triiodothyronine has been researched along with Cancer of Prostate in 26 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Men with prostate cancer had serum triiodothyronine that was significantly different than in controls (p = 0." | 5.31 | Serum triiodothyronine is increased in men with prostate cancer and benign prostatic hyperplasia. ( Diamond, EJ; Droller, MJ; Lehrer, S; Stock, RG; Stone, NN, 2002) |
| " In the present study we explored whether androgens (R1881), retinoids (all-trans- and 9-cis-retinoic acid: atRA and 9cRA), deltanoids (1alpha,25-dihydroxycholecalciferol: VD3) and thyroid hormone (triiodothyronine: T3) influence the production of IGFBPs by LNCaP prostatic adenocarcinoma cells and whether the observed changes affect tumor cell growth." | 3.70 | Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNcaP prostatic adenocarcinoma cells. ( Esquenet, M; Goossens, K; Manin, M; Rombauts, W; Swinnen, JV; Verhoeven, G, 1999) |
| "Blood samples from 140 patients with prostate cancer were analyzed preoperatively and stratified according to postoperative histopathological differentiation." | 1.56 | Association of Triiodothyronine Levels With Prostate Cancer Histopathological Differentiation and Tumor Stage. ( Butković, MB; Franceschi, M; Fröbe, A; Jakovčević, D; Jukić, T; Krilić, D; Krušlin, B; Mažuran, B; Milošević, M; Murgić, J; Ovčariček, PP; Ovčariček, S; Ružić, B; Šoipi, Š; Verburg, FA, 2020) |
| "In vitro, in the LNCaP prostate cancer cell line, we found that both T3 and T4 increased the number of viable cells (Trypan blue assay), and only T4 response was fully blocked in the presence of an integrin-binding inhibitor peptide (RGD, arginine-glycine-aspartate)." | 1.56 | A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model. ( Aceves, C; Álvarez, L; Anguiano, B; Delgado-González, E; Montes de Oca, C; Ortiz, Z; Rodríguez-Castelán, J; Sánchez-Tusie, A; Zarco, C, 2020) |
| "This mild hypothyroidism was detected in two of the 96 patients of the control group (2." | 1.33 | Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer. ( Catalán, R; Cecchini, L; Esquena, S; Morote, J; Orsola, A; Planas, J; Raventós, CX; Reventós, J; Salvador, C; Trilla, E, 2005) |
| "Men with prostate cancer had serum triiodothyronine that was significantly different than in controls (p = 0." | 1.31 | Serum triiodothyronine is increased in men with prostate cancer and benign prostatic hyperplasia. ( Diamond, EJ; Droller, MJ; Lehrer, S; Stock, RG; Stone, NN, 2002) |
| "It was only found in hepatoma cells where it is regulated by estradiol, antiestrogen tamoxifen and triiodothyronine, in a similar way as secreted SBP." | 1.28 | Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones. ( Baulieu, EE; Baville, F; Bideux, G; Binart, N; Chambraud, B; Mercier-Bodard, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 7 (26.92) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Erzurumlu, Y | 1 |
| Muhammed, MT | 1 |
| Ovčariček, PP | 1 |
| Fröbe, A | 1 |
| Verburg, FA | 1 |
| Murgić, J | 1 |
| Butković, MB | 1 |
| Ovčariček, S | 1 |
| Mažuran, B | 1 |
| Krušlin, B | 1 |
| Jakovčević, D | 1 |
| Šoipi, Š | 1 |
| Ružić, B | 1 |
| Milošević, M | 1 |
| Krilić, D | 1 |
| Franceschi, M | 1 |
| Jukić, T | 1 |
| Aksoy, O | 1 |
| Pencik, J | 1 |
| Hartenbach, M | 1 |
| Moazzami, AA | 1 |
| Schlederer, M | 1 |
| Balber, T | 1 |
| Varady, A | 1 |
| Philippe, C | 1 |
| Baltzer, PA | 1 |
| Mazumder, B | 1 |
| Whitchurch, JB | 1 |
| Roberts, CJ | 1 |
| Haitel, A | 1 |
| Herac, M | 1 |
| Susani, M | 1 |
| Mitterhauser, M | 1 |
| Marculescu, R | 1 |
| Stangl-Kremser, J | 1 |
| Hassler, MR | 1 |
| Kramer, G | 1 |
| Shariat, SF | 1 |
| Turner, SD | 1 |
| Tichy, B | 1 |
| Oppelt, J | 1 |
| Pospisilova, S | 1 |
| Hartenbach, S | 1 |
| Tangermann, S | 1 |
| Egger, G | 1 |
| Neubauer, HA | 1 |
| Moriggl, R | 1 |
| Culig, Z | 1 |
| Greiner, G | 1 |
| Hoermann, G | 1 |
| Hacker, M | 1 |
| Heery, DM | 1 |
| Merkel, O | 1 |
| Kenner, L | 1 |
| Sánchez-Tusie, A | 1 |
| Montes de Oca, C | 1 |
| Rodríguez-Castelán, J | 1 |
| Delgado-González, E | 1 |
| Ortiz, Z | 1 |
| Álvarez, L | 1 |
| Zarco, C | 1 |
| Aceves, C | 1 |
| Anguiano, B | 1 |
| Bidosee, M | 2 |
| Karry, R | 2 |
| Weiss-Messer, E | 2 |
| Barkey, RJ | 2 |
| Lehrer, S | 1 |
| Diamond, EJ | 1 |
| Stone, NN | 1 |
| Droller, MJ | 1 |
| Stock, RG | 1 |
| Morote, J | 1 |
| Esquena, S | 1 |
| Orsola, A | 1 |
| Salvador, C | 1 |
| Trilla, E | 1 |
| Cecchini, L | 1 |
| Raventós, CX | 1 |
| Planas, J | 1 |
| Catalán, R | 1 |
| Reventós, J | 1 |
| Tsui, KH | 1 |
| Hsieh, WC | 1 |
| Lin, MH | 1 |
| Chang, PL | 1 |
| Juang, HH | 1 |
| Ramberg, H | 1 |
| Eide, T | 1 |
| Krobert, KA | 1 |
| Levy, FO | 1 |
| Dizeyi, N | 1 |
| Bjartell, AS | 1 |
| Abrahamsson, PA | 1 |
| Taskén, KA | 1 |
| Valenti, G | 2 |
| Banchini, A | 2 |
| Denti, L | 1 |
| Zavaroni, D | 2 |
| Zaninovich, AA | 2 |
| Vescovi, PP | 1 |
| Ponticelli, P | 1 |
| Hafez, ES | 1 |
| Hedlund, TE | 1 |
| Miller, GJ | 1 |
| Esquenet, M | 3 |
| Swinnen, JV | 3 |
| Heyns, W | 2 |
| Verhoeven, G | 3 |
| Dutkiewicz, S | 1 |
| Witeska, A | 1 |
| Nauman, A | 1 |
| Van Veldhoven, PP | 1 |
| Denef, C | 1 |
| Zhang, S | 1 |
| Hsieh, ML | 1 |
| Zhu, W | 1 |
| Klee, GG | 1 |
| Tindall, DJ | 1 |
| Young, CY | 1 |
| Goossens, K | 1 |
| Manin, M | 1 |
| Rombauts, W | 1 |
| Mercier-Bodard, C | 2 |
| Nivet, V | 1 |
| Baulieu, EE | 2 |
| Baville, F | 1 |
| Bideux, G | 1 |
| Binart, N | 1 |
| Chambraud, B | 1 |
| Barreca, T | 1 |
| Martorana, G | 1 |
| Franceschini, R | 1 |
| Giberti, C | 1 |
| Brancadoro, MT | 1 |
| Messina, V | 1 |
| Rolandi, E | 1 |
| Eckerström, S | 1 |
| Ronzoni, G | 1 |
| Alquati, P | 1 |
| Pola, P | 1 |
| Alcini, E | 1 |
| Cappelaere, P | 1 |
| Farach, H | 1 |
| Ezrin, C | 1 |
| Volpé, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Assessment of Patients With Clinically Suspected Prostate Cancer After Multiparametric Metabolic Hybrid Imaging to Evaluate Its Potential Clinical Domain: A Prospective, Randomized, Multi-arm, Multi-treatment Clinical Trial[NCT02659527] | Phase 3 | 220 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for triiodothyronine and Cancer of Prostate
| Article | Year |
|---|---|
Direct and indirect effects of estrogens on thyroidal economy of man.
Topics: Estradiol; Estrogens; Humans; Iodine; Male; Prostatic Neoplasms; Protein Binding; Thyroid Diseases; | 1981 |
[Hormone therapy in geriatrics].
Topics: Adrenocorticotropic Hormone; Aged; Androgens; Arteriosclerosis; Breast Neoplasms; Coronary Disease; | 1969 |
24 other studies available for triiodothyronine and Cancer of Prostate
| Article | Year |
|---|---|
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Topics: Androgens; Animals; Endoplasmic Reticulum-Associated Degradation; Humans; Male; Mammals; Prostate; P | 2023 |
Association of Triiodothyronine Levels With Prostate Cancer Histopathological Differentiation and Tumor Stage.
Topics: Aged; Humans; Male; Middle Aged; Neoplasm Grading; Neoplasm Staging; Preoperative Period; Prospectiv | 2020 |
Thyroid and androgen receptor signaling are antagonized by μ-Crystallin in prostate cancer.
Topics: Cell Line, Tumor; Choline; Cohort Studies; Crystallins; Down-Regulation; Gene Expression Profiling; | 2021 |
A rise in T3/T4 ratio reduces the growth of prostate tumors in a murine model.
Topics: Adenocarcinoma; Animals; Apoptosis; Body Weight; Cell Proliferation; Disease Models, Animal; Male; M | 2020 |
Regulation of growth hormone receptors in human prostate cancer cell lines.
Topics: Androgen Antagonists; Androgens; Cell Line, Tumor; Culture Media; Culture Media, Serum-Free; Estradi | 2009 |
Growth hormone affects gene expression and proliferation in human prostate cancer cells.
Topics: Cell Line, Tumor; Estradiol; Gene Expression Regulation; Human Growth Hormone; Humans; Insulin-Like | 2011 |
Serum triiodothyronine is increased in men with prostate cancer and benign prostatic hyperplasia.
Topics: Biomarkers; Biomarkers, Tumor; Humans; Immunoassay; Male; Prostatic Hyperplasia; Prostatic Neoplasms | 2002 |
Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer.
Topics: Aged; Aged, 80 and over; Androgen Antagonists; Anilides; Cross-Sectional Studies; Gonadotropin-Relea | 2005 |
Triiodothyronine modulates cell proliferation of human prostatic carcinoma cells by downregulation of the B-cell translocation gene 2.
Topics: Adenocarcinoma; Base Sequence; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Respo | 2008 |
Hormonal regulation of beta2-adrenergic receptor level in prostate cancer.
Topics: Adenocarcinoma; Androgen Antagonists; Androgens; Anilides; Antineoplastic Agents; Biopsy; Cell Line, | 2008 |
Acute infusion of hCG and thyroid hormone pattern before and after bilateral orchiectomy.
Topics: Aged; Castration; Chorionic Gonadotropin; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Hu | 1984 |
Pituitary-thyroid axis after bilateral orchiectomy in men.
Topics: Aged; Castration; Humans; Kinetics; Male; Middle Aged; Pituitary Gland; Prostatic Neoplasms; Thyroid | 1982 |
A serum-free defined medium capable of supporting growth of four established human prostatic carcinoma cell lines.
Topics: Adenocarcinoma; alpha-Fetoproteins; Cell Division; Clone Cells; Culture Media, Serum-Free; DNA, Neop | 1994 |
Triiodothyronine modulates growth, secretory function and androgen receptor concentration in the prostatic carcinoma cell line LNCaP.
Topics: Androgens; Cell Division; Cell Nucleus; Humans; Male; Metribolone; Prostate-Specific Antigen; Prosta | 1995 |
The deiodination of thyroxine to triiodothyronine in the testes of patients with prostate cancer.
Topics: Aged; Aged, 80 and over; Diethylstilbestrol; Humans; Iodide Peroxidase; Male; Middle Aged; Orchiecto | 1995 |
Retinoids stimulate lipid synthesis and accumulation in LNCaP prostatic adenocarcinoma cells.
Topics: Acetates; Adenocarcinoma; Azo Compounds; Calcitriol; Coloring Agents; Fatty Acid Synthases; Humans; | 1997 |
Interactive effects of triiodothyronine and androgens on prostate cell growth and gene expression.
Topics: Androgens; Blotting, Western; Cell Division; Drug Synergism; Enhancer Elements, Genetic; Gene Expres | 1999 |
Androgens decrease and retinoids increase the expression of insulin-like growth factor-binding protein-3 in LNcaP prostatic adenocarcinoma cells.
Topics: Adenocarcinoma; Calcitriol; Cell Division; Gene Expression Regulation; Gene Expression Regulation, N | 1999 |
Effects of hormones on SBP mRNA levels in human cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometri | 1991 |
Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones.
Topics: Blotting, Northern; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Estradiol; Female; Gene | 1989 |
Suppression of testicular androgenesis by D-tryptophan-6-luteinizing hormone-releasing hormone does not affect TSH secretion in male subjects.
Topics: Aged; Androgen Antagonists; Androgens; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Pr | 1986 |
[Study of prostatic carcinogenesis, using 20-methyl-cholanthrene in albino rats].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Animals; Carcinoma, Squamous Cell; Hormones; Male; Meth | 1968 |
[Hormonotherapy of so-called solid tumors].
Topics: Adrenal Cortex Hormones; Adult; Androgens; Bone Neoplasms; Breast Neoplasms; Castration; Diethylstil | 1972 |
Lack of significant binding of L-triiodothyronine by thyroxine-binding globulin in vivo as demonstrated by acute disappearance of 131-I-labeled triiodothyronine.
Topics: Adolescent; Adult; Aged; Epilepsy; Estrogens; Female; Hepatitis; Humans; Hyperthyroidism; Hypothyroi | 1966 |