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triiodothyronine and Cystinosis

triiodothyronine has been researched along with Cystinosis in 4 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Cystinosis: A metabolic disease characterized by the defective transport of CYSTINE across the lysosomal membrane due to mutation of a membrane protein cystinosin. This results in cystine accumulation and crystallization in the cells causing widespread tissue damage. In the KIDNEY, nephropathic cystinosis is a common cause of RENAL FANCONI SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"Eleven children with nephropathic cystinosis without clinical features of hyperthyroidism or hypothyroidism had elevated serum levels of immunoreactive TSH."1.26Pituitary resistance to thyroid hormone in cystinosis. ( Bercu, BB; Orloff, S; Schulman, JD, 1980)
"Children with nephropathic cystinosis exhibit marked growth retardation."1.26Endocrine studies in cystinosis: compensated primary hypothyroidism. ( Howley, PM; Lucky, AW; Megyesi, K; Schulman, JD; Spielberg, SP, 1977)
"Hypothyroidism is a common finding in cystinosis, and it is suggested that thyroxine treatment be started when the TSH concentration becomes raised."1.26Hypothyroidism in children with cystinosis. ( Burke, JR; Chantler, C; El-Bishti, MM; Maisey, MN, 1978)
"Compensated hypothyroidism is frequent in cystinosis and may be one factor in the severe growth retardation in this condition."1.26[Thyroid involvement in cystinosis]. ( Broyer, M; Czernichow, P; Lenoir, G; Rappaport, R; Roy, MP, 1978)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bercu, BB1
Orloff, S1
Schulman, JD2
Lucky, AW1
Howley, PM1
Megyesi, K1
Spielberg, SP1
Burke, JR1
El-Bishti, MM1
Maisey, MN1
Chantler, C1
Czernichow, P1
Lenoir, G1
Roy, MP1
Rappaport, R1
Broyer, M1

Other Studies

4 other studies available for triiodothyronine and Cystinosis

ArticleYear
Pituitary resistance to thyroid hormone in cystinosis.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 51, Issue:6

    Topics: Child; Child, Preschool; Cystinosis; Drug Resistance; Feedback; Female; Humans; Male; Pituitary Glan

1980
Endocrine studies in cystinosis: compensated primary hypothyroidism.
    The Journal of pediatrics, 1977, Volume: 91, Issue:2

    Topics: Child; Child, Preschool; Creatinine; Cystinosis; Female; Follicle Stimulating Hormone; Growth Hormon

1977
Hypothyroidism in children with cystinosis.
    Archives of disease in childhood, 1978, Volume: 53, Issue:12

    Topics: Adolescent; Child; Child, Preschool; Cystinosis; Humans; Hypothyroidism; Kidney Failure, Chronic; Th

1978
[Thyroid involvement in cystinosis].
    Archives francaises de pediatrie, 1978, Volume: 35, Issue:9

    Topics: Adolescent; Child; Child, Preschool; Cholesterol; Cystinosis; Female; Follow-Up Studies; Growth Diso

1978