triiodothyronine has been researched along with Cancer of Colon in 14 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Plasma triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were measured in 44 early breast cancer patients, 48 with advanced breast cancer, 20 with cancer of the colon, and 56 healthy women of similar age." | 7.66 | Plasma triiodothyronine concentrations in breast cancer. ( Davis, TE; Rose, DP, 1979) |
| "Plasma triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were measured in 44 early breast cancer patients, 48 with advanced breast cancer, 20 with cancer of the colon, and 56 healthy women of similar age." | 3.66 | Plasma triiodothyronine concentrations in breast cancer. ( Davis, TE; Rose, DP, 1979) |
| "In a colon cancer model, vaccination with T3-stimulated and tumor antigen-loaded DCs inhibited tumor growth in wild type mice, an effect that was eliminated in IL-17-deficient animals." | 1.72 | Triiodothyronine-stimulated dendritic cell vaccination boosts antitumor immunity against murine colon cancer. ( Alejandra Alamino, V; Carolina Donadio, A; Cecilia Sánchez, M; Del Carmen Bravo-Miana, R; Del Mar Montesinos, M; Florencia Soler, M; Gabriela Pellizas, C; María Negretti-Borga, D; Subirada, P, 2022) |
| "We measured D3 expression in 6 colon cancer cell lines and human tumors and correlated it with the activity of the β-catenin/TCF complex." | 1.38 | β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells. ( Ambrosio, R; Casillo, A; Dentice, M; Fenzi, G; Iaccarino, A; Larsen, PR; Luongo, C; Salvatore, D; Sibilio, A; Troncone, G, 2012) |
| "Cyclin D1 is an oncogenic cyclin frequently over-expressed in cancer." | 1.32 | Beta-catenin/Tcf-1-mediated transactivation of cyclin D1 promoter is negatively regulated by thyroid hormone. ( Kashiwabara, Y; Kitagawa, M; Masuda, H; Matsushita, A; Misawa, H; Nagayama, K; Nakamura, H; Nakano, K; Natsume, H; Nishiyama, K; Sasaki, S, 2003) |
| "Plasma T3 levels were reduced in both breast cancer group, but were reduced only in colonic cancer patients with systemic metastases." | 1.26 | Plasma thyronine levels in carcinoma of the breast and colon. ( Davis, TE; Rose, DP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (42.86) | 18.7374 |
| 1990's | 5 (35.71) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Florencia Soler, M | 1 |
| Del Carmen Bravo-Miana, R | 1 |
| María Negretti-Borga, D | 1 |
| Subirada, P | 1 |
| Alejandra Alamino, V | 1 |
| Cecilia Sánchez, M | 1 |
| Carolina Donadio, A | 1 |
| Gabriela Pellizas, C | 1 |
| Del Mar Montesinos, M | 1 |
| Dentice, M | 1 |
| Luongo, C | 1 |
| Ambrosio, R | 1 |
| Sibilio, A | 1 |
| Casillo, A | 1 |
| Iaccarino, A | 1 |
| Troncone, G | 1 |
| Fenzi, G | 1 |
| Larsen, PR | 1 |
| Salvatore, D | 1 |
| Natsume, H | 1 |
| Sasaki, S | 1 |
| Kitagawa, M | 1 |
| Kashiwabara, Y | 1 |
| Matsushita, A | 1 |
| Nakano, K | 1 |
| Nishiyama, K | 1 |
| Nagayama, K | 1 |
| Misawa, H | 1 |
| Masuda, H | 1 |
| Nakamura, H | 1 |
| Rose, DP | 2 |
| Davis, TE | 2 |
| Jumarie, C | 1 |
| Malo, C | 1 |
| Feng, J | 1 |
| Orlowski, J | 1 |
| Lingrel, JB | 1 |
| Rognoni, JB | 1 |
| Pichard, V | 1 |
| Honore, S | 1 |
| Rigot, V | 1 |
| Lehmann, M | 1 |
| Roccabianca, M | 1 |
| Carles, G | 1 |
| Luis, J | 1 |
| Marvaldi, J | 1 |
| Briand, C | 1 |
| Turner, JG | 1 |
| Brownlie, BE | 1 |
| Sadler, WA | 1 |
| Olsen, EG | 1 |
| Symons, C | 1 |
| Hawkey, C | 1 |
| Arango, A | 1 |
| Lester, JL | 1 |
| Martinez, OV | 1 |
| Malinin, TI | 1 |
| Zeppa, R | 1 |
| Iishi, H | 1 |
| Tatsuta, M | 1 |
| Baba, M | 1 |
| Okuda, S | 1 |
| Taniguchi, H | 1 |
| Zirvi, KA | 1 |
| Lee, JK | 1 |
| Gordon, PR | 1 |
| Stall, GM | 1 |
| Gilchrest, BA | 1 |
| Kaplan, MM | 1 |
14 other studies available for triiodothyronine and Cancer of Colon
| Article | Year |
|---|---|
Triiodothyronine-stimulated dendritic cell vaccination boosts antitumor immunity against murine colon cancer.
Topics: Animals; Cancer Vaccines; Colonic Neoplasms; Dendritic Cells; Humans; Interleukin-12; Interleukin-17 | 2022 |
β-Catenin regulates deiodinase levels and thyroid hormone signaling in colon cancer cells.
Topics: Adenoma; Animals; beta Catenin; Caco-2 Cells; Cadherins; Carcinoma; Cell Differentiation; Cell Proli | 2012 |
Beta-catenin/Tcf-1-mediated transactivation of cyclin D1 promoter is negatively regulated by thyroid hormone.
Topics: beta Catenin; Cells, Cultured; Colonic Neoplasms; Cyclin D1; Cytoskeletal Proteins; DNA-Binding Prot | 2003 |
Plasma thyronine levels in carcinoma of the breast and colon.
Topics: Adult; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Humans; Liver Neoplasms; Middle Aged; | 1981 |
Alkaline phosphatase and peptidase activities in Caco-2 cells: differential response to triiodothyronine.
Topics: Adenocarcinoma; Alkaline Phosphatase; Cell Communication; Cell Division; Colonic Neoplasms; Culture | 1994 |
Identification of a functional thyroid hormone response element in the upstream flanking region of the human Na,K-ATPase beta 1 gene.
Topics: Adenocarcinoma; Animals; Base Sequence; Cell Nucleus; Coleoptera; Colonic Neoplasms; DNA; DNA, Neopl | 1993 |
Convergent effects of growth factors, hormones, and fibronectin are necessary for the enterocyte differentiation of a colon adenocarcinoma cell line (HT29-D4).
Topics: Adenocarcinoma; Animals; Cattle; Cell Differentiation; Cell Division; Colonic Neoplasms; Culture Med | 1998 |
Letter: Does T4 toxicosis exist?
Topics: Colonic Neoplasms; Female; Humans; Hyperthyroidism; Middle Aged; Neoplasm Metastasis; Thyroid Functi | 1975 |
Effect of triac on the developing heart.
Topics: Animals; Animals, Newborn; Cardiomegaly; Colonic Neoplasms; Ethanolamines; Female; Fetus; Heart; Inj | 1977 |
Bacteriologic and systemic effects of intraoperative segmental bowel preparation with povidone iodine.
Topics: Adult; Aged; Bacteria; Carcinoma; Colon; Colonic Diseases; Colonic Neoplasms; Humans; Iodine; Middle | 1979 |
Plasma triiodothyronine concentrations in breast cancer.
Topics: Adult; Age Factors; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Humans; Middle Aged; Thyroid | 1979 |
Enhancement by thyroxine of experimental carcinogenesis induced in rat colon by azoxymethane.
Topics: Adenocarcinoma; Adenoma; Analysis of Variance; Animals; Azoxymethane; Body Weight; Carcinogens; Colo | 1992 |
Development of serum-free media for the growth of human gastrointestinal adenocarcinoma xenografts as primary tissue cultures.
Topics: Adenocarcinoma; alpha-Fetoproteins; Cell Division; Cell Line; Colonic Neoplasms; Culture Media, Seru | 1991 |
Phenolic and tyrosyl ring iodothyronine deiodination by the Caco-2 human colon carcinoma cell line.
Topics: Carcinoma; Cell Differentiation; Colonic Neoplasms; Humans; Intestinal Absorption; Iodine; Kinetics; | 1989 |