmental Psychomotor Disorders in 9 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"To identify the molecular defect by which psychomotor retardation is caused in two brothers with congenital hypothyroidism who received adequate treatment with l-thyroxine."3.72A new heterozygous mutation (L338N) in the human Gsalpha (GNAS1) gene as a cause for congenital hypothyroidism in Albright's hereditary osteodystrophy. ( Ahrens, W; Hiort, O; Pohlenz, J, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's5 (55.56)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vlaeminck-Guillem, V1
Espiard, S1
Flamant, F1
Wémeau, JL2
Kersseboom, S1
Visser, TJ4
Pohlenz, J1
Ahrens, W1
Hiort, O1
Friesema, EC2
Jansen, J2
Heuer, H1
Trajkovic, M1
Bauer, K1
Kester, MH1
Milici, C1
Reeser, M1
Grüters, A1
Barrett, TG1
Mancilla, EE1
Svensson, J1
Busi da Silva Canalli, MH1
Lundgren, J1
McEntagart, ME1
Hopper, N1
Arts, WF1
Spiliotis, BE1
Samson, JA1
Mirin, SM1
Griffin, M1
Borrelli, D1
Schildkraut, JJ1
Lehr, HJ1
Werner, H1
Rudorff, KH1
Herrmann, J1

Reviews

3 reviews available for triiodothyronine and Developmental Psychomotor Disorders

ArticleYear
TRα receptor mutations extend the spectrum of syndromes of reduced sensitivity to thyroid hormone.
    Presse medicale (Paris, France : 1983), 2015, Volume: 44, Issue:11

    Topics: Abnormalities, Multiple; Adolescent; Adult; Age of Onset; Bradycardia; Child; Codon, Nonsense; Dwarf

2015
Mechanisms of disease: psychomotor retardation and high T3 levels caused by mutations in monocarboxylate transporter 8.
    Nature clinical practice. Endocrinology & metabolism, 2006, Volume: 2, Issue:9

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Genetic Testing; Humans; Kidney; Liver; Male; Mice;

2006
Thyroid hormone transporters.
    Hormone research, 2007, Volume: 68 Suppl 5

    Topics: Brain; Carrier Proteins; Cell Membrane; Chromosomes, Human, X; Drug Resistance; Humans; Male; Monoca

2007

Other Studies

6 other studies available for triiodothyronine and Developmental Psychomotor Disorders

ArticleYear
MCT8: from gene to disease and therapeutic approach.
    Annales d'endocrinologie, 2011, Volume: 72, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Brain; Humans; Kidney; Male; Mi

2011
A new heterozygous mutation (L338N) in the human Gsalpha (GNAS1) gene as a cause for congenital hypothyroidism in Albright's hereditary osteodystrophy.
    European journal of endocrinology, 2003, Volume: 148, Issue:4

    Topics: Calcium; Child; Erythrocyte Membrane; Fibrous Dysplasia, Polyostotic; Genotype; GTP-Binding Protein

2003
Functional analysis of monocarboxylate transporter 8 mutations identified in patients with X-linked psychomotor retardation and elevated serum triiodothyronine.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:6

    Topics: Cell Line, Tumor; Codon, Nonsense; Gene Deletion; Genetic Diseases, X-Linked; Humans; Intellectual D

2007
Pediatric topic: expanding the spectrum of Noonan syndrome.
    Hormone research, 2007, Volume: 68 Suppl 5

    Topics: Adult; Humans; Infant; Monocarboxylic Acid Transporters; Mutation; Noonan Syndrome; Protein Tyrosine

2007
Urinary MHPG and clinical symptoms in patients with unipolar depression.
    Psychiatry research, 1994, Volume: 51, Issue:2

    Topics: Adult; Body Weight; Cognition Disorders; Depressive Disorder; Dexamethasone; Female; Humans; Hydroco

1994
[T3-thyrotoxicosis in a 3-year-old girl (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Jun-28, Volume: 99, Issue:26

    Topics: Age Determination by Skeleton; Bone Development; Child, Preschool; Diarrhea; Exophthalmos; Female; G

1974