triiodothyronine has been researched along with Brain Injuries in 20 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chorea resolved with treatment of hyperthyroidism." | 1.27 | Hyperthyroid chorea in an elderly woman associated with sole elevation of T3. ( Ahronheim, JC, 1988) |
| "Prolonged coma afterhead trauma is associated with depletion of 3', 5' cyclic adenosine monophosphate (cAMP) in the cerebrospinal fluid (CSF)." | 1.26 | Hypothalamic hypothyroidism and hypogonadism in prolonged traumatic coma. ( Fleischer, AS; Payne, NS; Rudman, DR; Tindall, GT, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 3 (15.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Donangelo, I | 1 |
| Abe, K | 1 |
| Scremin, O | 1 |
| Ke, S | 1 |
| Li, F | 1 |
| Milanesi, A | 1 |
| Liu, YY | 1 |
| Brent, GA | 1 |
| Mori, Y | 1 |
| Tomonaga, D | 1 |
| Kalashnikova, A | 1 |
| Furuya, F | 1 |
| Akimoto, N | 1 |
| Ifuku, M | 1 |
| Okuno, Y | 1 |
| Beppu, K | 1 |
| Fujita, K | 1 |
| Katafuchi, T | 1 |
| Shimura, H | 1 |
| Churilov, LP | 1 |
| Noda, M | 1 |
| Srinivas, R | 1 |
| Brown, SD | 1 |
| Chang, YF | 1 |
| Garcia-Fillion, P | 1 |
| Adelson, PD | 1 |
| Chourdakis, M | 1 |
| Kraus, MM | 1 |
| Tzellos, T | 1 |
| Sardeli, C | 1 |
| Peftoulidou, M | 1 |
| Vassilakos, D | 1 |
| Kouvelas, D | 1 |
| Crupi, R | 1 |
| Paterniti, I | 1 |
| Campolo, M | 1 |
| Di Paola, R | 1 |
| Cuzzocrea, S | 1 |
| Esposito, E | 1 |
| Meissner, W | 1 |
| Krapp, C | 1 |
| Kauf, E | 1 |
| Dohrn, B | 1 |
| Reinhart, K | 1 |
| Vasil'eva, EM | 1 |
| Shor, TA | 1 |
| Poddubnaia, AE | 1 |
| Schneider, HJ | 2 |
| Schneider, M | 2 |
| Saller, B | 2 |
| Petersenn, S | 1 |
| Uhr, M | 1 |
| Husemann, B | 1 |
| von Rosen, F | 2 |
| Stalla, GK | 2 |
| Tanriverdi, F | 1 |
| Ulutabanca, H | 1 |
| Unluhizarci, K | 1 |
| Selcuklu, A | 1 |
| Casanueva, FF | 1 |
| Kelestimur, F | 1 |
| Yassouridis, A | 1 |
| Barberá, M | 1 |
| Belda, FJ | 1 |
| Maruenda, A | 1 |
| Badenes, R | 1 |
| Frasquet, FJ | 1 |
| Chulia, V | 1 |
| Pinna, G | 1 |
| Meinhold, H | 1 |
| Hiedra, L | 1 |
| Thoma, R | 1 |
| Hoell, T | 1 |
| Gräf, KJ | 1 |
| Stoltenburg-Didinger, G | 1 |
| Eravci, M | 1 |
| Prengel, H | 1 |
| Brödel, O | 1 |
| Finke, R | 1 |
| Baumgartner, A | 1 |
| Fleischer, AS | 1 |
| Rudman, DR | 1 |
| Payne, NS | 1 |
| Tindall, GT | 1 |
| Heinicke, E | 1 |
| Gottardis, M | 1 |
| Nigitsch, C | 1 |
| Schmutzhard, E | 1 |
| Neumann, M | 1 |
| Putensen, C | 1 |
| Hackl, JM | 1 |
| Koller, W | 1 |
| Ziegler, MG | 1 |
| Morrissey, EC | 1 |
| Marshall, LF | 1 |
| Zhou, XP | 1 |
| Ahronheim, JC | 1 |
| Shutov, AA | 1 |
| Chudinov, AA | 1 |
2 trials available for triiodothyronine and Brain Injuries
| Article | Year |
|---|---|
Effect of early compared with delayed enteral nutrition on endocrine function in patients with traumatic brain injury: an open-labeled randomized trial.
Topics: Adolescent; Adult; Aged; APACHE; Brain Injuries; Endocrine System; Enteral Nutrition; Female; Humans | 2012 |
Thyroid hormone response to moderate hypothermia in severe brain injury.
Topics: Adult; Brain Injuries; Female; Humans; Hypothermia, Induced; Intensive Care Units; Male; Prospective | 2003 |
18 other studies available for triiodothyronine and Brain Injuries
| Article | Year |
|---|---|
Thyroid hormone treatment activates protective pathways in both in vivo and in vitro models of neuronal injury.
Topics: Animals; Apoptosis; Basic Helix-Loop-Helix Transcription Factors; Brain Edema; Brain Injuries; Cell | 2017 |
Effects of 3,3',5-triiodothyronine on microglial functions.
Topics: Adenosine Triphosphate; Adjuvants, Pharmaceutic; Animals; Brain Injuries; Cell Movement; Cells, Cult | 2015 |
Endocrine function in children acutely following severe traumatic brain injury.
Topics: Adolescent; Adrenocorticotropic Hormone; Brain Injuries; Child; Child, Preschool; Endocrine System; | 2010 |
Exogenous T3 administration provides neuroprotection in a murine model of traumatic brain injury.
Topics: Animals; Apoptosis; Astrocytes; Behavior, Animal; Blotting, Western; Brain Injuries; Disease Models, | 2013 |
[Changes of the thyroid hormone status in children with cerebral palsy and other neurological pathology].
Topics: Age Factors; Birth Injuries; Brain Injuries; Cerebral Palsy; Child; Child, Preschool; Cystitis; Fema | 2005 |
Prevalence of anterior pituitary insufficiency 3 and 12 months after traumatic brain injury.
Topics: Adult; Brain Injuries; Estradiol; Female; Follicle Stimulating Hormone; Human Growth Hormone; Humans | 2006 |
Pituitary functions in the acute phase of traumatic brain injury: are they related to severity of the injury or mortality?
Topics: Adolescent; Adult; Age Factors; Aged; Brain Injuries; Female; Glasgow Coma Scale; Humans; Male; Midd | 2007 |
Predictors of anterior pituitary insufficiency after traumatic brain injury.
Topics: Adolescent; Adult; Aged; Brain Injuries; Estradiol; Female; Follicle Stimulating Hormone; Humans; Hy | 2008 |
[Thyroid function in craniocerebral trauma (author's transl)].
Topics: Adolescent; Aged; Brain Injuries; Female; Humans; Male; Middle Aged; Prognosis; Radioimmunoassay; Th | 1982 |
Elevated 3,5-diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors.
Topics: Astrocytoma; Brain Injuries; Brain Neoplasms; Craniocerebral Trauma; Diiodothyronines; Glioblastoma; | 1997 |
Letter: Thyroid hormones in serious non-thyroidal illness.
Topics: Acute Disease; Anemia, Pernicious; Brain Injuries; Chronic Disease; Diabetic Coma; Diabetic Ketoacid | 1976 |
Hypothalamic hypothyroidism and hypogonadism in prolonged traumatic coma.
Topics: Adult; Brain Injuries; Coma; Cyclic AMP; Follicle Stimulating Hormone; Humans; Hypogonadism; Hypothy | 1978 |
Influence of exogenous triiodothyronine on axonal regeneration and wound healing in the brain of the rat.
Topics: Animals; Axons; Brain Injuries; Cerebral Cortex; Corpus Callosum; Male; Nerve Regeneration; Rats; Tr | 1977 |
The secretion of human growth hormone stimulated by human growth hormone releasing factor following severe cranio-cerebral trauma.
Topics: Adult; Brain Injuries; Female; Glasgow Coma Scale; Growth Hormone; Growth Hormone-Releasing Hormone; | 1990 |
Catecholamine and thyroid hormones in traumatic injury.
Topics: Adolescent; Adult; Brain Injuries; Burns; Catecholamines; Craniocerebral Trauma; Female; Humans; Mal | 1990 |
[Thyroid function in severe craniocerebral injuries].
Topics: Adult; Aged; Brain Injuries; Female; Humans; Male; Middle Aged; Prognosis; Thyroid Gland; Thyroxine; | 1987 |
Hyperthyroid chorea in an elderly woman associated with sole elevation of T3.
Topics: Aged; Brain Injuries; Chorea; Female; Humans; Hyperthyroidism; Patient Compliance; Triiodothyronine | 1988 |
[Disorders of thyroid function as a consequence of severe craniocerebral injury].
Topics: Acute Disease; Brain Concussion; Brain Injuries; Humans; Hypothalamo-Hypophyseal System; Thyroid Dis | 1988 |