triiodothyronine has been researched along with Cirrhosis in 9 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 7.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "By preventing isoprenaline induced myocardial injury and fibrosis, amiodarone may have a cardioprotective role." | 7.69 | Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone. ( Cespedes, C; Dussaillant, G; Jalil, JE, 1994) |
| "Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury." | 5.62 | Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021) |
| "Severe cardiovascular diseases, such as myocardial infarction or heart failure, can alter thyroid hormone (TH) secretion and peripheral conversion, leading to low triiodothyronine (T3) syndrome." | 4.02 | Thyroid hormone mediates cardioprotection against postinfarction remodeling and dysfunction through the IGF-1/PI3K/AKT signaling pathway. ( Liao, X; Liu, L; Ruan, H; Yang, B; Zeng, B; Zhang, C, 2021) |
| " The aim of this study was therefore to evaluate the effect of propylthiouracil (PTU), and of the hypothyroidism induced by it, on the development of cutaneous and pulmonary fibrosis in the oxidant stress murine model of SSc." | 3.79 | Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis. ( Altavilla, D; Atteritano, M; Bagnato, G; Bitto, A; Cinquegrani, M; Irrera, N; Pizzino, G; Roberts, W; Saitta, A; Sangari, D; Squadrito, F, 2013) |
| "By preventing isoprenaline induced myocardial injury and fibrosis, amiodarone may have a cardioprotective role." | 3.69 | Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone. ( Cespedes, C; Dussaillant, G; Jalil, JE, 1994) |
| "Triiodothyronine (T3) has been shown to exert a defensive role in many pulmonary diseases, however, rare data are available regarding the role of T3 on silica-induced injury." | 1.62 | Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice. ( Chen, W; Fan, L; Gan, S; Ma, J; Wang, B; Wang, D; Xie, Y; Yang, M; Yu, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, Z | 1 |
| Wang, H | 1 |
| Zhang, X | 1 |
| Song, M | 1 |
| Yao, S | 1 |
| Jiang, P | 1 |
| Liu, D | 1 |
| Wang, Z | 1 |
| Lv, H | 1 |
| Li, R | 1 |
| Hong, Y | 1 |
| Dai, J | 1 |
| Hu, Y | 1 |
| Zhao, G | 1 |
| Zeng, B | 1 |
| Liao, X | 1 |
| Liu, L | 1 |
| Zhang, C | 1 |
| Ruan, H | 1 |
| Yang, B | 1 |
| Yang, M | 1 |
| Wang, D | 1 |
| Gan, S | 1 |
| Wang, B | 1 |
| Yu, L | 1 |
| Xie, Y | 1 |
| Fan, L | 1 |
| Ma, J | 1 |
| Chen, W | 1 |
| Teixeira, RB | 1 |
| Zimmer, A | 1 |
| de Castro, AL | 1 |
| Carraro, CC | 1 |
| Casali, KR | 1 |
| Dias, IGM | 1 |
| Godoy, AEG | 1 |
| Litvin, IE | 1 |
| Belló-Klein, A | 1 |
| da Rosa Araujo, AS | 1 |
| Zhang, K | 1 |
| Tang, YD | 1 |
| Zhang, Y | 1 |
| Ojamaa, K | 1 |
| Li, Y | 1 |
| Saini, AS | 1 |
| Carrillo-Sepulveda, MA | 1 |
| Rajagopalan, V | 1 |
| Gerdes, AM | 1 |
| Bagnato, G | 2 |
| Bitto, A | 1 |
| Irrera, N | 1 |
| Pizzino, G | 1 |
| Sangari, D | 1 |
| Cinquegrani, M | 1 |
| Roberts, W | 1 |
| Atteritano, M | 1 |
| Altavilla, D | 1 |
| Squadrito, F | 1 |
| Saitta, A | 1 |
| van Rooij, E | 1 |
| Sutherland, LB | 1 |
| Qi, X | 1 |
| Richardson, JA | 1 |
| Hill, J | 1 |
| Olson, EN | 1 |
| Dussaillant, G | 1 |
| Jalil, JE | 1 |
| Cespedes, C | 1 |
| Robbins, RJ | 1 |
| Swain, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation in Both Skeletal Muscle and Adipose Tissue[NCT01911091] | 56 participants (Anticipated) | Interventional | 2013-07-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for triiodothyronine and Cirrhosis
| Article | Year |
|---|---|
Defective autophagy contributes to endometrial epithelial-mesenchymal transition in intrauterine adhesions.
Topics: Actins; Adenosine; AMP-Activated Protein Kinases; Animals; Autophagy; Cadherins; Cathepsin D; Chloro | 2022 |
Thyroid hormone mediates cardioprotection against postinfarction remodeling and dysfunction through the IGF-1/PI3K/AKT signaling pathway.
Topics: Animals; Apoptosis; Atrial Remodeling; Cardiotonic Agents; Fibrosis; Heart Failure; Male; Mice; Mice | 2021 |
Triiodothyronine ameliorates silica-induced pulmonary inflammation and fibrosis in mice.
Topics: Animals; Fibrosis; Inflammation; Lung; Mice; Mice, Inbred C57BL; Pneumonia; Pulmonary Fibrosis; Sili | 2021 |
Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats.
Topics: Animals; Echocardiography; Exercise Therapy; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardi | 2018 |
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele | 2018 |
Propylthiouracil prevents cutaneous and pulmonary fibrosis in the reactive oxygen species murine model of systemic sclerosis.
Topics: Actins; Animals; Antithyroid Agents; Blotting, Western; Disease Models, Animal; Extracellular Signal | 2013 |
Control of stress-dependent cardiac growth and gene expression by a microRNA.
Topics: Animals; Cardiac Myosins; Cardiomegaly; Fibrosis; Gene Deletion; Gene Expression Regulation; Heart; | 2007 |
Amiodarone protection against myocardial injury and fibrosis induced by isoprenaline is abolished by thyroid hormone.
Topics: Amiodarone; Animals; Fibrosis; Fluorescent Antibody Technique; Heart; Isoproterenol; Male; Myocardiu | 1994 |
C-myc protooncogene modulates cardiac hypertrophic growth in transgenic mice.
Topics: Actins; Adenylyl Cyclases; Animals; Cardiomegaly; Fibrosis; Heart; Isomerism; Isoproterenol; Mice; M | 1992 |