Page last updated: 2024-11-08

triiodothyronine and Delayed Effects, Prenatal Exposure

triiodothyronine has been researched along with Delayed Effects, Prenatal Exposure in 86 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Triclosan was not associated with thyroid hormones during pregnancy."3.88Associations of early life urinary triclosan concentrations with maternal, neonatal, and child thyroid hormone levels. ( Braun, JM; Chen, A; Hauser, R; Hoofnagle, A; Jackson-Browne, M; Karagas, MR; Lanphear, BP; Papandonatos, GD; Romano, ME; Thomas Zoeller, R; Yolton, K, 2018)
" All women had a blood sample drawn in early pregnancy (median week 9), and the stored sample was used for measurement of free thyroxine and thyrotropin."3.88Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study. ( Andersen, S; Andersen, SL; Olsen, J; Vestergaard, P, 2018)
"Excessive iodine intake during pregnancy was associated with an increased rate of hyperthyrotropinaemia in neonates and their mothers, especially in male neonates."3.81Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water. ( Chen, W; Chu, Z; Dong, F; Sang, Z; Shen, J; Tan, L; Wei, W; Yao, Z; Zhang, G; Zhang, S; Zhang, W; Zhao, N, 2015)
"Three groups of male and female rats were studied at the postnatal day 25: the offspring of control dams, the offspring of 20% calorie-restricted dams during pregnancy (CR) and CR rats supplemented with physiological doses of leptin throughout lactation (CR-Leptin)."3.81Leptin intake in suckling rats restores altered T3 levels and markers of adipose tissue sympathetic drive and function caused by gestational calorie restriction. ( Konieczna, J; Palou, A; Palou, M; Picó, C; Sánchez, J, 2015)
"Excessive iodine exposure during the fetal and neonatal periods can lead to neonatal hypothyroidism."3.80Effect of iodine loading on the thyroid hormone level of newborns living in Kayseri province. ( Bastug, O; Daar, G; Gunes, T; Halis, H; Korkmaz, L; Korkut, S; Kurtoglu, S; Memur, S; Ozturk, MA, 2014)
" We have previously reported the presence of SBH in a rodent model of low level hypothyroidism induced by maternal exposure to the goitrogen, propylthiouracil (PTU)."3.80Subcortical band heterotopia in rat offspring following maternal hypothyroxinaemia: structural and functional characteristics. ( Gilbert, ME; Goodman, JH; McCloskey, DP; Ramos, RL, 2014)
"To investigate the effects of maternal selenium (Se) supplementation and nutritional intake during gestation on hormone changes, percentage body weight (BW) change, and organ mass in neonatal lambs, ewes were allocated to differing Se levels (adequate Se (ASe, 11."3.78Neonatal hormone changes and growth in lambs born to dams receiving differing nutritional intakes and selenium supplementation during gestation. ( Camacho, LE; Caton, JS; Hammer, CJ; Meyer, AM; Neville, TL; Redmer, DA; Reynolds, LP; Vonnahme, KA, 2012)
"Our results indicate a risk of postnatal hypothyroidism among lambs from pregnant and lactating ewes having a high iodine intake."3.78The impact of high iodine intake on thyroid function in ewes and lambs. ( Baňoch, T; Dušová, H; Konečný, R; Kroupová, V; Peksa, Z; Svoboda, M; Trávníček, J, 2012)
"Hypothyroidism in the rat induced by perinatal exposure to propylthiouracil (PTU) is a useful animal model to study molecular changes underlying neurobehavioral defects associated with this condition."3.73Effects of hypothyroidism induced by perinatal exposure to PTU on rat behavior and synaptic gene expression. ( Kobayashi, K; Kushida, M; Mino, T; Sasaki, M; Seki, T; Tsuji, R; Yabushita, S; Yoshioka, T, 2005)
" Conversely, neonatal rat hyperthyroidism, induced by daily injections of 3,5,3'-triiodothyronine (T3), accelerated the extension of microglial processes and increased the density of cortical microglial cell bodies above physiological levels during the first postnatal week of life."3.71Regulation of microglial development: a novel role for thyroid hormone. ( Colin, C; Gervais, A; Izembart, M; Lima, FR; Mallat, M; Neto, VM, 2001)
"Following the diagnosis of fetal goitre at 22 and 24 weeks' gestation in two hyperthyroid pregnant women who underwent treatment with 400-500 mg of propylthiouracil in the first weeks of pregnancy, a total of seven fetal blood samplings were performed to evaluate thyroid function before and after the initiation of two different treatment regimens."3.69Prenatal treatment of fetal hypothyroidism: is there more than one option? ( Acaia, B; Beck-Peccoz, P; Cortelazzi, D; Nicolini, U; Venegoni, E, 1996)
"Pregnant rats were injected with triiodothyronine (T3) on the 19th and 20th days of pregnancy."3.66The effect of 3,5,3'-triiodothyronine on phosphoenolpyruvate carboxykinase, fatty acid synthetase and malic enzyme activity of liver and brown fat of fetal and neonatal rats. ( Hahn, P; Hassanali, S, 1982)
" The dose-response relationship between PAH metabolites and thyroid hormones was analyzed using the generalized linear model and restricted cubic spline model."1.91Associations between prenatal exposure to polycyclic aromatic hydrocarbons and thyroid hormones in umbilical cord blood. ( Fu, M; Ma, Y; Nie, J; Tang, D; Wang, H; Wang, Y; Yao, X, 2023)
"Chlordecone is an endocrine-disrupting chemical with well recognized estrogenic and progestagenic properties."1.62 ( Ayhan, G; Cordier, S; Costet, N; Giton, F; Kadhel, P; Michineau, L; Monfort, C; Multigner, L; Oliva, A; Rouget, F; Thomé, JP, 2021)
" Urinary bis(1,3-dichloro-2-propyl)-phosphate concentrations were generally associated with decreased triiodothyronine and thyroxine levels and increased thyroid-stimulating hormone levels in maternal and newborn thyroid hormones in quartile dose-response analyses and multiple informant models."1.62Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones. ( Braun, JM; Calafat, AM; Cecil, KM; Chen, A; Dietrich, KN; Hoofnagle, A; Lanphear, BP; Ospina, M; Percy, Z; Vuong, AM; Xie, C; Xu, Y; Yolton, K, 2021)
"Subclinical hypothyroidism is caused by thyroid hormone deficit and can lead to impairments in mood and cognition."1.46Prenatal exposure to brain-specific anion transporter-1-specific monoclonal antibodies impairs cognitive function in post-natal life. ( Chekhonin, VP; Gurina, OI; Melnikov, PA; Morozova, AY; Zorkina, YA; Zubkov, EA, 2017)
" Insufficient thyroid hormone levels are one mechanism that hampers development of the alcohol-exposed brain, and we hypothesized that altered dosage of the imprinted thyroid hormone-inactivating gene deiodinase-III (Dio3) is responsible."1.37Strain-specific vulnerability to alcohol exposure in utero via hippocampal parent-of-origin expression of deiodinase-III. ( Herzing, LB; Redei, EE; Shukla, PK; Sittig, LJ, 2011)
" Rats were perinatally dosed with a commercial PBDE mixture, DE-71."1.37Altered cardiovascular reactivity and osmoregulation during hyperosmotic stress in adult rats developmentally exposed to polybrominated diphenyl ethers (PBDEs). ( Coburn, CG; Currás-Collazo, MC; Gaertner, M; Gillard, ER; Kodavanti, PR; Leon-Olea, M; Nichol, R; Shah, A; Shahidzadeh, A; Watson-Siriboe, A; Whitley, R, 2011)
"Hypothyroidism was induced in pregnant and lactating rats by feeding 0."1.36Gestational and neonatal-onset hypothyroidism alters androgen receptor status in rat prostate glands at adulthood. ( Aruldhas, MM; Jaganathan, A; John Sashi, AM; Kannan, A; Nagappan, AS; Ramalingam, N; Seshadri, VN; Stanley, JA; Vasavan, J, 2010)
"Alcohol treatment during pregnancy decreased highly significantly the content of both hormones in peritoneal cells of the 4 month old adult animals while it was ineffective by breast feeding after birth."1.33Alcohol consumption during gestation reduces the histamine and triiodothyronine content of rat immune cells. ( Csaba, G; Kovács, P; Pállinger, E, 2005)
"Nitrofen treatment led to decreased plasma T3 and T4 levels without TSH changes."1.30Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen. ( Alfonso, LF; Alvarez, FJ; Arnaiz, A; Diez-Pardo, JA; Morreale de Escobar, G; Qi, B; Tovar, JA; Valls-i-Soler, A, 1997)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-19908 (9.30)18.7374
1990's13 (15.12)18.2507
2000's28 (32.56)29.6817
2010's32 (37.21)24.3611
2020's5 (5.81)2.80

Authors

AuthorsStudies
Ayhan, G1
Rouget, F1
Giton, F1
Costet, N1
Michineau, L1
Monfort, C1
Thomé, JP1
Kadhel, P1
Cordier, S1
Oliva, A1
Multigner, L1
Yao, X1
Wang, Y2
Ma, Y1
Fu, M1
Wang, H1
Tang, D1
Nie, J1
Abdel-Wahab, A1
Hassanin, KMA1
Ibrahim, SS1
El-Kossi, DMMH1
Abdel-Razik, AH1
Percy, Z1
Vuong, AM1
Xu, Y1
Xie, C1
Ospina, M1
Calafat, AM1
Hoofnagle, A2
Lanphear, BP2
Braun, JM2
Cecil, KM1
Dietrich, KN1
Yolton, K2
Chen, A2
Pedaran, M1
Oelkrug, R1
Sun, Q1
Resch, J1
Schomburg, L1
Mittag, J2
Zubkov, EA1
Zorkina, YA1
Gurina, OI1
Melnikov, PA1
Morozova, AY1
Chekhonin, VP1
Huang, HB1
Chuang, CJ1
Su, PH2
Sun, CW1
Wang, CJ1
Wu, MT1
Wang, SL2
Papandonatos, GD1
Jackson-Browne, M1
Hauser, R1
Romano, ME1
Karagas, MR1
Thomas Zoeller, R1
Andersen, SL1
Andersen, S1
Vestergaard, P1
Olsen, J1
Chattergoon, NN1
Czerska, M1
Zieliński, M1
Kamińska, J1
Ligocka, D1
Sawicka-Gutaj, N1
Gutaj, P1
Sowiński, J1
Wender-Ożegowska, E1
Czarnywojtek, A1
Brązert, J1
Ruchała, M1
Kurtoglu, S1
Bastug, O1
Daar, G1
Halis, H1
Korkmaz, L1
Memur, S1
Korkut, S1
Gunes, T1
Ozturk, MA1
Inoue, A1
Arima, A1
Kato, H1
Yamashita, N1
Nishida, Y1
Ooshima, Y1
Ebihara, S1
Gilbert, ME2
Ramos, RL1
McCloskey, DP1
Goodman, JH1
Chen, W1
Sang, Z1
Tan, L1
Zhang, S1
Dong, F1
Chu, Z1
Wei, W1
Zhao, N1
Zhang, G1
Yao, Z1
Shen, J1
Zhang, W1
Konieczna, J1
Palou, M1
Sánchez, J1
Picó, C1
Palou, A1
Chen, HY1
Chen, SJ1
Chen, JY1
Liou, SH1
Sanchez-Huerta, K1
Wood, C1
Yang, L1
Li, J1
Lai, J1
Luan, H1
Cai, Z1
Zhao, Y1
Wu, Y1
Zhang, Q1
Zhang, D1
Ye, K1
Liu, K1
Sheng, J1
Liu, Y1
Hu, C1
Ruan, L1
Li, L1
Tao, F1
Özgür, E1
Gürbüz Özgür, B1
Aksu, H1
Cesur, G1
Chauvet, P1
Terral, D1
Colombier, M1
Mulliez, A1
Suarez, C1
Brunhes, A1
Gallot, D1
Kobayashi, K3
Miyagawa, M2
Wang, RS2
Suda, M2
Sekiguchi, S2
Honma, T2
Vujovic, M1
Nordström, K1
Gauthier, K1
Flamant, F1
Visser, TJ1
Vennström, B1
Lopez-Espinosa, MJ1
Vizcaino, E1
Murcia, M1
Llop, S1
Espada, M1
Seco, V1
Marco, A1
Rebagliato, M1
Grimalt, JO1
Ballester, F1
Csaba, G2
Tekes, K1
Pállinger, E2
Chang, SC1
Ehresman, DJ1
Bjork, JA1
Wallace, KB1
Parker, GA1
Stump, DG1
Butenhoff, JL1
Saegusa, Y1
Fujimoto, H1
Woo, GH1
Inoue, K1
Takahashi, M1
Mitsumori, K2
Hirose, M1
Nishikawa, A1
Shibutani, M2
Dallaire, R1
Muckle, G1
Dewailly, E1
Jacobson, SW1
Jacobson, JL1
Sandanger, TM1
Sandau, CD1
Ayotte, P1
Anselmo, CW1
Pereira, PB1
Catanho, MT1
Medeiros, MC1
Haviland, JA1
Butz, DE1
Porter, WP1
Shukla, PK2
Sittig, LJ2
Andrus, BM1
Schaffer, DJ1
Batra, KK1
Redei, EE4
Aruldhas, MM1
Ramalingam, N1
Jaganathan, A1
John Sashi, AM1
Stanley, JA1
Nagappan, AS1
Vasavan, J1
Kannan, A1
Seshadri, VN1
Rooke, JA1
Houdijk, JG1
McIlvaney, K1
Ashworth, CJ1
Dwyer, CM1
Veiga-Lopez, A1
Steckler, TL1
Abbott, DH1
Welch, KB1
MohanKumar, PS1
Phillips, DJ1
Refsal, K1
Padmanabhan, V1
Herzing, LB1
Wang, F1
Liu, W1
Jin, Y1
Dai, J1
Zhao, H1
Xie, Q1
Liu, X1
Yu, W1
Ma, J1
Julvez, J1
Debes, F1
Weihe, P1
Choi, AL1
Grandjean, P1
Shah, A1
Coburn, CG1
Watson-Siriboe, A1
Whitley, R1
Shahidzadeh, A1
Gillard, ER1
Nichol, R1
Leon-Olea, M1
Gaertner, M1
Kodavanti, PR1
Currás-Collazo, MC1
Brucker-Davis, F1
Ferrari, P1
Boda-Buccino, M1
Wagner-Mahler, K1
Pacini, P1
Gal, J1
Azuar, P1
Fenichel, P1
Camacho, LE1
Meyer, AM1
Neville, TL1
Hammer, CJ1
Redmer, DA1
Reynolds, LP1
Caton, JS1
Vonnahme, KA1
Ohishi, T1
Wang, L1
Akane, H1
Shiraki, A1
Goto, K1
Ikarashi, Y1
Suzuki, K1
Carbone, DL1
Zuloaga, DG1
Lacagnina, AF1
McGivern, RF1
Handa, RJ1
Dušová, H1
Trávníček, J1
Svoboda, M1
Baňoch, T1
Kroupová, V1
Peksa, Z1
Konečný, R1
Kuriyama, S1
Fidalgo-Neto, A1
Mathar, W1
Palavinskas, R1
Friedrich, K1
Chahoud, I1
Wilcoxon, JS1
Slone-Wilcoxon, J1
Chen, WJ1
Kelly, RB1
Alvarez, M1
Perez-Castillo, A2
Santos, A2
Tsuji, R1
Yoshioka, T1
Kushida, M1
Yabushita, S1
Sasaki, M1
Mino, T1
Seki, T1
Kovács, P1
Gabrichidze, GO1
Lazrishvili, NI1
Metreveli, DS1
Bekaia, GL1
Mitagvariia, NP1
Guo, HL1
Hou, XH1
Yang, XF1
Xu, J2
Bono, E1
Compagno, V1
Proia, P1
Raimondi, L1
Schiera, G1
Favaloro, V1
Campo, V1
Donatelli, M1
Di Liegro, I1
Ishitobi, H1
Mori, K1
Yoshida, K1
Watanabe, C1
Rivas, M1
Naranjo, JR1
Guo, H1
Feng, J1
Yang, X1
Tseng, LH1
Li, MH1
Tsai, SS1
Lee, CW1
Pan, MH1
Yao, WJ1
Hsu, PC1
Kato, N1
Sundmark, VC1
Van Middlesworth, L1
Havlicek, V1
Friesen, HG1
l'Allemand, D1
Grüters, A1
Heidemann, P1
Schürnbrand, P1
Hahn, P1
Hassanali, S1
Goldey, ES1
Kehn, LS1
Lau, C1
Rehnberg, GL1
Crofton, KM2
Seo, BW2
Meserve, LA1
Anguita, RM1
Sigulem, DM1
Sawaya, AL1
Aldrich, SL2
Berger, LL2
Reiling, BA1
Kesler, DJ2
Nash, TG2
McCusker, RH1
Nicolini, U1
Venegoni, E1
Acaia, B1
Cortelazzi, D1
Beck-Peccoz, P1
Chaudhury, S2
Bajpai, M1
Bhattacharya, S1
Djouadi, F1
Riveau, B1
Merlet-Benichou, C1
Bastin, J1
Rosiak, KL1
Chu, I1
Francis, BM1
Tovar, JA1
Qi, B1
Diez-Pardo, JA1
Alfonso, LF1
Arnaiz, A1
Alvarez, FJ1
Valls-i-Soler, A1
Morreale de Escobar, G1
Finsten, A1
Donald, A1
Bate, LA1
Lakshmy, R1
Khurana, ML1
Das, BC1
Shah, P1
Ammini, AC1
Ervin, MG1
Padbury, JF1
Polk, DH1
Ikegami, M2
Berry, LM1
Jobe, AH2
Lima, FR1
Gervais, A1
Colin, C1
Izembart, M1
Neto, VM1
Mallat, M1
Martinez, B1
del Hoyo, P1
Martin, MA1
Arenas, J1
Banerjee, B1
Zhou, T1
Taylor, MM1
DeVito, MJ1
Messer, PM1
Hauffa, BP1
Olbricht, T1
Benker, G1
Kotulla, P1
Reinwein, D1
Thakare, UR1
Shah, DH1
Vijayan, U1
Moya, F1
Mena, P1
Heusser, F1
Foradori, A1
Paiva, E1
Yazigi, R1
Michaud, P1
Gross, I1
Pettenazzo, A1
Seidner, SR1
Berry, DD1
Ruffini, L1
Specchio, LM1
Cavallo, L1
La Neve, A1
Licci, D1
Sisto, L1
Mautone, A1
Porterfield, SP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women[NCT04492657]600 participants (Anticipated)Observational2020-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for triiodothyronine and Delayed Effects, Prenatal Exposure

ArticleYear
Thyroid hormone signaling and consequences for cardiac development.
    The Journal of endocrinology, 2019, 07-01, Volume: 242, Issue:1

    Topics: Animals; Cardiovascular Diseases; Cell Proliferation; Female; Fetal Development; Fetal Heart; Heart;

2019
Effects of polybrominated diphenyl ethers on thyroid hormone, neurodevelopment and fertility in rodents and humans.
    International journal of occupational medicine and environmental health, 2013, Volume: 26, Issue:4

    Topics: Animals; Endocrine Disruptors; Female; Fertility; Flame Retardants; Genitalia, Male; Halogenated Dip

2013
Influence of cigarette smoking on thyroid gland--an update.
    Endokrynologia Polska, 2014, Volume: 65, Issue:1

    Topics: Female; Graves Disease; Hashimoto Disease; Humans; Hyperthyroidism; Hypothyroidism; Pregnancy; Pregn

2014
Thyroid hormones, learning and memory.
    Genes, brain, and behavior, 2007, Volume: 6 Suppl 1

    Topics: Animals; Cognition; Disease Models, Animal; Female; Humans; Learning; Memory; Mice; Mice, Transgenic

2007

Trials

1 trial available for triiodothyronine and Delayed Effects, Prenatal Exposure

ArticleYear
Differential effects of maternal undernutrition between days 1 and 90 of pregnancy on ewe and lamb performance and lamb parasitism in hill or lowland breeds.
    Journal of animal science, 2010, Volume: 88, Issue:12

    Topics: Animal Nutritional Physiological Phenomena; Animals; Breeding; Female; Genetic Predisposition to Dis

2010

Other Studies

81 other studies available for triiodothyronine and Delayed Effects, Prenatal Exposure

ArticleYear
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adiponectin; Child; Chlordecone; Dehydroepiandrosterone; Dihydrotestosterone; Environmental Exposure

2021
Associations between prenatal exposure to polycyclic aromatic hydrocarbons and thyroid hormones in umbilical cord blood.
    Environmental science and pollution research international, 2023, Volume: 30, Issue:31

    Topics: Female; Fetal Blood; Humans; Infant, Newborn; Polycyclic Aromatic Hydrocarbons; Pregnancy; Prenatal

2023
Developmental Programming: Physiological Impacts of Prenatal Melatonin Administration on Reproductive Capacity and Serum Triiodothyronine of Adult Female Offspring Rat Born to Moms Exposed to Bisphenol A During Pregnancy.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:7

    Topics: Animals; Benzhydryl Compounds; Female; Melatonin; Phenols; Pregnancy; Prenatal Exposure Delayed Effe

2021
Maternal Urinary Organophosphate Esters and Alterations in Maternal and Neonatal Thyroid Hormones.
    American journal of epidemiology, 2021, 09-01, Volume: 190, Issue:9

    Topics: Adolescent; Adult; Environmental Exposure; Female; Fetal Blood; Flame Retardants; Humans; Infant, Ne

2021
Maternal Thyroid Hormone Programs Cardiovascular Functions in the Offspring.
    Thyroid : official journal of the American Thyroid Association, 2021, Volume: 31, Issue:9

    Topics: Animals; Arterial Pressure; Cardiovascular System; DNA Methylation; Female; Gene Expression Regulati

2021
Prenatal exposure to brain-specific anion transporter-1-specific monoclonal antibodies impairs cognitive function in post-natal life.
    Neuropeptides, 2017, Volume: 65

    Topics: Animals; Antibodies, Monoclonal; Blood-Brain Barrier; Brain; Cognition; Female; Hypothyroidism; Male

2017
Prenatal and Childhood Exposure to Phthalate Diesters and Thyroid Function in a 9-Year Follow-up Birth Cohort Study: Taiwan Maternal and Infant Cohort Study.
    Epidemiology (Cambridge, Mass.), 2017, Volume: 28 Suppl 1

    Topics: Adult; Child; Child, Preschool; Cohort Studies; Diethylhexyl Phthalate; Environmental Exposure; Fema

2017
Associations of early life urinary triclosan concentrations with maternal, neonatal, and child thyroid hormone levels.
    Hormones and behavior, 2018, Volume: 101

    Topics: Adolescent; Adult; Child, Preschool; Cohort Studies; Female; Humans; Infant; Infant, Newborn; Male;

2018
Maternal Thyroid Function in Early Pregnancy and Child Neurodevelopmental Disorders: A Danish Nationwide Case-Cohort Study.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:4

    Topics: Adult; Child; Child, Preschool; Denmark; Female; Fetal Development; Humans; Infant; Male; Neurodevel

2018
Effect of iodine loading on the thyroid hormone level of newborns living in Kayseri province.
    American journal of perinatology, 2014, Volume: 31, Issue:12

    Topics: Anti-Infective Agents, Local; Female; Humans; Hypothyroidism; Infant, Newborn; Iodine; Male; Milk, H

2014
Effects of maternal exposure to thiamazole on behavioral development in infant cynomolgus monkeys.
    Congenital anomalies, 2013, Volume: 53, Issue:4

    Topics: Animals; Animals, Newborn; Antithyroid Agents; Behavior, Animal; Female; Macaca fascicularis; Matern

2013
Subcortical band heterotopia in rat offspring following maternal hypothyroxinaemia: structural and functional characteristics.
    Journal of neuroendocrinology, 2014, Volume: 26, Issue:8

    Topics: Animals; Brain; Classical Lissencephalies and Subcortical Band Heterotopias; Dose-Response Relations

2014
Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water.
    Clinical endocrinology, 2015, Volume: 83, Issue:3

    Topics: Adult; China; Cross-Sectional Studies; Drinking Water; Female; Fetal Blood; Geography; Humans; Infan

2015
Leptin intake in suckling rats restores altered T3 levels and markers of adipose tissue sympathetic drive and function caused by gestational calorie restriction.
    International journal of obesity (2005), 2015, Volume: 39, Issue:6

    Topics: Adipose Tissue, White; Administration, Oral; Animals; Animals, Suckling; Blotting, Western; Caloric

2015
Thyroid and growth hormone concentrations in 8-year-old children exposed in utero to dioxins and polychlorinated biphenyls.
    The Journal of toxicological sciences, 2015, Volume: 40, Issue:3

    Topics: Child; Dioxins; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Humans; Insulin-

2015
Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats.
    Endocrinology, 2016, Volume: 157, Issue:2

    Topics: Animals; Antithyroid Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Conditioning, Psyc

2016
Placental Transfer of Perfluoroalkyl Substances and Associations with Thyroid Hormones: Beijing Prenatal Exposure Study.
    Scientific reports, 2016, Feb-22, Volume: 6

    Topics: Adult; Beijing; Caprylates; Decanoic Acids; Environmental Pollutants; Female; Fetal Blood; Fetus; Fl

2016
Physiological and behavioral responses in offspring mice following maternal exposure to sulfamonomethoxine during pregnancy.
    Neuroscience letters, 2016, 06-15, Volume: 624

    Topics: Animals; Anti-Infective Agents; Anxiety; Behavior, Animal; Blood Glucose; Body Weight; Brain-Derived

2016
The Effect of Congenital and Postnatal Hypothyroidism on Depression-Like Behaviors in Juvenile Rats.
    Journal of clinical research in pediatric endocrinology, 2016, 12-01, Volume: 8, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Congenital Hypothyroidism; Depression;

2016
[Iodinated contrast in pregnant women and neonatal thyroid function].
    Gynecologie, obstetrique & fertilite, 2016, Volume: 44, Issue:12

    Topics: Congenital Hypothyroidism; Contrast Media; Female; Gestational Age; Humans; Infant, Newborn; Iodine;

2016
Effects of in utero exposure to 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) on somatic growth and endocrine status in rat offspring.
    Congenital anomalies, 2008, Volume: 48, Issue:4

    Topics: Animals; Animals, Newborn; Female; Growth Hormone; Insulin-Like Growth Factor I; Male; Organ Size; P

2008
Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism.
    Endocrinology, 2009, Volume: 150, Issue:6

    Topics: Animals; Down-Regulation; Fasting; Female; Glucose; Glycogen; Liver; Male; Mice; Mice, Inbred C57BL;

2009
Association between thyroid hormone levels and 4,4'-DDE concentrations in pregnant women (Valencia, Spain).
    Environmental research, 2009, Volume: 109, Issue:4

    Topics: Adolescent; Adult; Biomarkers; Cohort Studies; Dichlorodiphenyl Dichloroethylene; Female; Fetal Deve

2009
Effects of in utero exposure to 2,2',4,4',5,5'-hexachlorobiphenyl on postnatal development and thyroid function in rat offspring.
    Industrial health, 2009, Volume: 47, Issue:2

    Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Environmental Monitoring; Female; Growth and

2009
Influence of perinatal stress on the hormone content in immune cells of adult rats: dominance of ACTH.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2009, Volume: 41, Issue:8

    Topics: Adrenocorticotropic Hormone; Animals; Female; Histamine; Hormones; Leukocytes; Male; Mast Cells; Mat

2009
Gestational and lactational exposure to potassium perfluorooctanesulfonate (K+PFOS) in rats: toxicokinetics, thyroid hormone status, and related gene expression.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 27, Issue:3-4

    Topics: Alkanesulfonic Acids; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Environmental Pol

2009
Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation.
    Reproductive toxicology (Elmsford, N.Y.), 2009, Volume: 28, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Female; Fetus; Flame Retardants; Hydrocarbons, Brominated

2009
Thyroid hormone levels of pregnant inuit women and their infants exposed to environmental contaminants.
    Environmental health perspectives, 2009, Volume: 117, Issue:6

    Topics: Adult; Environmental Exposure; Environmental Pollutants; Female; Hexachlorobenzene; Humans; Infant;

2009
Effects of the electromagnetic field, 60 Hz, 3 microT, on the hormonal and metabolic regulation of undernourished pregnant rats.
    Brazilian journal of biology = Revista brasleira de biologia, 2009, Volume: 69, Issue:2

    Topics: Animals; Electromagnetic Fields; Female; Hydrocortisone; Insulin; Pregnancy; Prenatal Exposure Delay

2009
Long-term sex selective hormonal and behavior alterations in mice exposed to low doses of chlorpyrifos in utero.
    Reproductive toxicology (Elmsford, N.Y.), 2010, Volume: 29, Issue:1

    Topics: Animals; Behavior, Animal; Chlorpyrifos; Female; Gestational Age; Insecticides; Male; Mice; Pregnanc

2010
Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels.
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:6

    Topics: Amygdala; Animals; Anxiety; Corticosterone; Corticotropin-Releasing Hormone; Depressive Disorder; Di

2010
Gestational and neonatal-onset hypothyroidism alters androgen receptor status in rat prostate glands at adulthood.
    The Prostate, 2010, May-15, Volume: 70, Issue:7

    Topics: Analysis of Variance; Animals; Animals, Newborn; Blotting, Western; Estradiol; Female; Hypothyroidis

2010
Developmental programming: impact of excess prenatal testosterone on intrauterine fetal endocrine milieu and growth in sheep.
    Biology of reproduction, 2011, Volume: 84, Issue:1

    Topics: Animals; Blood Glucose; Estrogens; Female; Gene Expression Regulation; Insulin; Insulin-Like Growth

2011
Strain-specific vulnerability to alcohol exposure in utero via hippocampal parent-of-origin expression of deiodinase-III.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, Volume: 25, Issue:7

    Topics: Animals; Blotting, Western; Central Nervous System Depressants; Crosses, Genetic; Ethanol; Female; F

2011
Interaction of PFOS and BDE-47 co-exposure on thyroid hormone levels and TH-related gene and protein expression in developing rat brains.
    Toxicological sciences : an official journal of the Society of Toxicology, 2011, Volume: 121, Issue:2

    Topics: Alkanesulfonic Acids; Animals; Animals, Newborn; Brain-Derived Neurotrophic Factor; Drug Interaction

2011
Thyroid dysfunction as a mediator of organochlorine neurotoxicity in preschool children.
    Environmental health perspectives, 2011, Volume: 119, Issue:10

    Topics: Child, Preschool; Female; Humans; Hydrocarbons, Chlorinated; Hyperthyroidism; Hypothyroidism; Infant

2011
Altered cardiovascular reactivity and osmoregulation during hyperosmotic stress in adult rats developmentally exposed to polybrominated diphenyl ethers (PBDEs).
    Toxicology and applied pharmacology, 2011, Oct-15, Volume: 256, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Blood Pressure; Dose-Response Relationship, Drug; Female; Ha

2011
Cord blood thyroid tests in boys born with and without cryptorchidism: correlations with birth parameters and in utero xenobiotics exposure.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:10

    Topics: Case-Control Studies; Cryptorchidism; Dichlorodiphenyl Dichloroethylene; Endocrine Disruptors; Femal

2011
Neonatal hormone changes and growth in lambs born to dams receiving differing nutritional intakes and selenium supplementation during gestation.
    Reproduction (Cambridge, England), 2012, Volume: 144, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Birth Weight; Body Weight; Di

2012
Reversible aberration of neurogenesis affecting late-stage differentiation in the hippocampal dentate gyrus of rat offspring after maternal exposure to manganese chloride.
    Reproductive toxicology (Elmsford, N.Y.), 2012, Volume: 34, Issue:3

    Topics: Animals; Animals, Newborn; Apoptosis; Cell Proliferation; Cerebellum; Chlorides; Dentate Gyrus; Doub

2012
Exposure to dexamethasone during late gestation causes female-specific decreases in core body temperature and prepro-thyrotropin-releasing hormone expression in the paraventricular nucleus of the hypothalamus in rats.
    Physiology & behavior, 2012, Dec-25, Volume: 108

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents; Body Tempera

2012
The impact of high iodine intake on thyroid function in ewes and lambs.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:5

    Topics: Animals; Animals, Newborn; Female; Hypothyroidism; Iodine; Lactation; Pregnancy; Prenatal Exposure D

2012
Effect of low dose mono-ortho 2,3',4,4',5 pentachlorobiphenyl on thyroid hormone status and EROD activity in rat offspring: consequences for risk assessment.
    Toxicology, 2003, Apr-15, Volume: 186, Issue:1-2

    Topics: Adipose Tissue; Animals; Animals, Newborn; Cytochrome P-450 CYP1A1; Female; Liver; Male; Microsomes,

2003
Prenatal programming of adult thyroid function by alcohol and thyroid hormones.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:2

    Topics: Adaptation, Physiological; Age Factors; Analysis of Variance; Animals; Corticosterone; Ethanol; Fema

2004
Maternal-fetal glucocorticoid milieu programs hypothalamic-pituitary-thyroid function of adult offspring.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Age Factors; Animals; Anti-Inflammatory Agents; Corticos

2004
Effect of prenatal or perinatal nicotine exposure on neonatal thyroid status and offspring growth in rats.
    Life sciences, 2005, Jan-28, Volume: 76, Issue:11

    Topics: Administration, Oral; Age Factors; Animals; Animals, Newborn; Body Weight; Female; Injections, Subcu

2005
Thyroid hormone regulates Galphai1 gene expression in the rat cerebellar cortex during post-natal development.
    Journal of neurochemistry, 2005, Volume: 92, Issue:2

    Topics: Animals; Binding Sites; Binding, Competitive; CCAAT-Enhancer-Binding Protein-beta; Cerebellar Cortex

2005
Effects of hypothyroidism induced by perinatal exposure to PTU on rat behavior and synaptic gene expression.
    Toxicology, 2005, Sep-01, Volume: 212, Issue:2-3

    Topics: Acoustic Stimulation; Animals; Animals, Newborn; Antithyroid Agents; Behavior, Animal; Cerebral Cort

2005
Alcohol consumption during gestation reduces the histamine and triiodothyronine content of rat immune cells.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54, Issue:12

    Topics: Alcohol Drinking; Animals; Ethanol; Female; Flow Cytometry; Granulocytes; Histamine; Lactation; Leuk

2005
[Local blood flow in the dorsal hippocampus and cerebellar cortex in progeny of iodine-deficient rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2006, Volume: 92, Issue:3

    Topics: Animals; Animals, Newborn; Cerebellar Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders

2006
[Influences of excess iodine on thyroid hormone concentrations in cerebrum of filial mice and intervention of selenium].
    Wei sheng yan jiu = Journal of hygiene research, 2006, Volume: 35, Issue:2

    Topics: Animals; Animals, Newborn; Cerebrum; Female; Iodine; Male; Mice; Mice, Inbred BALB C; Pregnancy; Pre

2006
Thyroid hormones induce sumoylation of the cold shock domain-containing protein PIPPin in developing rat brain and in cultured neurons.
    Endocrinology, 2007, Volume: 148, Issue:1

    Topics: Animals; Animals, Newborn; Antithyroid Agents; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Femal

2007
Effects of perinatal exposure to low-dose cadmium on thyroid hormone-related and sex hormone receptor gene expressions in brain of offspring.
    Neurotoxicology, 2007, Volume: 28, Issue:4

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cadmium; Dose-Response Relationship, Drug; Explorat

2007
[Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice].
    Wei sheng yan jiu = Journal of hygiene research, 2007, Volume: 36, Issue:2

    Topics: Animals; Animals, Newborn; Cerebrum; Female; Iodine; Male; Mice; Mice, Inbred BALB C; Pregnancy; Pre

2007
Developmental exposure to decabromodiphenyl ether (PBDE 209): effects on thyroid hormone and hepatic enzyme activity in male mouse offspring.
    Chemosphere, 2008, Volume: 70, Issue:4

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Female; Glucuronosy

2008
Immunoreactive somatostatin and beta-endorphin content in the brain of mature rats after neonatal exposure to propylthiouracil.
    Endocrinology, 1982, Volume: 110, Issue:6

    Topics: Animals; beta-Endorphin; Body Weight; Brain Chemistry; Endorphins; Female; Male; Pregnancy; Prenatal

1982
Iodine-induced alterations of thyroid function in newborn infants after prenatal and perinatal exposure to povidone iodine.
    The Journal of pediatrics, 1983, Volume: 102, Issue:6

    Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Iodides; Povidone; Povidone-Iodine; Preg

1983
The effect of 3,5,3'-triiodothyronine on phosphoenolpyruvate carboxykinase, fatty acid synthetase and malic enzyme activity of liver and brown fat of fetal and neonatal rats.
    Biology of the neonate, 1982, Volume: 41, Issue:1-2

    Topics: Adipose Tissue, Brown; Adrenal Cortex Hormones; Aging; Animals; Animals, Newborn; Fatty Acid Synthas

1982
Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats.
    Toxicology and applied pharmacology, 1995, Volume: 135, Issue:1

    Topics: Acoustic Stimulation; Animals; Antithyroid Agents; Aroclors; Audiometry; Chlorodiphenyl (54% Chlorin

1995
Effects of maternal ingestion of Aroclor 1254 (PCB) on the developmental pattern of oxygen consumption and body temperature in neonatal rats.
    Bulletin of environmental contamination and toxicology, 1995, Volume: 55, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Aroclors; Blood Gas Analysis; Body Temperature; Car

1995
Intrauterine food restriction is associated with obesity in young rats.
    The Journal of nutrition, 1993, Volume: 123, Issue:8

    Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Animals, Suckling; Body Weight; Disease Models, Anim

1993
Parturition and periparturient reproductive and metabolic hormone concentrations in prenatally androgenized beef heifers.
    Journal of animal science, 1995, Volume: 73, Issue:12

    Topics: Androgens; Animals; Birth Weight; Cattle; Estradiol; Estrus; Female; Gonadal Steroid Hormones; Insul

1995
Effects of prenatal androgenization and postnatal steroid treatment on growth hormone, insulin-like growth factor I and II, insulin, thyroxine, and triidothyronine concentrations in beef heifers.
    Journal of animal science, 1996, Volume: 74, Issue:2

    Topics: Animals; Birth Weight; Cattle; Drug Implants; Estrogens; Female; Growth Hormone; Hormones; Insulin;

1996
Prenatal treatment of fetal hypothyroidism: is there more than one option?
    Prenatal diagnosis, 1996, Volume: 16, Issue:5

    Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Gestational Age; Humans; Hyperthyroidism; Hypothyroidism

1996
Differential effects of hypothyroidism on Na-K-ATPase mRNA alpha isoforms in the developing rat brain.
    Journal of molecular neuroscience : MN, 1996,Fall, Volume: 7, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Brain; Enzyme Induction; Female; Gene Expression Regulation, Devel

1996
Tissue-specific regulation of medium-chain acyl-CoA dehydrogenase gene by thyroid hormones in the developing rat.
    The Biochemical journal, 1997, May-15, Volume: 324 ( Pt 1)

    Topics: Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Animals; Cell Nucleus; Female; Gene Expression Regu

1997
Effects of maternal exposure to chlorinated diphenyl ethers on thyroid hormone concentrations in maternal and juvenile rats.
    Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 1997, Volume: 32, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Suckling; Body Weight; Dose-Response Relationship, Drug; Eth

1997
Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:9

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Herni

1997
Effects of prenatal maternal TRH stimulation on the postnatal ability of neonatal piglets to cope with a cold challenge.
    Biology of the neonate, 1998, Volume: 73, Issue:6

    Topics: Adaptation, Physiological; Age Factors; Animals; Animals, Newborn; Cold Temperature; Female; Pregnan

1998
Effect of PTU treatment on histone acetylation pattern in the developing rat brain.
    Endocrine research, 1999, Volume: 25, Issue:1

    Topics: Acetylation; Aging; Animals; Animals, Newborn; Brain; Female; Histones; Pregnancy; Prenatal Exposure

1999
Antenatal glucocorticoids alter premature newborn lamb neuroendocrine and endocrine responses to hypoxia.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 279, Issue:3

    Topics: Angiotensin II; Animals; Animals, Newborn; Arginine Vasopressin; Atrial Natriuretic Factor; Betameth

2000
Regulation of microglial development: a novel role for thyroid hormone.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Mar-15, Volume: 21, Issue:6

    Topics: Animals; Brain; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Female; Hyperthyroidism;

2001
Thyroid hormone regulates oxidative phosphorylation in the cerebral cortex and striatum of neonatal rats.
    Journal of neurochemistry, 2001, Volume: 78, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Animals, Newborn; Antithyroid Agents; Carrier Proteins; Cerebral

2001
Thyroidal regulation of different isoforms of NaKATPase in glial cells of developing rat brain.
    Life sciences, 2001, Oct-05, Volume: 69, Issue:20

    Topics: Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Brain; Cells, Cultured; Female; Hy

2001
Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 66, Issue:1

    Topics: Animals; Body Weight; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Female; Glucuronosyltransfer

2002
Antithyroid drug treatment of Graves' disease in pregnancy: long-term effects on somatic growth, intellectual development and thyroid function of the offspring.
    Acta endocrinologica, 1990, Volume: 123, Issue:3

    Topics: Birth Weight; Carbimazole; Child; Drug Therapy, Combination; Female; Follow-Up Studies; Graves Disea

1990
Malic enzyme activity in the developing rat brain in relation to thyroid status.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1989, Volume: 7, Issue:2

    Topics: Animals; Body Weight; Brain; Female; Liver; Malate Dehydrogenase; Organ Size; Pregnancy; Prenatal Ex

1989
Response of the maternal, fetal, and neonatal pituitary-thyroid axis to thyrotropin-releasing hormone.
    Pediatric research, 1986, Volume: 20, Issue:10

    Topics: Female; Fetus; Humans; Infant, Newborn; Pregnancy; Prenatal Exposure Delayed Effects; Prolactin; Thy

1986
Effects of maternal treatment with corticosteroids, T3, TRH, and their combinations on lung function of ventilated preterm rabbits with and without surfactant treatments.
    The American review of respiratory disease, 1987, Volume: 136, Issue:4

    Topics: Animals; Betamethasone; Female; Fetal Organ Maturity; Lung; Pregnancy; Prenatal Exposure Delayed Eff

1987
Effects of anticonvulsant monotherapy in pregnancy on the newborn endocrine system. Preliminary data.
    Bollettino della Societa italiana di biologia sperimentale, 1985, Feb-28, Volume: 61, Issue:2

    Topics: Anticonvulsants; Endocrine System Diseases; Female; Follicle Stimulating Hormone; Humans; Infant, Ne

1985
Prenatal exposure of the fetal rat to excessive L-thyroxine or 3,5-dimethyl-3'-isopropyl-thyronine produces persistent changes in the thyroid control system.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:12

    Topics: Animals; Body Weight; Female; Fetus; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbre

1985