Page last updated: 2024-11-08

triiodothyronine and Cancer of Ovary

triiodothyronine has been researched along with Cancer of Ovary in 14 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"There were 22 with an epithelial ovarian cancer (EOC), 15 with a borderline ovarian tumor, and 287 with benign disease."1.62Low serum T3 levels are associated with false-positive results when using the risk of ovarian malignancy algorithm (ROMA) in women with benign ovarian disease. ( Kim, MJ; Lee, DW; Lee, HN; Park, H; Shin, JE, 2021)
"Ovarian cancer is a highly metastatic disease."1.48The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer. ( Alfandari, A; Ashur-Fabian, O; Davis, PJ; Ellis, M; Hercbergs, A; Jenudi, Y; Moskovich, D; Tshuva, RY; Weingarten, C, 2018)
"Ovarian cancer is hormone-dependent, and epidemiological evidence links hyperthyroidism, inflammation of the ovarian surface, and increased risk of ovarian cancer."1.34Thyroid hormone signaling in human ovarian surface epithelial cells. ( Critchley, HO; Gubbay, O; Hillier, SG; Kostogiannou, A; Price, D; Rae, MT, 2007)
"A rare case of follicular adenoma arising from the thyroid tissue of a benign cystic teratoma of the left ovary was described in a 28-year-old, 13 weeks pregnant woman."1.26A follicular adenoma arising from the thyroid tissue of a benign cystic teratoma during pregnancy--lightmicroscopical, ultrastructural and endocrinological studies. ( Amino, N; Chiba, Y; Inoue, M; Kurachi, K; Matsumoto, K; Miyai, K; Tanaka, Y; Ueda, G; Yamasaki, M, 1980)
"Three cases of struma ovarii are reported, two of which were benign, and one which was malignant."1.26Benign and malignant struma ovarii. ( Burslem, RW; Hasleton, PS; Kelehan, P; Turner, L; Whittaker, JS, 1978)
"Mild hyperthyroidism is not a hazard to an otherwise normal pregnancy and does not require therapy on the basis of this presumption."1.25Thyroid disease in pregnancy. ( Prout, TE, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Heublein, S1
Jeschke, U1
Sattler, C1
Kuhn, C1
Hester, A1
Czogalla, B1
Trillsch, F1
Mahner, S1
Mayr, D1
Schmoeckel, E1
Ditsch, N1
Park, H1
Lee, DW1
Kim, MJ1
Shin, JE1
Lee, HN1
Shinderman-Maman, E2
Weingarten, C3
Moskovich, D2
Werner, H2
Hercbergs, A3
Davis, PJ3
Ellis, M3
Ashur-Fabian, O3
Jenudi, Y1
Tshuva, RY1
Alfandari, A1
Cohen, K1
Nabriski, D1
Twito, O1
Baraf, L1
Rae, MT1
Gubbay, O1
Kostogiannou, A1
Price, D1
Critchley, HO1
Hillier, SG1
Inoue, M1
Ueda, G1
Yamasaki, M1
Tanaka, Y1
Chiba, Y1
Kurachi, K1
Amino, N1
Miyai, K1
Matsumoto, K1
Doldi, N1
Taccagni, GL1
Bassan, M1
Frigerio, L1
Mangili, G1
Jansen, AM1
Ferrari, A1
Simkin, PH1
Ramirez, LA1
Zweizig, SL1
Afonso, SA1
Fraire, AE1
Khan, A1
Dunn, AD1
Dunn, JT1
Braverman, LE1
Suga, K1
Hirabayashi, A1
Motoyama, K1
Kume, N1
Matsunaga, N1
Tamura, H1
Kato, H1
Prout, TE1
Hasleton, PS1
Kelehan, P1
Whittaker, JS1
Burslem, RW1
Turner, L1
Yeh, EL1
Meade, RC1
Ruetz, PP1
Eckerström, S1

Reviews

1 review available for triiodothyronine and Cancer of Ovary

ArticleYear
[Hormone therapy in geriatrics].
    Lakartidningen, 1969, Jan-22, Volume: 66, Issue:4

    Topics: Adrenocorticotropic Hormone; Aged; Androgens; Arteriosclerosis; Breast Neoplasms; Coronary Disease;

1969

Other Studies

13 other studies available for triiodothyronine and Cancer of Ovary

ArticleYear
Subcellular Distribution of Thyroid Hormone Receptor Beta in Ovarian Cancer.
    International journal of molecular sciences, 2022, Feb-28, Volume: 23, Issue:5

    Topics: Cell Nucleus; Humans; Ovarian Neoplasms; Receptors, Thyroid Hormone; Thyroid Hormone Receptors beta;

2022
Low serum T3 levels are associated with false-positive results when using the risk of ovarian malignancy algorithm (ROMA) in women with benign ovarian disease.
    Taiwanese journal of obstetrics & gynecology, 2021, Volume: 60, Issue:1

    Topics: Adult; Algorithms; Biomarkers, Tumor; CA-125 Antigen; Carcinoma, Ovarian Epithelial; Early Detection

2021
Molecular insights into the transcriptional regulatory role of thyroid hormones in ovarian cancer.
    Molecular carcinogenesis, 2018, Volume: 57, Issue:1

    Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Down-Regulation; fas Receptor; Female; Gene Expressi

2018
The Interplay Between Epithelial-Mesenchymal Transition (EMT) and the Thyroid Hormones-αvβ3 Axis in Ovarian Cancer.
    Hormones & cancer, 2018, Volume: 9, Issue:1

    Topics: beta Catenin; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Gene Expressio

2018
The thyroid hormone-αvβ3 integrin axis in ovarian cancer: regulation of gene transcription and MAPK-dependent proliferation.
    Oncogene, 2016, Apr-14, Volume: 35, Issue:15

    Topics: Antibodies, Neutralizing; Cell Division; Cell Line, Tumor; Culture Media; Enzyme Activation; Extrace

2016
Thyroid hormone signaling in human ovarian surface epithelial cells.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:1

    Topics: Adult; Cells, Cultured; Epithelial Cells; Female; Gene Expression Regulation; Humans; Hyperthyroidis

2007
A follicular adenoma arising from the thyroid tissue of a benign cystic teratoma during pregnancy--lightmicroscopical, ultrastructural and endocrinological studies.
    Nihon Sanka Fujinka Gakkai zasshi, 1980, Volume: 32, Issue:7

    Topics: Adenoma; Adult; Female; Humans; Ovarian Neoplasms; Pregnancy; Pregnancy Complications; Teratoma; Thy

1980
Hashimoto's disease in a papillary carcinoma of the thyroid originating in a teratoma of the ovary (malignant struma ovarii).
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 1998, Volume: 12, Issue:1

    Topics: Autoantibodies; Carcinoma, Papillary; Female; Humans; Laparotomy; Microsomes; Middle Aged; Ovarian N

1998
Monomorphic teratoma of the ovary: a rare cause of triiodothyronine toxicosis.
    Thyroid : official journal of the American Thyroid Association, 1999, Volume: 9, Issue:9

    Topics: Aged; Female; Humans; Ovarian Neoplasms; Radionuclide Imaging; Struma Ovarii; Thyroglobulin; Thyroto

1999
Repeated 131I treatment of a residual ovarian teratoma containing malignant thyroid tissue.
    The British journal of radiology, 1999, Volume: 72, Issue:863

    Topics: Biomarkers, Tumor; CA-125 Antigen; Choristoma; Female; Humans; Iodine Radioisotopes; Middle Aged; Ne

1999
Thyroid disease in pregnancy.
    American journal of obstetrics and gynecology, 1975, Jul-01, Volume: 122, Issue:5

    Topics: Antithyroid Agents; Female; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn; Infant

1975
Benign and malignant struma ovarii.
    Archives of pathology & laboratory medicine, 1978, Volume: 102, Issue:4

    Topics: Aged; Female; Humans; Middle Aged; Neoplasm Metastasis; Ovarian Neoplasms; Ovary; Struma Ovarii; Thy

1978
Radionuclide study of struma ovarii.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1973, Volume: 14, Issue:2

    Topics: Female; Humans; Iodine Radioisotopes; Middle Aged; Ovarian Neoplasms; Radionuclide Imaging; Struma O

1973