Page last updated: 2024-11-08

triiodothyronine and Deafness

triiodothyronine has been researched along with Deafness in 18 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Deafness: A general term for the complete loss of the ability to hear from both ears.

Research Excerpts

ExcerptRelevanceReference
"Pendred's syndrome is reported in three siblings."1.25Pituitary-thyroid function in Pendred's syndrome. ( Evered, DC; Gomez-Pan, A; Hall, R, 1974)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199013 (72.22)18.7374
1990's0 (0.00)18.2507
2000's3 (16.67)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ng, L3
Kelley, MW1
Forrest, D3
Peeters, RP1
Ma, M1
HOLLANDER, CS1
PROUT, TE1
RIENHOFF, M1
RUBEN, RJ1
ASPER, SP1
Oshima, A1
Suzuki, S1
Takumi, Y1
Hashizume, K1
Abe, S1
Usami, S1
Paggi, A1
Cassone, R1
Lucisano, V1
Chieco, P1
Dalmaso, S1
Danese, V1
Corsi, V1
Gauthier, K1
Plateroti, M1
Harvey, CB1
Williams, GR1
Weiss, RE1
Refetoff, S2
Willott, JF1
Sundin, V1
Roux, JP1
Malaval, L1
Hara, M1
Samarut, J1
Chassande, O1
Rüsch, A1
Amma, LL1
Nordström, K1
Erway, LC1
Vennström, B1
Chan, V1
Wang, C1
Yeung, RT1
Chopra, IJ1
Hershman, JM1
Hornabrook, RW1
Friis, J1
Johnsen, T1
Feldt-Rasmussen, U1
Bech, K1
Friis, T1
Greig, WR1
Gomez-Pan, A1
Evered, DC1
Hall, R1
Ibbertson, HK1
Ibberston, HK1
Yamamoto, M2
Sakurada, T2
Yamaguchi, T2
Yoshida, K2
Matsui, K1
Saito, S1
Kohonen, A1
Jauhiainen, T1
Liewendahl, K1
Tarkkanen, J1
Kaimio, M1
DeGroot, LJ1
Benard, B1
DeWind, LT1

Reviews

2 reviews available for triiodothyronine and Deafness

ArticleYear
Making sense with thyroid hormone--the role of T(3) in auditory development.
    Nature reviews. Endocrinology, 2013, Volume: 9, Issue:5

    Topics: Animals; Auditory Pathways; Cell Differentiation; Cochlea; Color Vision Defects; Deafness; Hair Cell

2013
Radionuclide evaluation of thyroid disease in children.
    Seminars in nuclear medicine, 1973, Volume: 3, Issue:1

    Topics: Adult; Child; Child, Preschool; Congenital Hypothyroidism; Deafness; Diagnosis, Differential; Goiter

1973

Other Studies

16 other studies available for triiodothyronine and Deafness

ArticleYear
The timecourse of apoptotic cell death during postnatal remodeling of the mouse cochlea and its premature onset by triiodothyronine (T3).
    Molecular and cellular endocrinology, 2015, May-15, Volume: 407

    Topics: Animals; Animals, Newborn; Apoptosis; Caspase 3; Deafness; Gene Expression Regulation, Developmental

2015
CONGENITAL DEAFNESS AND GOITER. STUDIES OF A PATIENT WITH A COCHLEAR DEFECT AND INADEQUATE FORMATION OF IODOTHYRONINES.
    The American journal of medicine, 1964, Volume: 37

    Topics: Cochlea; Congenital Abnormalities; Deafness; Diiodotyrosine; Goiter; Hearing Loss; Humans; Iodine Is

1964
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
    Journal of medical genetics, 2006, Volume: 43, Issue:6

    Topics: Animals; Carrier Proteins; Cochlea; Crystallins; Deafness; Humans; Membrane Proteins; Mice; Models,

2006
[Echocardiographic study of 2 cases of Pendred syndrome].
    Minerva medica, 1982, Apr-02, Volume: 73, Issue:14

    Topics: Adult; Deafness; Echocardiography; Female; Goiter; Humans; Male; Myxedema; Radionuclide Imaging; Syn

1982
Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
    Molecular and cellular biology, 2001, Volume: 21, Issue:14

    Topics: Animals; Bone Development; Cysteine Endopeptidases; Deafness; Down-Regulation; Embryonic and Fetal D

2001
Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene.
    Human molecular genetics, 2001, Nov-01, Volume: 10, Issue:23

    Topics: Animals; Body Weight; Cochlea; Deafness; DNA-Binding Proteins; Evoked Potentials, Auditory, Brain St

2001
Dissociated thyroxine, triiodothyronine and reverse triiodothyronine levels in patients with familial goitre due to iodide organification defects.
    Clinical endocrinology, 1979, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Congenital Hypothyroidism; Deafness; Female; Goiter; Humans; Iodine; Male; Pedigr

1979
Serum thyroid hormone and thyrotropin levels in subjects from endemic goiter regions of New Guinea.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Deafness; Female; Goiter, Endemic; Humans; Male; M

1975
Thyroid function in patients with Pendred's syndrome.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:2

    Topics: Adolescent; Adult; Aged; Autoantibodies; Deafness; Female; Goiter; Humans; Male; Middle Aged; Thyrog

1988
Pituitary-thyroid function in Pendred's syndrome.
    British medical journal, 1974, Apr-20, Volume: 2, Issue:5911

    Topics: Adult; Deafness; Female; Goiter; Humans; Iodine; Iodine Radioisotopes; Male; Pituitary Gland; Retina

1974
Himalayan goiter.
    Acta endocrinologica. Supplementum, 1973, Volume: 179

    Topics: Adolescent; Age Factors; Chromatography; Chromatography, Thin Layer; Deafness; Female; Goiter; Human

1973
Goitre and cretinism in the high Himalayas.
    The New Zealand medical journal, 1974, Dec-11, Volume: 80, Issue:529

    Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Deafness; Female; Goiter, Endemic; Humans; Hypo

1974
[Case of Pendred's syndrome].
    Horumon to rinsho. Clinical endocrinology, 1974, Volume: 22, Issue:4

    Topics: Child; Deafness; Feedback; Goiter; Humans; Male; Syndrome; Thyrotropin; Thyroxine; Triiodothyronine

1974
The changes of serum triiodothyronine, thyroxine and thyroid stimulating hormone in two cases of hypothyroidism with unusual complications.
    The Tohoku journal of experimental medicine, 1974, Volume: 112, Issue:4

    Topics: Child; Deafness; Exophthalmos; Goiter; Humans; Hypothyroidism; Male; Middle Aged; Myxedema; Radioimm

1974
Deafness in experimental hypo- and hyperthyroidism.
    The Laryngoscope, 1971, Volume: 81, Issue:6

    Topics: Animals; Audiometry; Deafness; Disease Models, Animal; Guinea Pigs; Hyperthyroidism; Hypothyroidism;

1971
Studies of a sibship with apparent hereditary resistance to the intracellular action of thyroid hormone.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:8

    Topics: Adolescent; Bone Diseases, Developmental; Child; Deafness; Erythrocytes; Female; Fibroblasts; Goiter

1972