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triiodothyronine and Cancer of Liver

triiodothyronine has been researched along with Cancer of Liver in 100 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"There have been reports of the use of levothyroxine or levothyroxine plus liothyronine for consumptive hypothyroidism caused by hepatic hemangiomas."7.85Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas. ( Hasegawa, Y; Higuchi, S; Takagi, M, 2017)
"The objective of this study was to determine the effects of sorafenib on TH levels in patients with hepatocellular carcinoma (HCC) and to evaluate possible mechanisms."7.85Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. ( Beukhof, CM; Bins, S; Chaker, L; de Herder, WW; de Rijke, YB; Mathijssen, RH; Peeters, RP; van Doorn, L; van Heerebeek, R; van Kemenade, FJ; Visser, TJ; Visser, WE, 2017)
" An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3)."7.76Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy. ( Dattani, MT; Langham, S; Mullis, PE; Peters, C, 2010)
"In consumptive hypothyroidism associated with infantile hepatic hemangiomas (IHH), elevated reverse triiodothyronine (rT3) is known due to elevated D3."4.12Advantages of monitoring rT3 and dividing LT3 dose in the treatment of consumptive hypothyroidism associated with infantile hepatic hemangioma. ( Igaki, J; Kina, Y; Koki, M; Matsuoka, T; Numazawa, M; Tomari, K, 2022)
"Consumptive hypothyroidism due to cutaneous hemangioma and hepatic hemangioendothelioma can be managed with propranolol and low-dose sirolimus."4.12Severe consumptive hypothyroidism in hepatic hemangioendothelioma. ( Dubinski, I; Häberle, B; Küppers, J; Lurz, E; Schmid, I; Schmidt, H; Walther, A, 2022)
"There have been reports of the use of levothyroxine or levothyroxine plus liothyronine for consumptive hypothyroidism caused by hepatic hemangiomas."3.85Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas. ( Hasegawa, Y; Higuchi, S; Takagi, M, 2017)
"The objective of this study was to determine the effects of sorafenib on TH levels in patients with hepatocellular carcinoma (HCC) and to evaluate possible mechanisms."3.85Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma. ( Beukhof, CM; Bins, S; Chaker, L; de Herder, WW; de Rijke, YB; Mathijssen, RH; Peeters, RP; van Doorn, L; van Heerebeek, R; van Kemenade, FJ; Visser, TJ; Visser, WE, 2017)
" An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3)."3.76Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy. ( Dattani, MT; Langham, S; Mullis, PE; Peters, C, 2010)
" We investigated the triiodothyronine (T3) modulation of gene expression, in human hepatocellular carcinoma cell lines, via a PCR-based cDNA subtraction method."3.72Regulation of fibronectin by thyroid hormone receptors. ( Chen, CY; Chen, SL; Huang, YH; Lin, KH; Shen, JJ; Shih, CH; Wang, CS; Yang, RC; Yen, CC, 2004)
" L-triiodothyronine and L-thyroxine stimulated hypoxia-induced Epo formation both in the kidney and in HepG2 cells in a dose-dependent fashion."3.69Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro. ( Fandrey, J; Frede, S; Jelkmann, W; Pagel, H; Wolff, M, 1994)
"We have studied the effects of triiodothyronine (T3) on the production of hepatic triacylglycerol lipase (HTGL) in the human hepatocellular carcinoma cell line, HepG2, by measuring its activity and mRNA levels."3.68Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells. ( Funahashi, T; Kubo, M; Matsuzawa, Y; Menju, M; Nozaki, S; Shimomura, I, 1992)
"Different rat and mouse models of hepatocarcinogenesis were investigated."1.56Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming. ( Bellomo, SE; Cabras, L; Columbano, A; Follenzi, A; Fornari, F; Giordano, S; Gramantieri, L; Kowalik, MA; Ledda-Columbano, GM; Merlin, S; Morandi, A; Orrù, C; Parri, M; Perra, A; Petrelli, A; Puliga, E; Rasola, A; Sanchez-Martin, C; Sebastian, C; Sulas, P, 2020)
"THs are involved in a crosstalk between hepatoma and stromal cells, and disruption of TH signaling is associated with tumorigenesis."1.56Thyroid hormones suppress FOXM1 expression to reduce liver cancer progression. ( Lin, KH; Wu, CH; Yeh, CT, 2020)
"The effects of miR-130b on hepatocellular carcinoma (HCC) invasion were further examined in vitro and in vivo."1.42Repression of microRNA-130b by thyroid hormone enhances cell motility. ( Chen, CY; Chen, WJ; Chi, HC; Chung, IH; Huang, YH; Liao, CJ; Lin, KH; Lin, TP; Lin, YH; Tsai, CY; Tsai, MM; Tseng, YH; Wu, MH; Wu, SM; Yeh, YH, 2015)
"Overexpression of miR-21 promoted hepatoma cell migration and invasion, similar to that observed with T(3) stimulation in hepatoma cells."1.39Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma. ( Chen, CY; Chi, HC; Huang, YH; Hung, YT; Liao, CH; Liao, CJ; Lin, CD; Lin, KH; Lin, SY; Lin, YH; Tsai, CY; Tseng, YH; Wang, CJ; Wu, SM, 2013)
"Triiodothyronine (T3) is a potent form of thyroid hormone mediates several physiological processes including cellular growth, development, and differentiation via binding to the nuclear thyroid hormone receptor (TR)."1.39Thyroid hormone receptor inhibits hepatoma cell migration through transcriptional activation of Dickkopf 4. ( Chen, CY; Chen, WJ; Chi, HC; Chung, IH; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lin, YH; Tsai, CY; Tseng, YH; Wu, SM; Wu, TI, 2013)
"We found that TR-overexpressing hepatoma cells treated with T(3) were apoptosis resistant, even when TRAIL was upregulated."1.38Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL. ( Chen, CY; Chen, SL; Chen, WJ; Chi, HC; Chung, IH; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lin, YH; Tsai, CY; Tsai, MM; Tseng, YH; Wu, SM; Yeh, CT, 2012)
"In addition, C/EBP was upregulated in hepatoma cells after T(3) treatment and ectopic expression of MAT1A inhibited cell migration and invasion in J7 hepatoma cells."1.36Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines. ( Chen, WJ; Cheng, WL; Chien, LF; Huang, YH; Liao, CH; Liao, CJ; Lin, KH; Lu, YH; Tsai, MM; Wu, SM; Yeh, CT, 2010)
"Liver hemangioendotheliomas are capable of producing an excess of the thyroid hormone inactivating enzyme, type-3 iodothyronine deiodinase."1.34Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation. ( Athanassaki, I; Balazs, AE; Gunn, SK; Haymond, MW; Huang, SA; Karaviti, LP; Tatevian, N, 2007)
"To examine the influence of T3 on hepatoma cell growth, thyroid receptor (TR)alpha1 or TRbeta1 over-expressing HepG2 cell lines were used."1.33Mediation of the inhibitory effect of thyroid hormone on proliferation of hepatoma cells by transforming growth factor-beta. ( Chen, WJ; Cheng, WL; Huang, YH; Liao, CJ; Liao, CY; Lin, KH; Yen, CC, 2006)
"Mutant TRs have been detected in human hepatocellular carcinoma cell lines and tissue, but their contribution to carcinogenesis has remained unclear."1.31Impaired interaction of mutant thyroid hormone receptors associated with human hepatocellular carcinoma with transcriptional coregulators. ( Chen, SL; Lin , KH; Wu , YH, 2001)
"Amiodarone and EMD 21388 were without effect both in cytosol and nuclear extract."1.29Drug competition for intracellular triiodothyronine-binding sites. ( Barlow, JW; Curtis, AJ; Loidl, NM; Raggatt, LE; Stockigt, JR; Topliss, DJ, 1994)
"Treatment of two acute promyelocytic leukemia patients with ATRA induced maximal 2."1.29An in vitro system for identifying agents capable of changing serum lipoprotein(a) concentration by regulating the transcriptional activity of the apolipoprotein(a) gene promoter. ( Azuma, H; Kanagawa, Y; Mima, N; Miyamoto, K; Saito, S; Shigekiyo, T; Shirakawa, M; Watanabe, A; Yamaguchi, H, 1996)
"5."1.28Diethylnitrosamine-induced increase in gamma-glutamyltranspeptidase in rat liver: its association with thyroid hormone deficiency and its reversal by tri-iodothyronine. ( Pulga, VB; Sulakhe, SJ; Tran, ST, 1992)
"Phloretin is an inhibitor of the mammalian glucose transporter and the iodothyronine-5'-deiodinase."1.28Phloretin inhibits cellular uptake and nuclear receptor binding of triiodothyronine in human hep G2 hepatocarcinoma cells. ( Movius, EG; Phyillaier, MM; Robbins, J, 1989)
"It was only found in hepatoma cells where it is regulated by estradiol, antiestrogen tamoxifen and triiodothyronine, in a similar way as secreted SBP."1.28Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones. ( Baulieu, EE; Baville, F; Bideux, G; Binart, N; Chambraud, B; Mercier-Bodard, C, 1989)
"It is postulated that this patient's hepatoma produced a substance stimulating thyroid-stimulating hormone synthesis and secretion with resultant inappropriate thyroid-stimulating hormone production and thyrotoxicosis."1.27Hepatocellular carcinoma: an unusual course with hyperthyroidism and inappropriate thyroid-stimulating hormone production. ( Helzberg, JH; Lukert, BP; McPhee, MS; Zarling, EJ, 1985)
"The human hepatoma-derived cell line, Hep G2, and a clone, H5A, isolated from Hep G2, were both found to secrete SBP-like protein."1.27Hormonal control of SBP in human hepatoma cells. ( Baulieu, EE; Mercier-Bodard, C, 1986)
"Similarly, the presence or absence of hepatic encephalopathy determined, and/or reflected, at least in part, the type of response observed."1.27Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease. ( Gavaler, JS; Sanghvi, A; Schade, RR; Tarter, R; Van Thiel, DH, 1986)
"Plasma T3 levels were reduced in both breast cancer group, but were reduced only in colonic cancer patients with systemic metastases."1.26Plasma thyronine levels in carcinoma of the breast and colon. ( Davis, TE; Rose, DP, 1981)

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199028 (28.00)18.7374
1990's25 (25.00)18.2507
2000's17 (17.00)29.6817
2010's26 (26.00)24.3611
2020's4 (4.00)2.80

Authors

AuthorsStudies
Numazawa, M1
Tomari, K1
Igaki, J1
Koki, M1
Kina, Y1
Matsuoka, T1
Walther, A1
Häberle, B1
Küppers, J1
Lurz, E1
Schmid, I1
Schmidt, H1
Dubinski, I1
Kowalik, MA1
Puliga, E1
Cabras, L1
Sulas, P1
Petrelli, A1
Perra, A1
Ledda-Columbano, GM1
Morandi, A1
Merlin, S1
Orrù, C1
Sanchez-Martin, C1
Fornari, F1
Gramantieri, L1
Parri, M1
Rasola, A1
Bellomo, SE1
Sebastian, C1
Follenzi, A1
Giordano, S1
Columbano, A1
Wu, CH1
Yeh, CT7
Lin, KH22
Higuchi, S1
Takagi, M1
Hasegawa, Y1
Chi, HC13
Chen, SL6
Lin, SL3
Tsai, CY11
Chuang, WY2
Lin, YH11
Huang, YH16
Tsai, MM9
Beukhof, CM1
van Doorn, L1
Visser, TJ1
Bins, S1
Visser, WE1
van Heerebeek, R1
van Kemenade, FJ1
de Rijke, YB1
de Herder, WW1
Chaker, L1
Mathijssen, RH1
Peeters, RP1
Pireddu, R1
Pibiri, M1
Valenti, D1
Sinico, C1
Fadda, AM1
Simbula, G1
Lai, F1
Liao, CH6
Liao, CJ10
Wu, SM11
Chen, CY11
Tseng, YH8
Lin, SY1
Hung, YT1
Wang, CJ1
Lin, CD2
Chung, IH5
Wu, TI1
Chen, WJ9
Cheng, WL5
Yeh, YH2
Huang, CY1
Chen, MH1
Yeh, YC1
Wu, MH3
Lin, TP1
Tai, PJ2
Srivastava, J1
Robertson, CL1
Gredler, R1
Siddiq, A1
Rajasekaran, D1
Akiel, MA1
Emdad, L1
Mas, V1
Mukhopadhyay, ND1
Fisher, PB1
Sarkar, D1
McAninch, EA1
Miller, BT1
Ueta, CB1
Jo, S1
Kim, BW1
Schmohl, KA1
Müller, AM1
Wechselberger, A1
Rühland, S1
Salb, N1
Schwenk, N1
Heuer, H1
Carlsen, J1
Göke, B1
Nelson, PJ1
Spitzweg, C1
Liu, H1
Yang, CC1
Tan, BC1
Sun, CP1
Lin, TK1
Chang, WC2
Chang, YT1
Stefos, GC1
Becker, W1
Lampidonis, AD1
Rogdakis, E1
Ritchie, JW1
Taylor, PM1
Yeh, SC1
Chen, RN2
Pai, LM1
Attia, RR1
Connnaughton, S1
Boone, LR1
Wang, F1
Elam, MB1
Ness, GC1
Cook, GA1
Park, EA2
Lu, YH1
Chien, LF1
Peters, C1
Langham, S1
Mullis, PE1
Dattani, MT1
Rosen, MD1
Chan, IH2
Privalsky, ML2
Gnoni, GV1
Rochira, A1
Leone, A1
Damiano, F1
Marsigliante, S1
Siculella, L1
Chi, LM1
Moriyama, K1
Tagami, T1
Akamizu, T1
Usui, T1
Saijo, M1
Kanamoto, N1
Hataya, Y1
Shimatsu, A1
Kuzuya, H1
Nakao, K1
Cassy, S1
Derouet, M1
Crochet, S1
Dridi, S1
Taouis, M1
Kawai, K1
Sasaki, S1
Morita, H1
Ito, T1
Suzuki, S1
Misawa, H1
Nakamura, H1
Yen, CC2
Shih, CH1
Shen, JJ1
Yang, RC1
Wang, CS1
Ho, J1
Kendrick, V1
Dewey, D1
Pacaud, D1
Liao, CY1
Hashimoto, K1
Yamada, M1
Matsumoto, S1
Monden, T1
Satoh, T1
Mori, M1
Ventura-Holman, T1
Mamoon, A1
Maher, JF1
Subauste, JS1
Balazs, AE1
Athanassaki, I1
Gunn, SK1
Tatevian, N1
Huang, SA1
Haymond, MW1
Karaviti, LP1
Otto, T1
Fandrey, J4
Stora, C2
Aussel, C2
Lafaurie, M2
Formento, JL2
Ordóñez-Llanos, J1
Rodríguez-Espinosa, J1
Gómez-Gerique, JA1
Teras, LE1
Kildema, LA1
Birk, RV1
Rose, DP1
Davis, TE1
Sorimachi, K3
Yasumura, Y1
Castelli, D1
Djordjević, PB1
Stajić, MS1
Jovanović, P1
Sinadinović, J1
Pagel, H1
Frede, S1
Wolff, M1
Jelkmann, W3
Kobayashi, M2
Horiuchi, R2
Crowe, TC2
Cowen, NL2
Loidl, NM3
Topliss, DJ4
Stockigt, JR4
Barlow, JW4
Vandenbrouck, Y1
Janvier, B1
Loriette, C1
Bereziat, G1
Mangeney-Andreani, M1
Kragie, L2
Forrester, ML1
Cody, V1
McCourt, M1
Brenner, B1
Raggatt, LE3
Blok, RB2
Curtis, AJ1
Lin, YW1
Lee, HF1
Liu, WL1
Chen, ST3
Chang, KS1
Cheng, SY3
Nakamura, N1
Shidoji, Y1
Moriwaki, H1
Muto, Y1
Scholz, GH1
Zhu, XG2
Shieh, HY2
Hsu, HC2
McPhie, P2
Azuma, H1
Yamaguchi, H1
Mima, N1
Shirakawa, M1
Miyamoto, K1
Kanagawa, Y1
Watanabe, A1
Shigekiyo, T1
Saito, S1
Stephan, ZF1
Yurachek, EC1
Sharif, R1
Wasvary, JM1
Leonards, KS1
Hu, CW1
Hintze, TH1
Steele, RE1
Bakker, O1
Hudig, F1
Meijssen, S1
Wiersinga, WM1
Guglielmi, R1
Pacella, CM1
Dottorini, ME1
Bizzarri, GC1
Todino, V1
Crescenzi, A1
Rinaldi, R1
Panunzi, C1
Rossi, Z1
Colombo, L1
Papini, E1
Kondo, T1
Katoh, R1
Omata, K1
Oyama, T1
Yagawa, A1
Kawaoi, A1
Lin , KH1
Wu , YH1
Benvenga, S1
Lakshmanan, M1
Trimarchi, F1
Mason, KP1
Koka, BV1
Eldredge, EA1
Fishman, SJ1
Burrows, PE1
Cahnmann, HJ1
Robbins, J2
Carella, C1
Del Vecchio-Blanco, C1
Pisano, G1
Biscaglia, G1
Caporaso, N1
Theriault, A1
Ogbonna, G1
Adeli, K1
Nozaki, S1
Shimomura, I1
Funahashi, T1
Menju, M1
Kubo, M1
Matsuzawa, Y1
Sulakhe, SJ1
Pulga, VB1
Tran, ST1
Giralt, M1
Gurney, AL1
Liu, JS1
Hakimi, P1
Hanson, RW1
Mercier-Bodard, C3
Nivet, V1
Baulieu, EE3
Darby, IA1
Bouhnik, J1
Coezy, ED1
Corvol, P1
Seydel, FP1
Siegers, CP1
Matsuda, M1
Nagai, K1
Okano, Y1
Tanabashi, S1
Kametani, M1
Tokimitsu, N1
Sakata, S1
Miura, K1
Conti, R1
Ceccarini, C1
Tecce, MF1
Movius, EG1
Phyillaier, MM1
Ober, KP1
Lowder, SC1
Baville, F1
Bideux, G1
Binart, N1
Chambraud, B1
Hachisu, T1
Takikawa, H1
Chou, CK1
Ho, LT1
Ting, LP1
Hu, CP1
Su, TS1
Suen, CS1
Huang, MY1
Chang, CM1
Helzberg, JH1
McPhee, MS1
Zarling, EJ1
Lukert, BP1
Murata, Y1
Sarne, DH1
Horwitz, AL1
Lecocq, R1
Aden, DP1
Knowles, BB1
Refetoff, S1
Van Thiel, DH1
Tarter, R1
Gavaler, JS1
Schade, RR1
Sanghvi, A1
Ichikawa, K1
DeGroot, LJ1
Estadella, MD1
Pujol, MJ1
Domingo, J1
Jemec, B1
Hamada, S1
Nakagawa, T1
Mori, T1
Torizuka, K1
Hunt, SM1
Osnos, M1
Rivlin, RS1
Karsten, U1
Sydow, G1
Wollenberger, A1
Graffi, A1
Fisher, ER1
Fisher, B1

Reviews

1 review available for triiodothyronine and Cancer of Liver

ArticleYear
Thyroid hormone actions in liver cancer.
    Cellular and molecular life sciences : CMLS, 2013, Volume: 70, Issue:11

    Topics: Carcinoma, Hepatocellular; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Models,

2013

Other Studies

99 other studies available for triiodothyronine and Cancer of Liver

ArticleYear
Advantages of monitoring rT3 and dividing LT3 dose in the treatment of consumptive hypothyroidism associated with infantile hepatic hemangioma.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Nov-25, Volume: 35, Issue:11

    Topics: Hemangioma; Humans; Hypothyroidism; Liver Neoplasms; Male; Thyroxine; Triiodothyronine; Triiodothyro

2022
Severe consumptive hypothyroidism in hepatic hemangioendothelioma.
    Journal of pediatric endocrinology & metabolism : JPEM, 2022, Dec-16, Volume: 35, Issue:12

    Topics: Hemangioendothelioma; Humans; Hypothyroidism; Infant; Liver Neoplasms; Male; Propranolol; Sirolimus;

2022
Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming.
    Journal of hepatology, 2020, Volume: 72, Issue:6

    Topics: Aged; Animals; Anticarcinogenic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Cell Differentiat

2020
Thyroid hormones suppress FOXM1 expression to reduce liver cancer progression.
    Oncology reports, 2020, Volume: 44, Issue:4

    Topics: Carcinoma, Hepatocellular; Cell Proliferation; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Disea

2020
Use of liothyronine without levothyroxine in the treatment of mild consumptive hypothyroidism caused by hepatic hemangiomas.
    Endocrine journal, 2017, Jun-29, Volume: 64, Issue:6

    Topics: Hemangioma; Hormone Replacement Therapy; Humans; Hypothyroidism; Infant; Liver; Liver Neoplasms; Mal

2017
Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover.
    Oncogene, 2017, 09-14, Volume: 36, Issue:37

    Topics: Animals; Carcinogenesis; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Hepatocytes; Humans; L

2017
Sorafenib-Induced Changes in Thyroid Hormone Levels in Patients Treated for Hepatocellular Carcinoma.
    The Journal of clinical endocrinology and metabolism, 2017, 08-01, Volume: 102, Issue:8

    Topics: Aged; Amino Acid Transport Systems, Neutral; Animals; Antineoplastic Agents; Carcinoma, Hepatocellul

2017
A novel lactoferrin-modified stealth liposome for hepatoma-delivery of triiodothyronine.
    International journal of pharmaceutics, 2018, Feb-15, Volume: 537, Issue:1-2

    Topics: Animals; Asialoglycoprotein Receptor; Carcinoma, Hepatocellular; Cell Line, Tumor; Delayed-Action Pr

2018
Thyroid hormone regulation of miR-21 enhances migration and invasion of hepatoma.
    Cancer research, 2013, Apr-15, Volume: 73, Issue:8

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Gene Ex

2013
Thyroid hormone receptor inhibits hepatoma cell migration through transcriptional activation of Dickkopf 4.
    Biochemical and biophysical research communications, 2013, Sep-13, Volume: 439, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Movement; Disease Progression; Humans; Intercellular Signal

2013
Negative modulation of the epigenetic regulator, UHRF1, by thyroid hormone receptors suppresses liver cancer cell growth.
    International journal of cancer, 2015, Jul-01, Volume: 137, Issue:1

    Topics: Animals; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cell Proliferation; Gene Expression Regu

2015
Repression of microRNA-130b by thyroid hormone enhances cell motility.
    Journal of hepatology, 2015, Volume: 62, Issue:6

    Topics: Aged; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Disease Progression; Down-Regulati

2015
Thyroid hormone-mediated regulation of lipocalin 2 through the Met/FAK pathway in liver cancer.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: Acute-Phase Proteins; Animals; Blotting, Western; Cell Line, Tumor; Cell Movement; Focal Adhesion Ki

2015
Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC).
    The Journal of biological chemistry, 2015, Jun-19, Volume: 290, Issue:25

    Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line, Tumor; Down-Regulation; Euth

2015
Thyroid Hormone at Near Physiologic Concentrations Acutely Increases Oxygen Consumption and Extracellular Acidification in LH86 Hepatoma Cells.
    Endocrinology, 2015, Volume: 156, Issue:11

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Homeostasis; Humans; Hypothyroidism; Liver; Liver Neopl

2015
Thyroid hormones and tetrac: new regulators of tumour stroma formation via integrin αvβ3.
    Endocrine-related cancer, 2015, Volume: 22, Issue:6

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentia

2015
ChIP-on-chip analysis of thyroid hormone-regulated genes and their physiological significance.
    Oncotarget, 2016, Apr-19, Volume: 7, Issue:16

    Topics: Carcinoma, Hepatocellular; Chromatin Immunoprecipitation; Gene Expression Regulation, Neoplastic; He

2016
Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy.
    Autophagy, 2016, Volume: 12, Issue:12

    Topics: Animals; Autophagy; Carcinogenesis; Carcinoma, Hepatocellular; Death-Associated Protein Kinases; Die

2016
Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinoma.
    Scientific reports, 2016, 12-09, Volume: 6

    Topics: Carcinoma, Hepatocellular; Cell Division; Gene Knockdown Techniques; Hep G2 Cells; Humans; Liver Neo

2016
Cloning and functional characterization of the ovine malic enzyme promoter.
    Gene, 2009, Jan-01, Volume: 428, Issue:1-2

    Topics: Adipose Tissue; Animals; Base Sequence; Carcinoma, Hepatocellular; Cells, Cultured; Cloning, Molecul

2009
Tryptophan and iodothyronine transport interactions in HepG2 human hepatoma cells.
    Amino acids, 2010, Volume: 38, Issue:5

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Primers; Humans; Liver Neoplasms; Tr

2010
Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion.
    Endocrine-related cancer, 2010, Volume: 17, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Cells, Cultured; Extracellular

2010
Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha).
    The Journal of biological chemistry, 2010, Jan-22, Volume: 285, Issue:4

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; Hepatocytes; Humans; Hyperthyro

2010
Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines.
    Cellular and molecular life sciences : CMLS, 2010, Volume: 67, Issue:11

    Topics: Base Sequence; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Cell Mo

2010
Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy.
    Hormone research in paediatrics, 2010, Volume: 74, Issue:2

    Topics: Hemangioma; Humans; Hypothyroidism; Infant; Iodide Peroxidase; Liver Neoplasms; Male; Thyroxine; Tri

2010
Mutant thyroid hormone receptors (TRs) isolated from distinct cancer types display distinct target gene specificities: a unique regulatory repertoire associated with two renal clear cell carcinomas.
    Molecular endocrinology (Baltimore, Md.), 2011, Volume: 25, Issue:8

    Topics: Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Gene Expression Profiling; Gene Expression Regulat

2011
3,5,3'triiodo-L-thyronine induces SREBP-1 expression by non-genomic actions in human HEP G2 cells.
    Journal of cellular physiology, 2012, Volume: 227, Issue:6

    Topics: Carcinoma, Hepatocellular; Feedback, Physiological; Hep G2 Cells; Humans; Integrin alphaVbeta3; Live

2012
Stable isotope labeling with amino acids in cell culture (SILAC)-based quantitative proteomics study of a thyroid hormone-regulated secretome in human hepatoma cells.
    Molecular & cellular proteomics : MCP, 2012, Volume: 11, Issue:4

    Topics: Amino Acids; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement;

2012
Thyroid hormone receptors promote metastasis of human hepatoma cells via regulation of TRAIL.
    Cell death and differentiation, 2012, Volume: 19, Issue:11

    Topics: Animals; Apoptosis; bcl-X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Hep G2 Cells; Humans

2012
Thyroid hormone suppresses cell proliferation through endoglin-mediated promotion of p21 stability.
    Oncogene, 2013, Aug-15, Volume: 32, Issue:33

    Topics: Antigens, CD; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatin Immunopreci

2013
Thyroid hormone action is disrupted by bisphenol A as an antagonist.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Animals; Benzhydryl Compounds; Cell Nucleus; DNA-Binding Proteins; Gene Expression; Glycoprotein Hor

2002
Leptin and insulin downregulate leptin receptor gene expression in chicken-derived leghorn male hepatoma cells.
    Poultry science, 2003, Volume: 82, Issue:10

    Topics: Animals; Blotting, Western; Carcinoma, Hepatocellular; Dexamethasone; Gene Expression Regulation; In

2003
Unliganded thyroid hormone receptor-beta1 represses liver X receptor alpha/oxysterol-dependent transactivation.
    Endocrinology, 2004, Volume: 145, Issue:12

    Topics: Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Dimerization;

2004
Regulation of fibronectin by thyroid hormone receptors.
    Journal of molecular endocrinology, 2004, Volume: 33, Issue:2

    Topics: Carcinoma, Hepatocellular; Cycloheximide; DNA-Binding Proteins; Enzyme Inhibitors; Fibronectins; Gen

2004
New insight into the pathophysiology of severe hypothyroidism in an infant with multiple hepatic hemangiomas.
    Journal of pediatric endocrinology & metabolism : JPEM, 2005, Volume: 18, Issue:5

    Topics: Female; Hemangioma; Humans; Hypothyroidism; Infant; Infant, Newborn; Liver Neoplasms; Severity of Il

2005
Thyroid hormone receptors mutated in liver cancer function as distorted antimorphs.
    Oncogene, 2006, Jun-15, Volume: 25, Issue:25

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cloning, Molecular; DNA-Binding Proteins; Electrophoret

2006
Mediation of the inhibitory effect of thyroid hormone on proliferation of hepatoma cells by transforming growth factor-beta.
    Journal of molecular endocrinology, 2006, Volume: 36, Issue:1

    Topics: Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferati

2006
Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone.
    Endocrinology, 2006, Volume: 147, Issue:9

    Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Chlorocebus aethiops

2006
Thyroid hormone responsive genes in the murine hepatocyte cell line AML 12.
    Gene, 2007, Jul-15, Volume: 396, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cholesterol; DNA, Complementary; Ge

2007
Rapid resolution of consumptive hypothyroidism in a child with hepatic hemangioendothelioma following liver transplantation.
    Annals of clinical and laboratory science, 2007,Summer, Volume: 37, Issue:3

    Topics: Female; Hemangioendothelioma; Humans; Hypothyroidism; Infant; Liver Neoplasms; Liver Transplantation

2007
Thyroid hormone induces hypoxia-inducible factor 1alpha gene expression through thyroid hormone receptor beta/retinoid x receptor alpha-dependent activation of hepatic leukemia factor.
    Endocrinology, 2008, Volume: 149, Issue:5

    Topics: Active Transport, Cell Nucleus; Basic-Leucine Zipper Transcription Factors; Binding Sites; Carcinoma

2008
Thyroid hormone receptors suppress pituitary tumor transforming gene 1 activity in hepatoma.
    Cancer research, 2008, Mar-15, Volume: 68, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Cell Growth Processes; Cell Line, Tumor; Down-Regulation; Gene E

2008
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide.
    Journal of cancer research and clinical oncology, 1981, Volume: 100, Issue:1

    Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Female; Liver Neoplasms; Neoplasms, Experimental

1981
Antibody binding serum T3 in a patient with hepatocarcinoma.
    Journal of endocrinological investigation, 1984, Volume: 7, Issue:2

    Topics: Aged; Carcinoma, Hepatocellular; Humans; Immunoglobulins; Liver Neoplasms; Male; Protein Binding; Ra

1984
Alterations in carbohydrate metabolizing enzymes induced by hormones during the process of carcinogenesis.
    IARC scientific publications, 1983, Issue:51

    Topics: Animals; Carbohydrate Metabolism; Cell Transformation, Neoplastic; Diethylnitrosamine; Glucosephosph

1983
Plasma thyronine levels in carcinoma of the breast and colon.
    Archives of internal medicine, 1981, Volume: 141, Issue:9

    Topics: Adult; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Middle Aged;

1981
High affinity of triiodothyronine (T3) for nonphenolic ring deiodinase and high affinity of tetraiodothyroacetic acid (TETRAC) for phenolic ring deiodinase in cultured monkey hepatocarcinoma cells and in rat liver homogenates.
    Endocrinologia japonica, 1981, Volume: 28, Issue:6

    Topics: Animals; Cell Line; Chromatography, Ion Exchange; Haplorhini; Iodide Peroxidase; Liver; Liver Neopla

1981
Thyroid activity during hepatocarcinogenesis by N-2-fluorenylacetamide in the male rat.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 36, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Liver Neoplasms; Male; Neoplasms, Experimental; Pituitary Gland; Rat

1982
[Levels of the thyroid hormones, triiodothyronine and tetraiodothyronine, in the blood in liver diseases].
    Srpski arhiv za celokupno lekarstvo, 1981, Volume: 109, Issue:7

    Topics: Humans; Liver Diseases; Liver Neoplasms; Thyroxine; Triiodothyronine

1981
Thyroid hormones enhance hypoxia-induced erythropoietin production in vitro.
    Experimental hematology, 1994, Volume: 22, Issue:3

    Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cells, Cultured; DNA; Dose-Response Relation

1994
Actions of 3,5,3'-tri-iodothyronine on the synthesis and secretion of major plasma proteins by a human hepatoblastoma cell line (Hep G2).
    Journal of molecular endocrinology, 1995, Volume: 14, Issue:2

    Topics: Acute-Phase Proteins; Carcinoma, Hepatocellular; Culture Media, Serum-Free; Electrophoresis, Gel, Tw

1995
Down-regulation of thyroxine-binding globulin messenger ribonucleic acid by 3,5,3'-triiodothyronine in human hepatoblastoma cells.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:7

    Topics: Cell Line; Gene Expression Regulation, Neoplastic; Hepatoblastoma; Humans; Kinetics; Liver Neoplasms

1995
The modulation of apolipoprotein E gene expression by 3,3'-5-triiodothyronine in HepG2 cells occurs at transcriptional and post-transcriptional levels.
    European journal of biochemistry, 1994, Sep-01, Volume: 224, Issue:2

    Topics: Apolipoproteins E; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cyclohexi

1994
Computer-assisted molecular modeling of benzodiazepine and thyromimetic inhibitors of the HepG2 iodothyronine membrane transporter.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:3

    Topics: Benzodiazepines; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Humans; Image Proce

1994
Serum immunoreactive erythropoietin in hyper- and hypothyroidism: clinical observations related to cell culture studies.
    European journal of haematology, 1994, Volume: 53, Issue:1

    Topics: Carcinoma, Hepatocellular; Erythropoietin; Hemoglobins; Humans; Hyperthyroidism; Hypothyroidism; Liv

1994
Stimulation of sex hormone-binding globulin mRNA and attenuation of corticosteroid-binding globulin mRNA by triiodothyronine in human hepatoma cells.
    European journal of endocrinology, 1994, Volume: 130, Issue:2

    Topics: Carcinoma, Hepatocellular; Culture Media, Conditioned; Culture Media, Serum-Free; Cycloheximide; Dos

1994
Drug competition for intracellular triiodothyronine-binding sites.
    European journal of endocrinology, 1994, Volume: 130, Issue:4

    Topics: Amiodarone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; C

1994
Increased invasive activity of human hepatocellular carcinoma cells is associated with an overexpression of thyroid hormone beta 1 nuclear receptor and low expression of the anti-metastatic nm23 gene.
    Cancer letters, 1995, Nov-27, Volume: 98, Issue:1

    Topics: Carcinoma, Hepatocellular; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Liver Ne

1995
Apoptosis in human hepatoma cell line induced by 4,5-didehydro geranylgeranoic acid (acyclic retinoid) via down-regulation of transforming growth factor-alpha.
    Biochemical and biophysical research communications, 1996, Feb-06, Volume: 219, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Cells, Cultured; Epidermal

1996
Preferential inhibition of cytoplasmic T3 binding is associated with reduced nuclear binding in cultured cells.
    Thyroid : official journal of the American Thyroid Association, 1996, Volume: 6, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Nucleus; Cells, Cultured; Cytoplasm; Diclofenac; Hepat

1996
Identification of naturally occurring dominant negative mutants of thyroid hormone alpha 1 and beta 1 receptors in a human hepatocellular carcinoma cell line.
    Endocrinology, 1996, Volume: 137, Issue:10

    Topics: Carcinoma, Hepatocellular; DNA; Genes, Dominant; Humans; Liver Neoplasms; Point Mutation; Promoter R

1996
An in vitro system for identifying agents capable of changing serum lipoprotein(a) concentration by regulating the transcriptional activity of the apolipoprotein(a) gene promoter.
    Biochemical and biophysical research communications, 1996, Oct-14, Volume: 227, Issue:2

    Topics: Adult; Apolipoproteins; Apoprotein(a); Base Sequence; Cell Line; Danazol; DNA; DNA Primers; Female;

1996
Demonstration of potent lipid-lowering activity by a thyromimetic agent devoid of cardiovascular and thermogenic effects.
    Atherosclerosis, 1996, Sep-27, Volume: 126, Issue:1

    Topics: Animals; Animals, Newborn; Anticholesteremic Agents; Binding, Competitive; Body Temperature; Carcino

1996
Dominant negative activity of mutant thyroid hormone alpha1 receptors from patients with hepatocellular carcinoma.
    Endocrinology, 1997, Volume: 138, Issue:12

    Topics: Base Sequence; Carcinoma, Hepatocellular; Cloning, Molecular; DNA-Binding Proteins; Genes, Dominant;

1997
Effects of triiodothyronine and amiodarone on the promoter of the human LDL receptor gene.
    Biochemical and biophysical research communications, 1998, Aug-19, Volume: 249, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Hepatocellular; Gene Expression; Humans; Liver Neopla

1998
Severe thyrotoxicosis due to hyperfunctioning liver metastasis from follicular carcinoma: treatment with (131)I and interstitial laser ablation.
    Thyroid : official journal of the American Thyroid Association, 1999, Volume: 9, Issue:2

    Topics: Adenoma; Biopsy, Needle; Female; Humans; Iodine Radioisotopes; Laser Therapy; Liver; Liver Neoplasms

1999
Incidentally detected liver metastasis of well-differentiated follicular carcinoma of the thyroid, mimicking ectopic thyroid.
    Pathology international, 2000, Volume: 50, Issue:6

    Topics: Adenocarcinoma, Follicular; Cell Differentiation; Choristoma; Diagnosis, Differential; Female; Human

2000
Impaired interaction of mutant thyroid hormone receptors associated with human hepatocellular carcinoma with transcriptional coregulators.
    Endocrinology, 2001, Volume: 142, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; COS Cells; DNA; DNA-Binding Proteins; Gene Silencing; Genes, Dom

2001
Carnitine is a naturally occurring inhibitor of thyroid hormone nuclear uptake.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:12

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Carnitine; Cell Line

2000
Perioperative considerations in a hypothyroid infant with hepatic haemangioma.
    Paediatric anaesthesia, 2001, Volume: 11, Issue:2

    Topics: Anesthesia, General; Congenital Hypothyroidism; Decompression, Surgical; Embolization, Therapeutic;

2001
Formation and metabolism of 3',5'-diiodothyronine and 3,5-diiodothyronine by cultured monkey hepatocarcinoma cells.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:3

    Topics: Animals; Cell Line; Diiodothyronines; Haplorhini; Liver Neoplasms; Thyronines; Thyroxine; Triiodothy

1979
Metabolism of thyroid hormones by cultured monkey hepatocarcinoma cells. Nonphenolic ring dieodination and sulfation.
    The Journal of biological chemistry, 1977, Jul-10, Volume: 252, Issue:13

    Topics: Carcinoma, Hepatocellular; Cell Line; Chromatography, Ion Exchange; Chromatography, Thin Layer; Hydr

1977
[Reverse T3 (rT3), T3 and T4 in chronic aggressive hepatitis, cirrhosis and hepatic neoplasms].
    Bollettino della Societa italiana di biologia sperimentale, 1978, Mar-30, Volume: 54, Issue:6

    Topics: Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Neoplasms; Thyroxine; Triiodothyronine; T

1978
Thyroid hormone modulates apolipoprotein B gene expression in HepG2 cells.
    Biochemical and biophysical research communications, 1992, Jul-31, Volume: 186, Issue:2

    Topics: Apolipoproteins B; Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; DNA Probes; Gene Expres

1992
Stimulation of the activity and mRNA level of hepatic triacylglycerol lipase by triiodothyronine in HepG2 cells.
    Biochimica et biophysica acta, 1992, Aug-19, Volume: 1127, Issue:3

    Topics: Blotting, Northern; Carcinoma, Hepatocellular; Cell Line; Dose-Response Relationship, Drug; Heparin;

1992
Requisite structural characteristics for benzodiazepine inhibition of triiodothyronine uptake into a human liver cell line.
    Life sciences, 1992, Volume: 51, Issue:9

    Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Hu

1992
Diethylnitrosamine-induced increase in gamma-glutamyltranspeptidase in rat liver: its association with thyroid hormone deficiency and its reversal by tri-iodothyronine.
    The International journal of biochemistry, 1992, Volume: 24, Issue:4

    Topics: Aging; Animals; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Male; Precanc

1992
Identification of a thyroid hormone response element in the phosphoenolpyruvate carboxykinase (GTP) gene. Evidence for synergistic interaction between thyroid hormone and cAMP cis-regulatory elements.
    The Journal of biological chemistry, 1991, Nov-15, Volume: 266, Issue:32

    Topics: Base Sequence; Binding Sites; Carcinoma, Hepatocellular; Cell Line; Chromosome Deletion; Cyclic AMP;

1991
Effects of hormones on SBP mRNA levels in human cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1991, Volume: 40, Issue:4-6

    Topics: Blotting, Northern; Breast Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cycloheximide; Endometri

1991
Thyroid hormone receptors and stimulation of angiotensinogen production in HepG2 cells.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1991, Volume: 27, Issue:1

    Topics: Angiotensinogen; Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Humans; K

1991
Role of cytochrome P450 in the control of the production of erythropoietin.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: Carcinoma, Hepatocellular; Cobalt; Cysteamine; Cytochrome P-450 Enzyme System; Ditiocarb; Erythropoi

1990
[A case of primary hepatocellular carcinoma associated with hyperthyroxine-binding-globulinemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1986, Volume: 75, Issue:11

    Topics: alpha-Fetoproteins; Alpha-Globulins; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Mid

1986
Thyroid hormone effect on alpha-fetoprotein and albumin coordinate expression by a human hepatoma cell line.
    Biochimica et biophysica acta, 1989, Aug-14, Volume: 1008, Issue:3

    Topics: Albumins; alpha-Fetoproteins; Blotting, Northern; Carcinoma, Hepatocellular; Electrophoresis, Polyac

1989
Phloretin inhibits cellular uptake and nuclear receptor binding of triiodothyronine in human hep G2 hepatocarcinoma cells.
    Endocrinology, 1989, Volume: 124, Issue:4

    Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Gluco

1989
Massive hyperthyroxinemia in a euthyroid patient with hepatocellular carcinoma.
    The American journal of medicine, 1989, Volume: 86, Issue:5

    Topics: Aged; Carcinoma, Hepatocellular; Female; Humans; Hyperthyroxinemia; Liver Neoplasms; Triiodothyronin

1989
Regulation of SBP synthesis in human cancer cell lines by steroid and thyroid hormones.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: Blotting, Northern; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line; Estradiol; Female; Gene

1989
Dualistic effects of thyroid hormone on a human hepatoma cell line: inhibition of thyroxine-binding globulin synthesis and stimulation of alpha 1-acid glycoprotein synthesis.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Humans; Kinetics; Liver Neoplasms; Orosomucoid;

1988
Selective suppression of insulin-induced proliferation of cultured human hepatoma cells by somatostatin.
    The Journal of clinical investigation, 1987, Volume: 79, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Division; Cell Line; Dose-Response Relationship, Drug; Humans; Insul

1987
Hepatocellular carcinoma: an unusual course with hyperthyroidism and inappropriate thyroid-stimulating hormone production.
    Gastroenterology, 1985, Volume: 88, Issue:1 Pt 1

    Topics: Carcinoma, Hepatocellular; Female; Humans; Hyperthyroidism; Liver Neoplasms; Middle Aged; Paraneopla

1985
Characterization of thyroxine-binding globulin secreted by a human hepatoma cell line.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:3

    Topics: Carcinoma, Hepatocellular; Cell Line; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Humans;

1985
Hormonal control of SBP in human hepatoma cells.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line; Dexamethasone; Dihydrotestosterone; Dose-Response Relationship

1986
Thyroid and pituitary hormone responses to TRH in advanced nonalcoholic liver disease.
    Journal of endocrinological investigation, 1986, Volume: 9, Issue:6

    Topics: Carcinoma, Hepatocellular; Growth Hormone; Hepatic Encephalopathy; Humans; Liver Diseases; Liver Neo

1986
Thyroid hormone receptors in a human hepatoma cell line: multiple receptor forms on isoelectric focusing.
    Molecular and cellular endocrinology, 1987, Volume: 51, Issue:1-2

    Topics: Binding, Competitive; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Hot Temperature; Humans; H

1987
Proliferative response of putative preneoplastic hepatocytes to triiodothyronine, aminoacids, glucagon and heparine.
    Cell biology international reports, 1988, Volume: 12, Issue:3

    Topics: Amino Acids; Animals; Cell Division; Diethylnitrosamine; Glucagon; Heparin; Hyperplasia; Liver Neopl

1988
Studies of the goitrogenic and oncogenic effect of methylthiouracil in C3H mice.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1971, Volume: 79, Issue:6

    Topics: Adenoma; Animals; Antithyroid Agents; Carcinogens; Carcinoma, Hepatocellular; Cysts; Female; Glucose

1971
Re-evaluation of thyroxine binding and free thyroxine in human serum by paper electrophoresis and equilibrium dialysis, and a new free thyroxine index.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:2

    Topics: Anorexia Nervosa; Carcinoma, Hepatocellular; Diabetes Mellitus; Dialysis; Electrophoresis; Female; G

1970
Thyroid hormone regulation of mitochondrial alpha-glycerophosphate dehydrogenase in liver and hepatoma.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Enzyme Induction; Glycerolphosphate Dehydrogenase; Liver Neoplas

1970
Rat liver glycerolphosphate dehydrogenases: activity changes and induction by thyroid hormone of the mitochondrial enzyme in hepatomas and in precancerous and growing liver.
    Acta biologica et medica Germanica, 1971, Volume: 26, Issue:6

    Topics: Animals; Carcinoma, Hepatocellular; Cytoplasm; Enzyme Induction; Female; Glycerolphosphate Dehydroge

1971
Experimental studies of factors influencing development of hepatic metastases. XVII. Role of thyroid.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Female; Hypothyroidism; Liver Neoplasms;

1966