triiodothyronine has been researched along with Cancer of Pancreas in 13 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A BALB/c nude mouse model bearing pancreatic cancer was established with human pancreatic cancer cell line Bx-PC3." | 1.39 | [Thyroid hormone inhibits the growth of pancreatic cancer xenograft in nude mice]. ( Dong, L; Jiang, J; Ma, H; Qin, B; Shang, B; Shi, H; Wang, N, 2013) |
| "Pancreatic cancer was induced by treatment with 40 mg/kg body wt N-nitrosobis-(2-oxopropyl)amine (BOP)." | 1.27 | Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice. ( Birt, DF; Bresnick, E; Pelling, JC; Pour, PM; Schweickert, L; Tibbels, MG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Strzałka, A | 1 |
| Hogendorf, P | 1 |
| Skulimowski, A | 1 |
| Spychalski, M | 1 |
| Strzelczyk, J | 1 |
| Durczynski, A | 1 |
| Rodríguez-Molinero, A | 1 |
| Hercbergs, A | 1 |
| Sarrias, M | 1 |
| Yuste, A | 1 |
| Wang, N | 1 |
| Shang, B | 1 |
| Shi, H | 1 |
| Ma, H | 1 |
| Jiang, J | 1 |
| Qin, B | 1 |
| Dong, L | 1 |
| Akiyama, S | 1 |
| Ogiwara, T | 1 |
| Aoki, T | 1 |
| Tsunekawa, K | 1 |
| Araki, O | 1 |
| Murakami, M | 1 |
| Verga Falzacappa, C | 3 |
| Patriarca, V | 2 |
| Bucci, B | 3 |
| Mangialardo, C | 1 |
| Michienzi, S | 2 |
| Moriggi, G | 1 |
| Stigliano, A | 2 |
| Brunetti, E | 3 |
| Toscano, V | 3 |
| Misiti, S | 3 |
| Goulart-Silva, F | 1 |
| Teixeira, Sda S | 1 |
| Luchessi, AD | 1 |
| Dos Santos, LR | 1 |
| Rebelato, E | 1 |
| Carpinelli, AR | 1 |
| Nunes, MT | 1 |
| Anastasi, E | 1 |
| Sciacchitano, S | 1 |
| Panacchia, L | 2 |
| Khouri, D | 1 |
| D'Acquarica, I | 1 |
| Di Mario, U | 1 |
| Perfetti, R | 1 |
| MacDonald, MJ | 1 |
| Moran, SM | 1 |
| Simonson, GD | 1 |
| Murai, H | 1 |
| Murakami, S | 1 |
| Ishida, K | 1 |
| Sugawara, M | 1 |
| Eriksson, M | 1 |
| Ajmani, SK | 1 |
| Mallette, LE | 1 |
| Rajatanavin, R | 1 |
| Liberman, C | 1 |
| Lawrence, GD | 1 |
| D'Arcangues, CM | 1 |
| Young, RA | 1 |
| Emerson, CH | 1 |
| Birt, DF | 1 |
| Pelling, JC | 1 |
| Pour, PM | 1 |
| Tibbels, MG | 1 |
| Schweickert, L | 1 |
| Bresnick, E | 1 |
13 other studies available for triiodothyronine and Cancer of Pancreas
| Article | Year |
|---|---|
Thyroid hormones concentration in portal and peripheral blood in patients with pancreatic cancer: Preliminary study.
Topics: Aged; Biomarkers, Tumor; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; | 2020 |
Plasma 3,3',5-Triiodo-L-thyronine [T3] level mirrors changes in tumor markers in two cases of metastatic cancer of the breast and pancreas treated with exogenous L-T3.
Topics: Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Humans; Neoplasm Metastasis; Pancreatic Neoplasm | 2018 |
[Thyroid hormone inhibits the growth of pancreatic cancer xenograft in nude mice].
Topics: Animals; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microvessels; Neovas | 2013 |
Glucagon-like peptide-1 stimulates type 3 iodothyronine deiodinase expression in a mouse insulinoma cell line.
Topics: Animals; Cell Line, Tumor; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Exenatide; G | 2014 |
The TRbeta1 is essential in mediating T3 action on Akt pathway in human pancreatic insulinoma cells.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Size; Cell Survival; Humans; Insulinoma; Pancreatic Neopl | 2009 |
Potential contribution of translational factors to triiodo-L-thyronine-induced insulin synthesis by pancreatic beta cells.
Topics: Animals; Carrier Proteins; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Dru | 2012 |
3,5,3'-Triiodo-L-thyronine enhances the differentiation of a human pancreatic duct cell line (hPANC-1) towards a beta-cell-Like phenotype.
Topics: Carcinoma, Pancreatic Ductal; Cell Differentiation; Cell Division; Cell Line, Tumor; Gene Expression | 2005 |
3,3',5-Triiodo-L-thyronine inhibits ductal pancreatic adenocarcinoma proliferation improving the cytotoxic effect of chemotherapy.
Topics: Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carcinoma, Pancr | 2007 |
The amino acid sequence of the pancreatic islet mitochondrial glycerol phosphate dehydrogenase is not unique and the enzyme is not thyroid or glucose responsive.
Topics: Amino Acid Sequence; Animals; Glucose; Glucosephosphate Dehydrogenase; Hyperthyroidism; In Vitro Tec | 1995 |
Elevated serum interleukin-6 and decreased thyroid hormone levels in postoperative patients and effects of IL-6 on thyroid cell function in vitro.
Topics: Aged; Cholecystectomy; Colorectal Neoplasms; Esophageal Neoplasms; Female; Humans; Interleukin-6; Ma | 1996 |
Hyperthyroidism from thyroid metastasis of pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Humans; Hyperthyroidism; Male; Middle Aged; Neoplasm Metastasis; Pancreatic Neoplasm | 1977 |
Euthyroid hyperthyroxinemia and thyroxine-binding prealbumin excess in islet cell carcinoma.
Topics: Adenoma, Islet Cell; Aged; Female; Humans; Male; Pancreatic Neoplasms; Prealbumin; Protein Binding; | 1985 |
Enhanced pancreatic and skin tumorigenesis in cabbage-fed hamsters and mice.
Topics: Animals; Body Weight; Brassica; Cricetinae; Dietary Fats; Female; Gallbladder Neoplasms; Male; Mesoc | 1987 |