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triiodothyronine and Astrocytosis

triiodothyronine has been researched along with Astrocytosis in 2 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Chronic demyelination and plaque formation in multiple sclerosis is accompanied by persisting astrogliosis, negatively influencing central nervous system recovery and remyelination."1.43Regulatory effect of triiodothyronine on brain myelination and astrogliosis after cuprizone-induced demyelination in mice. ( Azimzadeh, M; Beyer, C; Clarner, T; Golestani, A; Kashani, IR; Omidi, N; Pasbakhsh, P; Zendedel, A, 2016)
"In summary, we describe an in vivo demyelination/remyelination paradigm that can be powered to determine efficacy of therapies that enhance white matter and cortical remyelination."1.43A mouse model for testing remyelinating therapies. ( Bai, CB; Benson, E; Dutta, R; Edberg, D; Kidd, G; Macklin, WB; Medicetty, S; Roholt, A; Sun, S; Trapp, B, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zendedel, A1
Kashani, IR1
Azimzadeh, M1
Pasbakhsh, P1
Omidi, N1
Golestani, A1
Beyer, C1
Clarner, T1
Bai, CB1
Sun, S1
Roholt, A1
Benson, E1
Edberg, D1
Medicetty, S1
Dutta, R1
Kidd, G1
Macklin, WB1
Trapp, B1

Other Studies

2 other studies available for triiodothyronine and Astrocytosis

ArticleYear
Regulatory effect of triiodothyronine on brain myelination and astrogliosis after cuprizone-induced demyelination in mice.
    Metabolic brain disease, 2016, Volume: 31, Issue:2

    Topics: Animals; Brain; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gliosis; Male; Mice, Inbr

2016
A mouse model for testing remyelinating therapies.
    Experimental neurology, 2016, Volume: 283, Issue:Pt A

    Topics: Animals; Axons; Brain; Calcium-Binding Proteins; Cuprizone; Demyelinating Diseases; Disease Models,

2016