triiodothyronine has been researched along with Cardiac Output, Low in 11 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is strong clinical and experimental evidence that altered thyroid homeostasis negatively affects survival in cardiac patients, but a negative effect of the low triiodothyronine (T3) syndrome on the outcome of coronary artery bypass grafting (CABG) has not been demonstrated." | 7.80 | The low triiodothyronine syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting. ( Berti, S; Cerillo, AG; Clerico, A; Glauber, M; Haxhiademi, D; Iervasi, G; Kallushi, E; Miceli, A; Murzi, M; Storti, S, 2014) |
| "This study evaluates the efficacy and safety of oral triiodothyronine on time to extubation for infants less than 5 months undergoing heart surgery in Indonesia, and primarily relates to patients in emerging programs with high malnutrition and mortality." | 5.51 | Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass. ( Fakhri, D; Haas, NA; Lopolisa, A; Marwali, EM; Portman, MA; Rayhan, M; Roebiono, PS; Sani, AA; Slee, A, 2022) |
| "There is strong clinical and experimental evidence that altered thyroid homeostasis negatively affects survival in cardiac patients, but a negative effect of the low triiodothyronine (T3) syndrome on the outcome of coronary artery bypass grafting (CABG) has not been demonstrated." | 3.80 | The low triiodothyronine syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting. ( Berti, S; Cerillo, AG; Clerico, A; Glauber, M; Haxhiademi, D; Iervasi, G; Kallushi, E; Miceli, A; Murzi, M; Storti, S, 2014) |
| "We tested the validity of low cardiac output syndrome (LCOS), derived using clinical parameters and laboratory data, by comparing the LCOS diagnosis with objective parameters commonly measured in a cardiac intensive care unit (CCU) setting." | 2.90 | Oral Triiodothyronine Supplementation Decreases Low Cardiac Output Syndrome After Pediatric Cardiac Surgery. ( Batubara, JRL; Caesa, P; Darmaputri, S; Djer, MM; Fakhri, D; Haas, NA; Marwali, EM; Munasir, ZM; Portman, MA; Roebiono, PS; Sani, AA; Satroasmoro, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Marwali, EM | 2 |
| Lopolisa, A | 1 |
| Sani, AA | 2 |
| Rayhan, M | 1 |
| Roebiono, PS | 2 |
| Fakhri, D | 2 |
| Haas, NA | 3 |
| Slee, A | 1 |
| Portman, MA | 2 |
| Caesa, P | 1 |
| Darmaputri, S | 1 |
| Djer, MM | 1 |
| Munasir, ZM | 1 |
| Batubara, JRL | 1 |
| Satroasmoro, S | 1 |
| Cerillo, AG | 1 |
| Storti, S | 1 |
| Kallushi, E | 1 |
| Haxhiademi, D | 1 |
| Miceli, A | 1 |
| Murzi, M | 1 |
| Berti, S | 1 |
| Glauber, M | 1 |
| Clerico, A | 1 |
| Iervasi, G | 2 |
| Conte, JV | 1 |
| Camphausen, CK | 1 |
| Pingitore, A | 1 |
| Barison, A | 1 |
| Prontera, C | 1 |
| Pratali, L | 1 |
| Emdin, M | 1 |
| Giannessi, D | 1 |
| Neglia, D | 1 |
| Sinci, V | 1 |
| Soncul, H | 1 |
| Gunaydin, S | 1 |
| Halit, V | 1 |
| Gokgoz, L | 1 |
| Tatlican, O | 1 |
| Yener, A | 1 |
| Bilgehan, A | 1 |
| Ersoz, A | 1 |
| Nishino, M | 1 |
| Kimura, T | 1 |
| Kanda, T | 1 |
| Kotajima, N | 1 |
| Yoshida, A | 1 |
| Kuwabara, A | 1 |
| Tamama, K | 1 |
| Fukumura, Y | 1 |
| Kobayashi, I | 1 |
| Holland, FW | 1 |
| Brown, PS | 1 |
| Clark, RE | 2 |
| Novitzky, D | 1 |
| Cooper, DK | 1 |
| Swanepoel, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Tetronine (Sodium Liothyronine) for Infants & Children Undergoing Cardiopulmonary Bypass in a Middle Income Nation (OTICC Study)[NCT02222532] | Phase 3 | 224 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for triiodothyronine and Cardiac Output, Low
| Article | Year |
|---|---|
Indonesian Study: Triiodothyronine for Infants Less than 5 Months Undergoing Cardiopulmonary Bypass.
Topics: Cardiac Output, Low; Cardiopulmonary Bypass; Double-Blind Method; Humans; Indonesia; Infant; Malnutr | 2022 |
Oral Triiodothyronine Supplementation Decreases Low Cardiac Output Syndrome After Pediatric Cardiac Surgery.
Topics: Cardiac Output; Cardiac Output, Low; Cardiopulmonary Bypass; Child; Female; Heart Defects, Congenita | 2019 |
9 other studies available for triiodothyronine and Cardiac Output, Low
| Article | Year |
|---|---|
The low triiodothyronine syndrome: a strong predictor of low cardiac output and death in patients undergoing coronary artery bypass grafting.
Topics: Aged; Cardiac Output, Low; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Prognosis; Syn | 2014 |
Invited commentary.
Topics: Cardiac Output, Low; Coronary Artery Bypass; Female; Humans; Male; Triiodothyronine | 2014 |
Triiodothyronine in neonatal heart surgery: Looking for an answer.
Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cardiotonic Agents; Heart | 2006 |
Early activation of an altered thyroid hormone profile in asymptomatic or mildly symptomatic idiopathic left ventricular dysfunction.
Topics: Aged; Cardiac Output, Low; Female; Hormones; Humans; Inflammation; Interleukin-6; Male; Middle Aged; | 2006 |
The effects of thyroid hormones on the heart following global ischemia. A clinical and experimental study.
Topics: Aged; Animals; Cardiac Output, Low; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Disease | 1994 |
Circulating interleukin-6 significantly correlates to thyroid hormone in acute myocardial infarction but not in chronic heart failure.
Topics: Aged; Cardiac Output, Low; Female; Humans; Interleukin-6; Male; Middle Aged; Myocardial Infarction; | 2000 |
Acute severe postischemic myocardial depression reversed by triiodothyronine.
Topics: Acute Disease; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Card | 1992 |
Triiodothyronine: to be or not to be, that is the question.
Topics: Animals; Cardiac Output, Low; Cardiopulmonary Bypass; Humans; Kidney; Myocardial Contraction; Oxidat | 1991 |
Inotropic effect of triiodothyronine (T3) in low cardiac output following cardioplegic arrest and cardiopulmonary bypass: an initial experience in patients undergoing open heart surgery.
Topics: Cardiac Output, Low; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Heart Arrest, Indu | 1989 |