triiodothyronine has been researched along with Craniofacial Abnormalities in 2 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Craniofacial Abnormalities: Congenital structural deformities, malformations, or other abnormalities of the cranium and facial bones.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Heterozygous mutations in the thyroid hormone receptor alpha (THRA) gene cause resistance to thyroid hormone alpha (RTHα), a disease characterized by variable manifestations reminiscent of untreated congenital hypothyroidism but a raised triiodothyronine/thyroxine ratio and normal thyrotropin levels." | 3.85 | In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish. ( Carra, S; Cotelli, F; Marelli, F; Persani, L; Rurale, G, 2017) |
| "Craniofacial abnormalities including: microcephaly, underdeveloped maxilla, micrognathia, high arched palate, malocclusion, down-slanting palpebral fissures, thick eyelashes and full eyebrows." | 1.42 | Rubinstein-Taybi Syndrome in a 19-years old boy. ( Przedborska, A; Raczkowski, JW; Wilmańska, I; Zwierzchowski, TJ, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zwierzchowski, TJ | 1 |
| Przedborska, A | 1 |
| Wilmańska, I | 1 |
| Raczkowski, JW | 1 |
| Marelli, F | 1 |
| Carra, S | 1 |
| Rurale, G | 1 |
| Cotelli, F | 1 |
| Persani, L | 1 |
2 other studies available for triiodothyronine and Craniofacial Abnormalities
| Article | Year |
|---|---|
Rubinstein-Taybi Syndrome in a 19-years old boy.
Topics: Abnormalities, Multiple; Craniofacial Abnormalities; CREB-Binding Protein; Foot Deformities; Hand De | 2015 |
In vivo Functional Consequences of Human THRA Variants Expressed in the Zebrafish.
Topics: Anemia; Animals; Animals, Genetically Modified; Brain Edema; Congenital Hypothyroidism; Craniofacial | 2017 |