Page last updated: 2024-11-08

triiodothyronine and Bipolar Disorder

triiodothyronine has been researched along with Bipolar Disorder in 74 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"Two cases of patients on long-term lithium therapy are reported who developed hyperparathyroidism."7.67Chronic lithium intake and hyperparathyroidism. ( Prasad, A, 1984)
"Patients with a preexisting thyroiditis may be particularly susceptible to a rapid onset of lithium-induced hypothyroidism."7.66Lithium-induced hypothyroidism and thyroiditis. ( Berchou, R; Gupta, BK; Pohl, RB, 1979)
"A search on Medline, Limo and ScienceDirect was performed using the search terms bipolar disorder, bipolar depression, treatment resistant, treatment refractory, thyroid hormones, triiodothyronine, T3, acceleration and augmentation."4.98The use of triiodothyronine (T3) in the treatment of bipolar depression: A review of the literature. ( Parmentier, T; Sienaert, P, 2018)
"Euthyroid hyperthyroxinemia as a result of a transient increase in thyroid-stimulating hormone (TSH) levels may contribute to the development of manic disorder."3.70Thyroid function and psychiatric morbidity in patients with manic disorder receiving lithium therapy. ( Ahuja, A; Chow, CC; Lee, DT; Lee, S; Leung, TY; Mak, TW; Shek, AC; Wing, YK, 2000)
"Serum concentrations of thyrotropine (TSH), thyroxine (T4), free T4 (fT4), triiodothyronine (T3) and reverse T3 (rT3) were measured 4 x during a 12-month period in 28 patients with major depressive disorder maintained on lithium prophylaxis for 4-23 years (mean = 11."3.69The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: high triiodothyronine serum concentrations are correlated to the prophylactic efficacy. ( Baumgartner, A; Gräf, KJ; Kürten, I; Müller-Oerlinghausen, B; von Stuckrad, M, 1995)
"Medication-free inpatients with major depression or bipolar disorder were studied with oxygen-15 water and positron emission tomography (PET) to measure CBF (N = 19) or with [18F] fluorodeoxyglucose and PET to measure cerebral glucose metabolism (N = 29)."3.69Inverse relationship of peripheral thyrotropin-stimulating hormone levels to brain activity in mood disorders. ( Andreason, PJ; Callahan, AM; George, MS; Herscovitch, P; Horwitz, B; Ketter, TA; Marangell, LB; Parekh, P; Pazzaglia, PJ; Post, RM, 1997)
"Thyrotropin (TSH), thyroxine (T4), free T4, triiodothyronine (T3), and free T3 (fT3) concentrations were measured in 25 patients with major depressive disorder at 8 a."3.68Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder. ( Baumgartner, A; Gräf, KJ; Kürten, I; Meinhold, H, 1990)
"Two cases of patients on long-term lithium therapy are reported who developed hyperparathyroidism."3.67Chronic lithium intake and hyperparathyroidism. ( Prasad, A, 1984)
" In the present study, thyroid functions (TFTs) and thyrotropin-releasing hormone (TRH) stimulation of thyroid-stimulating hormone (TSH) were measured before and after treatment with desipramine (DMI) in 13 men with a diagnosis of major depressive disorder."3.67The thyroid axis and desipramine treatment in depression. ( Anton, RF; Brady, KT, 1989)
"L-Triiodothyronine (T3) has been reported to potentiate the antidepressant effects of tricyclic antidepressants (TCAs) in patients who do not respond to these drugs, while thyroxine (T4) has been used to treat rapid-cycling bipolar disorder patients."3.67Appearance of mania in drug-resistant bipolar depressed patients after treatment with L-triiodothyronine. ( Burnett, GB; Evans, DL; Garbutt, JC; Haggerty, JJ; Pedersen, CA; Strawn, SK, 1986)
"Patients with a preexisting thyroiditis may be particularly susceptible to a rapid onset of lithium-induced hypothyroidism."3.66Lithium-induced hypothyroidism and thyroiditis. ( Berchou, R; Gupta, BK; Pohl, RB, 1979)
"The literature suggests that sleep deprivation can potentiate the effect of antidepressant medication in depressed patients."2.67A clinical trial of sleep deprivation in combination with antidepressant medication. ( Leibenluft, E; Madden, PA; Moul, DE; Schwartz, PJ; Wehr, TA, 1993)
" Levothyroxine was added to the baseline medication regimen, and the dosage was increased until clinical response occurred or until side effects precluded further increase."2.67Rapid cycling bipolar affective disorder. II. Treatment of refractory rapid cycling with high-dose levothyroxine: a preliminary study. ( Bauer, MS; Whybrow, PC, 1990)
"Bipolar disorder (BD)-mania is related to the dysfunction of anterior pituitary gland, but the pituitary-thyroid interaction on the acute stage of BD has been controversial."1.62A retrospective study of pituitary-thyroid interaction in patients with first-episode of bipolar disorder type I in Mania State. ( Han, Y; Huang, T; Wang, F; Zhang, H; Zhu, Y, 2021)
"The prevalence of autoimmune thyroiditis in the general population is estimated to be at about 5-14 %."1.42Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients. ( Degner, D; Haust, M; Meller, J; Reulbach, U; Rüther, E, 2015)
" This case illustrates the potential for hypothyroid-induced renal dysfunction to lead to adverse clinical consequences in patients taking medications cleared by the kidneys."1.35Lithium toxicity precipitated by profound hypothyroidism. ( Gohh, R; Gopalakrishnan, G; Hennessey, JV; Phillips, BD, 2008)
"Piribedil is a relatively selective dopamine agonist with moderate antidepressant activity."1.27Neuroendocrine effects of the dopamine agonist piribedil in depressed patients. ( Ballenger, JC; Gold, PW; Joffe, RT; Post, RM; Rakita, R; Rebar, R, 1986)
"The TSH response in the groups with reactive depression, reactive paranoid psychosis, and neurotic depression, respectively, did not differ significantly from that found in controls."1.26Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness. ( Bjørum, N; Cohn, D; Kirkegaard, C; Lauridsen, UB, 1978)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-199036 (48.65)18.7374
1990's15 (20.27)18.2507
2000's3 (4.05)29.6817
2010's17 (22.97)24.3611
2020's3 (4.05)2.80

Authors

AuthorsStudies
Wang, X1
Luo, J1
Yuan, XF1
Chen, X1
Yu, HY1
Zhu, XQ1
Wang, G1
Qureshi, MM1
Young, AH1
Nuñez, NA1
Frye, MA4
Tost, M1
Monreal, JA1
Armario, A1
Barbero, JD2
Cobo, J2
García-Rizo, C1
Bioque, M1
Usall, J1
Huerta-Ramos, E1
Soria, V1
Labad, J1
Gan, Z1
Wu, X1
Chen, Z1
Liao, Y1
Wu, Y1
He, Z1
Yang, Z1
Zhang, Q1
Han, Y1
Zhang, H1
Huang, T1
Wang, F1
Zhu, Y1
Parmentier, T1
Sienaert, P1
Walshaw, PD1
Gyulai, L1
Bauer, M1
Bauer, MS2
Calimlim, B1
Sugar, CA1
Whybrow, PC5
Zhong, S1
Chen, G1
Zhao, L1
Jia, Y1
Chen, F1
Qi, Z1
Huang, L1
Wang, Y1
Feng, G1
Kang, C1
Yuan, J1
Zhang, Y1
Wei, Y1
Xu, L1
Zhou, F1
Fan, X1
Yang, J1
Kraszewska, A1
Ziemnicka, K1
Jończyk-Potoczna, K1
Sowiński, J1
Rybakowski, JK1
Aydin, A1
Selvi, Y1
Besiroglu, L1
Boysan, M1
Atli, A1
Ozdemir, O1
Kilic, S1
Balaharoglu, R1
Radhakrishnan, R1
Calvin, S1
Singh, JK1
Thomas, B1
Srinivasan, K1
Degner, D1
Haust, M1
Meller, J1
Rüther, E1
Reulbach, U1
Giménez-Palop, O1
Patró, E1
Pérez, M1
Bleda, F1
Oliva, JC1
Serrano, R1
Berlanga, E1
García-Parés, G1
Palao, D1
Phillips, BD1
Gopalakrishnan, G1
Gohh, R1
Hennessey, JV1
Kelly, T1
Lieberman, DZ1
Holtmann, M1
Duketis, E1
Goth, K1
Poustka, L1
Boelte, S1
Ozsoy, S1
Mavili, E1
Aydin, M1
Turan, T1
Esel, E1
Post, RM8
Altshuler, LL1
Suppes, T1
Keck, PE1
McElroy, SL1
Leverich, GS1
Luckenbaugh, DA2
Rowe, M1
Pizzarello, S1
Kupka, RW1
Grunze, H1
Nolen, WA1
Zepf, FD1
Vloet, TD1
Polier, GG1
Baurmann, D1
Bubenzer, S1
Helmbold, K1
Gaber, TJ1
Schmidt, T1
Herpertz-Dahlmann, B1
Wöckel, L1
Krishna, VN1
Thunga, R1
Unnikrishnan, B1
Kanchan, T1
Bukelo, MJ1
Mehta, RK1
Venugopal, A1
Extein, I3
Gold, MS3
Pottash, AL2
Prange, AJ3
Kjellman, BF1
Ljunggren, JG1
Beck-Friis, J1
Wetterberg, L1
Prasad, A1
Linnoila, M2
Cowdry, R1
Lamberg, BA2
Makinen, T1
Rubinow, D1
Cowdry, RW1
Potter, WZ1
Gold, PW2
Goodwin, FK2
Muscettola, G1
Lipton, MA1
Weeke, A2
Weeke, J2
Baumgartner, A3
von Stuckrad, M1
Müller-Oerlinghausen, B1
Gräf, KJ2
Kürten, I2
Tellian, FF1
Rueda-Vasquez, E1
Leibenluft, E1
Moul, DE1
Schwartz, PJ1
Madden, PA1
Wehr, TA1
Marangell, LB1
Ketter, TA1
George, MS1
Pazzaglia, PJ1
Callahan, AM2
Parekh, P1
Andreason, PJ1
Horwitz, B1
Herscovitch, P1
Kramlinger, KG1
Joffe, RT5
Roy-Byrne, PP1
Rosoff, A1
Huggins, T1
Dunn, RT1
Gary, KA1
Kimbrell, TA1
Corá-Locatelli, G1
Vanderham, E1
Winokur, A1
Valle, J1
Ayuso-Gutierrez, JL1
Abril, A1
Ayuso-Mateos, JL1
Lee, S1
Chow, CC1
Wing, YK1
Shek, AC1
Mak, TW1
Ahuja, A1
Lee, DT1
Leung, TY1
Kirkegaard, C3
Bjørum, N1
Cohn, D1
Lauridsen, UB2
Paasche, I1
Pohl, RB1
Berchou, R1
Gupta, BK1
Transbøl, I1
Christiansen, C2
Baastrup, PC1
Bech, P1
Bock, E1
Johannesen, M1
Rafaelsen, OJ1
Norlem, N1
Bjorum, N1
Wilson, DA1
Mulder, RT1
Joyce, PR1
Stern, RA1
Nevels, CT1
Shelhorse, ME1
Prohaska, ML1
Mason, GA1
Meinhold, H1
Roca, RP1
Blackman, MR1
Ackerley, MB1
Harman, SM1
Gregerman, RI1
Chopra, IJ1
Solomon, DH1
Huang, TS1
Brady, KT1
Anton, RF1
Rubinow, DR1
Uhde, TW2
Rupprecht, R1
Rupprecht, C1
Rupprecht, M1
Noder, M1
Mahlstedt, J1
Sinitskiĭ, VN1
Usherenko, LS1
Zapotochnyĭ, BA1
Kryzhanovskiĭ, LA1
Kutcher, SP1
Gow, SM1
Müller, B1
Böning, J1
Lavretskaia, EF1
Tenidieva, VD1
Lavretskaia, GI1
Gitlin, MJ1
Evans, DL1
Strawn, SK1
Haggerty, JJ1
Garbutt, JC1
Burnett, GB1
Pedersen, CA1
Ballenger, JC1
Rebar, R1
Rakita, R1
Blank, DW1
Rogers, MP1
Hanna, SM1
Jenner, FA1
Pearson, IB1
Sampson, GA1
Thompson, EA1
Takahashi, S1
Kondo, H1
Yoshimura, M1
Ochi, Y1
Ogura, C1
Okuma, T1
Uchida, Y1
Imai, S1
Yogi, H1
Hambsch, K1
Eisengräber, I1
Müller, P1
Reske, W1
Bora, SS1
Radichevich, I1
Werner, SC1
Stainbrook, E1

Reviews

7 reviews available for triiodothyronine and Bipolar Disorder

ArticleYear
Targeting Hormones for Improving Cognition in Major Mood Disorders and Schizophrenia: Thyroid Hormones and Prolactin.
    Clinical drug investigation, 2020, Volume: 40, Issue:1

    Topics: Bipolar Disorder; Cognition Disorders; Depressive Disorder, Major; Humans; Hypothyroidism; Mood Diso

2020
The use of triiodothyronine (T3) in the treatment of bipolar depression: A review of the literature.
    Journal of affective disorders, 2018, 03-15, Volume: 229

    Topics: Antidepressive Agents; Bipolar Disorder; Drug Therapy, Combination; Humans; Lithium; Triiodothyronin

2018
Psychopharmacologic treatment of depression.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Affective Disorders, Psychotic; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychot

1984
A hypothesis of thyroid-catecholamine-receptor interaction. Its relevance to affective illness.
    Archives of general psychiatry, 1981, Volume: 38, Issue:1

    Topics: Adenosine Monophosphate; Bipolar Disorder; Catecholamines; Depressive Disorder; Humans; Lithium; Moo

1981
The therapeutic use of triiodothyronine and high dose thyroxine in psychiatric disorder.
    Acta medica Austriaca, 1994, Volume: 21, Issue:2

    Topics: Bipolar Disorder; Brain; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combin

1994
Rapid cycling bipolar affective disorder: lack of relation to hypothyroidism.
    Psychiatry research, 1997, Aug-29, Volume: 72, Issue:1

    Topics: Adult; Bipolar Disorder; Female; Humans; Hypothyroidism; Male; Reference Values; Thyroid Function Te

1997
The use of thyroid supplements to augment antidepressant medication.
    The Journal of clinical psychiatry, 1998, Volume: 59 Suppl 5

    Topics: Antidepressive Agents; Bipolar Disorder; Clinical Trials as Topic; Depressive Disorder; Drug Adminis

1998

Trials

10 trials available for triiodothyronine and Bipolar Disorder

ArticleYear
Relationship of free thyroxine and triiodothyronine on recurrence in maintenance therapy for bipolar depression.
    Asian journal of psychiatry, 2022, Volume: 71

    Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Humans; Mania; Thyroxine; Triiodothyr

2022
Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: A double-blind placebo-controlled trial of levothyroxine (L-T
    Bipolar disorders, 2018, Volume: 20, Issue:7

    Topics: Adult; Affect; Bipolar Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric

2018
The use of triiodothyronine as an augmentation agent in treatment-resistant bipolar II and bipolar disorder NOS.
    Journal of affective disorders, 2009, Volume: 116, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Bipolar Disorder; Diagnostic and S

2009
Ultrasonically determined thyroid volume and thyroid functions in lithium-naïve and lithium-treated patients with bipolar disorder: a cross-sectional and longitudinal study.
    Human psychopharmacology, 2010, Volume: 25, Issue:2

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Diagnostic and Statistical Manua

2010
A clinical trial of sleep deprivation in combination with antidepressant medication.
    Psychiatry research, 1993, Volume: 46, Issue:3

    Topics: Adult; Antidepressive Agents; Bipolar Disorder; Body Temperature Regulation; Circadian Rhythm; Combi

1993
Lack of correlation between cerebrospinal fluid thyrotropin-releasing hormone (TRH) and TRH-stimulated thyroid-stimulating hormone in patients with depression.
    Biological psychiatry, 1999, Apr-15, Volume: 45, Issue:8

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Humans; Hydrocortisone; M

1999
Antidepressant and memory effects of combined thyroid hormone treatment and electroconvulsive therapy: preliminary findings.
    Biological psychiatry, 1991, Sep-15, Volume: 30, Issue:6

    Topics: Adult; Aged; Arousal; Bipolar Disorder; Combined Modality Therapy; Depressive Disorder; Double-Blind

1991
Rapid cycling bipolar affective disorder. II. Treatment of refractory rapid cycling with high-dose levothyroxine: a preliminary study.
    Archives of general psychiatry, 1990, Volume: 47, Issue:5

    Topics: Adult; Aged; Bipolar Disorder; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Bl

1990
The therapeutic effect of lithium carbonate on a patient with a forty-eight hour periodic psychosis.
    The British journal of psychiatry : the journal of mental science, 1972, Volume: 121, Issue:562

    Topics: Bipolar Disorder; Diet; Electroencephalography; Humans; Hypothyroidism; Lithium; Male; Periodicity;

1972
Artifactual elevation of PBI from an iodinated dye used to stain medicinal capsules pink.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:9

    Topics: Bipolar Disorder; Blood Proteins; Capsules; Carbonates; Chromatography, Paper; Clinical Trials as To

1969

Other Studies

57 other studies available for triiodothyronine and Bipolar Disorder

ArticleYear
The Chimera of Circular Insanity and the labours of Thyreoidea.
    Bipolar disorders, 2019, Volume: 21, Issue:8

    Topics: Bipolar Disorder; Double-Blind Method; Humans; Thyroxine; Triiodothyronine

2019
Adjunctive thyroid hormone treatment in rapid cycling bipolar disorder: A double-blind placebo-controlled trial of levothyroxine (L-T4) and triiodothyronine (T3).
    Bipolar disorders, 2019, Volume: 21, Issue:8

    Topics: Bipolar Disorder; Double-Blind Method; Humans; Thyroxine; Triiodothyronine

2019
Rapid cycling bipolar disorder is associated with antithyroid antibodies, instead of thyroid dysfunction.
    BMC psychiatry, 2019, 12-02, Volume: 19, Issue:1

    Topics: Adult; Autoantibodies; Biomarkers; Bipolar Disorder; Female; Humans; Male; Middle Aged; Thyroid Func

2019
A retrospective study of pituitary-thyroid interaction in patients with first-episode of bipolar disorder type I in Mania State.
    Medicine, 2021, Feb-12, Volume: 100, Issue:6

    Topics: Adult; Bipolar Disorder; Case-Control Studies; China; Feedback, Physiological; Female; Humans; Male;

2021
Correlation between Intrinsic Brain Activity and Thyroid-Stimulating Hormone Level in Unmedicated Bipolar II Depression.
    Neuroendocrinology, 2019, Volume: 108, Issue:3

    Topics: Adolescent; Adult; Bipolar Disorder; Case-Control Studies; Female; Functional Neuroimaging; Gyrus Ci

2019
Neuroendocrine abnormalities associated with untreated first episode patients with major depressive disorder and bipolar disorder.
    Psychoneuroendocrinology, 2019, Volume: 107

    Topics: Adrenocorticotropic Hormone; Adult; Bipolar Disorder; Depressive Disorder, Major; Endocrine System;

2019
Thyroid structure and function in long-term lithium-treated and lithium-naïve bipolar patients.
    Human psychopharmacology, 2019, Volume: 34, Issue:4

    Topics: Adult; Aged; Bipolar Disorder; Female; Humans; Lithium Compounds; Male; Middle Aged; Thyroid Gland;

2019
Mood and metabolic consequences of sleep deprivation as a potential endophenotype' in bipolar disorder.
    Journal of affective disorders, 2013, Sep-05, Volume: 150, Issue:2

    Topics: Adult; Affect; Bipolar Disorder; Case-Control Studies; Circadian Rhythm; Dehydroepiandrosterone; End

2013
Thyroid dysfunction in major psychiatric disorders in a hospital based sample.
    The Indian journal of medical research, 2013, Volume: 138, Issue:6

    Topics: Adult; Bipolar Disorder; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle Aged; Mood Di

2013
Association between autoimmune thyroiditis and depressive disorder in psychiatric outpatients.
    European archives of psychiatry and clinical neuroscience, 2015, Volume: 265, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; Bipolar Disorder; Depressive Disorder; Female; Human

2015
Lack of confirmation of thyroid endophenotype in Bipolar Disorder Type I and their first-degree relatives.
    Psychoneuroendocrinology, 2015, Volume: 51

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Bipolar Disorder; Case-Control Studies;

2015
Lithium toxicity precipitated by profound hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:6

    Topics: Bipolar Disorder; Female; Humans; Hypothyroidism; Lithium Compounds; Middle Aged; Renal Insufficienc

2008
Severe affective and behavioral dysregulation in youth is associated with increased serum TSH.
    Journal of affective disorders, 2010, Volume: 121, Issue:1-2

    Topics: Adolescent; Aggression; Antisocial Personality Disorder; Anxiety Disorders; Attention Deficit Disord

2010
Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:9

    Topics: Adult; Ambulatory Care; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antimanic Agent

2010
No association between affective and behavioral dysregulation and parameters of thyroid function in youths.
    Journal of affective disorders, 2011, Volume: 134, Issue:1-3

    Topics: Adolescent; Adult; Bipolar Disorder; Child; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; M

2011
Association between bipolar affective disorder and thyroid dysfunction.
    Asian journal of psychiatry, 2013, Volume: 6, Issue:1

    Topics: Adult; Bipolar Disorder; Cross-Sectional Studies; Female; Humans; Male; Thyroid Diseases; Thyroid Gl

2013
Reverse T3 levels in affective disorders.
    Psychiatry research, 1983, Volume: 10, Issue:1

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Male; M

1983
Chronic lithium intake and hyperparathyroidism.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:4

    Topics: Bipolar Disorder; Calcium; Chlorides; Female; Humans; Hyperparathyroidism; Lithium; Middle Aged; Sod

1984
CSF triiodothyronine (rT3) levels in patients with affective disorders.
    Biological psychiatry, 1983, Volume: 18, Issue:12

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Norepinephrine; Tri

1983
Using the protirelin test to distinguish mania from schizophrenia.
    Archives of general psychiatry, 1982, Volume: 39, Issue:1

    Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Female; Humans; Male; Schizophrenia; Thyrot

1982
High reverse T3 levels in manic an unipolar depressed women.
    Psychiatry research, 1982, Volume: 6, Issue:3

    Topics: Adult; Affective Disorders, Psychotic; Bipolar Disorder; Depressive Disorder; Female; Humans; Thyrox

1982
Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders.
    The American journal of psychiatry, 1982, Volume: 139, Issue:1

    Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Dis

1982
The 24-hour pattern of serum TSH in patients with endogenous depression.
    Acta psychiatrica Scandinavica, 1980, Volume: 62, Issue:1

    Topics: Adult; Aged; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Middle A

1980
The hypothalamic-pituitary-thyroid axis in patients maintained on lithium prophylaxis for years: high triiodothyronine serum concentrations are correlated to the prophylactic efficacy.
    Journal of affective disorders, 1995, Jun-08, Volume: 34, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Depressive Disorder; Female; Humans; Hypothalamo-H

1995
Effect of serum lithium levels on thyrotropin levels.
    Southern medical journal, 1993, Volume: 86, Issue:10

    Topics: Adult; Aged; Bipolar Disorder; Dose-Response Relationship, Drug; Humans; Hypothyroidism; Lithium Car

1993
Inverse relationship of peripheral thyrotropin-stimulating hormone levels to brain activity in mood disorders.
    The American journal of psychiatry, 1997, Volume: 154, Issue:2

    Topics: Adult; Bipolar Disorder; Brain; Cerebrovascular Circulation; Deoxyglucose; Depressive Disorder; Fema

1997
Evaluation of thyroid function in lithium-naive bipolar patients.
    European psychiatry : the journal of the Association of European Psychiatrists, 1999, Volume: 14, Issue:6

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Carbamazepine; Female; Humans; Hypothyroidism; Lithium; M

1999
Thyroid function and psychiatric morbidity in patients with manic disorder receiving lithium therapy.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:2

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Euthyroid Sick Syndromes; Female; Follow-Up Studies; Huma

2000
Thyrotrophin-releasing hormone (TRH) stimulation test in manic-depressive illness.
    Archives of general psychiatry, 1978, Volume: 35, Issue:8

    Topics: Adjustment Disorders; Adult; Age Factors; Aged; Biperiden; Bipolar Disorder; Depression; Female; Hal

1978
[Biochemistry of depression].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1976, Volume: 28, Issue:2

    Topics: Adrenocorticotropic Hormone; Bipolar Disorder; Contraceptives, Oral; Cyclic AMP; Depression; Dopamin

1976
Lithium-induced hypothyroidism and thyroiditis.
    Biological psychiatry, 1979, Volume: 14, Issue:5

    Topics: Autoantibodies; Bipolar Disorder; Humans; Hypothyroidism; Lithium; Male; Middle Aged; Thyroid Gland;

1979
Endocrine effects of lithium. I. Hypothyroidism, its prevalence in long-term treated patients.
    Acta endocrinologica, 1978, Volume: 87, Issue:4

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Female; Humans; Hypothyroidism; Lithium; Male; Middle Age

1978
Hormones, electrolytes, and cerebrospinal fluid proteins in manic-melancholic patients.
    Neuropsychobiology, 1978, Volume: 4, Issue:2

    Topics: Adolescent; Adult; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Cerebrospinal Fluid Pro

1978
Disturbed circadian variation of serum thyrotropin in patients with endogenous depression.
    Acta psychiatrica Scandinavica, 1978, Volume: 57, Issue:4

    Topics: Adult; Age Factors; Aged; Antidepressive Agents, Tricyclic; Bipolar Disorder; Circadian Rhythm; Fema

1978
Protirelin stimulation test and thyroid function during treatment of depression.
    Archives of general psychiatry, 1975, Volume: 32, Issue:9

    Topics: Adult; Aged; Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Male; Middle Aged; Sex Fac

1975
Diurnal profiles of thyroid hormones are altered in depression.
    Journal of affective disorders, 1992, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Bipolar Disorder; Circadian Rhythm; Depressive Disorder; Female; Humans; Male; Mi

1992
Thyrotropin (TSH) and thyroid hormone concentrations during partial sleep deprivation in patients with major depressive disorder.
    Journal of psychiatric research, 1990, Volume: 24, Issue:4

    Topics: Adult; Aged; Arousal; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Slee

1990
Thyroid hormone elevations during acute psychiatric illness: relationship to severity and distinction from hyperthyroidism.
    Endocrine research, 1990, Volume: 16, Issue:4

    Topics: Adult; Bipolar Disorder; Blood Pressure; Depressive Disorder; Down-Regulation; Feedback; Female; Hal

1990
Serum thyrotropin in hospitalized psychiatric patients: evidence for hyperthyrotropinemia as measured by an ultrasensitive thyrotropin assay.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Dementia; Depression; Female; Humans; Male; Mental

1990
The thyroid axis and desipramine treatment in depression.
    Biological psychiatry, 1989, Mar-15, Volume: 25, Issue:6

    Topics: Adult; Aged; Bipolar Disorder; Depressive Disorder; Desipramine; Humans; Male; Middle Aged; Psycholo

1989
Relationship between cerebrospinal fluid somatostatin and peripheral thyroid hormones with carbamazepine treatment.
    Neuropsychobiology, 1985, Volume: 14, Issue:3

    Topics: Adult; Aged; Bipolar Disorder; Carbamazepine; Female; Humans; Male; Middle Aged; Somatostatin; Thyro

1985
Triiodothyronine, thyroxine, and TSH response to dexamethasone in depressed patients and normal controls.
    Biological psychiatry, 1989, Volume: 25, Issue:1

    Topics: Adult; Aged; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Dexamethasone; Female; Fo

1989
[Effect of various biologically active substances and hormonal preparations on the pathogenetic mechanisms of manic-depressive psychoses].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:9

    Topics: Action Potentials; Adult; Bipolar Disorder; Brain; Catecholamines; Hormones; Humans; Insulin; Male;

1988
Psychiatric applications of thyroid tests.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:1 Suppl

    Topics: Antidepressive Agents, Tricyclic; Bipolar Disorder; Depressive Disorder; Diagnosis, Differential; Dr

1986
Central thyroid stimulation in severely ill depressed, manic and schizophrenic patients.
    Biological psychiatry, 1986, Volume: 21, Issue:4

    Topics: Bipolar Disorder; Depressive Disorder; Dexamethasone; Humans; Pituitary Gland, Anterior; Schizophren

1986
Free T4 measurement is preferred to the T4 test for thyroid evaluation in lithium treated patients.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:2

    Topics: Adult; Aged; Bipolar Disorder; Female; Humans; Lithium; Lithium Carbonate; Male; Middle Aged; Thyroi

1987
Changes in the pituitary-thyroid axis accompanying major affective disorders.
    Acta psychiatrica Scandinavica, 1988, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Bipolar Disorder; De

1988
[Hormonal profile of depressed patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1987, Volume: 87, Issue:4

    Topics: Adult; Aged; Bipolar Disorder; Depression; Female; Growth Hormone; Hormones; Humans; Hydrocortisone;

1987
L-triiodothyronine-precipitated angina and clinical response.
    Biological psychiatry, 1986, Volume: 21, Issue:5-6

    Topics: Angina Pectoris; Bipolar Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Huma

1986
Appearance of mania in drug-resistant bipolar depressed patients after treatment with L-triiodothyronine.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:10

    Topics: Adult; Antidepressive Agents, Tricyclic; Bipolar Disorder; Drug Therapy, Combination; Female; Humans

1986
Neuroendocrine effects of the dopamine agonist piribedil in depressed patients.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:5

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Middle Aged; Piperazines; Piribe

1986
Decreased triiodothyronines in depression: a preliminary report.
    Biological psychiatry, 1985, Volume: 20, Issue:8

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Thyroxine; Triiodothyronine

1985
Clinical hypothyroidism occurring during lithium treatment: two case histories and a review of thyroid function in 19 patients.
    The American journal of psychiatry, 1971, Volume: 128, Issue:2

    Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Hypothyroidism; Imipramine; Lithium; Male; Midd

1971
Thyrotropin responses to TRH in depressive illness: relation to clinical subtypes and prolonged duration of depressive episode.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:4

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Bipolar Disorder; Depression; Depressive Disorder, Ma

1974
Combined thyroid (triiodothyronine)-tricyclic antidepressant treatment in depressive states.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:3

    Topics: Adjustment Disorders; Adult; Amitriptyline; Antidepressive Agents; Anxiety; Bipolar Disorder; Blood

1974
[Problems in lithium-induced goiter].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1974, Oct-01, Volume: 29, Issue:19

    Topics: Adult; Bipolar Disorder; Female; Goiter; Humans; Lithium; Male; Middle Aged; Thyroid Function Tests;

1974
Clinical psychiatry.
    Progress in neurology and psychiatry, 1971, Volume: 26

    Topics: Abortion, Spontaneous; Bipolar Disorder; Brain; Carbonates; Drug Therapy, Combination; Electric Stim

1971