triiodothyronine has been researched along with Cardiomegaly in 97 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Type 2 Angiotensin II receptors (AT2R) are shown to be upregulated in cardiac hypertrophy observed in hyperthyroidism and this receptor has been reported to mediate cardioprotection against ischemic injury." | 7.79 | Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion. ( Barreto-Chaves, ML; da Silva, IB; Gomes, DA; Tavares, FM, 2013) |
| " Cardiac hypertrophy, structural remodeling, and expression of the genes associated with fatty acid metabolism were examined in rats treated with triiodothyronine (T3) alone (8 μg/100 g body weight (BW), i." | 3.79 | Hyperthyroidism causes cardiac dysfunction by mitochondrial impairment and energy depletion. ( Bandyopadhyay, A; Chander, V; De, K; Kar, D; Maity, S, 2013) |
| " Type 2 Angiotensin II receptors (AT2R) are shown to be upregulated in cardiac hypertrophy observed in hyperthyroidism and this receptor has been reported to mediate cardioprotection against ischemic injury." | 3.79 | Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion. ( Barreto-Chaves, ML; da Silva, IB; Gomes, DA; Tavares, FM, 2013) |
| " Hyperthyroidism, with attendant cardiac hypertrophy, was induced by the injection of L-thyroxine (200 microg/kg body wt) daily for 7 days." | 3.70 | Thyroid hormone-induced overexpression of functional ryanodine receptors in the rabbit heart. ( Jiang, M; Narayanan, N; Tokmakejian, S; Xu, A, 2000) |
| "Hyperthyroidism was induced in dogs by subcutaneous injection of triiodothyronine (T3; 1 mg." | 3.68 | Cardiac angiotensin receptors in experimental hyperthyroidism in dogs. ( Brown, L; Hoey, A; Marchant, C; Sernia, C, 1993) |
| "We examined changes in the expression of fibronectin during the induction of cardiac hypertrophy by L-triiodothyronine administration and by mineralocorticoid- and salt-induced experimental hypertension." | 3.68 | Fibronectin expression in the normal and hypertrophic rat heart. ( Brecher, P; Mamuya, WS, 1992) |
| "Three models of cardiac hypertrophy (aortic constriction, application of isoproterenol, daily injections of triiodothyronine) were characterized in haemodynamic and in metabolic terms." | 3.67 | Correlation between haemodynamic and metabolic changes in three models of experimental cardiac hypertrophy. ( Zimmer, HG, 1984) |
| "Cardiac hypertrophy, induced in rats by either tri-iodothyronine or isoproterenol, administered daily for 7 days, was monitored using several parameters." | 3.66 | Protein synthesis in the early stages of cardiac hypertrophy. ( Clarke, K; Ward, LC, 1983) |
| "The main biochemical features of protein synthesis in the myocardium are described as well as several metabolic alterations that occur during the very early stages in three models of cardiac hypertrophy resulting from pressure overload in vivo and in vitro, application of a high dose of isoprenaline and repeated daily administration of triiodothyronine." | 3.66 | Early metabolic alterations during the development of experimentally induced cardiac hypertrophy. ( Gerlach, E; Zimmer, HG, 1980) |
| "As a part of a continuing study on the effects of thyroid hormones on heart muscle, triiodothyroacetic acid (triac), either alone or concurrently with propranolol, has been administered to rats during pregnancy." | 3.66 | Production of cardiac muscle abnormalities in offspring of rats receiving triiodothyroacetic acid (triac) and the effect of beta adrenergic blockade. ( Hawkey, CM; Olsen, EG; Symons, C, 1981) |
| "Considering that cardiac hypertrophy is commonly associated to hyperthyroidism condition, the present study aimed to investigate the contribution of UPS in cardiac hypertrophy induced by thyroid hormones." | 1.51 | Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidism. ( Barreto-Chaves, ML; Demasi, M; Lino, CA, 2019) |
| "Hyperthyroidism was confirmed by evaluation of T3 and T4 levels, as well as cardiac hypertrophy development." | 1.48 | Decreased PGC1- α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism. ( Araujo, ASDR; Barboza, TE; Bello-Klein, A; Bonetto, JHP; Carraro, CC; DE Araujo, CC; DE Castro, AL; DE Lima-Seolin, BG; Singal, PK; Siqueira, R; Teixeira, RB, 2018) |
| "NF-қB contributes to T3-induced cardiac hypertrophy in vitro and in vivo." | 1.46 | S100A8/MYD88/NF-қB: a novel pathway involved in cardiomyocyte hypertrophy driven by thyroid hormone. ( Barreto-Chaves, MLM; Gupta, S; Moriscot, AS; Munhoz, CD; Takano, APC, 2017) |
| "T3-induced cardiac hypertrophy was not observed in TRβΔ337T mice, showing the fundamental role of THRβ in cardiac hypertrophy." | 1.42 | The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice. ( do Império, GE; dos Santos Almeida, NA; Fuziwara, CS; Kimura, ET; Olivares, EL; Ortiga-Carvalho, TM; Pazos-Moura, CC; Pereira, GF; Ramos, IP; Santiago, LA, 2015) |
| "Cardiac hypertrophy was observed in Hyper pups on GD20." | 1.40 | Maternal hyperthyroidism alters the pattern of expression of cardiac renin-angiotensin system components in rat offspring. ( Barreto-Chaves, ML; Lino, CA; Shibata, CE, 2014) |
| "Hyperthyroidism has been shown to induce cardiac hypertrophy, which is a contributing factor to heart failure." | 1.38 | The protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy. ( Guo, T; Hou, D; Jiang, X; Liu, Y; Lu, Z; Wang, D; Xu, W; Yu, B; Zen, K; Zhang, CY, 2012) |
| "Myxedema coma (MC) is a rare, but often fatal endocrine emergency." | 1.37 | A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis. ( Chihara, K; Hino, Y; Iida, K; Ohara, T, 2011) |
| "Pressure overload-induced cardiac hypertrophy results in a pathological type of hypertrophy with activation of signaling cascades like the extracellular signal-regulated kinase (ERK) pathway, which promotes negative cardiac remodeling and decreased contractile function." | 1.36 | Thyroid hormone inhibits ERK phosphorylation in pressure overload-induced hypertrophied mouse hearts through a receptor-mediated mechanism. ( Chavira, CV; Dillmann, WH; Scott, BT; Suarez, J; Suarez-Ramirez, JA, 2010) |
| "Cardiac hypertrophy was evident in AMI hearts after 13 weeks but not at 2 weeks." | 1.34 | Time-dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling. ( Cokkinos, DV; Dimopoulos, A; Kokkinos, AD; Kostopanagiotou, G; Markakis, K; Mourouzis, I; Panagiotou, M; Pantos, C; Saranteas, T; Xinaris, C, 2007) |
| "In various models of cardiac hypertrophy, e." | 1.32 | The expression of mRNA of cytokines and of extracellular matrix proteins in triiodothyronine-treated rat hearts. ( Baba, HA; Briest, W; Rassler, B; Ziegelhöffer-Mihalovicová, B; Zimmer, HG, 2003) |
| "Physiological and pathological cardiac hypertrophy have directionally opposite changes in transcription of thyroid hormone (TH)-responsive genes, including alpha- and beta-myosin heavy chain (MyHC) and sarcoplasmic reticulum Ca(2+)-ATPase (SERCA), and TH treatment can reverse molecular and functional abnormalities in pathological hypertrophy, such as pressure overload." | 1.31 | Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. ( Aoyagi, T; Baxter, JD; Bristow, MR; Camacho, SA; Eto, Y; Kinugawa, K; Long, CS; Ribeiro, RC; Simpson, PC; Yonekura, K, 2001) |
| "Hyperthyroidism was induced by daily intraperitoneal injection of thyroxine (T4) (600 microg/kg) with or without cilazapril (10 mg/kg per day, orally), and control rats were given by vehicle." | 1.31 | Cilazapril prevents cardiac hypertrophy and postischemic myocardial dysfunction in hyperthyroid rats. ( Asahi, T; Oshiro, Y; Shimabukuro, M; Takasu, N; Yoshida, H, 2001) |
| "Iso induced cardiac hypertrophy." | 1.30 | Effects of thyroid status on expression of voltage-gated potassium channels in rat left ventricle. ( Kambe, F; Kamiya, K; Nishiyama, A; Seo, H; Toyama, J, 1998) |
| "Although cardiac hypertrophy is reported to be induced in rats by a fat-free diet, little is known of the consequences of depressed myocardial long-chain fatty acid uptake." | 1.29 | Effect of sulfo-N-succinimidyl palmitate on the rat heart: myocardial long-chain fatty acid uptake and cardiac hypertrophy. ( Kawamura, K; Kusaka, Y; Matsunaga, Y; Miyazaki, H; Okamoto, F; Tanaka, T; Terasaki, F, 1995) |
| "In contrast, T3-induced cardiac hypertrophy was not accompanied by changes in Gi alpha-mRNA expression." | 1.28 | Isoprenaline-induced increase in mRNA levels of inhibitory G-protein alpha-subunits in rat heart. ( Eschenhagen, T; Mende, U; Nose, M; Schmitz, W; Scholz, H; Warnholtz, A; Wüstel, JM, 1991) |
| "The remaining cardiac hypertrophy correlated with the still existing elevation in the pressure-volume performance." | 1.28 | Inotropic response of the rat heart during development and regression of triiodothyronine-induced hypertrophy. ( Lortet, S; Rossi, A; Zimmer, HG, 1989) |
| "Treatment with triiodothyronine significantly, diminished polyADP-ribosylation of three specific groups of polyADP-ribosylated non-histone chromatin proteins corresponding to 130 kDa, 90-80 kDa and 80-65 kDa." | 1.27 | Evidence for the macromolecular basis of regulation of heart hypertrophy. ( Jackowski, G; Kun, E, 1984) |
| " The chronic administration of thyroid hormone also results in cardiac hypertrophy and increased numbers of beta-adrenergic receptors in cardiac membranes." | 1.27 | Regression of thyroid hormone induced cardiac hypertrophy: effect on cardiac beta receptors and adenyl cyclase activity. ( Atkins, FL; Carney, R; Love, S, 1983) |
| "In contrast, cardiac hypertrophy produced by thyroid hormone excess was not associated with induction of the atrial natriuretic factor gene or fetal contractile protein isogenes." | 1.27 | Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. ( Izumo, S; Mahdavi, V; Nadal-Ginard, B, 1988) |
| "Severe cardiac hypertrophy has been produced experimentally in rats by long-term, low-dose treatment with tri-iodothyroacetic acid." | 1.25 | The production of cardiac hypertrophy by tri-iodothyroacetic acid. ( Hawkey, CM; Olsen, EG; Symons, C, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (35.05) | 18.7374 |
| 1990's | 19 (19.59) | 18.2507 |
| 2000's | 23 (23.71) | 29.6817 |
| 2010's | 18 (18.56) | 24.3611 |
| 2020's | 3 (3.09) | 2.80 |
| Authors | Studies |
|---|---|
| Li, GQ | 1 |
| Liu, XM | 1 |
| Liu, BL | 1 |
| Zhong, Y | 1 |
| Gu, QW | 1 |
| Miao, JJ | 1 |
| Wang, J | 1 |
| Liu, S | 1 |
| Mao, XM | 1 |
| Herrmann, B | 1 |
| Harder, L | 1 |
| Oelkrug, R | 1 |
| Chen, J | 1 |
| Gachkar, S | 1 |
| Nock, S | 1 |
| Resch, J | 1 |
| Korkowski, M | 1 |
| Heuer, H | 1 |
| Mittag, J | 1 |
| Lino, CA | 3 |
| de Bortoli Teixeira, L | 1 |
| Capelupe Simões, S | 1 |
| de Oliveira Silva, T | 1 |
| Diniz, GP | 4 |
| da Costa-Neto, CM | 1 |
| Barreto-Chaves, MLM | 3 |
| Senger, N | 1 |
| Melo, MB | 1 |
| Campagnole-Santos, MJ | 1 |
| Santos, RAS | 1 |
| Teixeira, RB | 1 |
| Barboza, TE | 1 |
| DE Araujo, CC | 1 |
| Siqueira, R | 2 |
| DE Castro, AL | 2 |
| Bonetto, JHP | 1 |
| DE Lima-Seolin, BG | 1 |
| Carraro, CC | 1 |
| Bello-Klein, A | 2 |
| Singal, PK | 1 |
| Araujo, ASDR | 1 |
| Demasi, M | 1 |
| Barreto-Chaves, ML | 6 |
| Maity, S | 1 |
| Kar, D | 1 |
| De, K | 2 |
| Chander, V | 1 |
| Bandyopadhyay, A | 2 |
| Takano, AP | 2 |
| Tavares, FM | 1 |
| da Silva, IB | 1 |
| Gomes, DA | 1 |
| Rozanski, A | 1 |
| Kato, PN | 1 |
| Soares, AG | 1 |
| Lellis-Santos, C | 1 |
| Campos, JC | 1 |
| Ferreira, JC | 1 |
| Moriscot, AS | 2 |
| Tavares, AV | 1 |
| Campos, C | 1 |
| Fernandes, RO | 1 |
| Conzatti, A | 1 |
| Bicca, AM | 1 |
| Fernandes, TR | 1 |
| Sartório, CL | 1 |
| Schenkel, PC | 1 |
| da Rosa Araujo, AS | 1 |
| do Império, GE | 1 |
| Ramos, IP | 1 |
| Santiago, LA | 1 |
| Pereira, GF | 1 |
| dos Santos Almeida, NA | 1 |
| Fuziwara, CS | 1 |
| Pazos-Moura, CC | 1 |
| Kimura, ET | 1 |
| Olivares, EL | 1 |
| Ortiga-Carvalho, TM | 1 |
| Wadosky, KM | 1 |
| Berthiaume, JM | 1 |
| Tang, W | 1 |
| Zungu, M | 1 |
| Portman, MA | 1 |
| Gerdes, AM | 1 |
| Willis, MS | 1 |
| Takano, APC | 1 |
| Munhoz, CD | 1 |
| Gupta, S | 1 |
| Makino, A | 1 |
| Suarez, J | 2 |
| Wang, H | 1 |
| Belke, DD | 1 |
| Scott, BT | 2 |
| Dillmann, WH | 2 |
| Roepke, TK | 1 |
| King, EC | 1 |
| Reyna-Neyra, A | 1 |
| Paroder, M | 1 |
| Purtell, K | 1 |
| Koba, W | 1 |
| Fine, E | 1 |
| Lerner, DJ | 1 |
| Carrasco, N | 1 |
| Abbott, GW | 1 |
| Xie, MJ | 1 |
| Chang, H | 1 |
| Wang, YY | 1 |
| Zhang, L | 1 |
| Song, Z | 1 |
| Guo, WG | 1 |
| Wang, T | 1 |
| Che, HL | 1 |
| Yu, ZB | 1 |
| Davis, PJ | 1 |
| Davis, FB | 1 |
| Lin, HY | 1 |
| Suarez-Ramirez, JA | 1 |
| Chavira, CV | 1 |
| Iida, K | 1 |
| Hino, Y | 1 |
| Ohara, T | 1 |
| Chihara, K | 1 |
| Xu, W | 1 |
| Hou, D | 1 |
| Jiang, X | 1 |
| Lu, Z | 1 |
| Guo, T | 1 |
| Liu, Y | 1 |
| Wang, D | 1 |
| Zen, K | 1 |
| Yu, B | 1 |
| Zhang, CY | 1 |
| Mezősi, E | 1 |
| Bajnok, L | 1 |
| Tóth, K | 1 |
| Shibata, CE | 1 |
| Degens, H | 1 |
| Gilde, AJ | 1 |
| Lindhout, M | 1 |
| Willemsen, PH | 2 |
| Van Der Vusse, GJ | 2 |
| Van Bilsen, M | 2 |
| Liang, F | 1 |
| Webb, P | 1 |
| Marimuthu, A | 1 |
| Zhang, S | 1 |
| Gardner, DG | 1 |
| Ziegelhöffer-Mihalovicová, B | 1 |
| Briest, W | 1 |
| Baba, HA | 1 |
| Rassler, B | 1 |
| Zimmer, HG | 9 |
| GEMMILL, CL | 1 |
| SIMPSON, GM | 1 |
| CRANSWICK, EH | 1 |
| BLAIR, JH | 1 |
| Shohet, RV | 1 |
| Kisanuki, YY | 1 |
| Zhao, XS | 1 |
| Siddiquee, Z | 1 |
| Franco, F | 1 |
| Yanagisawa, M | 1 |
| Okada, S | 1 |
| Saito, T | 1 |
| Yamada, E | 1 |
| Mori, M | 1 |
| Ghosh, G | 1 |
| Datta, M | 1 |
| Konar, A | 1 |
| Bandyopadhyay, J | 1 |
| Bandyopadhyay, D | 1 |
| Bhattacharya, S | 1 |
| Ralphe, JC | 1 |
| Bedell, K | 1 |
| Segar, JL | 1 |
| Scholz, TD | 1 |
| Ledda-Columbano, GM | 1 |
| Molotzu, F | 1 |
| Pibiri, M | 1 |
| Cossu, C | 1 |
| Perra, A | 1 |
| Columbano, A | 1 |
| Pantos, C | 4 |
| Malliopoulou, V | 1 |
| Mourouzis, I | 3 |
| Thempeyioti, A | 1 |
| Paizis, I | 1 |
| Dimopoulos, A | 3 |
| Saranteas, T | 2 |
| Xinaris, C | 3 |
| Cokkinos, DV | 4 |
| Carneiro-Ramos, MS | 1 |
| Minatoya, Y | 1 |
| Ito, K | 1 |
| Kagaya, Y | 1 |
| Asaumi, Y | 1 |
| Takeda, M | 1 |
| Nakayama, M | 1 |
| Takahashi, J | 1 |
| Iguchi, A | 1 |
| Shirato, K | 1 |
| Shimokawa, H | 1 |
| van Rooij, E | 1 |
| Sutherland, LB | 1 |
| Qi, X | 1 |
| Richardson, JA | 1 |
| Hill, J | 1 |
| Olson, EN | 1 |
| Kokkinos, AD | 2 |
| Markakis, K | 2 |
| Panagiotou, M | 2 |
| Kostopanagiotou, G | 1 |
| Zähringer, J | 1 |
| Klaubert, A | 1 |
| Pritzl, N | 1 |
| Stangl, E | 1 |
| Kreuzer, E | 1 |
| Jackowski, G | 2 |
| Kun, E | 2 |
| Gerlach, E | 3 |
| Raymondjean, M | 4 |
| Kneip, B | 4 |
| Kruh, J | 1 |
| Clarke, K | 1 |
| Ward, LC | 1 |
| Petkov, O | 1 |
| Bogdanovsky-Sequeval, D | 1 |
| Bachner, L | 3 |
| Schapira, G | 2 |
| Atkins, FL | 1 |
| Carney, R | 1 |
| Love, S | 1 |
| Wildenthal, K | 1 |
| Sanford, CF | 1 |
| Griffin, EE | 1 |
| Crie, JS | 1 |
| Bartolome, J | 1 |
| Huguenard, J | 1 |
| Slotkin, TA | 1 |
| Hawkey, CM | 2 |
| Olsen, EG | 3 |
| Symons, C | 3 |
| Heron, MI | 1 |
| Rakusan, K | 2 |
| Fazio, S | 2 |
| Biondi, B | 2 |
| Carella, C | 2 |
| Sabatini, D | 1 |
| Cittadini, A | 2 |
| Panza, N | 1 |
| Lombardi, G | 2 |
| Saccà, L | 2 |
| Williams, S | 1 |
| Mesaeli, N | 1 |
| Panagia, V | 1 |
| Fregly, MJ | 1 |
| Rossi, F | 1 |
| Cade, JR | 1 |
| Amato, G | 1 |
| Lupoli, G | 1 |
| Bellastella, A | 1 |
| Green, NK | 1 |
| Gammage, MD | 1 |
| Franklyn, JA | 1 |
| Heagerty, AM | 1 |
| Sheppard, MC | 1 |
| Heckmann, M | 2 |
| Lortet, S | 4 |
| Sernia, C | 1 |
| Marchant, C | 1 |
| Brown, L | 1 |
| Hoey, A | 1 |
| Kusaka, Y | 1 |
| Tanaka, T | 1 |
| Okamoto, F | 1 |
| Terasaki, F | 1 |
| Matsunaga, Y | 1 |
| Miyazaki, H | 1 |
| Kawamura, K | 1 |
| Ray, A | 2 |
| Rossi, A | 3 |
| Aussedat, J | 2 |
| Grably, S | 1 |
| Guo, W | 1 |
| Kamiya, K | 2 |
| Hojo, M | 1 |
| Kodama, I | 1 |
| Toyama, J | 2 |
| Nishiyama, A | 1 |
| Kambe, F | 1 |
| Seo, H | 1 |
| Van Der Lee, KA | 1 |
| Jiang, M | 1 |
| Xu, A | 1 |
| Tokmakejian, S | 1 |
| Narayanan, N | 1 |
| Bell, D | 1 |
| McDermott, BJ | 1 |
| Pantos, CI | 1 |
| Malliopoulou, VA | 1 |
| Mourouzis, IS | 1 |
| Karamanoli, EP | 1 |
| Tzeis, SM | 1 |
| Carageorgiou, HC | 1 |
| Varonos, DD | 1 |
| Kinugawa, K | 1 |
| Yonekura, K | 1 |
| Ribeiro, RC | 1 |
| Eto, Y | 1 |
| Aoyagi, T | 1 |
| Baxter, JD | 1 |
| Camacho, SA | 1 |
| Bristow, MR | 1 |
| Long, CS | 1 |
| Simpson, PC | 1 |
| Asahi, T | 1 |
| Shimabukuro, M | 1 |
| Oshiro, Y | 1 |
| Yoshida, H | 1 |
| Takasu, N | 1 |
| Hawkey, C | 1 |
| Steinkopff, G | 1 |
| Vasdev, SC | 1 |
| Korecky, B | 2 |
| Rastogi, RB | 1 |
| Singhal, RL | 1 |
| Kako, KJ | 1 |
| Bogdanovsky, D | 2 |
| Shapira, G | 1 |
| Newcomb, M | 1 |
| Gibson, K | 1 |
| Harris, P | 1 |
| Robbins, RJ | 1 |
| Swain, JL | 1 |
| Heckman, M | 1 |
| Vincent, M | 1 |
| Sassart, J | 1 |
| Mamuya, WS | 1 |
| Brecher, P | 1 |
| Campbell, SE | 1 |
| Eschenhagen, T | 1 |
| Mende, U | 1 |
| Nose, M | 1 |
| Schmitz, W | 1 |
| Scholz, H | 1 |
| Warnholtz, A | 1 |
| Wüstel, JM | 1 |
| Adler, K | 1 |
| Boels, P | 1 |
| Ganten, U | 1 |
| Ganten, D | 1 |
| Morano, I | 1 |
| Christe, ME | 1 |
| Rodgers, RL | 2 |
| McNeill, JH | 1 |
| Izumo, S | 2 |
| Lompré, AM | 1 |
| Matsuoka, R | 1 |
| Koren, G | 1 |
| Schwartz, K | 1 |
| Nadal-Ginard, B | 2 |
| Mahdavi, V | 2 |
| Shibata, T | 1 |
| Hunter, WC | 1 |
| Sagawa, K | 1 |
| Koga, H | 1 |
| Kaku, T | 1 |
| Hashiba, K | 1 |
| Rupp, H | 1 |
| Elimban, V | 1 |
| Dhalla, NS | 1 |
| Friberg, P | 1 |
| Harden, RM | 1 |
| Alexander, WD | 1 |
| Papadopoulos, S | 1 |
| Harrison, MT | 1 |
| Macfarlane, S | 1 |
| Van Liere, EJ | 1 |
| Sizemore, DA | 1 |
| Hunnell, J | 1 |
| Mowery, MB | 1 |
| Lindsay, HA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation in Both Skeletal Muscle and Adipose Tissue[NCT01911091] | 56 participants (Anticipated) | Interventional | 2013-07-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for triiodothyronine and Cardiomegaly
| Article | Year |
|---|---|
[The heart as an endocrine organ].
Topics: Adipocytes; Adipokines; Aldosterone; Biomarkers; Cardiomegaly; Coronary Artery Disease; Cytokines; H | 2012 |
[Hypertension associated with hyperthyroidism and hypothyroidism].
Topics: Animals; Atrial Natriuretic Factor; Blood Volume; Cardiomegaly; Catecholamines; Humans; Hypertension | 2004 |
1 trial available for triiodothyronine and Cardiomegaly
| Article | Year |
|---|---|
Diastolic dysfunction in patients on thyroid-stimulating hormone suppressive therapy with levothyroxine: beneficial effect of beta-blockade.
Topics: Adult; Bisoprolol; Cardiomegaly; Diastole; Echocardiography, Doppler; Female; Goiter; Heart Rate; He | 1995 |
94 other studies available for triiodothyronine and Cardiomegaly
| Article | Year |
|---|---|
High triiodothyronine levels induce myocardial hypertrophy via BAFF overexpression.
Topics: Animals; B-Cell Activating Factor; Cardiomegaly; Female; Hyperthyroidism; Mice; Mice, Inbred C57BL; | 2022 |
Central Hypothyroidism Impairs Heart Rate Stability and Prevents Thyroid Hormone-Induced Cardiac Hypertrophy and Pyrexia.
Topics: Animals; Cardiomegaly; Crosses, Genetic; Enzyme-Linked Immunosorbent Assay; Fever; Gene Expression P | 2020 |
Beta-arrestin 2 mediates cardiac hypertrophy induced by thyroid hormones via AT1R.
Topics: Animals; Animals, Newborn; beta-Arrestin 2; Cardiomegaly; Cells, Cultured; Endocytosis; Enzyme Activ | 2021 |
Angiotensin-(1-7) reduces cardiac effects of thyroid hormone by GSK3Β/NFATc3 signaling pathway.
Topics: Angiotensin I; Animals; Cardiomegaly; Cells, Cultured; Echocardiography; Glycogen Synthase Kinase 3 | 2018 |
Decreased PGC1- α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Body Weight; Cardiomegaly; Gene Expression Regulatio | 2018 |
Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidism.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Hyperthyroidism; Male; My | 2019 |
Hyperthyroidism causes cardiac dysfunction by mitochondrial impairment and energy depletion.
Topics: Adenosine Triphosphate; Animals; Bezafibrate; Cardiomegaly; Disease Models, Animal; Down-Regulation; | 2013 |
AMPK signaling pathway is rapidly activated by T3 and regulates the cardiomyocyte growth.
Topics: AMP-Activated Protein Kinases; Animals; Animals, Newborn; Cardiomegaly; Enzyme Activation; Gene Expr | 2013 |
Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion.
Topics: AMP-Activated Protein Kinases; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blocker | 2013 |
M-protein is down-regulated in cardiac hypertrophy driven by thyroid hormone in rats.
Topics: Animals; Animals, Newborn; Base Sequence; Cardiomegaly; Cell Line; Cells, Cultured; Connectin; Down- | 2013 |
Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Catalase; Disease Models, Animal; Glutathione Disulfide; | 2014 |
The Impact of a Non-Functional Thyroid Receptor Beta upon Triiodotironine-Induced Cardiac Hypertrophy in Mice.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Humans; Hyperthyroidism; | 2015 |
MuRF1 mono-ubiquitinates TRα to inhibit T3-induced cardiac hypertrophy in vivo.
Topics: Animals; Biopsy; Cardiomegaly; Cell Line; Echocardiography; Mice; Mice, Knockout; Muscle Proteins; M | 2016 |
S100A8/MYD88/NF-қB: a novel pathway involved in cardiomyocyte hypertrophy driven by thyroid hormone.
Topics: Animals; Atrial Natriuretic Factor; Calgranulin A; Cardiomegaly; Cells, Cultured; Male; Mice, Inbred | 2017 |
Thyroid hormone receptor-beta is associated with coronary angiogenesis during pathological cardiac hypertrophy.
Topics: Animals; Blotting, Western; Cardiomegaly; Coronary Vessels; Endothelial Cells; Heart Ventricles; Mal | 2009 |
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis.
Topics: Animals; Arrhythmias, Cardiac; Cardiomegaly; Crosses, Genetic; Heterozygote; Homozygote; Hypothyroid | 2009 |
Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ.
Topics: Acetophenones; Angiotensin II; Animals; Apoptosis; Benzopyrans; Cardiomegaly; Caspase 3; Caspase 9; | 2010 |
Roles and controls of mTOR in the heart. Focus on "mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy".
Topics: Animals; Cardiomegaly; Heart; Myocarditis; Myocytes, Cardiac; Rats; Resveratrol; Stilbenes; TOR Seri | 2010 |
Thyroid hormone inhibits ERK phosphorylation in pressure overload-induced hypertrophied mouse hearts through a receptor-mediated mechanism.
Topics: Animals; Blood Pressure; Cardiomegaly; Extracellular Signal-Regulated MAP Kinases; Hyperthyroidism; | 2010 |
A case of myxedema coma caused by isolated thyrotropin stimulating hormone deficiency and Hashimoto's thyroiditis.
Topics: Autoantibodies; Carcinoembryonic Antigen; Cardiomegaly; Coma; Female; Hashimoto Disease; Human Growt | 2011 |
The protective role of peroxisome proliferator-activated receptor γ coactivator-1α in hyperthyroid cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cells, Cultured; Gene Expression; Hyperthyroidism; Myocytes, Cardiac; Oxygen | 2012 |
Maternal hyperthyroidism alters the pattern of expression of cardiac renin-angiotensin system components in rat offspring.
Topics: Animals; Animals, Newborn; Cardiomegaly; Female; Fetal Development; Hyperthyroidism; Mothers; Myocar | 2014 |
Functional and metabolic adaptation of the heart to prolonged thyroid hormone treatment.
Topics: Adaptation, Physiological; Animals; Biomarkers; Cardiomegaly; Echocardiography; Heart; Male; Myocard | 2003 |
Triiodothyronine increases brain natriuretic peptide (BNP) gene transcription and amplifies endothelin-dependent BNP gene transcription and hypertrophy in neonatal rat ventricular myocytes.
Topics: Animals; Animals, Newborn; Cardiomegaly; Drug Synergism; Endothelins; Heart Ventricles; Myocytes, Ca | 2003 |
The expression of mRNA of cytokines and of extracellular matrix proteins in triiodothyronine-treated rat hearts.
Topics: Animals; Body Weight; Cardiomegaly; Carrier Proteins; Cytokines; Extracellular Matrix Proteins; Fema | 2003 |
Cardiac hypertrophy in rats and mice given 3, 3', 5-triiodo-L-thyronine orally.
Topics: Animals; Cardiomegaly; Mice; Rats; Thyronines; Triiodothyronine | 1958 |
THYROID INDICES IN CHRONIC SCHIZOPHRENIA. II.
Topics: Behavior; Cardiomegaly; Cerebrospinal Fluid Proteins; Cholesterol; Hemoglobins; Humans; Iodine Isoto | 1964 |
Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy.
Topics: Aging; Alleles; Animals; Cardiomegaly; Endothelin-1; Female; Gene Deletion; Genetic Predisposition t | 2004 |
Analysis of differentially expressed genes in hyperthyroid-induced hypertrophied heart by cDNA microarray.
Topics: Animals; Biological Transport; Cardiomegaly; Cells, Cultured; DNA, Complementary; Gene Expression; G | 2004 |
Correlation between myocardial malate/aspartate shuttle activity and EAAT1 protein expression in hyper- and hypothyroidism.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; Cardiomegaly; Excitatory Amino Acid Transp | 2005 |
Thyroid hormone induces cyclin D1 nuclear translocation and DNA synthesis in adult rat cardiomyocytes.
Topics: Animals; Bromodeoxyuridine; Cardiomegaly; Cell Cycle; Cell Nucleus; Creatine Kinase; Creatinine; Cyc | 2006 |
Hyperthyroid hearts display a phenotype of cardioprotection against ischemic stress: a possible involvement of heat shock protein 70.
Topics: Animals; Cardiomegaly; Cell Survival; Heart; HSP70 Heat-Shock Proteins; Hyperthyroidism; Male; Malon | 2006 |
Angiotensin type 1 (AT1) and type 2 (AT2) receptors mediate the increase in TGF-beta1 in thyroid hormone-induced cardiac hypertrophy.
Topics: Animals; Blood Pressure; Cardiomegaly; Heart Rate; Hyperthyroidism; Hypothyroidism; Myocardium; Orga | 2007 |
Thyroid hormone at physiological doses restores depressed contractile reserve and impaired calcium handling of cardiac myocytes from chronically unloaded hearts.
Topics: Animals; Calcium; Cardiomegaly; Heart Transplantation; Models, Animal; Myocardial Contraction; Myocy | 2007 |
Depressed contractile reserve and impaired calcium handling of cardiac myocytes from chronically unloaded hearts are ameliorated with the administration of physiological treatment dose of T3 in rats.
Topics: Animals; Calcium; Calcium-Binding Proteins; Cardiomegaly; Heart Transplantation; Male; Myocardial Co | 2007 |
Control of stress-dependent cardiac growth and gene expression by a microRNA.
Topics: Animals; Cardiac Myosins; Cardiomegaly; Fibrosis; Gene Deletion; Gene Expression Regulation; Heart; | 2007 |
Time-dependent changes in the expression of thyroid hormone receptor alpha 1 in the myocardium after acute myocardial infarction: possible implications in cardiac remodelling.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Cell Shape; Echocardiography; In Vitro Techniques; Isomet | 2007 |
Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats.
Topics: Administration, Oral; Animals; Calcium-Binding Proteins; Cardiomegaly; Disease Models, Animal; Echoc | 2007 |
Gene expression in cardiac hypertrophy in rat and human heart muscle.
Topics: Animals; Base Sequence; Cardiomegaly; Contractile Proteins; Gene Expression Regulation; Genes; Human | 1984 |
Evidence for the macromolecular basis of regulation of heart hypertrophy.
Topics: Animals; Cardiomegaly; Chromosomal Proteins, Non-Histone; DNA; Male; Myocardium; NAD+ Nucleosidase; | 1984 |
Correlation between haemodynamic and metabolic changes in three models of experimental cardiac hypertrophy.
Topics: Adenine Nucleotides; Animals; Aorta, Abdominal; Blood Pressure; Cardiomegaly; Constriction; Cyclic A | 1984 |
Some metabolic features of the development of experimentally induced cardiac hypertrophy.
Topics: Adenine Nucleotides; Adrenergic beta-Antagonists; Animals; Cardiomegaly; Cyclic AMP; Female; Isoprot | 1982 |
The influence of triiodothyronine on polyadenosine-diphosphoribose polymerase and RNA synthesis in cardiocyte nuclei.
Topics: Animals; Cardiomegaly; Cell Nucleus; Heart; Hypophysectomy; Male; Myocardium; NAD+ Nucleosidase; Pol | 1982 |
Early molecular events in rat heart after administration of triiodothyronine and isoproterenol.
Topics: Animals; Cardiomegaly; Heart; Isoproterenol; Kinetics; Male; Myocardium; Poly A; Polyribosomes; Prot | 1983 |
Protein synthesis in the early stages of cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Female; Isoproterenol; Kinetics; Myocardium; Protein Biosynthesis; Puromycin; | 1983 |
Some functional changes in experimentally induced cardiac overload.
Topics: Aminooxyacetic Acid; Animals; Atropine; Cardiomegaly; Disease Models, Animal; Drug Combinations; Ele | 1983 |
Independent expression of cyclic AMP dependent protein kinases related to cyclic nucleotide systems, during triiodothyronine induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Cyclic AMP; Cyclic GMP; Cytosol; Isoenzymes; Male; Myocardium; Organ Size; Pr | 1980 |
Regression of thyroid hormone induced cardiac hypertrophy: effect on cardiac beta receptors and adenyl cyclase activity.
Topics: Adenylyl Cyclases; Animals; Cardiomegaly; Cell Membrane; Dihydroalprenolol; Isoproterenol; Kinetics; | 1983 |
Effect of thyrotoxicosis and recovery on myocardial protein balance.
Topics: Animals; Cardiomegaly; Hyperthyroidism; Male; Myocardium; Organ Culture Techniques; Protein Biosynth | 1980 |
Role of ornithine decarboxylase in cardiac growth and hypertrophy.
Topics: Animals; Carboxy-Lyases; Cardiomegaly; Eflornithine; Heart; Isoproterenol; Male; Myocardium; Ornithi | 1980 |
Early metabolic alterations during the development of experimentally induced cardiac hypertrophy.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Blood Pressure; Cardiomegaly; Energy Metabolism; Isopr | 1980 |
Production of cardiac muscle abnormalities in offspring of rats receiving triiodothyroacetic acid (triac) and the effect of beta adrenergic blockade.
Topics: Animals; Cardiomegaly; Female; Heart; Microscopy, Electron; Myocardium; Myofibrils; Pregnancy; Propr | 1981 |
Geometry of coronary capillaries in hyperthyroid and hypothyroid rat heart.
Topics: Alkaline Phosphatase; Animals; Capillaries; Cardiomegaly; Coronary Circulation; Dipeptidyl Peptidase | 1994 |
Phospholipase signalling pathways in thyroxine-induced cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Myocardium; Phosphatidylinositols; Phospholipase D; Rats; Rats, Sprague-Dawle | 1995 |
A role for thyroid hormones in cold-induced elevation of blood pressure and cardiac hypertrophy.
Topics: Amitrole; Animals; Blood Pressure; Cardiomegaly; Catecholamines; Cold Temperature; Hypertension; Hyp | 1994 |
Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine.
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Echocardiography; Electrocardiography; El | 1993 |
Regulation of beta myosin heavy chain, c-myc and c-fos proto-oncogenes in thyroid hormone-induced hypertrophy of the rat myocardium.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Female; Gene Expression Regulat | 1993 |
Cardiovascular response to triiodothyronine in Sprague-Dawley and spontaneously hypertensive rats.
Topics: Animals; Cardiac Catheterization; Cardiomegaly; Female; Heart; Hemodynamics; Hypertension; Rats; Rat | 1993 |
Cardiac angiotensin receptors in experimental hyperthyroidism in dogs.
Topics: Animals; Aorta, Thoracic; Binding Sites; Cardiomegaly; Dogs; Heart Rate; Heart Ventricles; Hyperthyr | 1993 |
Effect of sulfo-N-succinimidyl palmitate on the rat heart: myocardial long-chain fatty acid uptake and cardiac hypertrophy.
Topics: Analysis of Variance; Animals; Autoradiography; Biological Transport; Blood Proteins; Body Weight; C | 1995 |
Energy metabolism response to calcium activation in isolated rat hearts during development and regression of T3-induced hypertrophy.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cardiomegaly; Creatine; Energy Meta | 1995 |
Regulation of Kv4.2 and Kv1.4 K+ channel expression by myocardial hypertrophic factors in cultured newborn rat ventricular cells.
Topics: Adrenergic alpha-Agonists; Amino Acid Sequence; Animals; Animals, Newborn; Cardiomegaly; Cells, Cult | 1998 |
Effects of thyroid status on expression of voltage-gated potassium channels in rat left ventricle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Sequence; Animals; Autoradiography | 1998 |
Effects of fatty acids on uncoupling protein-2 expression in the rat heart.
Topics: Aging; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Diabetes Mellitus, Experimental; Em | 2000 |
Thyroid hormone-induced overexpression of functional ryanodine receptors in the rabbit heart.
Topics: Animals; Binding, Competitive; Body Weight; Calcium; Calcium Channel Blockers; Cardiomegaly; Heart; | 2000 |
Contribution of de novo protein synthesis to the hypertrophic effect of IGF-1 but not of thyroid hormones in adult ventricular cardiomyocytes.
Topics: Animals; Cardiomegaly; Cells, Cultured; DNA; DNA Replication; Heart Ventricles; Insulin-Like Growth | 2000 |
Long-term thyroxine administration increases heat stress protein-70 mRNA expression and attenuates p38 MAP kinase activity in response to ischaemia.
Topics: Animals; Cardiomegaly; Chronic Disease; Electrophoresis, Polyacrylamide Gel; HSP70 Heat-Shock Protei | 2001 |
Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy.
Topics: Animals; Calcium-Transporting ATPases; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene E | 2001 |
Cilazapril prevents cardiac hypertrophy and postischemic myocardial dysfunction in hyperthyroid rats.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Cell S | 2001 |
Effect of triac on the developing heart.
Topics: Animals; Animals, Newborn; Cardiomegaly; Colonic Neoplasms; Ethanolamines; Female; Fetus; Heart; Inj | 1977 |
The production of cardiac hypertrophy by tri-iodothyroacetic acid.
Topics: Acetates; Acid Phosphatase; Alkaline Phosphatase; Animals; Cardiomegaly; Disease Models, Animal; Gly | 1975 |
Effect of triiodothyronine on the biosynthesis of adenine nucleotides and proteins in the rat heart.
Topics: Adenine; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate | 1977 |
Myocardial lipid metabolism in cardiac hyper- and hypo-function. Studies on triiodothyronine-treated and transplanted rat hearts.
Topics: Animals; Atrophy; Cardiomegaly; Cholesterol; Fatty Acids; Glycerides; Heart Transplantation; Hyperth | 1977 |
Increase of protein synthesis in cell-free system prepared from hypertrophied rat heart during L-triiodothyronine treatment.
Topics: Animals; Cardiomegaly; Cell-Free System; Kinetics; Male; Muscle Proteins; Protein Biosynthesis; Rats | 1977 |
An improved and easy technique for polyamine determination in biological samples. Application to cell-free system from hypertrophied rat heart.
Topics: Animals; Cardiomegaly; Chromatography, Ion Exchange; Heart; Kinetics; Myocardium; Peptide Initiation | 1979 |
Effect of 3,5,3'-triiodothyronine induced cardiac hypertrophy on cytosolic protein kinases.
Topics: Animals; Cardiomegaly; Cytosol; Heart Ventricles; Male; Protamine Kinase; Protein Kinases; Rats; Tri | 1978 |
C-myc protooncogene modulates cardiac hypertrophic growth in transgenic mice.
Topics: Actins; Adenylyl Cyclases; Animals; Cardiomegaly; Fibrosis; Heart; Isomerism; Isoproterenol; Mice; M | 1992 |
Energy metabolism of the hypertrophied heart studied by 31P nuclear magnetic resonance.
Topics: Adenosine Triphosphate; Animals; Calcium; Cardiomegaly; Energy Metabolism; Female; Hypertension; In | 1992 |
Fibronectin expression in the normal and hypertrophic rat heart.
Topics: Animals; Cardiomegaly; Desoxycorticosterone; Fibronectins; Glyceraldehyde-3-Phosphate Dehydrogenases | 1992 |
Remodeling of myocyte dimensions in hypertrophic and atrophic rat hearts.
Topics: Animals; Aorta; Atrophy; Body Weight; Cardiomegaly; Female; Heart; Heart Transplantation; In Vitro T | 1991 |
Isoprenaline-induced increase in mRNA levels of inhibitory G-protein alpha-subunits in rat heart.
Topics: Animals; Autoradiography; Blotting, Northern; Cardiomegaly; GTP-Binding Proteins; Heart Diseases; He | 1991 |
The influence of cold stress on the myosin heavy chain expression of cardiac and smooth muscle in normotensive and spontaneously hypertensive female rats.
Topics: Animals; Blotting, Western; Cardiomegaly; Cold Temperature; Female; Isoenzymes; Muscle, Smooth; Myoc | 1991 |
Cardiac ornithine decarboxylase of diabetic spontaneously hypertensive rat: effects of insulin and thyroid hormone treatment.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Diabetes Mellitus, Experimental; Heart Rate; Hyp | 1990 |
Inotropic response of the rat heart during development and regression of triiodothyronine-induced hypertrophy.
Topics: Adrenergic beta-Agonists; Animals; Body Weight; Calcium Chloride; Cardiac Output; Cardiomegaly; Fema | 1989 |
Antihypertensive effect of thyroidectomy in SHR: associated changes in heart performance.
Topics: Age Factors; Animals; Blood Pressure; Body Weight; Cardiomegaly; Female; Heart; Heart Rate; Hyperten | 1986 |
Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals.
Topics: Animals; Aortic Coarctation; Cardiomegaly; Gene Expression Regulation; Heart Atria; Heart Ventricles | 1987 |
Dynamic stiffness of barium-contractured cardiac muscles with different speeds of contraction.
Topics: Animals; Animals, Newborn; Atrial Function; Barium; Biomechanical Phenomena; Cardiomegaly; Hyperthyr | 1987 |
Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.
Topics: Aging; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Fetus; Gene Expression Re | 1988 |
Primary hypothyroidism in severe chronic heart failure.
Topics: Adult; Aged; Cardiomegaly; Euthyroid Sick Syndromes; Female; Heart Failure; Heart Function Tests; Hu | 1988 |
Sucrose feeding prevents changes in myosin isoenzymes and sarcoplasmic reticulum Ca2+-pump ATPase in pressure-loaded rat heart.
Topics: Animals; Blood Glucose; Calcium-Transporting ATPases; Cardiomegaly; Isoenzymes; Male; Myosins; Organ | 1988 |
Diastolic characteristics and cardiac energetics of isolated hearts exposed to volume and pressure overload.
Topics: Animals; Cardiomegaly; Coronary Circulation; Diastole; Female; Heart; Hypertension; Hyperthyroidism; | 1988 |
The influence of the plasma inorganic iodine concentration on thyroid function in dehalogenase deficiency.
Topics: Adult; Cardiomegaly; Goiter; Humans; Hypothyroidism; Iodine; Iodine Radioisotopes; Male; Metabolism, | 1967 |
Size of cardiac ventricles in experimental hyperthyroidism in the rat.
Topics: Animals; Body Weight; Cardiomegaly; Heart Ventricles; Hyperthyroidism; Male; Myocardium; Organ Size; | 1969 |
Effect of exogenous triiodothyronine on weight and composition of the heart in rats.
Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Male; Myocardium; Organ Size; Rats; Triiodot | 1973 |