Page last updated: 2024-11-08

triiodothyronine and Carcinoma

triiodothyronine has been researched along with Carcinoma in 76 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.

Research Excerpts

ExcerptRelevanceReference
"We measured serum thyroxine (T4), free T4, 3,5,3-triiodothyronine (T3), free T3, reverse T3 (rT3), and TSH concentrations at baseline and after 26 wk in 21 patients with progressive nonmedullary thyroid carcinoma treated with sorafenib."9.14Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. ( Abdulrahman, RM; Corssmit, EP; Gelderblom, H; Hoftijzer, H; Hovens, GC; Kapiteijn, E; Pereira, AM; Reiners, C; Romijn, JA; Smit, JW; Verburg, E; Verloop, H; Visser, TJ, 2010)
"To examine the effects of triiodothyronine (T3), 17beta-estradiol (E2), and tamoxifen (TAM) on transforming growth factor (TGF)-alpha gene expression in primary breast cancer cell cultures and interactions between the different treatments."7.74Tamoxifen inhibits transforming growth factor-alpha gene expression in human breast carcinoma samples treated with triiodothyronine. ( Brentani, MM; Conde, SJ; Katayama, ML; Luvizotto, RA; Nogueira, CR; Síbio, MT, 2008)
"A comparative analysis of triiodothyronine (T3) and thyroxine (T4) distribution in organs and tissues of tumour-bearing and intact mice conducted wih 125J labelled T3 and T4 has shown considerable differences in the accumulation character of these hormones in mice with Lewis carcinoma and in intact animals in the liver, kidneys, lungs, adrenal glands, lymphatic nodes."7.67[Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma]. ( Dedenkov, AN; Norets, TA; Petrova, GA; Smoryzanova, OA; Vereshchagina, GV, 1985)
"A patient with thyrotoxicosis due to a triiodothyronine (T3)-secreting autonomous adenoma is described."7.66Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics. ( Carriere, DP; Croxson, MS; Panke, TW; Parker, JW; Rosoff, L; Warner, NE, 1978)
"We measured serum thyroxine (T4), free T4, 3,5,3-triiodothyronine (T3), free T3, reverse T3 (rT3), and TSH concentrations at baseline and after 26 wk in 21 patients with progressive nonmedullary thyroid carcinoma treated with sorafenib."5.14Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination. ( Abdulrahman, RM; Corssmit, EP; Gelderblom, H; Hoftijzer, H; Hovens, GC; Kapiteijn, E; Pereira, AM; Reiners, C; Romijn, JA; Smit, JW; Verburg, E; Verloop, H; Visser, TJ, 2010)
" In this study we demonstrated that T3 induced proliferation in papillary thyroid carcinoma cell lines concomitantly with an up-regulation of cyclin D1 expression, that is a critical mitogen-regulated cell-cycle control element."3.80T3 enhances thyroid cancer cell proliferation through TRβ1/Oct-1-mediated cyclin D1 activation. ( Andò, S; Aquila, S; Bonofiglio, D; Catalano, S; Lanzino, M; Panza, S; Perri, A; Qi, H; Rizza, P; Rovito, D; Vizza, D, 2014)
"Thyroid function was measured by means of thyroid stimulating hormone (TSH), free thyroxine (FT4) and free triiodthyronine (FT3) in 43 patients who had nonthyroid head-neck carcinomas treated by radiotherapy or radiotherapy in combination with other modalities."3.80Hypothyroidism after radiotherapy of head and neck cancer. ( Bernát, L; Hrušák, D, 2014)
"To examine the effects of triiodothyronine (T3), 17beta-estradiol (E2), and tamoxifen (TAM) on transforming growth factor (TGF)-alpha gene expression in primary breast cancer cell cultures and interactions between the different treatments."3.74Tamoxifen inhibits transforming growth factor-alpha gene expression in human breast carcinoma samples treated with triiodothyronine. ( Brentani, MM; Conde, SJ; Katayama, ML; Luvizotto, RA; Nogueira, CR; Síbio, MT, 2008)
"A comparative analysis of triiodothyronine (T3) and thyroxine (T4) distribution in organs and tissues of tumour-bearing and intact mice conducted wih 125J labelled T3 and T4 has shown considerable differences in the accumulation character of these hormones in mice with Lewis carcinoma and in intact animals in the liver, kidneys, lungs, adrenal glands, lymphatic nodes."3.67[Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma]. ( Dedenkov, AN; Norets, TA; Petrova, GA; Smoryzanova, OA; Vereshchagina, GV, 1985)
" Homogenates of human thyroid follicular adenoma and carcinomas were incubated with [125I]T4 and dithiothreitol (DTT) at 37 C for 60 min under N2 gas."3.66Triiodothyronine generation from thyroxine in human thyroid: enhanced conversion in Graves' thyroid tissue. ( Imura, H; Inada, M; Ishii, H; Mashio, Y; Naito, K; Nishikawa, M; Tanaka, K, 1981)
"A patient with thyrotoxicosis due to a triiodothyronine (T3)-secreting autonomous adenoma is described."3.66Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics. ( Carriere, DP; Croxson, MS; Panke, TW; Parker, JW; Rosoff, L; Warner, NE, 1978)
"Triiodothyronine was lower in the affected fish than in controls."1.42CHARACTERIZATION OF A FOLLICULAR CELL CARCINOMA OF THE THYROID IN A YELLOWBAR ANGELFISH (POMACANTHUS MACULOSUS). ( Nollens, HH; Schmitt, TL; Simeone, CA; St Leger, J, 2015)
"In patients with differentiated thyroid cancer (DTC), the stimulated serum thyroglobulin (Tg) level at radioiodine ablation is a known predictive factor of persistent disease."1.40Stimulated thyroglobulin level at ablation in differentiated thyroid cancer: the impact of treatment preparation modalities and tumor burden. ( Bardet, S; Blanchard, D; Ciappuccini, R; de Raucourt, D; Hardouin, J; Heutte, N; Quak, E; Rame, JP; Vaur, D, 2014)
"Thyroid hormone resistance syndrome is characterized by a reduced target tissue response to the action of thyroid hormone, which leads to high levels of free thyroxine and free triiodothyronine with non-suppressed levels of thyrotropin (TSH)."1.39Differentiated thyroid carcinoma in a girl with resistance to thyroid hormone management with triiodothyroacetic acid. ( Antonia Pérez-Lázaro, M; Isabel del Olmo-García, M; León-de Zayas, B; Merino-Torres, JF; Moreno-Macián, F; Navas-de Solis, S; Ramos-Prol, A, 2013)
"We measured D3 expression in 6 colon cancer cell lines and human tumors and correlated it with the activity of the β-catenin/TCF complex."1.38β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells. ( Ambrosio, R; Casillo, A; Dentice, M; Fenzi, G; Iaccarino, A; Larsen, PR; Luongo, C; Salvatore, D; Sibilio, A; Troncone, G, 2012)
"In Patient 1, histology showed a papillary thyroid carcinoma pT2."1.37Differentiated thyroid cancer in two patients with resistance to thyroid hormone. ( Capoluongo, E; Concolino, P; Corsello, SM; Locantore, P; Lovicu, RM; Paragliola, RM; Pontecorvi, A; Senes, P, 2011)
"Thyrotropin (TSH) changes in extreme primary hypothyroidism include increased secretion, slowed degradation, and diminished or absent TSH circadian rhythms."1.36TSH regulation dynamics in central and extreme primary hypothyroidism. ( DiStefano, JJ; Eisenberg, MC; Marsili, A; Pinchera, A; Santini, F, 2010)
"Body weights were unaffected by PCN treatment, but were reduced 21% after 19 weeks of PCB treatment compared to control."1.32Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB). ( Habeebu, SM; Klaassen, CD; Muppidi, JR; Vansell, NR, 2004)
"Eleven patients with head and neck cancer (ten men, one woman; mean age, 65 years) (larynx, six; oropharynx, two; tongue, one; skin, one; thyroid, one) with regional lymph node enlargements either in contiguity or firmly adherent to the vascular structures of the neck have been treated by means of external microwaves (915, 434 MHz) applicators."1.28Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis. ( Airoldi, M; Brossa, PC; D'Alberto, M; Gabriele, P; Pedani, F; Ragona, R; Tseroni, V, 1990)
"Plasma T3 levels were reduced in both breast cancer group, but were reduced only in colonic cancer patients with systemic metastases."1.26Plasma thyronine levels in carcinoma of the breast and colon. ( Davis, TE; Rose, DP, 1981)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199038 (50.00)18.7374
1990's13 (17.11)18.2507
2000's4 (5.26)29.6817
2010's20 (26.32)24.3611
2020's1 (1.32)2.80

Authors

AuthorsStudies
Haas, M1
Lein, A1
Fuereder, T1
Schnoell, J1
Brkic, FF1
Campion, NJ1
Liu, DT1
Kadletz-Wanke, L1
Heiduschka, G1
Jank, BJ1
Ramos-Prol, A1
Antonia Pérez-Lázaro, M1
Isabel del Olmo-García, M1
León-de Zayas, B1
Moreno-Macián, F1
Navas-de Solis, S1
Merino-Torres, JF1
Lin, Z2
Chen, L2
Fang, Y1
Cai, A1
Zhang, T1
Wu, VW2
Perri, A1
Catalano, S1
Bonofiglio, D1
Vizza, D1
Rovito, D1
Qi, H1
Aquila, S1
Panza, S1
Rizza, P1
Lanzino, M1
Andò, S1
Bernát, L1
Hrušák, D1
Figueiredo, NB1
Cestari, SH1
Conde, SJ2
Luvizotto, RA2
De Sibio, MT1
Perone, D1
Katayama, ML2
Carraro, DM1
Brentani, HP1
Brentani, MM3
Nogueira, CR3
Ciappuccini, R1
Hardouin, J1
Heutte, N1
Vaur, D1
Quak, E1
Rame, JP1
Blanchard, D1
de Raucourt, D1
Bardet, S1
Gesing, J1
Pfaeffle, R1
Christiansen, H1
Keller, A1
Lincke, T1
Lamesch, P1
Sabri, O1
Kiess, W1
Simeone, CA1
St Leger, J1
Schmitt, TL1
Nollens, HH1
Ito, M2
Miyauchi, A2
Kang, S1
Hisakado, M1
Yoshioka, W1
Ide, A1
Kudo, T2
Nishihara, E2
Kihara, M2
Ito, Y3
Kobayashi, K2
Miya, A2
Fukata, S1
Nakamura, H1
Amino, N2
Rovcanin, BR1
Gopcevic, KR1
Kekic, DLj1
Zivaljevic, VR1
Diklic, ADj1
Paunovic, IR1
Hassan, AQ1
Koh, JT1
Síbio, MT1
Abdulrahman, RM1
Verloop, H1
Hoftijzer, H1
Verburg, E1
Hovens, GC1
Corssmit, EP1
Reiners, C1
Gelderblom, H1
Pereira, AM1
Kapiteijn, E1
Romijn, JA1
Visser, TJ1
Smit, JW1
Lin, J1
Feng, H1
Emerson, CH1
Eisenberg, MC1
Santini, F1
Marsili, A1
Pinchera, A1
DiStefano, JJ1
Jazdzewski, K1
Boguslawska, J1
Jendrzejewski, J1
Liyanarachchi, S1
Pachucki, J1
Wardyn, KA1
Nauman, A1
de la Chapelle, A1
Paragliola, RM1
Lovicu, RM1
Locantore, P1
Senes, P1
Concolino, P1
Capoluongo, E1
Pontecorvi, A1
Corsello, SM1
Malehmir, M1
Haghpanah, V1
Larijani, B1
Ahmadian, S1
Alimoghaddam, K1
Heshmat, R1
Ghavamzadeh, A1
Adabi, K1
Ghaffari, SH1
Lee, DH1
Kim, HK1
Kang, HC1
Joo, YE1
Jang, HC1
Yoon, TM1
Lee, JK2
Lim, SC1
Morita, S1
Takamura, Y1
Kubota, S1
Dentice, M1
Luongo, C1
Ambrosio, R1
Sibilio, A1
Casillo, A1
Iaccarino, A1
Troncone, G1
Fenzi, G1
Larsen, PR1
Salvatore, D1
SEELICH, F1
SEIPEL, H1
PANTLITSCHKO, M1
SHIMA, T1
MOLNAR, GD1
COLBY, MY1
WOOLNER, LB1
SALVATORE, G1
Vansell, NR1
Muppidi, JR1
Habeebu, SM1
Klaassen, CD1
Izotova, IA1
Firsova, PP1
Matveenko, EG1
Harvard, CW1
Tegler, L1
Gillquist, J1
Lindvall, R1
Almqvist, S1
Cheng, SY1
Demidov, VP1
Agranat, VZ1
Ol'shanskiĭ, VO1
Babakulyeva, D1
Voronetskiĭ, IB1
Mizukami, Y1
Matsubara, F1
Hashimoto, T1
Haratake, J1
Terahata, S1
Noguchi, M1
Hirose, K1
Rose, DP1
Davis, TE1
Arnold, DL1
Krewski, DR1
Junkins, DB1
McGuire, PF1
Moodie, CA1
Munro, IC1
Ishii, H1
Inada, M1
Tanaka, K1
Mashio, Y1
Naito, K1
Nishikawa, M1
Imura, H1
Kawaoi, A1
Okano, T1
Nemoto, N1
Shiina, Y1
Shikata, T1
Fujimoto, Y1
Ohara, T1
Sethi, VK1
David, E1
Rosen, IB1
Bain, J1
James, J1
Kirsh, JC1
Francia, G1
Davì, MV1
Petroziello, A1
Sussi, PL1
Marks, SL1
Koblik, PD1
Hornof, WJ1
Feldman, EC1
Lukinac, L1
Franceschi, M1
Nöthig-Hus, D1
Lechpammer, S1
Tomasić, J1
Vranesić, B1
Pape, E1
Kusić, Z1
Pujol, P1
Osman, A1
Bringer, J1
Jaffiol, C1
Alagöl, F1
Tanakol, R1
Boztepe, H1
Kapran, Y1
Terzioglu, T1
Dizdaroglu, F1
Yasuhara, K1
Koujitani, T1
Takegawa, K1
Nasu, M1
Onodera, H1
Takagi, H1
Hirose, M1
Mitsumori, K1
Nagasaka, A1
Hidaka, H1
Arango, A1
Lester, JL1
Martinez, OV1
Malinin, TI1
Zeppa, R1
Panke, TW1
Croxson, MS1
Parker, JW1
Carriere, DP1
Rosoff, L1
Warner, NE1
Thom, AF1
Marquezine, FJ1
Kieffer, J1
Ferraz, AR1
Netto, A1
Toledo, AC1
Yao, Y1
Busnardo, B1
Girelli, ME1
Cimitan, M1
Casara, D1
Bui, F1
Lassi, C1
Argenti, G1
Hasen, J1
Goldiner, M1
Volpert, EM1
Prezyna, AP1
Gaeta, JF1
Koepf, GF1
Staunton, MD1
Greening, WP1
Mercier-Bodard, C1
Nivet, V1
Baulieu, EE1
Gabuniia, RI1
Romanova, LF1
Pinkera, A1
Matiakin, EG1
Duditskaia, TK1
Hupart, KH1
DeFesi, CR1
Katz, CP1
Shapiro, LE1
Surks, MI1
Airoldi, M1
Gabriele, P1
Brossa, PC1
Pedani, F1
Tseroni, V1
D'Alberto, M1
Ragona, R1
Langer, HJ1
Leicht, E1
Koch, B1
Weinheimer, B1
Berberich, R1
Strohfeldt, P1
Weinges, KF1
Wang, RL1
Tan, YB1
Gordon, PR1
Stall, GM1
Gilchrest, BA1
Kaplan, MM1
Kitahori, Y1
Ohshima, M1
Matsuki, H1
Konishi, N1
Hashimoto, H1
Minami, S1
Thamavit, W1
Hiasa, Y1
Dedenkov, AN1
Petrova, GA1
Smoryzanova, OA1
Norets, TA1
Vereshchagina, GV1
Lievre, JA1
Benichou, C1
Williams, DC1
Thomas-Morvan, C1
Nataf, B1
Tubiana, M1
Samaan, NA1
Beceiro, JR1
Hill, CS1
Haynie, TP1
Glenn, HJ1
Hill, LD1
Beebe, HG1
Hipp, R1
Jones, HW1
Desai, KB1
Mehta, MN1
Patel, MC1
Sharma, SM1
Ramanna, L1
Ganatra, RD1
Sakoda, M1
Otsuki, M1
Hiroshige, N1
Kanao, K1
Yagi, A1
Hoffmann, G1
Gehring, D1
Pfannenstiel, P1
Taylor, S1
Davis, PW1
Wahner, HW1
Cuello, C1
Aljure, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sorafenib as Adjuvant to Radioiodine Therapy in Non-Medullary Thyroid Carcinoma[NCT00887107]Phase 232 participants (Actual)Interventional2007-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for triiodothyronine and Carcinoma

ArticleYear
The thyroid and ageing.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:1

    Topics: Age Factors; Aged; Aging; Alpha-Globulins; Animals; Carcinoma; Humans; Hyperthyroidism; Hypothyroidi

1981
Anaplastic thyroid cancer with transient thyrotoxicosis: case report and literature review.
    Thyroid : official journal of the American Thyroid Association, 1999, Volume: 9, Issue:10

    Topics: Biopsy; Carcinoma; Fatal Outcome; Female; Goiter, Nodular; Humans; Middle Aged; Propranolol; Thyroid

1999
Steroid hormones and breast cancer.
    Advances in steroid biochemistry and pharmacology, 1974, Volume: 4, Issue:0

    Topics: Adrenal Cortex; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Age Factors; Binding Sit

1974

Trials

1 trial available for triiodothyronine and Carcinoma

ArticleYear
Sorafenib-induced hypothyroidism is associated with increased type 3 deiodination.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:8

    Topics: Aged; Aged, 80 and over; Benzenesulfonates; Carcinoma; Female; Humans; Hypothyroidism; Male; Middle

2010

Other Studies

72 other studies available for triiodothyronine and Carcinoma

ArticleYear
Low free triiodothyronine and immune-related hyperthyroidism are associated with overall and progression-free survival in head and neck squamous cell carcinoma treated with pembrolizumab.
    International immunopharmacology, 2023, Volume: 123

    Topics: Antibodies, Monoclonal, Humanized; Carcinoma; Head and Neck Neoplasms; Humans; Hyperthyroidism; Prog

2023
Differentiated thyroid carcinoma in a girl with resistance to thyroid hormone management with triiodothyroacetic acid.
    Journal of pediatric endocrinology & metabolism : JPEM, 2013, Volume: 26, Issue:1-2

    Topics: Carcinoma; Carcinoma, Papillary; Cell Differentiation; Child; Female; Humans; Thyroid Cancer, Papill

2013
Longitudinal study on the correlations of thyroid antibody and thyroid hormone levels after radiotherapy in patients with nasopharyngeal carcinoma with radiation-induced hypothyroidism.
    Head & neck, 2014, Volume: 36, Issue:2

    Topics: Adult; Aged; Autoantibodies; Biomarkers; Carcinoma; Female; Follow-Up Studies; Humans; Hypothyroidis

2014
T3 enhances thyroid cancer cell proliferation through TRβ1/Oct-1-mediated cyclin D1 activation.
    Molecular and cellular endocrinology, 2014, Jan-25, Volume: 382, Issue:1

    Topics: Carcinoma; Carcinoma, Papillary; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Enzyme Activation;

2014
Hypothyroidism after radiotherapy of head and neck cancer.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2014, Volume: 42, Issue:4

    Topics: Aged; Carcinoma; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Follow-Up Studies;

2014
Estrogen-responsive genes overlap with triiodothyronine-responsive genes in a breast carcinoma cell line.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Breast Neoplasms; Carcinoma; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-

2014
Stimulated thyroglobulin level at ablation in differentiated thyroid cancer: the impact of treatment preparation modalities and tumor burden.
    European journal of endocrinology, 2014, Volume: 171, Issue:2

    Topics: Adenocarcinoma, Follicular; Adult; Aged; Carcinoma; Carcinoma, Papillary; Female; Humans; Iodine Rad

2014
Papillary thyroid carcinoma in an adolescent girl with graves' disease.
    Klinische Padiatrie, 2014, Volume: 226, Issue:6-7

    Topics: Adolescent; Carcinoma; Carcinoma, Papillary; Combined Modality Therapy; Female; Graves Disease; Huma

2014
CHARACTERIZATION OF A FOLLICULAR CELL CARCINOMA OF THE THYROID IN A YELLOWBAR ANGELFISH (POMACANTHUS MACULOSUS).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2015, Volume: 46, Issue:2

    Topics: Animals; Carcinoma; Fish Diseases; Fishes; Thyroid Neoplasms; Thyrotropin; Triiodothyronine

2015
Effect of the presence of remnant thyroid tissue on the serum thyroid hormone balance in thyroidectomized patients.
    European journal of endocrinology, 2015, Volume: 173, Issue:3

    Topics: Adult; Aged; Carcinoma; Carcinoma, Papillary; Cohort Studies; Female; Hormone Replacement Therapy; H

2015
Papillary Thyroid Carcinoma: A Malignant Tumor with Increased Antioxidant Defense Capacity.
    The Tohoku journal of experimental medicine, 2016, Volume: 240, Issue:2

    Topics: Antioxidants; Carcinoma; Carcinoma, Papillary; Case-Control Studies; Demography; Humans; Linear Mode

2016
Selective chemical rescue of a thyroid-hormone-receptor mutant, TRbeta(H435Y), identified in pituitary carcinoma and resistance to thyroid hormone.
    Angewandte Chemie (International ed. in English), 2008, Volume: 47, Issue:38

    Topics: Amino Acid Motifs; Amino Acid Substitution; Carcinoma; Histidine; Humans; Ligands; Models, Chemical;

2008
Tamoxifen inhibits transforming growth factor-alpha gene expression in human breast carcinoma samples treated with triiodothyronine.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Carcinoma; Cell Culture Techniques; Down-Regulatio

2008
A longitudinal study on the radiation-induced thyroid gland changes after external beam radiotherapy of nasopharyngeal carcinoma.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:1

    Topics: Adult; Aged; Carcinoma; Female; Humans; Longitudinal Studies; Male; Middle Aged; Nasopharyngeal Carc

2011
Anthropomorphic thyroidopathies?
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:11

    Topics: Adult; Body Mass Index; Carcinoma; Child, Preschool; Fasting; Humans; Hypothyroidism; Insulin; Lepti

2010
TSH regulation dynamics in central and extreme primary hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:11

    Topics: Carcinoma; Circadian Rhythm; Computer Simulation; Feedback; Humans; Hypothyroidism; Iodine Radioisot

2010
Thyroid hormone receptor beta (THRB) is a major target gene for microRNAs deregulated in papillary thyroid carcinoma (PTC).
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:3

    Topics: 3' Untranslated Regions; Amyloid beta-Protein Precursor; Apoptosis; Blotting, Western; Carcinoma; Ca

2011
Differentiated thyroid cancer in two patients with resistance to thyroid hormone.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:7

    Topics: Carcinoma; Carcinoma, Papillary; Humans; Male; Middle Aged; Thyroid Cancer, Papillary; Thyroid Hormo

2011
Multifaceted suppression of aggressive behavior of thyroid carcinoma by all-trans retinoic acid induced re-differentiation.
    Molecular and cellular endocrinology, 2012, Jan-02, Volume: 348, Issue:1

    Topics: Antigens, Differentiation; Antineoplastic Agents; Carcinoma; Cell Dedifferentiation; Cell Differenti

2012
Thyroid abscess with esophageal perforation in papillary thyroid cancer.
    Thyroid : official journal of the American Thyroid Association, 2012, Volume: 22, Issue:5

    Topics: Abscess; Blood Sedimentation; C-Reactive Protein; Carcinoma; Carcinoma, Papillary; Esophageal Perfor

2012
TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy.
    European journal of endocrinology, 2012, Volume: 167, Issue:3

    Topics: Adult; Aged; Carcinoma; Carcinoma, Papillary; Female; Humans; Male; Middle Aged; Preoperative Care;

2012
β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells.
    Gastroenterology, 2012, Volume: 143, Issue:4

    Topics: Adenoma; Animals; beta Catenin; Caco-2 Cells; Cadherins; Carcinoma; Cell Differentiation; Cell Proli

2012
[On the effect of triiodothyroacetic acid (TRIAC) on the metabolism of Ehrlich ascites tumor cells].
    Biochemische Zeitschrift, 1962, Volume: 336

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Thyroid Hormones; Triiodothyronine

1962
[Effects of L-triiodothyronine on growth and radiosensitivity of tumors. 1].
    Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica, 1963, Feb-25, Volume: 22

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Division; Mammary Neoplasms, Animal; Mammary Neop

1963
CLINICS ON ENDOCRINE AND METABOLIC DISEASES. 11. DEMONSTRATION OF THYROID-STIMULATING-HORMONE DEPENDENCE IN A CASE OF METASTATIC CARCINOMA OF THYROID ORIGIN.
    Proceedings of the staff meetings. Mayo Clinic, 1963, Jul-03, Volume: 38

    Topics: Bone Marrow Examination; Carcinoma; Humans; Iodine Isotopes; Metabolic Diseases; Neoplasm Metastasis

1963
[INTRACELLULAR PENETRATION OF THYROID HORMONES].
    Exposes annuels de biochimie medicale, 1964, Volume: 25

    Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Electrophoresis; Erythrocytes; Escheri

1964
Promotion of thyroid tumors in rats by pregnenolone-16alpha-carbonitrile (PCN) and polychlorinated biphenyl (PCB).
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 81, Issue:1

    Topics: Adenoma; Animals; Antithyroid Agents; Body Weight; Carcinoma; Chlorodiphenyl (54% Chlorine); Eating;

2004
[The state of hormonal homeostasis in patients with lung cancer under combined and radiation treatment].
    Voprosy onkologii, 1984, Volume: 30, Issue:12

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Carcinoma; Carcinoma, Squamous Cell; Combined Mo

1984
Secretion rates of thyroxine, triiodothyronine, and reverse triiodothyronine in man during surgery.
    Acta endocrinologica, 1982, Volume: 101, Issue:2

    Topics: Adenoma; Adult; Aged; Carcinoma; Electromagnetic Phenomena; Female; Goiter; Goiter, Nodular; Humans;

1982
Structural similarities in the plasma membrane 3,3',5-triiodo-L-thyronine receptors from human, rat and mouse cultured cells. Analysis by affinity labeling.
    Endocrinology, 1983, Volume: 113, Issue:3

    Topics: Affinity Labels; Animals; Carcinoma; Cell Line; Cell Membrane; Endopeptidases; Fibroblasts; Humans;

1983
[Thyroid activity in patients with thyroid neoplasms].
    Voprosy onkologii, 1983, Volume: 29, Issue:11

    Topics: Adenoma; Adolescent; Adult; Age Factors; Aged; Carcinoma; Female; Humans; Male; Middle Aged; Sex Fac

1983
Primary mucoepidermoid carcinoma in the thyroid gland. A case report including an ultrastructural and biochemical study.
    Cancer, 1984, Apr-15, Volume: 53, Issue:8

    Topics: Adenocarcinoma; Adult; Carcinoma; Diagnosis, Differential; Female; Humans; Lymph Nodes; Microscopy,

1984
Plasma thyronine levels in carcinoma of the breast and colon.
    Archives of internal medicine, 1981, Volume: 141, Issue:9

    Topics: Adult; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Middle Aged;

1981
Reversibility of ethylenethiourea-induced thyroid lesions.
    Toxicology and applied pharmacology, 1983, Volume: 67, Issue:2

    Topics: Adenoma; Animals; Body Weight; Carcinoma; Diet; Dose-Response Relationship, Drug; Ethylenethiourea;

1983
Triiodothyronine generation from thyroxine in human thyroid: enhanced conversion in Graves' thyroid tissue.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:6

    Topics: Adenoma; Carcinoma; Dithiothreitol; Graves Disease; Humans; Hydrogen-Ion Concentration; Kinetics; Th

1981
Simultaneous detection of thyroglobulin (Tg), thyroxine (T4), and Triiodothyronine (T3) in nontoxic thyroid tumors by the immunoperoxidase method.
    The American journal of pathology, 1982, Volume: 108, Issue:1

    Topics: Adenocarcinoma; Adenoma; Carcinoma; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cystadenoma; Hum

1982
[Endocrine aspects of thyroid cancer].
    Horumon to rinsho. Clinical endocrinology, 1982, Volume: 30, Issue:8

    Topics: Adenocarcinoma, Papillary; Adult; Aged; Calcitonin; Carcinoma; Female; Humans; Male; Middle Aged; Th

1982
Non-surgical treatment of thyroid carcinoma.
    Annals of the Academy of Medicine, Singapore, 1981, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma, Papillary; Carcinoma; Humans; Iodine Radioisotopes; Thyroid Neoplasm

1981
Management of the hot thyroid nodule.
    American journal of surgery, 1995, Volume: 170, Issue:5

    Topics: Adenocarcinoma; Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma; D

1995
[Hormonal therapy in differentiated carcinoma of the thyroid gland].
    Chirurgia italiana, 1994, Volume: 46, Issue:4

    Topics: Adenocarcinoma, Follicular; Adenylyl Cyclases; Biomarkers, Tumor; Carcinoma; Carcinoma, Papillary; H

1994
99mTc-pertechnetate imaging of thyroid tumors in dogs: 29 cases (1980-1992).
    Journal of the American Veterinary Medical Association, 1994, Mar-01, Volume: 204, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Medullary; Dog Diseases; Dogs; Female; Lung

1994
Endogenously labeled thyroid hormones (131I-T3/T4) in sera of patients with differentiated thyroid carcinoma.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:3

    Topics: Adult; Carcinoma; Chromatography; Female; Humans; Iodine Radioisotopes; Male; Radionuclide Imaging;

1996
Triiodothyronine mimics the effects of estrogen in breast cancer cell lines.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 59, Issue:3-4

    Topics: Breast Neoplasms; Carcinoma; Cell Division; Estradiol; Estrogen Antagonists; Gene Expression Regulat

1996
Prevention of thyroid neoplasm recurrence with Triac and levothyroxine.
    Clinical endocrinology, 1997, Volume: 46, Issue:1

    Topics: Carcinoma; Drug Therapy, Combination; Humans; Neoplasm Recurrence, Local; Thyroid Neoplasms; Thyroxi

1997
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.
    Carcinogenesis, 2001, Volume: 22, Issue:4

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Hyp

2001
Human thyroid cyclic nucleotide phosphodiesterase. Its characterization and the effect of several hormones on the activity.
    Biochimica et biophysica acta, 1976, Jul-08, Volume: 438, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenoma; Calcium; Carcinoma; Cyclic AMP; Cyclic GMP; Enzyme Act

1976
Bacteriologic and systemic effects of intraoperative segmental bowel preparation with povidone iodine.
    Archives of surgery (Chicago, Ill. : 1960), 1979, Volume: 114, Issue:2

    Topics: Adult; Aged; Bacteria; Carcinoma; Colon; Colonic Diseases; Colonic Neoplasms; Humans; Iodine; Middle

1979
Triiodothyronine-secreting (toxic) adenoma of the thyroid gland: light and electron microscopic characteristics.
    Cancer, 1978, Volume: 41, Issue:2

    Topics: Adenoma; Adult; Carcinoma; Carcinoma, Papillary; Female; Humans; Hyperplasia; Hyperthyroidism; Micro

1978
[Treatment of thyroid carcinoma].
    Revista do Hospital das Clinicas, 1978, Volume: 33, Issue:2

    Topics: Adolescent; Adult; Aged; Carcinoma; Child; Doxorubicin; Female; Follow-Up Studies; Humans; Iodine Ra

1978
Thyroid nodules--benign or malignant? 1. Diagnosis.
    Postgraduate medicine, 1977, Volume: 61, Issue:4

    Topics: Adenoma; Adult; Biopsy, Needle; Carcinoma; Diagnosis, Differential; Female; Humans; Male; Radionucli

1977
Relationships between metastases of differentiated thyroid carcinoma and serum thyrotropin (TSH) levels.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:6

    Topics: Adolescent; Adult; Aged; Carcinoma; Child; Female; Humans; Iodine Radioisotopes; Male; Middle Aged;

1977
Triiodothyronine-producing metastatic follicular thyroid carcinoma.
    Hormone research, 1977, Volume: 8, Issue:4

    Topics: Aged; Carcinoma; Female; Humans; Iodine Radioisotopes; Neoplasm Metastasis; Thyroid Neoplasms; Thyro

1977
Iodoamino acid content and distribution in normal and abnormal human thyroids.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:3

    Topics: Adenoma; Carcinoma; Humans; Monoiodotyrosine; Thyroid Gland; Thyroid Neoplasms; Thyroiditis, Autoimm

1975
Treatment of thyroid cancer in 293 patients.
    The British journal of surgery, 1976, Volume: 63, Issue:4

    Topics: Adenocarcinoma; Adult; Carcinoma; Carcinoma, Papillary; Female; Humans; Iodine Radioisotopes; Lympha

1976
Effects of hormones on SBP mRNA levels in human cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 40, Issue:4-6

    Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometri

1991
[Radioimmunologic analysis in the differential diagnosis of cancer of the thyroid gland].
    Meditsinskaia radiologiia, 1991, Volume: 36, Issue:7

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Biomarkers, Tumor; Carcinoma; Diagnosis, Differential; Female;

1991
Differential response to L-triiodothyronine of anterior pituitary growth hormone messenger ribonucleic acid (mRNA) and beta-thyrotropin mRNA in a hypothyroid Walker 256 carcinoma-bearing rat model of nonthyroidal disease.
    Endocrinology, 1990, Volume: 126, Issue:1

    Topics: Animals; Carcinoma; Growth Hormone; Hypothyroidism; Male; Neoplasm Transplantation; Pituitary Gland,

1990
Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis.
    Cancer, 1990, Feb-15, Volume: 65, Issue:4

    Topics: Aged; Aged, 80 and over; Carcinoma; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Human

1990
[Familial nonneoplastic inappropriate thyrotropin secretion].
    Deutsche medizinische Wochenschrift (1946), 1990, May-25, Volume: 115, Issue:21

    Topics: Carcinoma; Diagnosis, Differential; Drug Therapy, Combination; Female; Goiter; Humans; Middle Aged;

1990
[Immunohistochemical study and lectin distribution of thyroid carcinoma originated from follicular epithelium].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 1990, Volume: 19, Issue:2

    Topics: Adenocarcinoma; Carcinoma; Carcinoma, Papillary; Humans; Immunohistochemistry; Lectins; Thyroglobuli

1990
Phenolic and tyrosyl ring iodothyronine deiodination by the Caco-2 human colon carcinoma cell line.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:12

    Topics: Carcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Absorption; Iodine; Kinetics;

1989
Promoting effect of 2,4-diaminoanisole sulfate on rat thyroid carcinogenesis.
    Cancer letters, 1989, Volume: 45, Issue:2

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Cocarcinogenesis; Hair Dyes; Hair Preparation

1989
[Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma].
    Eksperimental'naia onkologiia, 1985, Volume: 7, Issue:2

    Topics: Animals; Carcinoma; Female; Kinetics; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplan

1985
[Relationships between the thyroid and parathyroid].
    Actualites endocrinologiques, 1973, Volume: 13, Issue:0

    Topics: Blood; Calcitonin; Calcium; Carcinoma; Drug Antagonism; Humans; Hyperthyroidism; Multiple Endocrine

1973
Thyroid proteins and hormone synthesis in human thyroid cancer.
    Acta endocrinologica, 1974, Volume: 76, Issue:4

    Topics: Adenocarcinoma; Carbon Radioisotopes; Carcinoma; Carcinoma, Papillary; Chromatography, Paper; Diiodo

1974
Thyrotropin releasing hormone (TRH) studies in patients with thyroid cancer.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 35, Issue:3

    Topics: Adenocarcinoma; Aged; Carcinoma; Female; Half-Life; Humans; Injections, Intravenous; Iodine; Iodine

1972
Proceedings: Thyroid suppression.
    Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 108, Issue:4

    Topics: Adenocarcinoma; Adult; Carcinoma; Carcinoma, Papillary; Diagnosis, Differential; Female; Humans; Iod

1974
Familial goitre with absence of thyroglobulin and synthesis of thyroid hormones from thyroidal albumin.
    The Journal of endocrinology, 1974, Volume: 60, Issue:3

    Topics: Adolescent; Albumins; Carcinoma; Centrifugation, Density Gradient; Child; Chromatography; Chromatogr

1974
Effect of synthetic thyrotropin-releasing factor (TRF) on pituitary TSH secretion in man.
    Endocrinologia japonica, 1970, Volume: 17, Issue:6

    Topics: Adenoma, Chromophobe; Adrenal Cortex Hormones; Adult; Aged; Blood Proteins; Carcinoma; Craniopharyng

1970
[Evaluation of therapeutic results in thyroid cancer].
    Nuclear-Medizin, 1970, Jul-15, Volume: 9, Issue:2

    Topics: Adult; Age Factors; Aged; Carcinoma; Evaluation Studies as Topic; Follow-Up Studies; Humans; Iodine

1970
A review of the treatment of 222 patients with malignant tumours of the thyroid gland.
    Neoplastic disease at various sites, 1970, Volume: 6

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Bone Neoplasms; Carcinoma; Carcinoma, Papillary; Child; Fem

1970
Hormone-induced regression of medullary (solid) thyroid carcinoma.
    The American journal of medicine, 1968, Volume: 45, Issue:5

    Topics: Carcinoma; Humans; Hypothyroidism; Male; Middle Aged; Neoplasm Metastasis; Radiography; Thyroid Neop

1968