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triiodothyronine and Arteriosclerosis, Coronary

triiodothyronine has been researched along with Arteriosclerosis, Coronary in 28 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"In the present work, research was carried out to explore the correlation between the high-density lipoprotein cholesterol (HDL-C)/apolipoprotein A-I (apoA-I) ratio and serum free triiodothyronine (FT3) and their interaction on the risk of coronary artery disease (CAD)."8.02The ratio of HDL-C to apoA-I interacts with free triiodothyronine to modulate coronary artery disease risk. ( Cai, G; Li, F; Li, L; Lu, W; Xiao, J; Yu, L, 2021)
"We assessed the prognostic implications of low triiodothyronine (T3) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in critically ill patients with acute heart failure."7.80Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure. ( Chuang, CP; Jong, YS; Lo, HM; Wu, CY, 2014)
"In the present work, research was carried out to explore the correlation between the high-density lipoprotein cholesterol (HDL-C)/apolipoprotein A-I (apoA-I) ratio and serum free triiodothyronine (FT3) and their interaction on the risk of coronary artery disease (CAD)."4.02The ratio of HDL-C to apoA-I interacts with free triiodothyronine to modulate coronary artery disease risk. ( Cai, G; Li, F; Li, L; Lu, W; Xiao, J; Yu, L, 2021)
"We assessed the prognostic implications of low triiodothyronine (T3) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in critically ill patients with acute heart failure."3.80Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure. ( Chuang, CP; Jong, YS; Lo, HM; Wu, CY, 2014)
"To survey the association of serum free triiodothyronine (FT3) level with coronary artery calcification and major adverse cardiac events (MACE) in outpatients with suspected coronary artery disease (CAD)."3.80[Relationship of serum free T3 with the coronary artery calcification and major adverse cardiac events in patients with suspected coronary artery disease]. ( Gao, C; Hao, P; Li, M; Liu, W; Qi, D; Wang, X; Zhang, Y; Zhu, L, 2014)
"To investigate the association between low free triiodothyronine (fT3) levels and the severity and prognosis of patients with acute myocardial infarction."3.78A low fT3 level as a prognostic marker in patients with acute myocardial infarctions. ( Li, W; Peng, W; Wang, C; Xu, Y; Zhang, B, 2012)
"These findings suggest that elevated cholesterol concentrations in the blood, especially against the background of suppressed thyroid function, can directly induce considerable damage to cardiomyocytes, intramural vessels, and erythrocytes without the development of myocardial ischemia and in the absence of atherosclerotic plaques."1.39Structural changes in the myocardium and serum lipid spectrum in experimental hypercholesterolemia and hypothyroidism. ( Klinnikova, MG; Lushnikova, EL; Molodykh, OP; Nepomnyashchikh, LM; Nepomnyashchikh, RD; Pichigin, VI; Polyakov, LP; Poteryaeva, ON; Russkikh, GS, 2013)
"Overt hypothyroidism has been found to be associated with cardiovascular disease."1.32Thyroid function is associated with presence and severity of coronary atherosclerosis. ( Auer, J; Berent, R; Eber, B; Lassnig, E; Weber, T, 2003)
"Triiodothyronine (T3) was significantly lower (P less than 0."1.27Progression and regression of human coronary atherosclerosis. The role of lipoproteins, lipases and thyroid hormones in coronary lesion growth. ( Arntzenius, AC; Barth, JD; Birkenhager, JC; Jansen, H; Kromhout, D; Reiber, JH, 1987)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.71)18.7374
1990's0 (0.00)18.2507
2000's6 (21.43)29.6817
2010's16 (57.14)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Li, L1
Cai, G1
Lu, W1
Li, F1
Yu, L1
Xiao, J1
Zhang, H1
Che, W1
Shi, K1
Huang, Y1
Xu, C1
Fei, M1
Fan, X1
Zhang, J2
Hu, X1
Hu, F1
Qin, S1
Zhang, X1
Huang, Q1
Yu, F1
Yuan, D1
Zhang, C1
Jia, S1
Liu, Y1
Jiang, L1
Xu, L1
Zhang, Y4
Xu, J1
Xu, B2
Hui, R1
Gao, R1
Gao, Z1
Song, L1
Yuan, J1
Ortolani, PD1
Romaldini, JH1
Guerra, RA1
Portes, ES1
Meireles, GCX1
Pimenta, J1
Nepomnyashchikh, LM1
Lushnikova, EL1
Polyakov, LP1
Molodykh, OP1
Klinnikova, MG1
Russkikh, GS1
Poteryaeva, ON1
Nepomnyashchikh, RD1
Pichigin, VI1
Chuang, CP1
Jong, YS1
Wu, CY1
Lo, HM1
Zhu, L2
Gao, C2
Wang, X2
Qi, D2
Li, M2
Liu, W2
Hao, P2
Kim, BK1
Chang, Y1
Ryu, S1
Cho, J1
Lee, WY2
Rhee, EJ2
Kwon, MJ1
Rampal, S1
Zhao, D1
Pastor-Barriuso, R1
Lima, JA1
Shin, H1
Guallar, E1
Park, HJ1
Kim, J1
Han, EJ1
Park, SE1
Park, CY1
Oh, KW1
Park, SW1
Zhou, Y1
Zhao, L1
Wang, T1
Hong, J1
Huang, X1
Xu, M1
Bi, Y1
Brozaitiene, J2
Mickuviene, N1
Podlipskyte, A2
Burkauskas, J1
Bunevicius, R3
Coceani, M1
Iervasi, G1
Pingitore, A1
Carpeggiani, C1
L'Abbate, A1
Tatar, E1
Kircelli, F1
Asci, G1
Carrero, JJ1
Gungor, O1
Demirci, MS1
Ozbek, SS1
Ceylan, N1
Ozkahya, M1
Toz, H1
Ok, E1
Mishra, P1
Samanta, L1
Mugii, S1
Hanada, H1
Okubo, M1
Masuda, D1
Takeoka, K1
Hidaka, Y1
Ohama, T1
Matsuyama, A1
Nakagawa-Toyama, Y1
Nishida, M1
Ishigami, M1
Komuro, I1
Yamashita, S1
Ertaş, F1
Kaya, H1
Soydinç, MS1
Bunevicius, A1
Gintauskiene, V2
Zaliunas, R1
Prange, AJ2
Zhang, B1
Peng, W1
Wang, C1
Li, W1
Xu, Y1
Mezősi, E1
Bajnok, L1
Tóth, K1
Güden, M1
Akpinar, B1
Sagğbaş, E1
Sanisoğlu, I1
Cakali, E1
Bayindir, O1
Auer, J2
Weber, T2
Eber, B2
CHURCH, G1
LAWRIE, TD1
PIRRIE, R1
HERRMANN, GR1
SAMAWI, A1
Berent, R1
Lassnig, E1
Telkova, IL1
Tepliakov, AT1
Varoneckas, G1
Hinderliter, AL1
Girdler, SS1
Barth, JD1
Jansen, H1
Kromhout, D1
Reiber, JH1
Birkenhager, JC1
Arntzenius, AC1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Endocrine Changes in Adults Undergoing Cardiac Surgery[NCT03736499]500 participants (Anticipated)Observational2018-07-01Active, not recruiting
Effects of Dapagliflozin on Hyperlipidemia, Glycemic Control and Insulin Resistance in Type 2 Diabetic Patients (DAPHNIS Study)[NCT02577159]Phase 450 participants (Anticipated)Interventional2015-07-01Active, not recruiting
Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction[NCT02512978]Phase 4160 participants (Anticipated)Interventional2015-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for triiodothyronine and Arteriosclerosis, Coronary

ArticleYear
Oxidative stress and heart failure in altered thyroid States.
    TheScientificWorldJournal, 2012, Volume: 2012

    Topics: Animals; Atherosclerosis; Cardiomyopathies; Coronary Artery Disease; Heart Defects, Congenital; Hear

2012
[The heart as an endocrine organ].
    Orvosi hetilap, 2012, Dec-23, Volume: 153, Issue:51

    Topics: Adipocytes; Adipokines; Aldosterone; Biomarkers; Cardiomegaly; Coronary Artery Disease; Cytokines; H

2012

Trials

1 trial available for triiodothyronine and Arteriosclerosis, Coronary

ArticleYear
Effects of intravenous triiodothyronine during coronary artery bypass surgery.
    Asian cardiovascular & thoracic annals, 2002, Volume: 10, Issue:3

    Topics: Aged; Arrhythmias, Cardiac; Cardiovascular System; Coronary Artery Bypass; Coronary Artery Disease;

2002

Other Studies

25 other studies available for triiodothyronine and Arteriosclerosis, Coronary

ArticleYear
The ratio of HDL-C to apoA-I interacts with free triiodothyronine to modulate coronary artery disease risk.
    BMC cardiovascular disorders, 2021, 10-19, Volume: 21, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apolipoprotein A-I; Biomarkers; Cholesterol, HDL; Coronary Angiograp

2021
FT4/FT3 ratio: A novel biomarker predicts coronary microvascular dysfunction (CMD) in euthyroid INOCA patients.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Biomarkers; Coronary Artery Disease; Humans; Myocardial Ischemia; Prospective Studies; Thyroxine; Tr

2022
Predictive value of free triiodothyronine (FT3) to free thyroxine (FT4) ratio in long-term outcomes of euthyroid patients with three-vessel coronary artery disease.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2021, 02-08, Volume: 31, Issue:2

    Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Prognosis; Prospective

2021
Association of serum thyrotropin levels with coronary artery disease documented by quantitative coronary angiography: a transversal study.
    Archives of endocrinology and metabolism, 2018, Volume: 62, Issue:4

    Topics: Age Factors; Aged; Cholesterol; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; Cr

2018
Structural changes in the myocardium and serum lipid spectrum in experimental hypercholesterolemia and hypothyroidism.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:5

    Topics: Animals; Atherosclerosis; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease;

2013
Impact of triiodothyronine and N-terminal pro-B-type natriuretic peptide on the long-term survival of critically ill patients with acute heart failure.
    The American journal of cardiology, 2014, Mar-01, Volume: 113, Issue:5

    Topics: Aged; Aged, 80 and over; Comorbidity; Coronary Artery Disease; Critical Illness; Diabetic Angiopathi

2014
The effect of low FT3 levels on coronary artery calcification and MACE in outpatients with suspected coronary artery disease.
    Coronary artery disease, 2014, Volume: 25, Issue:5

    Topics: Aged; Biomarkers; Chi-Square Distribution; China; Coronary Angiography; Coronary Artery Bypass; Coro

2014
Thyroid hormones and coronary artery calcification in euthyroid men and women.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:9

    Topics: Adult; Aged; Asymptomatic Diseases; Cohort Studies; Comorbidity; Coronary Artery Disease; Cross-Sect

2014
[Relationship of serum free T3 with the coronary artery calcification and major adverse cardiac events in patients with suspected coronary artery disease].
    Zhonghua xin xue guan bing za zhi, 2014, Volume: 42, Issue:12

    Topics: Calcinosis; Coronary Artery Disease; Heart; Humans; Kaplan-Meier Estimate; Logistic Models; Risk Fac

2014
Association of low baseline free thyroxin levels with progression of coronary artery calcification over 4 years in euthyroid subjects: the Kangbuk Samsung Health Study.
    Clinical endocrinology, 2016, Volume: 84, Issue:6

    Topics: Adult; Aged; Coronary Artery Disease; Disease Progression; Euthyroid Sick Syndromes; Female; Humans;

2016
Free Triiodothyronine Concentrations are Inversely Associated with Elevated Carotid Intima-Media Thickness in Middle-Aged and Elderly Chinese Population.
    Journal of atherosclerosis and thrombosis, 2016, Volume: 23, Issue:2

    Topics: Adult; Aged; Biomarkers; Carotid Intima-Media Thickness; China; Coronary Artery Disease; Cross-Secti

2016
Relationship and prognostic importance of thyroid hormone and N-terminal pro-B-Type natriuretic peptide for patients after acute coronary syndromes: a longitudinal observational study.
    BMC cardiovascular disorders, 2016, Feb-18, Volume: 16

    Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; C-Reactive Protein; Coronary Artery Disease; Female;

2016
Thyroid hormone and coronary artery disease: from clinical correlations to prognostic implications.
    Clinical cardiology, 2009, Volume: 32, Issue:7

    Topics: Aged; Biomarkers; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studies; Euthyroid

2009
Associations of triiodothyronine levels with carotid atherosclerosis and arterial stiffness in hemodialysis patients.
    Clinical journal of the American Society of Nephrology : CJASN, 2011, Volume: 6, Issue:9

    Topics: Carotid Artery Diseases; Carotid Intima-Media Thickness; Coronary Artery Disease; Female; Humans; Ma

2011
Thyroid function influences serum apolipoprotein B-48 levels in patients with thyroid disease.
    Journal of atherosclerosis and thrombosis, 2012, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Apolipoprotein B-48; Atherosclerosis; Case-Control Studi

2012
Low serum free triiodothyronine levels are associated with the presence and severity of coronary artery disease in the euthyroid patients: an observational study.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2012, Volume: 12, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Coronary Angiography; Coronary Artery Disease; Female; H

2012
Fatigue in patients with coronary artery disease: association with thyroid axis hormones and cortisol.
    Psychosomatic medicine, 2012, Volume: 74, Issue:8

    Topics: Adrenal Glands; Coronary Artery Disease; Cross-Sectional Studies; Exercise Test; Exercise Tolerance;

2012
A low fT3 level as a prognostic marker in patients with acute myocardial infarctions.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:21

    Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Artery Disease; Female; Humans; Kaplan-Meier Estimate;

2012
Low triiodothyronine and cardiovascular disease.
    Circulation, 2003, Jul-29, Volume: 108, Issue:4

    Topics: Biomarkers; Comorbidity; Coronary Artery Disease; Cross-Sectional Studies; Follow-Up Studies; Humans

2003
The effect of trilodothyroacetic acid on serum cholesterol and phospholipids in patients with coronary artery diseases.
    Scottish medical journal, 1957, Volume: 2, Issue:7

    Topics: Cholesterol; Coronary Artery Disease; Coronary Disease; Humans; Phospholipids; Triiodothyronine

1957
The effects of various serum cholesterol lowering procedures and agents in patients with coronary artery disease.
    Texas reports on biology and medicine, 1962, Volume: 20

    Topics: Alcohols; Cholesterol; Coronary Artery Disease; Coronary Disease; Humans; Lipotropic Agents; Thyroxi

1962
Thyroid function is associated with presence and severity of coronary atherosclerosis.
    Clinical cardiology, 2003, Volume: 26, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Coronary Angiography; Coronary Artery Disease; Cross-Sectional Studi

2003
[Changes of thyroid hormone levels in the progression of coronary arteriosclerosis].
    Klinicheskaia meditsina, 2004, Volume: 82, Issue:4

    Topics: Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Disease Progression; Heart Fail

2004
Depression and thyroid axis function in coronary artery disease: impact of cardiac impairment and gender.
    Clinical cardiology, 2006, Volume: 29, Issue:4

    Topics: Coronary Artery Disease; Depressive Disorder; Female; Humans; Hypothyroidism; Incidence; Lithuania;

2006
Progression and regression of human coronary atherosclerosis. The role of lipoproteins, lipases and thyroid hormones in coronary lesion growth.
    Atherosclerosis, 1987, Volume: 68, Issue:1-2

    Topics: Angiocardiography; Cholesterol, HDL; Coronary Artery Disease; Humans; Lipase; Lipoproteins; Male; Mi

1987