triiodothyronine has been researched along with Critical Illness in 59 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We assessed the prognostic implications of low triiodothyronine (T3) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in critically ill patients with acute heart failure." | 7.80 | Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure. ( Chuang, CP; Jong, YS; Lo, HM; Wu, CY, 2014) |
| "To analyse the influence of selenium substitution on thyroid hormone metabolism in patients with severe sepsis." | 5.11 | Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients. ( Angstwurm, MW; Gaertner, R; Schopohl, J, 2004) |
| "We assessed the prognostic implications of low triiodothyronine (T3) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in critically ill patients with acute heart failure." | 3.80 | Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure. ( Chuang, CP; Jong, YS; Lo, HM; Wu, CY, 2014) |
| "The low plasma triiodothyronine (T3) observed during prolonged critical illness can be explained in part by suppressed hepatic deiodinase type I (D1) and increased D3 activity." | 3.74 | Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness. ( Darras, VM; Debaveye, Y; Ellger, B; Mebis, L; Van den Berghe, G, 2008) |
| "One hundred and eighty patients had serum thyrotropin, total triiodothyronine and free thyroxine concentrations measured within 3 h of admission to the Intensive Therapy Unit to assess whether thyroid function tests could predict outcome in critical illness." | 3.69 | Relationship of admission thyroid function tests to outcome in critical illness. ( Beckett, GJ; Drummond, GB; Ray, DC; Wilkinson, E, 1995) |
| "To evaluate the 24-h pattern of serum thyrotropin (TSH) in critically ill patients, we measured serum concentrations of TSH in blood samples collected every 2 h for 24 h from nine patients (six with malignancy, two with liver cirrhosis, one with chronic renal failure), who had subnormal levels of both triiodothyronine (T3) and thyroxine (T4), in the absence of history, symptoms or signs of thyroid disease." | 3.68 | Alterations in circadian rhythm of serum thyrotropin in critically ill patients. ( Custro, N; Notarbartolo, A; Scafidi, V, 1992) |
| "The inflammatory response of critical illness is accompanied by nonthyroidal illness syndrome (NTIS)." | 2.94 | Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation. ( Bianco, AC; Bocco, BMLC; Braunschweig, CA; Fernandes, GW; Fonseca, TL; Freels, S; Lateef, O; McKeever, L; Mozer, M; Nowak, K; Peterson, SJ; Roehl, K, 2020) |
| "Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support), ClinicalTrials." | 2.94 | Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial. ( Armaganidis, A; Kostopanagiotou, G; Mourouzis, I; Pantos, C; Trikas, A; Tseti, I, 2020) |
| "Both critical illness and fasting induce low circulating thyroid hormone levels in the absence of a rise in TSH, a constellation-labeled nonthyroidal illness syndrome (NTI)." | 2.78 | Impact of early nutrient restriction during critical illness on the nonthyroidal illness syndrome and its relation with outcome: a randomized, controlled clinical study. ( Boelen, A; Casaer, MP; Langouche, L; Marques, M; Van den Berghe, G; Vander Perre, S; Wouters, PJ, 2013) |
| "In a rabbit model of prolonged critical illness, gene expression levels of MCT8 in liver and of MCT10 in skeletal muscle were increased as compared with healthy controls." | 2.74 | Expression of thyroid hormone transporters during critical illness. ( D'Hoore, A; Darras, VM; Debaveye, Y; Ellger, B; Langouche, L; Mebis, L; Paletta, D; Van den Berghe, G; Visser, TJ, 2009) |
| "Critical illness is often associated with reduced TSH and thyroid hormone secretion as well as marked changes in peripheral thyroid hormone metabolism, resulting in low serum T(3) and high rT(3) levels." | 2.71 | Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. ( Kaptein, E; Peeters, RP; Van den Berghe, G; van Toor, H; Visser, TJ; Wouters, PJ, 2003) |
| "Critical illness is associated with reduced TSH and thyroid hormone secretion, and with changes in peripheral thyroid hormone metabolism, resulting in low serum T3 and high rT3." | 2.71 | Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities. ( Kaptein, E; Peeters, RP; Van den Berghe, G; van Toor, H; Visser, TJ; Wouters, PJ, 2005) |
| "The catabolic state of prolonged critical illness is associated with a low activity of the thyrotropic and the somatotropic axes." | 2.69 | Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues. ( Baxter, RC; Bouillon, R; Bowers, CY; de Zegher, F; Lauwers, P; Schetz, M; Van den Berghe, G; Van der Vorst, E; Veldhuis, JD; Verwaest, C; Wouters, P, 1998) |
| "During prolonged critical illness, mean night-time serum concentrations of TSH (1." | 2.68 | Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues. ( Bouillon, R; Bowers, CY; de Zegher, F; Gouwy, S; Lauwers, P; Schetz, M; Stockman, W; Van den Berghe, G; Veldhuis, JD; Weekers, F; Wouters, P, 1997) |
| "The sick euthyroid syndrome is a poorly understood hallmark of critical illness." | 2.67 | Dopamine and the sick euthyroid syndrome in critical illness. ( de Zegher, F; Lauwers, P; Van den Berghe, G, 1994) |
| "Whether this is an adaptive response in critical illness or contributes to progressive disease has remained controversial." | 2.61 | Thyroid Hormones in Critical Illness. ( Maiden, MJ; Torpy, DJ, 2019) |
| "Decisions surrounding the timing and dosing of nutrition support are made for thousands of ICU patients daily and yet remain a topic of controversy." | 2.58 | Feeding During Phases of Altered Mitochondrial Activity: A Theory. ( Bonini, M; Braunschweig, C; McKeever, L, 2018) |
| "With increase in severity of critical illness assessed by APACHE III, TFT, that is, TT3, TT4, and FT3 levels were decreasing, suggestive of increasing non-thyroidal illness in critically ill patients." | 1.72 | Study of Thyroid Functions in critically ill Patients admitted in Medical Intensive Care Unit and its Correlation with Critical Care Scoring Acute Physiology and Chronic Health Evaluation III. ( Chaudhary, G; Kanchi, G; Mahashabde, M; Murukoti, SR; Patil, R, 2022) |
| "Sepsis and septic shock result in impaired microcirculation and red blood cell rheology which lead to tissue hypoxia and multi-organ failure." | 1.62 | Acute triiodothyronine treatment and red blood cell sedimentation rate (ESR) in critically ill COVID-19 patients: A novel association? ( Apostolaki, V; Kokkinos, L; Mourouzis, I; Pantos, C; Trikas, A, 2021) |
| "Alterations in thyroid hormones during critical illness, known as non-thyroidal illness syndrome (NTIS), were suggested to have a prognostic value." | 1.51 | [Prevalence and prognostic value of non-thyroidal illness syndrome among critically ill children]. ( El-Dihemey, MA; El-Ella, SSA; El-Mekkawy, MS, 2019) |
| " A dose-response relationship was identifiable." | 1.48 | Triiodothyronine replacement in critically ill adults with non-thyroidal illness syndrome. ( Haddara, WMR; Kanji, S; Kim, J; Meggison, H; Neilipovitz, B; Neilipovitz, J; Patel, R; Pittman, M, 2018) |
| "For patients with critical illness, the early two-step thyroid screening strategy (starting with an isolated TSH determination between 24 and 48h after admission) led to a saving of 50% in fT4 and fT3 tests, with a false-negative rate of 1." | 1.43 | Two-step thyroid screening strategy in the critical patient. ( Barcelo, A; Bauça, JM; Elorza, MA; Morell-Garcia, D, 2016) |
| "Critical illness in patients with polytrauma leaded to trauma severity-dependent alterations of the thyroid axis response early after injury." | 1.42 | Dynamic neuroendocrine changes in critically ill patients with polytrauma. ( Galusova, A; Imrich, R; Mackova, J; Majek, M; Meskova, M; Pauliny, M; Penesova, A; Vlcek, M, 2015) |
| "Both starvation and critical illness are hallmarked by changes in circulating thyroid hormone parameters with typically low T(3) concentrations in the absence of elevated TSH." | 1.38 | Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study. ( Darras, VM; Derde, S; Eerdekens, A; Güiza, F; Langouche, L; Mebis, L; Princen, L; Van den Berghe, G; Vanhorebeek, I; Vanwijngaerden, YM, 2012) |
| "Chronic obstructive pulmonary disease (COPD) itself causes hormonal changes." | 1.36 | The endocrinologic changes in critically ill chronic obstructive pulmonary disease patients. ( Akalin, S; Akbaş, T; Celikel, T; Karakurt, S; Unlügüzel, G, 2010) |
| "Hypothyroidism is an uncommon cause of failure to wean in patients receiving PMV (with an incidence of 3%)." | 1.32 | Hypothyroidism and failure to wean in patients receiving prolonged mechanical ventilation at a regional weaning center. ( Datta, D; Scalise, P, 2004) |
| "To induce prolonged critical illness, a template controlled 15% deep dermal burn injury was imposed under combined general and regional (paravertebral) anesthesia." | 1.31 | A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response. ( Bowers, CY; Coopmans, W; Michalaki, M; Van den Berghe, G; Van Herck, E; Veldhuis, JD; Weekers, F, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (22.03) | 18.2507 |
| 2000's | 22 (37.29) | 29.6817 |
| 2010's | 15 (25.42) | 24.3611 |
| 2020's | 9 (15.25) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, X | 1 |
| Sun, J | 1 |
| Hong, L | 1 |
| Song, X | 1 |
| Zhang, C | 1 |
| Liu, Y | 1 |
| Liu, H | 1 |
| Li, G | 1 |
| Mu, X | 1 |
| Okoye, C | 1 |
| Niccolai, F | 1 |
| Rogani, S | 1 |
| Lemmi, B | 1 |
| Peta, U | 1 |
| Del Vecchio, S | 1 |
| Morelli, V | 1 |
| Caraccio, N | 1 |
| Calsolaro, V | 1 |
| Monzani, F | 1 |
| Mahashabde, M | 1 |
| Murukoti, SR | 1 |
| Chaudhary, G | 1 |
| Kanchi, G | 1 |
| Patil, R | 1 |
| Besci, T | 1 |
| Besci, Ö | 1 |
| Arslan, G | 1 |
| Ilgaz, H | 1 |
| Prencuva, P | 1 |
| Özdemir, G | 1 |
| Abacı, A | 1 |
| Demir, K | 1 |
| McKeever, L | 2 |
| Peterson, SJ | 1 |
| Lateef, O | 1 |
| Freels, S | 1 |
| Fonseca, TL | 1 |
| Bocco, BMLC | 1 |
| Fernandes, GW | 1 |
| Roehl, K | 1 |
| Nowak, K | 1 |
| Mozer, M | 1 |
| Bianco, AC | 1 |
| Braunschweig, CA | 1 |
| Pantos, C | 3 |
| Tseti, I | 2 |
| Mourouzis, I | 3 |
| Kostopanagiotou, G | 1 |
| Armaganidis, A | 1 |
| Trikas, A | 2 |
| Gao, W | 1 |
| Guo, W | 1 |
| Guo, Y | 1 |
| Shi, M | 1 |
| Dong, G | 1 |
| Wang, G | 1 |
| Ge, Q | 1 |
| Zhu, J | 1 |
| Zhou, X | 1 |
| Apostolaki, V | 1 |
| Kokkinos, L | 1 |
| El-Ella, SSA | 1 |
| El-Mekkawy, MS | 1 |
| El-Dihemey, MA | 1 |
| Kanji, S | 1 |
| Neilipovitz, J | 1 |
| Neilipovitz, B | 1 |
| Kim, J | 1 |
| Haddara, WMR | 1 |
| Pittman, M | 1 |
| Meggison, H | 1 |
| Patel, R | 1 |
| Bonini, M | 1 |
| Braunschweig, C | 1 |
| Wang, YF | 1 |
| Heng, JF | 1 |
| Yan, J | 1 |
| Dong, L | 1 |
| Zhang, D | 1 |
| Gao, L | 1 |
| Ye, H | 1 |
| Chi, R | 1 |
| Wang, L | 1 |
| Hu, L | 1 |
| Ouyang, X | 1 |
| Hou, Y | 1 |
| Deng, Y | 1 |
| Long, Y | 1 |
| Xiong, W | 1 |
| Chen, C | 1 |
| Maiden, MJ | 1 |
| Torpy, DJ | 1 |
| Jäger, F | 1 |
| Willenberg, HS | 1 |
| Chuang, CP | 1 |
| Jong, YS | 1 |
| Wu, CY | 1 |
| Lo, HM | 1 |
| Galusova, A | 1 |
| Pauliny, M | 1 |
| Majek, M | 1 |
| Mackova, J | 1 |
| Meskova, M | 1 |
| Vlcek, M | 1 |
| Imrich, R | 1 |
| Penesova, A | 1 |
| Morell-Garcia, D | 1 |
| Bauça, JM | 1 |
| Elorza, MA | 1 |
| Barcelo, A | 1 |
| Gärtner, R | 1 |
| Mebis, L | 4 |
| Paletta, D | 1 |
| Debaveye, Y | 2 |
| Ellger, B | 2 |
| Langouche, L | 3 |
| D'Hoore, A | 1 |
| Darras, VM | 5 |
| Visser, TJ | 7 |
| Van den Berghe, G | 15 |
| Shih, JL | 1 |
| Agus, MS | 1 |
| Derde, S | 2 |
| Vanhorebeek, I | 2 |
| Ververs, EJ | 1 |
| Vanhees, I | 1 |
| Van Herck, E | 2 |
| Larsson, L | 1 |
| Suvarna, JC | 1 |
| Fande, CN | 1 |
| Akbaş, T | 1 |
| Karakurt, S | 1 |
| Unlügüzel, G | 1 |
| Celikel, T | 1 |
| Akalin, S | 1 |
| Rocco, M | 1 |
| Pro, S | 1 |
| Alessandri, E | 1 |
| Vicenzini, E | 1 |
| Mecarelli, O | 1 |
| Eerdekens, A | 1 |
| Güiza, F | 1 |
| Princen, L | 1 |
| Vanwijngaerden, YM | 1 |
| Vander Perre, S | 1 |
| Marques, M | 1 |
| Boelen, A | 1 |
| Wouters, PJ | 4 |
| Casaer, MP | 1 |
| Peeters, RP | 4 |
| Kaptein, E | 3 |
| van Toor, H | 4 |
| Angstwurm, MW | 1 |
| Schopohl, J | 1 |
| Gaertner, R | 1 |
| Datta, D | 1 |
| Scalise, P | 1 |
| Simpson, J | 1 |
| Williams, FL | 1 |
| Delahunty, C | 1 |
| Wu, SY | 1 |
| Ogston, SA | 1 |
| Hume, R | 1 |
| van der Geyten, S | 1 |
| Hulst, JM | 1 |
| van Goudoever, JB | 1 |
| Tibboel, D | 1 |
| Joosten, KF | 1 |
| Fliers, E | 2 |
| Unmehopa, UA | 1 |
| Alkemade, A | 1 |
| Niemczyk, S | 1 |
| Woźniacki, L | 1 |
| Thijssen-Timmer, DC | 1 |
| Wouters, P | 3 |
| Weekers, F | 3 |
| Wiersinga, WM | 1 |
| Bakker, O | 1 |
| Karbownik-Lewińska, M | 1 |
| Kokoszko, A | 1 |
| Jozefiak, M | 1 |
| Lewiński, A | 1 |
| Anand, NK | 1 |
| Chandra, V | 1 |
| Sinha, RS | 1 |
| Chellani, H | 1 |
| de Zegher, F | 4 |
| Lauwers, P | 4 |
| Rothwell, PM | 1 |
| Udwadia, ZF | 1 |
| Lawler, PG | 1 |
| Arem, R | 1 |
| Wiener, GJ | 1 |
| Kaplan, SG | 1 |
| Kim, HS | 1 |
| Reichlin, S | 1 |
| Kaplan, MM | 1 |
| Jarek, MJ | 1 |
| Legare, EJ | 1 |
| McDermott, MT | 1 |
| Merenich, JA | 1 |
| Kollef, MH | 1 |
| Ray, DC | 1 |
| Drummond, GB | 1 |
| Wilkinson, E | 1 |
| Beckett, GJ | 1 |
| Vlasselaers, D | 1 |
| Schetz, M | 3 |
| Verwaest, C | 2 |
| Ferdinande, P | 1 |
| Loh, KC | 1 |
| Eng, PC | 1 |
| Veldhuis, JD | 3 |
| Gouwy, S | 1 |
| Stockman, W | 1 |
| Bouillon, R | 2 |
| Bowers, CY | 3 |
| Vogeser, M | 1 |
| Jacob, K | 1 |
| Baxter, RC | 1 |
| Van der Vorst, E | 1 |
| Kabadi, UM | 1 |
| Stathatos, N | 1 |
| Levetan, C | 1 |
| Burman, KD | 1 |
| Wartofsky, L | 1 |
| Coopmans, W | 1 |
| Michalaki, M | 1 |
| Cogo, PE | 1 |
| Carnielli, VP | 1 |
| Rosso, F | 1 |
| Cesarone, A | 1 |
| Giordano, G | 1 |
| Faggian, D | 1 |
| Plebani, M | 1 |
| Barreca, A | 1 |
| Zacchello, F | 1 |
| Umpierrez, GE | 1 |
| Custro, N | 1 |
| Scafidi, V | 1 |
| Notarbartolo, A | 1 |
| Maldonado, LS | 1 |
| Murata, GH | 1 |
| Hershman, JM | 1 |
| Braunstein, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feeding the Critically Ill During Phases of Altered Redox Status (FEDOX): a Prospective Randomized Trial[NCT03085615] | 35 participants (Actual) | Interventional | 2017-03-15 | Completed | |||
| Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support)[NCT04348513] | Phase 2 | 5 participants (Actual) | Interventional | 2020-05-29 | Terminated (stopped due to Due to specific inclusion criteria no more subjects could be enrolled.) | ||
| Impact of Early Parenteral Nutrition Completing Enteral Nutrition in Adult Critically Ill Patients[NCT00512122] | Phase 4 | 4,640 participants (Actual) | Interventional | 2007-08-31 | Active, not recruiting | ||
| Thyroid Function in Term and Near Term Infants With Respiratory Distress and Its' Relation to Severity of Illness[NCT00293956] | 20 participants (Actual) | Observational | 2006-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for triiodothyronine and Critical Illness
| Article | Year |
|---|---|
Feeding During Phases of Altered Mitochondrial Activity: A Theory.
Topics: Apoptosis; Critical Care; Critical Illness; Electron Transport; Energy Metabolism; Humans; Mitochond | 2018 |
Thyroid Hormones in Critical Illness.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Critical Care; Critical Illness; Euthyroid | 2019 |
[Hormones and the critically ill].
Topics: Blood Glucose; Critical Illness; Glucocorticoids; Hormones; Humans; Prognosis; Survival Rate; Triiod | 2013 |
Selenium and thyroid hormone axis in critical ill states: an overview of conflicting view points.
Topics: Animals; Antioxidants; Critical Illness; Humans; Iodide Peroxidase; Selenium; Selenoproteins; Thyroi | 2009 |
Thyroid function in the critically ill newborn and child.
Topics: Animals; Cardiac Surgical Procedures; Child; Child, Preschool; Critical Illness; Humans; Hypothyroid | 2009 |
The hypothalamus-pituitary-thyroid axis in critical illness.
Topics: Animals; Critical Illness; Cytokines; Humans; Hypothalamo-Hypophyseal System; Iodide Peroxidase; Thy | 2009 |
Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland.
Topics: Critical Illness; Depression; Feedback, Physiological; Humans; Hypothalamus; Iodide Peroxidase; Iodo | 2006 |
[Thyroid hormones disturbances in critical ill patients--low T3 syndrome].
Topics: Critical Illness; Diagnosis, Differential; Endocrine System Diseases; Euthyroid Sick Syndromes; Huma | 2005 |
The controversy of the treatment of critically ill patients with thyroid hormone.
Topics: Animals; Critical Care; Critical Illness; Heart Diseases; Humans; Infections; Respiration; Shock; Th | 2001 |
Euthyroid sick syndrome.
Topics: Critical Illness; Euthyroid Sick Syndromes; Humans; Starvation; Thyroid Hormones; Thyroxine; Triiodo | 2002 |
11 trials available for triiodothyronine and Critical Illness
| Article | Year |
|---|---|
Higher Caloric Exposure in Critically Ill Patients Transiently Accelerates Thyroid Hormone Activation.
Topics: Critical Illness; Energy Intake; Enteral Nutrition; Euthyroid Sick Syndromes; Female; Humans; Male; | 2020 |
Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betacoronavirus; Coronavirus Infections; COVID-19; COVID | 2020 |
Expression of thyroid hormone transporters during critical illness.
Topics: Aged; Amino Acid Transport Systems, Neutral; Animals; Base Sequence; Critical Illness; Disease Model | 2009 |
Impact of early nutrient restriction during critical illness on the nonthyroidal illness syndrome and its relation with outcome: a randomized, controlled clinical study.
Topics: Aged; Critical Care; Critical Illness; Fasting; Female; Food Deprivation; Humans; Leptin; Male; Midd | 2013 |
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients.
Topics: Aged; Aged, 80 and over; Biopsy; Critical Illness; Humans; Hyperglycemia; Hypoglycemic Agents; Insul | 2003 |
Selenium substitution has no direct effect on thyroid hormone metabolism in critically ill patients.
Topics: Antioxidants; APACHE; Critical Illness; Female; Glutathione; Humans; Iodide Peroxidase; Male; Middle | 2004 |
Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities.
Topics: Aged; Biomarkers; Biopsy; Critical Care; Critical Illness; Female; Humans; Hypoglycemic Agents; Insu | 2005 |
Dopamine and the sick euthyroid syndrome in critical illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Depression, Chemical; Dopamine; Euthyr | 1994 |
Thyrotropin-releasing hormone in critical illness: from a dopamine-dependent test to a strategy for increasing low serum triiodothyronine, prolactin, and growth hormone concentrations.
Topics: Adolescent; Adult; Aged; Critical Illness; Dopamine; Dose-Response Relationship, Drug; Female; Growt | 1996 |
Thyrotrophin and prolactin release in prolonged critical illness: dynamics of spontaneous secretion and effects of growth hormone-secretagogues.
Topics: Adult; Aged; Critical Illness; Cross-Over Studies; Female; Growth Hormone-Releasing Hormone; Half-Li | 1997 |
Neuroendocrinology of prolonged critical illness: effects of exogenous thyrotropin-releasing hormone and its combination with growth hormone secretagogues.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Growth Hormone-Releasing Hormone; Human Gr | 1998 |
38 other studies available for triiodothyronine and Critical Illness
| Article | Year |
|---|---|
Decreased triiodothyronine (T3) as a predictor for prolonged mechanical ventilation in critically ill patients with cardiac surgery.
Topics: Adult; Cardiac Surgical Procedures; Cohort Studies; Critical Illness; Humans; Respiration, Artificia | 2022 |
Is non-thyroidal illness syndrome (NTIS) a clinical predictor of COVID-19 mortality in critically ill oldest old patients?
Topics: Aged, 80 and over; COVID-19; Critical Illness; Euthyroid Sick Syndromes; Humans; Thyrotropin; Triiod | 2022 |
Study of Thyroid Functions in critically ill Patients admitted in Medical Intensive Care Unit and its Correlation with Critical Care Scoring Acute Physiology and Chronic Health Evaluation III.
Topics: APACHE; Critical Care; Critical Illness; Humans; Intensive Care Units; Thyroid Hormones; Thyrotropin | 2022 |
Biochemical indicators of euthyroid sick syndrome in critically ill children.
Topics: Albumins; Child; Critical Illness; Euthyroid Sick Syndromes; Humans; Lactates; Thyroid Function Test | 2022 |
Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial.
Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Humans; Pandemics; Pneumonia, V | 2020 |
Thyroid hormone concentrations in severely or critically ill patients with COVID-19.
Topics: Adult; Aged; Aged, 80 and over; Cause of Death; China; Comorbidity; COVID-19; Critical Illness; Fema | 2021 |
Acute triiodothyronine treatment and red blood cell sedimentation rate (ESR) in critically ill COVID-19 patients: A novel association?
Topics: Blood Sedimentation; COVID-19; Critical Illness; Erythrocytes; Humans; SARS-CoV-2; Sepsis; Shock, Se | 2021 |
[Prevalence and prognostic value of non-thyroidal illness syndrome among critically ill children].
Topics: Adolescent; Child; Child, Preschool; Critical Illness; Euthyroid Sick Syndromes; Female; Humans; Inf | 2019 |
Triiodothyronine replacement in critically ill adults with non-thyroidal illness syndrome.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Female; Hormone Replacement Therapy; Humans; Male; | 2018 |
Relationship between disease severity and thyroid function in Chinese patients with euthyroid sick syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; APACHE; China; Critical Illness; Euthyroid Sick Syndrome | 2018 |
Impact of thyroid function on cystatin C in detecting acute kidney injury: a prospective, observational study.
Topics: Acute Kidney Injury; Adult; APACHE; Area Under Curve; Creatinine; Critical Illness; Cystatin C; Earl | 2019 |
Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure.
Topics: Aged; Aged, 80 and over; Comorbidity; Coronary Artery Disease; Critical Illness; Diabetic Angiopathi | 2014 |
Dynamic neuroendocrine changes in critically ill patients with polytrauma.
Topics: Adult; APACHE; Calcitonin; Calcitonin Gene-Related Peptide; Cohort Studies; Critical Illness; Euthyr | 2015 |
Two-step thyroid screening strategy in the critical patient.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Critical Illness; Female; Follow-Up Studies; | 2016 |
Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits.
Topics: Actins; Animals; Blood Glucose; Body Weight; Critical Illness; Disease Models, Animal; Glucose; Hype | 2010 |
Serum thyroid hormone profile in critically Ill children.
Topics: Case-Control Studies; Child; Child, Preschool; Critical Illness; Euthyroid Sick Syndromes; Humans; I | 2009 |
The endocrinologic changes in critically ill chronic obstructive pulmonary disease patients.
Topics: Acute Disease; Aged; Aged, 80 and over; APACHE; Critical Illness; Female; Follicle Stimulating Hormo | 2010 |
Nonconvulsive status epilepticus induced by acute hypothyroidism in a critically ill patient.
Topics: Acute Disease; Aged; Critical Illness; Female; Humans; Hypothyroidism; Intensive Care Units; Postope | 2011 |
Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study.
Topics: Animals; Constitutive Androstane Receptor; Critical Illness; Disease Models, Animal; Dithiothreitol; | 2012 |
Hypothyroidism and failure to wean in patients receiving prolonged mechanical ventilation at a regional weaning center.
Topics: Comorbidity; Critical Illness; Female; Humans; Hypothyroidism; Male; Respiratory Insufficiency; Retr | 2004 |
Serum thyroid hormones in preterm infants and relationships to indices of severity of intercurrent illness.
Topics: Age Factors; Birth Weight; Cohort Studies; Critical Illness; Fetal Blood; Gestational Age; Humans; I | 2005 |
Tissue thyroid hormone levels in critical illness.
Topics: Aged; Critical Illness; Female; Humans; Insulin; Iodide Peroxidase; Liver; Male; Middle Aged; Monoca | 2005 |
Hormone levels in children during the first week of ICU-admission: is there an effect of adequate feeding?
Topics: Adolescent; Biomarkers; C-Reactive Protein; Child; Child, Preschool; Critical Illness; Female; Human | 2006 |
Thyroid hormone receptor isoform expression in livers of critically ill patients.
Topics: Aged; Critical Illness; Humans; Iodide Peroxidase; Liver; Male; Middle Aged; RNA, Messenger; Thyroid | 2007 |
Significance of increased lipid peroxidation in critically ill patients.
Topics: Aged; Case-Control Studies; Critical Illness; Female; Humans; Lipid Peroxidation; Male; Middle Aged; | 2007 |
Regulation of tissue iodothyronine deiodinase activity in a model of prolonged critical illness.
Topics: Animals; Critical Illness; Disease Models, Animal; Iodide Peroxidase; Kidney; Liver; Male; Molecular | 2008 |
Evaluation of thyroid functions in critically ill infants.
Topics: Adaptation, Physiological; Blood Proteins; C-Reactive Protein; Case-Control Studies; Critical Illnes | 1994 |
Thyrotropin concentration predicts outcome in critical illness.
Topics: Critical Care; Critical Illness; Female; Humans; Hydrocortisone; Male; Middle Aged; Predictive Value | 1993 |
Reduced tissue thyroid hormone levels in fatal illness.
Topics: Adult; Child; Critical Illness; Female; Humans; Male; Middle Aged; Osmolar Concentration; Thyroxine; | 1993 |
Endocrine profiles for outcome prediction from the intensive care unit.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Colorado; Critical Illness; Female; Hormones; Hospit | 1993 |
Relationship of admission thyroid function tests to outcome in critical illness.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Critical Care; Critical Illness; Dopamine; F | 1995 |
Prevalence and prognostic relevance of sick euthyroid syndrome in a medical intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Cohort Studies; Critical Care; Critical Illness; | 1995 |
Measurement of free triiodothyronine in intensive care patients--comparison of two routine methods.
Topics: Aged; Aged, 80 and over; Critical Illness; Female; Humans; Intensive Care Units; Male; Middle Aged; | 1997 |
Thyrotropin dysregulation during a non-thyroidal illness: transient hypothalamic hypothyroidism?
Topics: Aged; Aged, 80 and over; Critical Illness; Humans; Hypothalamus; Hypothyroidism; Kinetics; Male; Mid | 2001 |
A novel in vivo rabbit model of hypercatabolic critical illness reveals a biphasic neuroendocrine stress response.
Topics: Animals; Body Weight; Critical Illness; Disease Models, Animal; Growth Hormone; Hemodynamics; Male; | 2002 |
Protein turnover, lipolysis, and endogenous hormonal secretion in critically ill children.
Topics: C-Peptide; Carbon Radioisotopes; Child, Preschool; Critical Illness; Glycerol; Growth Hormone; Human | 2002 |
Alterations in circadian rhythm of serum thyrotropin in critically ill patients.
Topics: Adult; Aged; Circadian Rhythm; Critical Illness; Female; Humans; Kidney Failure, Chronic; Liver Cirr | 1992 |
Do thyroid function tests independently predict survival in the critically ill?
Topics: Critical Illness; Humans; Prognosis; Radioimmunoassay; Regression Analysis; Risk Factors; Sensitivit | 1992 |