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triiodothyronine and Cancer of Head

triiodothyronine has been researched along with Cancer of Head in 17 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Thyroid function was measured by means of thyroid stimulating hormone (TSH), free thyroxine (FT4) and free triiodthyronine (FT3) in 43 patients who had nonthyroid head-neck carcinomas treated by radiotherapy or radiotherapy in combination with other modalities."3.80Hypothyroidism after radiotherapy of head and neck cancer. ( Bernát, L; Hrušák, D, 2014)
"To determine the dose-response relationship of the thyroid for radiation-induced hypothyroidism in head-and-neck radiation therapy, according to 6 normal tissue complication probability models, and to find the best-fit parameters of the models."1.39Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy. ( Bakhshandeh, M; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A; Vasheghani, M, 2013)
"Radiation-induced thyroiditis is regarded as primary damage to the thyroid gland."1.38Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography. ( Bakhshandeh, M; Edraki, HR; Hashemi, B; Kazemnejad, A; Mahdavi, SR; Nikoofar, A, 2012)
"Hypothyroidism is recognized as a common complication of treatment in patients with head and neck carcinoma (HNC) and is reported in up to 75% of patients who receive combined treatment."1.31Pretreatment prevalence of hypothyroidism in patients with head and neck carcinoma. ( Bedrin, L; Dori, S; Horowitz, Z; Kronenberg, J; Mini, S; Peleg, M; Shoshani, Y; Taicher, S; Talmi, YP; Wolf, M, 2001)
"transplanted parathyroid adenoma secreted parathyroid hormone (PTH) in the SCID mice for more than 1 year."1.30Morphology and function of human benign tumors and normal thyroid tissues maintained in severe combined immunodeficient mice. ( Fukuda, K; Hande, PM; Hongyo, T; Kubo, T; Kurooka, M; Li, LY; Mori, K; Nakajima, H; Nomura, T; Sutoh, K; Taniguchi, E; Wang, H, 1998)
"Triiodothyronine (T3) was directly correlated in the cancer patients with non-oxidative glucose utilization at the two physiological insulin concentrations (r = 0."1.29Reduced non-oxidative glucose utilization in cancer patients is associated with a low triiodothyronine concentration. ( Tayek, JA, 1995)
"The mean thyroid dose for irradiated malignant lymphomas in the prospective and the retrospective group was 45 Gy and 43 Gy respectively."1.28Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis. ( Becker, W; Feyerabend, T; Kapp, B; Reiners, C; Richter, E, 1990)
"Eleven patients with head and neck cancer (ten men, one woman; mean age, 65 years) (larynx, six; oropharynx, two; tongue, one; skin, one; thyroid, one) with regional lymph node enlargements either in contiguity or firmly adherent to the vascular structures of the neck have been treated by means of external microwaves (915, 434 MHz) applicators."1.28Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis. ( Airoldi, M; Brossa, PC; D'Alberto, M; Gabriele, P; Pedani, F; Ragona, R; Tseroni, V, 1990)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's4 (23.53)18.2507
2000's3 (17.65)29.6817
2010's4 (23.53)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Gülses, A1
Wagner, J1
Torst, P1
Wieker, H1
Schulte, DM1
Spille, DC1
Wiltfang, J1
Spille, J1
Haas, M1
Lein, A1
Fuereder, T1
Schnoell, J1
Brkic, FF1
Campion, NJ1
Liu, DT1
Kadletz-Wanke, L1
Heiduschka, G1
Jank, BJ1
Bernát, L1
Hrušák, D1
Bölling, T1
Geisenheiser, A1
Pape, H1
Martini, C1
Rübe, C1
Timmermann, B1
Fischedick, K1
Kortmann, RD1
Gerss, J1
Koch, R1
Willich, N1
Bakhshandeh, M2
Hashemi, B2
Mahdavi, SR2
Nikoofar, A2
Edraki, HR1
Kazemnejad, A2
Vasheghani, M1
Koc, M1
Unuvar, N1
Sen, RC1
Capoglu, I1
Sen, M1
Alterio, D1
Jereczek-Fossa, BA1
Franchi, B1
D'Onofrio, A1
Piazzi, V1
Rondi, E1
Ciocca, M1
Gibelli, B1
Grosso, E1
Tradati, N1
Mariani, L1
Boboc, GI1
Orecchia, R1
Holten, I1
Tayek, JA1
Fukuda, K1
Nakajima, H1
Taniguchi, E1
Sutoh, K1
Wang, H1
Hande, PM1
Li, LY1
Kurooka, M1
Mori, K1
Hongyo, T1
Kubo, T1
Nomura, T1
Mini, S1
Dori, S1
Horowitz, Z1
Bedrin, L1
Peleg, M1
Wolf, M1
Shoshani, Y1
Taicher, S1
Kronenberg, J1
Talmi, YP1
Feyerabend, T1
Kapp, B1
Richter, E1
Becker, W1
Reiners, C1
Airoldi, M1
Gabriele, P1
Brossa, PC1
Pedani, F1
Tseroni, V1
D'Alberto, M1
Ragona, R1
Razack, MS1
Shimaoka, K1
Sako, K1
Rao, U1
Glatstein, E1
McHardy-Young, S1
Brast, N1
Eltringham, JR1
Kriss, JP1
Hales, I1
Reeve, T1
Johnson, D1

Trials

1 trial available for triiodothyronine and Cancer of Head

ArticleYear
Suppressive therapy of thyroid nodules in patients with previous radiotherapy to the head and neck.
    American journal of surgery, 1988, Volume: 156, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neopla

1988

Other Studies

16 other studies available for triiodothyronine and Cancer of Head

ArticleYear
Changes in hormones of the thyroid axis after tracheostomy and their influence on regeneration in patients with head and neck cancer: A prospective study.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2022, Volume: 50, Issue:12

    Topics: Aged; Head and Neck Neoplasms; Humans; Prospective Studies; Regeneration; Thyroid Gland; Thyrotropin

2022
Low free triiodothyronine and immune-related hyperthyroidism are associated with overall and progression-free survival in head and neck squamous cell carcinoma treated with pembrolizumab.
    International immunopharmacology, 2023, Volume: 123

    Topics: Antibodies, Monoclonal, Humanized; Carcinoma; Head and Neck Neoplasms; Humans; Hyperthyroidism; Prog

2023
Hypothyroidism after radiotherapy of head and neck cancer.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2014, Volume: 42, Issue:4

    Topics: Aged; Carcinoma; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Female; Follow-Up Studies;

2014
Hypothyroidism after head-and-neck radiotherapy in children and adolescents: preliminary results of the "Registry for the Evaluation of Side Effects After Radiotherapy in Childhood and Adolescence" (RiSK).
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Cranial Irradiation; Germany; Head and Neck Neoplasms; Hormone

2011
Evaluation of thyroid disorders during head-and-neck radiotherapy by using functional analysis and ultrasonography.
    International journal of radiation oncology, biology, physics, 2012, May-01, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Arteries; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged

2012
Normal tissue complication probability modeling of radiation-induced hypothyroidism after head-and-neck radiation therapy.
    International journal of radiation oncology, biology, physics, 2013, Feb-01, Volume: 85, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Confidence Intervals; Dose-Response Relationship, Radiation; Female;

2013
A prospective evaluation of early thyroid dysfunction on completion of neck radiotherapy.
    Oral oncology, 2003, Volume: 39, Issue:6

    Topics: Adult; Aged; Case-Control Studies; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neck

2003
Thyroid disorders in patients treated with radiotherapy for head-and-neck cancer: a retrospective analysis of seventy-three patients.
    International journal of radiation oncology, biology, physics, 2007, Jan-01, Volume: 67, Issue:1

    Topics: Adult; Aged; Biomarkers; Dose-Response Relationship, Radiation; Female; Head and Neck Neoplasms; Hum

2007
Acute response of the thyroid to external radiation.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Supplement, 1983, Volume: 283

    Topics: Adult; Aged; Animals; Autoantibodies; Biopsy, Needle; Cell Nucleus; Cytoplasm; Female; Follow-Up Stu

1983
Reduced non-oxidative glucose utilization in cancer patients is associated with a low triiodothyronine concentration.
    Journal of the American College of Nutrition, 1995, Volume: 14, Issue:4

    Topics: Blood Glucose; Calorimetry, Indirect; Carcinoma, Squamous Cell; Female; Glucose; Glucose Clamp Techn

1995
Morphology and function of human benign tumors and normal thyroid tissues maintained in severe combined immunodeficient mice.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adenoma; Animals; Female; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Male; Mice; Mice, S

1998
Pretreatment prevalence of hypothyroidism in patients with head and neck carcinoma.
    Cancer, 2001, Sep-15, Volume: 92, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; H

2001
Incidence of hypothyroidism after irradiation of the neck with special reference to lymphoma patients. A retrospective and prospective analysis.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Child; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Hypothyr

1990
Serum thyroid hormone changes in head and neck cancer patients treated with microwave hyperthermia on lymph node metastasis.
    Cancer, 1990, Feb-15, Volume: 65, Issue:4

    Topics: Aged; Aged, 80 and over; Carcinoma; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Human

1990
Alterations in serum thyrotropin (TSH) and thyroid function following radiotherapy in patients with malignant lymphoma.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:6

    Topics: Adolescent; Adult; Female; Head and Neck Neoplasms; Hodgkin Disease; Humans; Hypothyroidism; Ion Exc

1971
Managment of functioning thyroid cancer.
    The Medical journal of Australia, 1969, Feb-22, Volume: 1, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Biopsy; Digestive System; Female; Head and Neck Neoplasms; Hospitalizat

1969