Page last updated: 2024-11-08

triiodothyronine and Central Nervous System Disease

triiodothyronine has been researched along with Central Nervous System Disease in 4 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
" 3,5-diiodothyronine (T2) has been used with success in rat models of dyslipidemia and NAFLD, but the outcome of a clinical trial with a synthetic T2 analogue was disappointing."5.05Thyroid Hormone Analogues: An Update. ( Zucchi, R, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Zucchi, R1
Nomura, R1
Miyai, K1
Kuge, R1
Okura, T1
Goto, M1
Hasegawa, Y1
Solá, E1
Gómez-Balaguer, M1
Morillas, C1
Garzón, S1
García, S1
Morcillo, EJ1
Hernández-Mijares, A1
Himwich, HE1

Reviews

1 review available for triiodothyronine and Central Nervous System Disease

ArticleYear
Thyroid Hormone Analogues: An Update.
    Thyroid : official journal of the American Thyroid Association, 2020, Volume: 30, Issue:8

    Topics: Acetates; Anilides; Animals; Central Nervous System Diseases; Clinical Trials as Topic; Diiodothyron

2020

Other Studies

3 other studies available for triiodothyronine and Central Nervous System Disease

ArticleYear
Free T3 to free T4 ratio less than 2.0 suggests low T3 syndrome rather than central hypothyroidism from the age of two to eighteen years.
    Endocrine journal, 2017, Feb-27, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Age Factors; Central Nervous System Diseases; Child; Child, Preschool; Diagnosis,

2017
Massive triiodothyronine intoxication: efficacy of hemoperfusion?
    Thyroid : official journal of the American Thyroid Association, 2002, Volume: 12, Issue:7

    Topics: Adult; Cardiovascular Diseases; Central Nervous System Diseases; Critical Care; Female; Hemoperfusio

2002
Summary of symposium.
    Biological psychiatry, 1975, Volume: 10, Issue:4

    Topics: Antipsychotic Agents; Autistic Disorder; Brain; Bufotenin; Central Nervous System Diseases; Electroe

1975