triiodothyronine has been researched along with Cancer of Lung in 38 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with metastases of DTC, with insufficient uptake of I-131, received 6 weeks of treatment with 300 mg bexarotene/day." | 9.12 | Bexarotene increases uptake of radioiodide in metastases of differentiated thyroid carcinoma. ( Corssmit, EP; Liu, YY; Morreau, HA; Pereira, AM; Romijn, JA; Smit, JW; Stokkel, MP, 2006) |
| "Therapy with the retinoid X receptor agonist bexarotene is associated with hypothyroidism caused by decreased pituitary TSH secretion." | 9.12 | Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones. ( Pereira, AM; Romijn, JA; Smit, JW; Stokkel, MP; Visser, TJ, 2007) |
| "A comparative analysis of triiodothyronine (T3) and thyroxine (T4) distribution in organs and tissues of tumour-bearing and intact mice conducted wih 125J labelled T3 and T4 has shown considerable differences in the accumulation character of these hormones in mice with Lewis carcinoma and in intact animals in the liver, kidneys, lungs, adrenal glands, lymphatic nodes." | 7.67 | [Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma]. ( Dedenkov, AN; Norets, TA; Petrova, GA; Smoryzanova, OA; Vereshchagina, GV, 1985) |
| "Twelve patients with metastases of DTC, with insufficient uptake of I-131, received 6 weeks of treatment with 300 mg bexarotene/day." | 5.12 | Bexarotene increases uptake of radioiodide in metastases of differentiated thyroid carcinoma. ( Corssmit, EP; Liu, YY; Morreau, HA; Pereira, AM; Romijn, JA; Smit, JW; Stokkel, MP, 2006) |
| "Therapy with the retinoid X receptor agonist bexarotene is associated with hypothyroidism caused by decreased pituitary TSH secretion." | 5.12 | Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones. ( Pereira, AM; Romijn, JA; Smit, JW; Stokkel, MP; Visser, TJ, 2007) |
| "A comparative analysis of triiodothyronine (T3) and thyroxine (T4) distribution in organs and tissues of tumour-bearing and intact mice conducted wih 125J labelled T3 and T4 has shown considerable differences in the accumulation character of these hormones in mice with Lewis carcinoma and in intact animals in the liver, kidneys, lungs, adrenal glands, lymphatic nodes." | 3.67 | [Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma]. ( Dedenkov, AN; Norets, TA; Petrova, GA; Smoryzanova, OA; Vereshchagina, GV, 1985) |
| "Blocking the PD-1 pathway induces immune-related adverse events (irAEs) which often involve the thyroid gland (thyroid irAEs)." | 1.51 | Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab. ( Fujii, T; Hishizawa, M; Inagaki, N; Kawaguchi-Sakita, N; Kim, YH; Kitamura, M; Kitawaki, T; Matsumoto, S; Nomura, M; Otsuka, A; Saito, R; Sakamori, Y; Sone, M; Taura, D; Yamasaki, T; Yamauchi, I; Yasoda, A, 2019) |
| " Levothyroxine dosing required doubling in three patients with a known history of hypothyroidism." | 1.46 | Pembrolizumab-Induced Thyroiditis: Comprehensive Clinical Review and Insights Into Underlying Involved Mechanisms. ( Bornschlegl, S; Delivanis, DA; Dietz, AB; Gustafson, MP; Kottschade, L; Merten, MM; Ryder, M; Withers, S, 2017) |
| "Patients with type 2 diabetes (DM) demonstrate inadequate insulin release, elevated gluconeogenesis, and diminished nonoxidative glucose disposal." | 1.31 | Type 2 diabetic patients may have a mild form of an injury response: a clinical research center study. ( Richardson, AP; Tayek, JA, 2002) |
| "Nine patients with well-differentiated thyroid cancer aged 9-20 years were treated by thyroidectomy and subsequent irradiation with radioactive iodine." | 1.27 | Thyroid carcinoma in childhood. ( Anger, K; Feine, U, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (52.63) | 18.7374 |
| 1990's | 7 (18.42) | 18.2507 |
| 2000's | 4 (10.53) | 29.6817 |
| 2010's | 6 (15.79) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, Z | 1 |
| Song, P | 1 |
| Ji, D | 1 |
| Zheng, M | 1 |
| Qiu, G | 1 |
| Liu, Z | 1 |
| Wang, B | 1 |
| Kozlova, MB | 1 |
| Frantsiyants, EM | 1 |
| Trepitaki, LK | 1 |
| Kaplieva, IV | 1 |
| Pogorelova, YA | 1 |
| Sergostyants, GZ | 1 |
| Airapetova, TG | 1 |
| Chubaryan, AV | 1 |
| Yamauchi, I | 2 |
| Sakane, Y | 1 |
| Fukuda, Y | 1 |
| Fujii, T | 2 |
| Taura, D | 2 |
| Hirata, M | 1 |
| Hirota, K | 1 |
| Ueda, Y | 1 |
| Kanai, Y | 1 |
| Yamashita, Y | 1 |
| Kondo, E | 1 |
| Sone, M | 2 |
| Yasoda, A | 2 |
| Inagaki, N | 2 |
| Delivanis, DA | 1 |
| Gustafson, MP | 1 |
| Bornschlegl, S | 1 |
| Merten, MM | 1 |
| Kottschade, L | 1 |
| Withers, S | 1 |
| Dietz, AB | 1 |
| Ryder, M | 1 |
| Ansorge, C | 1 |
| Seufert, J | 1 |
| Meiss, F | 1 |
| von Bubnoff, D | 1 |
| Matsumoto, S | 1 |
| Sakamori, Y | 1 |
| Kim, YH | 1 |
| Nomura, M | 1 |
| Otsuka, A | 1 |
| Yamasaki, T | 1 |
| Saito, R | 1 |
| Kitamura, M | 1 |
| Kitawaki, T | 1 |
| Hishizawa, M | 1 |
| Kawaguchi-Sakita, N | 1 |
| Mazzoccoli, G | 1 |
| Pazienza, V | 1 |
| Piepoli, A | 1 |
| Muscarella, LA | 1 |
| Giuliani, F | 1 |
| Sothern, RB | 1 |
| Liu, YY | 1 |
| Stokkel, MP | 2 |
| Pereira, AM | 2 |
| Corssmit, EP | 1 |
| Morreau, HA | 1 |
| Romijn, JA | 2 |
| Smit, JW | 2 |
| Visser, TJ | 1 |
| Izotova, IA | 1 |
| Firsova, PP | 1 |
| Matveenko, EG | 1 |
| Svetukhina, ES | 1 |
| Bukhteeva, NF | 1 |
| Sapozhkova, LP | 1 |
| Maripova, ZM | 1 |
| Anger, K | 1 |
| Feine, U | 1 |
| Vereshchagina, GV | 5 |
| Axelrod, L | 1 |
| Halter, JB | 1 |
| Cooper, DS | 1 |
| Aoki, TT | 1 |
| Roussell, AM | 1 |
| Bagshaw, SL | 1 |
| Milmore, JE | 1 |
| Chandrasekaran, V | 1 |
| Weisburger, JH | 1 |
| Nakashima, T | 1 |
| Inoue, K | 1 |
| Shiro-ozu, A | 1 |
| Yoshinari, M | 1 |
| Okamura, K | 1 |
| Itoh, M | 1 |
| Nikol'skiĭ, VV | 1 |
| Chirvina, ED | 1 |
| Tiutiunova, AM | 1 |
| Fedenicheva, LN | 1 |
| Kharchenko, VP | 2 |
| Komarova, IN | 1 |
| Eigtved, A | 1 |
| Faber, J | 2 |
| Poulsen, S | 2 |
| Kirkegaard, C | 2 |
| Siersbaek-Nielsen, K | 1 |
| Friis, T | 1 |
| Mi, YY | 1 |
| Zhou, MZ | 1 |
| Xiu, X | 1 |
| Stepniak-Ziółkiewicz, I | 1 |
| Johansen, AH | 1 |
| Nielsen, BV | 1 |
| Marks, SL | 1 |
| Koblik, PD | 1 |
| Hornof, WJ | 1 |
| Feldman, EC | 1 |
| Kosuda, S | 1 |
| Arai, S | 1 |
| Hohshito, Y | 1 |
| Tokumitsu, H | 1 |
| Kusano, S | 1 |
| Kadota, T | 1 |
| Suzuki, K | 1 |
| Nakagawa, O | 1 |
| Aizawa, Y | 1 |
| Richardson, AP | 1 |
| Tayek, JA | 1 |
| Ratcliffe, JG | 1 |
| Stack, BH | 1 |
| Burt, RW | 1 |
| Radcliffe, WA | 1 |
| Spilg, WG | 1 |
| Cuthbert, J | 1 |
| Kennedy, RS | 1 |
| Losev, SI | 2 |
| Zubovskiĭ, GA | 1 |
| Ramaker, J | 1 |
| Wood, WG | 1 |
| Iversen, P | 1 |
| Zyrianov, BN | 1 |
| Velichko, SA | 1 |
| Kuznetsov, VV | 1 |
| Siianov, VS | 1 |
| Kiseleva, ES | 1 |
| Skorobogatov, NM | 1 |
| Zvekotkina, LS | 1 |
| Voronetskiĭ, IB | 1 |
| Dedenkov, AN | 1 |
| Petrova, GA | 1 |
| Smoryzanova, OA | 1 |
| Norets, TA | 1 |
| Taylor, S | 1 |
| Davis, PW | 1 |
| Adelberg, HM | 1 |
| Siemsen, JK | 1 |
| Jung, RC | 1 |
| Nicoloff, JT | 1 |
| Discala, VA | 1 |
| Kinney, MJ | 1 |
| Oyamada, H | 1 |
| Yui, N | 1 |
| Taketa, C | 1 |
| Ogata, T | 1 |
1 review available for triiodothyronine and Cancer of Lung
| Article | Year |
|---|---|
[Function of the hypothalamo-hypophyseal-thyroid axis in patients with pulmonary malignancies].
Topics: Female; Humans; Hypothalamo-Hypophyseal System; Lung Neoplasms; Male; Smoking; Thyroid Diseases; Thy | 1993 |
2 trials available for triiodothyronine and Cancer of Lung
| Article | Year |
|---|---|
Bexarotene increases uptake of radioiodide in metastases of differentiated thyroid carcinoma.
Topics: Adult; Aged; Bexarotene; Carcinoma, Papillary; Cell Differentiation; Female; Humans; Iodine Radioiso | 2006 |
Bexarotene-induced hypothyroidism: bexarotene stimulates the peripheral metabolism of thyroid hormones.
Topics: Aged; Anticarcinogenic Agents; Bexarotene; Drug Evaluation, Preclinical; Female; Humans; Hypothyroid | 2007 |
35 other studies available for triiodothyronine and Cancer of Lung
| Article | Year |
|---|---|
Thyroid hormones as biomarkers of lung cancer: a retrospective study.
Topics: Biomarkers; Female; Humans; Lung Neoplasms; Pregnancy; Prospective Studies; Retrospective Studies; T | 2023 |
Sex-Related Characteristics of Systemic Hormonal Homeostasis in Rats with Sarcoma C-45 Cells Transplanted to the Lung.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Female; Gene Expression; Hydrocortisone; Lung | 2017 |
Clinical Features of Nivolumab-Induced Thyroiditis: A Case Series Study.
Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Lung Neoplasm | 2017 |
Pembrolizumab-Induced Thyroiditis: Comprehensive Clinical Review and Insights Into Underlying Involved Mechanisms.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Autoantibo | 2017 |
Sequential occurrence of primary and secondary hypothyroidism during treatment with nivolumab: pitfalls in immuno-oncological therapy and endocrinological diagnostic procedures.
Topics: Adult; Antineoplastic Agents, Immunological; Autoimmune Hypophysitis; Humans; Hydrocortisone; Hypopi | 2018 |
Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab.
Topics: Aged; Antineoplastic Agents, Immunological; Carcinoma, Non-Small-Cell Lung; Female; Fluorodeoxygluco | 2019 |
Alteration of hypothalamic-pituitary-thyroid axis function in non-small-cell lung cancer patients.
Topics: Adult; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Circadian Rhythm; Female; Humans; Hypot | 2012 |
[The state of hormonal homeostasis in patients with lung cancer under combined and radiation treatment].
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Carcinoma; Carcinoma, Squamous Cell; Combined Mo | 1984 |
[Indicators of thyroid hormones and carcinoembryonic antigen in persons with a high risk of lung cancer].
Topics: Adult; Age Factors; Aged; Carcinoembryonic Antigen; Humans; Lung Diseases; Lung Neoplasms; Male; Mid | 1984 |
Thyroid carcinoma in childhood.
Topics: Adenocarcinoma; Adolescent; Adult; Carcinoma, Papillary; Child; Child, Preschool; Female; Humans; In | 1983 |
[Impaired tissue requirement for triiodothyronine in lung cancer].
Topics: Female; Humans; Lung Neoplasms; Male; Triiodothyronine | 1983 |
Hormone levels and fuel flow in patients with weight loss and lung cancer. Evidence for excessive metabolic expenditure and for an adaptive response mediated by a reduced level of 3,5,3'-triiodothyronine.
Topics: Adaptation, Physiological; Aged; Basal Metabolism; Blood Glucose; Body Weight; Catecholamines; Creat | 1983 |
Effects of hypothyroidism on development of nitrosomethylurea-induced tumors of the mammary gland, thyroid gland, and other tissues.
Topics: Animals; Female; Hypothyroidism; Kidney Neoplasms; Lung Neoplasms; Mammary Neoplasms, Experimental; | 1982 |
Predominant T3 synthesis in the metastatic thyroid carcinoma in a patient with T3-toxicosis.
Topics: Adenocarcinoma; Female; Humans; Hyperthyroidism; Lung Neoplasms; Middle Aged; Thyroglobulin; Thyroid | 1981 |
[Impaired synthesis of thyroid hormones in patients with lung cancer].
Topics: Humans; Lung Neoplasms; Male; Thyroid Gland; Thyroid Hormones; Thyroxine; Triiodothyronine | 1980 |
[Triiodothyronine, an anti-inflammatory factor in the early postoperative period in oncological patients].
Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Male; Middle Aged; Postoperative Complications; Postope | 1980 |
Nuclear 3,5,3'-triiodothyronine receptor binding in mononuclear blood cells from patients with malignant blood diseases and small cell carcinoma of the lung.
Topics: Carcinoma, Small Cell; Cell Nucleus; Humans; Leukemia; Lung Neoplasms; Monocytes; Receptors, Cell Su | 1993 |
[Study of relationship between TCM syndrome-types of malignant tumours and thyroid functional test].
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Diagnosis, Differential; Digestive System Neoplasm | 1995 |
[T3 thyrotoxicosis in a patient with a hormonally active, metastasizing follicular thyroid carcinoma].
Topics: Adenocarcinoma, Follicular; Female; Humans; Lung Neoplasms; Middle Aged; Thyroid Neoplasms; Thyrotox | 1994 |
99mTc-pertechnetate imaging of thyroid tumors in dogs: 29 cases (1980-1992).
Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma; Carcinoma, Medullary; Dog Diseases; Dogs; Female; Lung | 1994 |
[Successful TSH suppression therapy with triiodothyronine in a patient with pulmonary metastases from differentiated thyroid carcinoma in the absence of 131I uptake].
Topics: Adult; Carcinoma, Papillary; Female; Humans; Iodine Radioisotopes; Lung Neoplasms; Radiopharmaceutic | 1997 |
A case of pulmonary metastatic thyroid cancer complicated with Graves' disease.
Topics: Antithyroid Agents; Autoantibodies; Female; Graves Disease; Humans; Immunoglobulins, Thyroid-Stimula | 2001 |
Type 2 diabetic patients may have a mild form of an injury response: a clinical research center study.
Topics: Acute-Phase Reaction; Adult; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Fasti | 2002 |
Thyroid function in lung cancer.
Topics: Adrenal Cortex Hormones; Adult; Aged; Female; Humans; Lung Neoplasms; Male; Middle Aged; Thyroid Gla | 1978 |
[Endocrine system reaction in relation to the clinical manifestations of lung cancer].
Topics: Adenocarcinoma; Adult; Aged; Antigens; Carcinoma, Squamous Cell; Endocrine Glands; Female; Growth Ho | 1978 |
[Hormonal changes in patients with lung cancer].
Topics: Adult; Aged; Female; Growth Hormone; Humans; Hydrocortisone; Insulin; Lung Neoplasms; Male; Middle A | 1977 |
Transthyretin--an explanation of "anomalous" serum thyroid hormone values in severe illness?
Topics: Adult; Aged; Breast Neoplasms; Female; Gastrointestinal Neoplasms; Humans; Hyperthyroidism; Hypothyr | 1990 |
Thyroid hormone turnover in patients with small cell carcinoma of the lung.
Topics: Aged; Carcinoma, Small Cell; Female; Humans; Lung Neoplasms; Male; Middle Aged; Sex Hormone-Binding | 1988 |
[Main indicators of hormonal status in lung diseases].
Topics: Adrenocorticotropic Hormone; Calcitonin; Diagnosis, Differential; Growth Hormone; Humans; Hydrocorti | 1988 |
[Combined treatment of thyroid cancer metastases to the lungs in children and young people].
Topics: Adolescent; Adult; Child; Child, Preschool; Combined Modality Therapy; Humans; Iodine Radioisotopes; | 1987 |
[Distribution kinetics and metabolism of triiodothyronine and thyroxine in the organs and tissues of mice with transplanted Lewis carcinoma].
Topics: Animals; Carcinoma; Female; Kinetics; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Transplan | 1985 |
A review of the treatment of 222 patients with malignant tumours of the thyroid gland.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Bone Neoplasms; Carcinoma; Carcinoma, Papillary; Child; Fem | 1970 |
Scintigraphic detection of pulmonary bacterial infections with labeled thyroid hormones and pertechnetate.
Topics: Anti-Bacterial Agents; Humans; Iodine Radioisotopes; Lung Diseases; Lung Neoplasms; Male; Middle Age | 1971 |
Effects of myxedema on the renal diluting and concentrating mechanism.
Topics: Adult; Aged; Female; Glomerular Filtration Rate; Humans; Kidney Concentrating Ability; Kidney Functi | 1971 |
[Case of thyroid carcinoma showing an interesting clinical course].
Topics: Adenocarcinoma; Adult; Female; Humans; Iodine Isotopes; Lung Neoplasms; Lymphatic Metastasis; Method | 1969 |