Page last updated: 2024-11-08

triiodothyronine and Cancer of Skin

triiodothyronine has been researched along with Cancer of Skin in 8 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Bexarotene-induced central hypothyroidism (CH), for which levothyroxine (LT4) replacement is recommended, has been shown to be caused by pituitary but not hypothalamic disorder experimentally, though the underlying mechanism in humans remains unclear."8.12Bexarotene-induced central hypothyroidism assessed by TRH stimulation test in cutaneous T-cell lymphoma patients. ( Emoto, M; Hayashi, D; Imanishi, Y; Inaba, M; Kurajoh, M; Miyaoka, D; Morita, A; Nagata, Y; Tateishi, C; Toi, N; Tsuruta, D; Yamada, S, 2022)
"Bexarotene-induced central hypothyroidism (CH), for which levothyroxine (LT4) replacement is recommended, has been shown to be caused by pituitary but not hypothalamic disorder experimentally, though the underlying mechanism in humans remains unclear."4.12Bexarotene-induced central hypothyroidism assessed by TRH stimulation test in cutaneous T-cell lymphoma patients. ( Emoto, M; Hayashi, D; Imanishi, Y; Inaba, M; Kurajoh, M; Miyaoka, D; Morita, A; Nagata, Y; Tateishi, C; Toi, N; Tsuruta, D; Yamada, S, 2022)
"Blocking the PD-1 pathway induces immune-related adverse events (irAEs) which often involve the thyroid gland (thyroid irAEs)."1.51Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab. ( Fujii, T; Hishizawa, M; Inagaki, N; Kawaguchi-Sakita, N; Kim, YH; Kitamura, M; Kitawaki, T; Matsumoto, S; Nomura, M; Otsuka, A; Saito, R; Sakamori, Y; Sone, M; Taura, D; Yamasaki, T; Yamauchi, I; Yasoda, A, 2019)
"Vitiligo is the most common pigmentation-related disorder worldwide."1.37Relevance of autoimmune thyroiditis in children and adolescents with vitiligo. ( Alpay, K; Bahadır, S; Okten, A; Uncu, S; Yaylı, S, 2011)
"Pancreatic cancer was induced by treatment with 40 mg/kg body wt N-nitrosobis-(2-oxopropyl)amine (BOP)."1.27Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice. ( Birt, DF; Bresnick, E; Pelling, JC; Pour, PM; Schweickert, L; Tibbels, MG, 1987)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Toi, N1
Kurajoh, M1
Miyaoka, D1
Nagata, Y1
Yamada, S1
Imanishi, Y1
Hayashi, D1
Tateishi, C1
Inaba, M1
Tsuruta, D1
Morita, A1
Emoto, M1
Yamauchi, I2
Sakane, Y1
Fukuda, Y1
Fujii, T2
Taura, D2
Hirata, M1
Hirota, K1
Ueda, Y1
Kanai, Y1
Yamashita, Y1
Kondo, E1
Sone, M2
Yasoda, A2
Inagaki, N2
Ansorge, C1
Seufert, J1
Meiss, F1
von Bubnoff, D1
Matsumoto, S1
Sakamori, Y1
Kim, YH1
Nomura, M1
Otsuka, A1
Yamasaki, T1
Saito, R1
Kitamura, M1
Kitawaki, T1
Hishizawa, M1
Kawaguchi-Sakita, N1
Uncu, S1
Yaylı, S1
Bahadır, S1
Okten, A1
Alpay, K1
SHERWIN-WEIDENREICH, R1
HERRMANN, F2
WEIDENREICH-SHERWIN, R1
Birt, DF1
Pelling, JC1
Pour, PM1
Tibbels, MG1
Schweickert, L1
Bresnick, E1

Other Studies

8 other studies available for triiodothyronine and Cancer of Skin

ArticleYear
Bexarotene-induced central hypothyroidism assessed by TRH stimulation test in cutaneous T-cell lymphoma patients.
    Endocrine journal, 2022, Jan-28, Volume: 69, Issue:1

    Topics: Bexarotene; Humans; Hypothyroidism; Lymphoma, T-Cell, Cutaneous; Retrospective Studies; Skin Neoplas

2022
Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study.
    Thyroid : official journal of the American Thyroid Association, 2017, Volume: 27, Issue:7

    Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Lung Neoplasm

2017
Sequential occurrence of primary and secondary hypothyroidism during treatment with nivolumab: pitfalls in immuno-oncological therapy and endocrinological diagnostic procedures.
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2018, Volume: 16, Issue:12

    Topics: Adult; Antineoplastic Agents, Immunological; Autoimmune Hypophysitis; Humans; Hydrocortisone; Hypopi

2018
Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Aged; Antineoplastic Agents, Immunological; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxygluco

2019
Relevance of autoimmune thyroiditis in children and adolescents with vitiligo.
    International journal of dermatology, 2011, Volume: 50, Issue:2

    Topics: Adolescent; Age of Onset; Autoantibodies; Child; Child, Preschool; Comorbidity; Female; Humans; Inci

2011
Hair cycle and chemically induced epidermal carcinogenesis in mice receiving tri-iodothyronine. I. Findings after single application of 9,10-dimethyl-1,2-benzanthracene.
    The Journal of investigative dermatology, 1963, Volume: 40

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogenesis; Epidermis; Hair; Mice

1963
HAIR CYCLE AND CHEMICALLY INDUCED EPIDERMAL CARCINOGENESIS IN MICE RECEIVING LIOTHYRONINE. II. FINDINGS AFTER MULTIPLE APPLICATIONS OF METHYLCHOLANTHRENE.
    Dermatologica, 1964, Volume: 128

    Topics: Animals; Carcinogenesis; Epidermis; Hair; Methylcholanthrene; Mice; Neoplasms; Neoplasms, Experiment

1964
Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice.
    Carcinogenesis, 1987, Volume: 8, Issue:7

    Topics: Animals; Body Weight; Brassica; Cricetinae; Dietary Fats; Female; Gallbladder Neoplasms; Male; Mesoc

1987