Page last updated: 2024-11-08

triiodothyronine and Bacterial Disease

triiodothyronine has been researched along with Bacterial Disease in 7 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"In 25 patients suffering from fever of infection, serum levels of thyrotropin (TSH), thyroxine (T4), triiodothyronine (T3), and thyroxine binding globulin (TBG) were estimated on two consecutive days during the febrile period and again 3 to 10 days after the fever had subsided."3.65Serum levels of thyrotropin, thyroid hormones and their response to thyrotropin releasing hormone in infective febrile illnesses. ( Rastogi, GK; Sawhney, RC; Talwar, KK, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boelen, A1
Kwakkel, J1
Fliers, E1
Yang, ZL1
Yang, LY1
Huang, GW1
Liu, HL1
Vierhapper, H1
Laggner, A1
Waldhäusl, W1
Grubeck-Loebenstein, B1
Kleinberger, G1
Talwar, KK1
Sawhney, RC1
Rastogi, GK1
Abe, K1
Taguchi, T1
Okuno, A1
Matsuura, N1
Takebayashi, K1
Sasaki, H1
Meinhold, H1
Gramm, HJ1
Meissner, W1
Zimmermann, J1
Schwander, J1
Dennhardt, R1
Voigt, K1
Leirer, R1
Steinbach, G1
Deschner, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effects of N-acetylcysteine on Thyroid Hormone Levels in the Low T3 Syndrome[NCT01501110]Phase 483 participants (Actual)Interventional2011-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Serum T3 Levels at 48 Hours

(NCT01501110)
Timeframe: 48 hours

Interventionng/dL (Mean)
N-acetylcysteine93.5
no Intervention96.5

Reviews

1 review available for triiodothyronine and Bacterial Disease

ArticleYear
Beyond low plasma T3: local thyroid hormone metabolism during inflammation and infection.
    Endocrine reviews, 2011, Volume: 32, Issue:5

    Topics: Acute Disease; Adipose Tissue; Bacterial Infections; Chronic Disease; Euthyroid Sick Syndromes; Gene

2011

Other Studies

6 other studies available for triiodothyronine and Bacterial Disease

ArticleYear
Tri-iodothyronine supplement protects gut barrier in septic rats.
    World journal of gastroenterology, 2003, Volume: 9, Issue:2

    Topics: Animals; Bacterial Infections; Intestines; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; T

2003
Impaired secretion of TSH in critically ill patients with 'low T4-syndrome'.
    Acta endocrinologica, 1982, Volume: 101, Issue:4

    Topics: Adult; Aged; Bacterial Infections; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone

1982
Serum levels of thyrotropin, thyroid hormones and their response to thyrotropin releasing hormone in infective febrile illnesses.
    The Journal of clinical endocrinology and metabolism, 1977, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Bacterial Infections; Female; Fever; Humans; Malaria; Male; Middle Aged; Thyrotro

1977
Recurrent acute suppurative thyroiditis.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:10

    Topics: Acute Disease; Bacterial Infections; Bacteroides Infections; Child; Humans; Male; Peptococcus; Pepto

1978
Elevated serum diiodotyrosine (DIT) in severe infections and sepsis: DIT, a possible new marker of leukocyte activity.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:4

    Topics: Bacterial Infections; Biomarkers; Diiodotyrosine; Humans; Leukocytes; Radioimmunoassay; Reference Va

1991
[Physiopathologic studies of thyroid function in calves. 4: Thyroid function and parameters of defense against infection in the calf].
    Archiv fur experimentelle Veterinarmedizin, 1986, Volume: 40, Issue:2

    Topics: Animals; Antibody Formation; Bacterial Infections; Cattle; Cattle Diseases; Phagocytosis; Thyroid Gl

1986