triiodothyronine has been researched along with Choriocarcinoma in 23 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 7.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "We have studied the uptake of 125I-thyroxine (125I-T4) in the human choriocarcinoma cell line JAR." | 7.69 | Uptake of thyroxine in the human choriocarcinoma cell line JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Payne, EJ, 1995) |
| "We compared the specificities of transport mechanisms for uptake and efflux of thyroid hormones in cells of the human choriocarcinoma cell line, JAR, to determine whether triiodothyronine (T3), thyroxine (T4) and reverse T3 (rT3) are carried by the same transport mechanism." | 3.70 | Comparison of mechanisms mediating uptake and efflux of thyroid hormones in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Rowan, KA, 1999) |
| "We investigated transport systems for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR, using a range of structurally similar compounds to determine whether these thyroid hormones are transported by common or different mechanisms." | 3.70 | Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA, 2000) |
| "We have studied the uptake of 125I-thyroxine (125I-T4) in the human choriocarcinoma cell line JAR." | 3.69 | Uptake of thyroxine in the human choriocarcinoma cell line JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH; Payne, EJ, 1995) |
| "We studied the effect of a number of amino acids on uptake of L-triiodothyronine (T3) in the human choriocarcinoma cell line, JAR." | 3.69 | Interactions between transport of triiodothyronine and tryptophan in JAR cells. ( Manley, SW; Mitchell, AM; Mortimer, RH, 1994) |
| "We studied uptake of L-triiodothyronine (T3) by the human choriocarcinoma cell line, JAR." | 3.68 | Membrane transport of thyroid hormone in the human choriocarcinoma cell line, JAR. ( Manley, SW; Mitchell, AM; Mortimer, RH, 1992) |
| "Two patients with testicular cancer and 1 patient with molar pregnancy experienced episodes of frank hyperthyroidism." | 1.27 | Thyrotropic activity of acidic isoelectric variants of human chorionic gonadotropin from trophoblastic tumors. ( Hoermann, R; Mann, K; Schneider, N, 1986) |
| "None of the patients with molar pregnancy was clinically thyrotoxic, though serum thyroxine (T4) was increased in 13 and free T4 concentrations were above normal in four of ten in whom measurements were made." | 1.26 | Thyroid function in molar pregnancy. ( Irie, M; Mizuno, M; Nagataki, S; Sakamoto, S; Shizume, K, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (30.43) | 18.7374 |
| 1990's | 11 (47.83) | 18.2507 |
| 2000's | 4 (17.39) | 29.6817 |
| 2010's | 1 (4.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matsunaga, H | 1 |
| Sasaki, S | 1 |
| Suzuki, S | 1 |
| Matsushita, A | 1 |
| Nakamura, H | 1 |
| Nakamura, HM | 1 |
| Hirahara, N | 1 |
| Kuroda, G | 1 |
| Iwaki, H | 1 |
| Ohba, K | 1 |
| Morita, H | 1 |
| Oki, Y | 1 |
| Suda, T | 1 |
| Chan, S | 1 |
| Kachilele, S | 1 |
| Hobbs, E | 1 |
| Bulmer, JN | 2 |
| Boelaert, K | 1 |
| McCabe, CJ | 2 |
| Driver, PM | 1 |
| Bradwell, AR | 1 |
| Kester, M | 1 |
| Visser, TJ | 1 |
| Franklyn, JA | 2 |
| Kilby, MD | 2 |
| GODDEN, JD | 2 |
| GARNETT, ES | 2 |
| Barber, KJ | 1 |
| Khanim, FL | 1 |
| Whitley, GS | 1 |
| Hsieh, TY | 1 |
| Hsu, KF | 1 |
| Kuo, PL | 1 |
| Huang, SC | 1 |
| Trainer, TD | 1 |
| Howard, PL | 1 |
| Mitchell, AM | 6 |
| Manley, SW | 6 |
| Payne, EJ | 1 |
| Mortimer, RH | 7 |
| Quirin-Stricker, C | 1 |
| Nappey, V | 1 |
| Simoni, P | 1 |
| Toussaint, JL | 1 |
| Schmitt, M | 1 |
| Prasad, PD | 1 |
| Leibach, FH | 1 |
| Mahesh, VB | 1 |
| Ganapathy, V | 1 |
| Nickel, BE | 1 |
| Bock, ME | 1 |
| Nachtigal, MW | 1 |
| Cattini, PA | 1 |
| Kitajima, K | 1 |
| Nagaya, T | 1 |
| Jameson, JL | 2 |
| Li, R | 1 |
| Luciakova, K | 1 |
| Zaid, A | 1 |
| Betina, S | 1 |
| Fridell, E | 1 |
| Nelson, BD | 1 |
| Rowan, KA | 2 |
| Powell, KA | 1 |
| Nagataki, S | 1 |
| Mizuno, M | 1 |
| Sakamoto, S | 1 |
| Irie, M | 1 |
| Shizume, K | 1 |
| Stahl, TJ | 1 |
| Ashizawa, K | 1 |
| Cheng, SY | 1 |
| Chatterjee, VK | 1 |
| Lee, JK | 1 |
| Rentoumis, A | 1 |
| Mann, K | 1 |
| Schneider, N | 1 |
| Hoermann, R | 1 |
| Sommerville, IF | 1 |
| Bagshawe, KD | 1 |
1 review available for triiodothyronine and Choriocarcinoma
| Article | Year |
|---|---|
Thyroid function tests in thyroid and nonthyroid disease.
Topics: Adult; Aged; Autoantibodies; Calcitonin; Choriocarcinoma; Female; Fetus; Hepatitis; Humans; Hyperthy | 1983 |
1 trial available for triiodothyronine and Choriocarcinoma
| Article | Year |
|---|---|
The effect of choriocarcinoma on serum thyroid hormone-binding capacity.
Topics: Adolescent; Adult; Blood Proteins; Choriocarcinoma; Chorionic Gonadotropin; Clinical Trials as Topic | 1967 |
21 other studies available for triiodothyronine and Choriocarcinoma
| Article | Year |
|---|---|
Essential Role of GATA2 in the Negative Regulation of Type 2 Deiodinase Gene by Liganded Thyroid Hormone Receptor β2 in Thyrotroph.
Topics: Animals; Cell Line; Choriocarcinoma; Chromatin Immunoprecipitation; Colforsin; GATA2 Transcription F | 2015 |
Placental iodothyronine deiodinase expression in normal and growth-restricted human pregnancies.
Topics: Adult; Choriocarcinoma; Female; Fetal Growth Retardation; Gene Expression Regulation, Enzymologic; H | 2003 |
THE 131-I-TRIIODOTHYRONINE-RESIN UPTAKE TEST.
Topics: Acidosis; Antithyroid Agents; Basal Metabolism; Choriocarcinoma; Erythrocytes; Hypercholesterolemia; | 1964 |
The in vitro effects of triiodothyronine on epidermal growth factor-induced trophoblast function.
Topics: Cell Division; Cell Line, Transformed; Cell Movement; Choriocarcinoma; Epidermal Growth Factor; Fema | 2005 |
Uterine choriocarcinoma accompanied by an extremely high human chorionic gonadotropin level and thyrotoxicosis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Choriocarcinoma; Chorionic Gonadotropin; Cycl | 2008 |
Uptake of thyroxine in the human choriocarcinoma cell line JAR.
Topics: Choriocarcinoma; Female; Humans; Kinetics; Ouabain; Temperature; Thyroxine; Time Factors; Triiodothy | 1995 |
Trans-activation by thyroid hormone receptors of the 5' flanking region of the human ChAT gene.
Topics: Amino Acid Sequence; Animals; Base Sequence; Breast Neoplasms; Cells, Cultured; Chlorocebus aethiops | 1994 |
Relationship between thyroid hormone transport and neutral amino acid transport in JAR human choriocarcinoma cells.
Topics: Amino Acids; Biological Transport; Cell Line; Choline; Choriocarcinoma; Female; Humans; Hydrogen-Ion | 1994 |
Differential expression of human placental growth hormone variant and chorionic somatomammotropin genes in choriocarcinoma cells treated with methotrexate.
Topics: Actins; Base Sequence; Choriocarcinoma; Chorionic Gonadotropin; DNA Probes; Female; Gene Expression; | 1993 |
Dominant negative and DNA-binding properties of mutant thyroid hormone receptors that are defective in homodimerization but not heterodimerization.
Topics: Base Sequence; Cell Line; Choriocarcinoma; DNA; Glycoprotein Hormones, alpha Subunit; Humans; Lucife | 1995 |
Thyroid hormone activates transcription from the promoter regions of some human nuclear-encoded genes of the oxidative phosphorylation system.
Topics: Animals; Cell Nucleus; Choriocarcinoma; Cytochromes c1; Female; Genes, Reporter; Humans; Liver; Mito | 1997 |
Interactions between transport of triiodothyronine and tryptophan in JAR cells.
Topics: Biological Transport; Choriocarcinoma; Female; Humans; Pregnancy; Triiodothyronine; Tryptophan; Tumo | 1994 |
Uptake of reverse T3 in the human choriocarcinoma cell line, JAr.
Topics: Choriocarcinoma; Female; Humans; Iodine Radioisotopes; Kinetics; Pregnancy; Thyroxine; Triiodothyron | 1999 |
Comparison of mechanisms mediating uptake and efflux of thyroid hormones in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Biological Transport, Active; Choriocarcinoma; Female; H | 1999 |
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenas | 2000 |
Thyroid function in molar pregnancy.
Topics: Adult; Body Weight; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; Hype | 1977 |
Radioimmunoassay and the hormones of thyroid function.
Topics: Acromegaly; Adenoma, Chromophobe; Blood; Calcitonin; Choriocarcinoma; Female; Glucocorticoids; Goite | 1975 |
Regulation of thyroid hormone receptor-mediated transcription by a cytosol protein.
Topics: Animals; Carrier Proteins; Cell Line; Chloramphenicol O-Acetyltransferase; Choriocarcinoma; Cytosol; | 1992 |
Membrane transport of thyroid hormone in the human choriocarcinoma cell line, JAR.
Topics: Biological Transport; Cell Membrane; Choriocarcinoma; Female; Humans; Kinetics; Maternal-Fetal Excha | 1992 |
Negative regulation of the thyroid-stimulating hormone alpha gene by thyroid hormone: receptor interaction adjacent to the TATA box.
Topics: Base Sequence; Cell Line; Cell Nucleus; Choriocarcinoma; Chromosome Deletion; Female; Gene Expressio | 1989 |
Thyrotropic activity of acidic isoelectric variants of human chorionic gonadotropin from trophoblastic tumors.
Topics: Adult; Animals; Blood; Choriocarcinoma; Chorionic Gonadotropin; Female; Humans; Hydatidiform Mole; I | 1986 |