triiodothyronine has been researched along with Arrhythmia in 69 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Excerpt | Relevance | Reference |
---|---|---|
"In a group of elderly patients undergoing cardiac surgery, there was a strong association between a postoperative decrease of serum triiodothyronine levels and atrial fibrillation." | 9.11 | Atrial fibrillation in elderly patients after cardiac surgery: postoperative hemodynamics and low postoperative serum triiodothyronine. ( Huhtala, H; Kokkonen, L; Kööbi, T; Majahalme, S; Mustonen, J; Salmi, J; Tarkka, M; Virtanen, V, 2005) |
"Amiodarone-induced thyrotoxicosis is a life-threatening condition." | 7.74 | Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007) |
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease." | 7.73 | Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006) |
"Amiodarone-induced thyrotoxicosis (AIT) is a difficult management problem about which there are little published data." | 7.71 | Successful treatment of amiodarone-induced thyrotoxicosis. ( Franklyn, JA; Gammage, MD; Osman, F; Sheppard, MC, 2002) |
"Because little has been published on early effects of treatment with amiodarone on thyroid function, we studied serum total and free thyroid hormone, reverse T3, and TSH levels in patients with cardiac arrhythmias during the first 10 days of treatment with a loading dose of amiodarone by iv infusion." | 7.69 | Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia. ( Berti, S; Biagini, A; Bonini, R; Carpi, A; Chopra, IJ; Clerico, A; Iervasi, G; Manfredi, C; Palmieri, C; Ravani, M, 1997) |
"Amiodarone treatment in pregnancy might be difficult to handle because of the long half-life of the drug (14-28 days up to 2 months) and because it reduces maternal and neonatal thyroid activity." | 7.68 | Amiodarone treatment in pregnancy for dilatative cardiomyopathy with ventricular malignant extrasystole and normal maternal and neonatal outcome. ( Civitella, C; Garzetti, GG; Romanini, C; Valensise, H, 1992) |
" Since myocardial calcium uptake is increased in thyrotoxic rats, the efficacy of the calcium channel-blocking drug diltiazem in decreasing heart rate and the incidence of arrhythmias was evaluated in 11 hyperthyroid patients." | 7.67 | The effect of diltiazem, a calcium channel-blocking drug, on cardiac rate and rhythm in hyperthyroid patients. ( Bentivoglio, M; Braverman, LE; Gardini, E; Guiducci, U; Minelli, R; Montermini, M; Robuschi, G; Roti, E; Roti, S; Salvi, M, 1988) |
"Out of 20 subjects selected for refractory arrhythmias, amiodarone therapy (200 mg/day) was efficacious in 85%." | 7.67 | Amiodarone and thyroid status in refractory arrhythmias. ( Codecà, L; Colamussi, V; Giganti, M; Giovannini, G; Pelizzola, D; Piffanelli, A; Ricci, L, 1988) |
"There were no side-effects in terms of cardiac arrhythmias and no change in resting heart rate." | 6.80 | Long-term L-Triiodothyronine (T3) treatment in stable systolic heart failure patients: a randomised, double-blind, cross-over, placebo-controlled intervention study. ( Andersen, U; Dominguez, H; Faber, J; Holmager, P; Kistorp, C; Mark, P; Nygaard, B; Raymond, I; Schmidt, U; Zerahn, B, 2015) |
"Hyperthyroidism was induced by a daily injection of 2 mg T3/kg body weight for 5 days." | 5.35 | In hyperthyroid rats octylguanidine protects the heart from reperfusion damage. ( Aranda, A; Chávez, E; García, N; Hernández-Esquivel, L; Pavón, N, 2009) |
"Examining the course of cardiac arrhythmias (CA) in developed TT has established that this condition gives rise to their recurrence." | 5.32 | [The specific features of thyrotoxicosis and euthyroid hyperthyroxinemia developed due to the use of cordarone]. ( Bakalov, SA; Domogadskiĭ, SP; Golitsyn, SP; Kolesnikova, GS; Masenko, VP; Molashenko, NV; Platonova, NM; Serdiuk, SE; Sviridenko, NIu, 2004) |
"Amiodarone hydrochloride is a relatively new antiarrhythmic agent, the properties of which differ in a significant manner electrophysiologically, pharmacokinetically and structurally from those of conventional as well as other investigational antidysrhythmic compounds." | 5.27 | The clinical results of amiodarone in cardiac arrhythmias: optimal dosing. ( Ikeda, N; Kannan, R; Nademanee, K; Singh, BN, 1984) |
"Amiodarone has a good antiarrhythmic effect administered either acutely or chronically." | 5.27 | [Acute antiarrhythmia treatment with amiodarone and blood levels of thyroid hormones]. ( Fazzini, PF; Gheri, RG; Marchi, F; Multinu, D; Paladini, S; Zambaldi, G, 1987) |
"In a group of elderly patients undergoing cardiac surgery, there was a strong association between a postoperative decrease of serum triiodothyronine levels and atrial fibrillation." | 5.11 | Atrial fibrillation in elderly patients after cardiac surgery: postoperative hemodynamics and low postoperative serum triiodothyronine. ( Huhtala, H; Kokkonen, L; Kööbi, T; Majahalme, S; Mustonen, J; Salmi, J; Tarkka, M; Virtanen, V, 2005) |
" We assessed the subjects according to the Simplified Menopause Index, menstrual status, thyroid hormone measurements (thyroid stimulating hormone, free thyroxine, free triiodothyronine), the presence of Hashimoto's disease antibodies (anti-thyroid peroxidase antibody or anti-thyroglobulin antibody), the presence of Grave's disease (anti-TSH receptor antibody), markers of thyroid tumor (high thyroglobulin), and thyroid ultrasonography studies." | 3.79 | Comparison of the symptoms of menopause and symptoms of thyroid disease in Japanese women aged 35-59 years. ( Ohi, K; Oi, N, 2013) |
"Amiodarone-induced thyrotoxicosis is a life-threatening condition." | 3.74 | Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007) |
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease." | 3.73 | Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006) |
"Amiodarone-induced thyrotoxicosis developed in 31 patients (49." | 3.72 | Amiodarone-induced thyroid dysfunction in cardiac patients from areas with iodine deficiency. ( Barbu, C; Bunghez, R; Coculescu, M; Fica, S; Trifănescu, R; Ursu, H; Vârtej, I, 2004) |
"Amiodarone-induced thyrotoxicosis (AIT) is a difficult management problem about which there are little published data." | 3.71 | Successful treatment of amiodarone-induced thyrotoxicosis. ( Franklyn, JA; Gammage, MD; Osman, F; Sheppard, MC, 2002) |
"Because little has been published on early effects of treatment with amiodarone on thyroid function, we studied serum total and free thyroid hormone, reverse T3, and TSH levels in patients with cardiac arrhythmias during the first 10 days of treatment with a loading dose of amiodarone by iv infusion." | 3.69 | Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia. ( Berti, S; Biagini, A; Bonini, R; Carpi, A; Chopra, IJ; Clerico, A; Iervasi, G; Manfredi, C; Palmieri, C; Ravani, M, 1997) |
"Amiodarone treatment in pregnancy might be difficult to handle because of the long half-life of the drug (14-28 days up to 2 months) and because it reduces maternal and neonatal thyroid activity." | 3.68 | Amiodarone treatment in pregnancy for dilatative cardiomyopathy with ventricular malignant extrasystole and normal maternal and neonatal outcome. ( Civitella, C; Garzetti, GG; Romanini, C; Valensise, H, 1992) |
" Since myocardial calcium uptake is increased in thyrotoxic rats, the efficacy of the calcium channel-blocking drug diltiazem in decreasing heart rate and the incidence of arrhythmias was evaluated in 11 hyperthyroid patients." | 3.67 | The effect of diltiazem, a calcium channel-blocking drug, on cardiac rate and rhythm in hyperthyroid patients. ( Bentivoglio, M; Braverman, LE; Gardini, E; Guiducci, U; Minelli, R; Montermini, M; Robuschi, G; Roti, E; Roti, S; Salvi, M, 1988) |
" Only 6 of the 14 patients with hyperthyroxinaemia had TSH-U values in the hyperthyroid range: only one of these patients had an increased triiodothyronine." | 3.67 | [Ultra-sensitive TSH levels: an aid in the screening for amiodarone-induced thyroid dysfunction]. ( Chabrier, G; Dickelé, MC; Fellinger, F; Gasser, F; Roul, G; Sacrez, A; Sapin, R; Schlienger, JL, 1986) |
"Out of 20 subjects selected for refractory arrhythmias, amiodarone therapy (200 mg/day) was efficacious in 85%." | 3.67 | Amiodarone and thyroid status in refractory arrhythmias. ( Codecà, L; Colamussi, V; Giganti, M; Giovannini, G; Pelizzola, D; Piffanelli, A; Ricci, L, 1988) |
"Therapeutic use of the potent antiarrhythmic drug amiodarone requires early detection of impending hyperthyroidism, a potentially life-threatening adverse reaction in cardiac patients." | 3.67 | Amiodarone-treated patients with suppressed TSH test are at risk of thyrotoxicosis. ( Stäubli, M; Studer, H, 1985) |
"Amiodarone, an iodinated benzofuran derivative, has electrophysiologic effects on cardiac muscle akin to those of hypothyroidism." | 3.66 | Amiodarone and thyroid function: clinical implications during antiarrhythmic therapy. ( Nademanee, K; Singh, BN, 1983) |
" When 5 x 10(-7) to 5 x 10(-6)m l-triiodothyronine is added to the culture medium arrhythmias and or tachycardia gradually appear, just as in thyrotoxicosis in vivo." | 3.65 | Studies of isolated fetal mouse hearts in organ culture. Evidence for a direct effect of triiodothyronine in enhancing cardiac responsiveness to norepinephrine. ( Wildenthal, K, 1972) |
"There were no side-effects in terms of cardiac arrhythmias and no change in resting heart rate." | 2.80 | Long-term L-Triiodothyronine (T3) treatment in stable systolic heart failure patients: a randomised, double-blind, cross-over, placebo-controlled intervention study. ( Andersen, U; Dominguez, H; Faber, J; Holmager, P; Kistorp, C; Mark, P; Nygaard, B; Raymond, I; Schmidt, U; Zerahn, B, 2015) |
"As fasting continues, progressive ketosis develops due to the mobilization and oxidation of fatty acids." | 2.36 | Fasting: the history, pathophysiology and complications. ( Driscoll, CE; Kerndt, PR; Loxterkamp, DA; Naughton, JL, 1982) |
"60 patients with CVMC complicated with arrhythmia were continuously selected (course of disease > 3 months) and they are were diagnosed with arrhythmia by the routine 18-lead electrocardiogram and 24-hour Holter; the average follow-up time is about 2 years, during which the left ventricular end-diastolic diameter (LVEDd), left ventricular ejection fraction (LVEF), the occurrence rate of malignant arrhythmia events, immune state of T cell and thyroid hormone level (FT3, FT4, TSH, TGAb and TPOAb) were compared." | 1.46 | Relevant researches on chronic viral myocarditis (CVMC) in children, complicated with arrhythmia and thyroid hormone level. ( An, XJ; Fu, MY; Li, CL; Wang, QW; Xu, F; Xue, Y, 2017) |
" Compared to vehicle-treated MI, the oral T3-treated MI group at 2 mo had markedly improved anesthetized Magnetic Resonance Imaging-based LV ejection fraction and volumes without significant negative changes in heart rate, serum TH levels or heart weight, indicating safe therapy." | 1.43 | Safe Oral Triiodo-L-Thyronine Therapy Protects from Post-Infarct Cardiac Dysfunction and Arrhythmias without Cardiovascular Adverse Effects. ( Balasubramanian, K; Chen, YF; Gerdes, AM; Ojamaa, K; Pingitore, A; Pol, CJ; Rajagopalan, V; Saunders, D; Towner, RA; Zhang, Y, 2016) |
"Hyperthyroidism was induced by a daily injection of 2 mg T3/kg body weight for 5 days." | 1.35 | In hyperthyroid rats octylguanidine protects the heart from reperfusion damage. ( Aranda, A; Chávez, E; García, N; Hernández-Esquivel, L; Pavón, N, 2009) |
"Examining the course of cardiac arrhythmias (CA) in developed TT has established that this condition gives rise to their recurrence." | 1.32 | [The specific features of thyrotoxicosis and euthyroid hyperthyroxinemia developed due to the use of cordarone]. ( Bakalov, SA; Domogadskiĭ, SP; Golitsyn, SP; Kolesnikova, GS; Masenko, VP; Molashenko, NV; Platonova, NM; Serdiuk, SE; Sviridenko, NIu, 2004) |
"Subclinical hyperthyroidism has been associated with harmful cardiac effects, but its treatment remains controversial." | 1.32 | The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities. ( Garbeline, B; Romaldini, JH; Sgarbi, JA; Villaça, FG; Villar, HE, 2003) |
"Arrhythmias were determined in ex vivo Langendorff-perfused hearts, subjected to a 30-min main left coronary artery occlusion, followed by 30-min reperfusion." | 1.31 | Streptozotocin diabetes protects against arrhythmias in rat isolated hearts: role of hypothyroidism. ( Beastall, GH; Furman, BL; Parratt, JR; Pyne, NJ; Zhang, L, 2002) |
"Amiodarone was administered by i." | 1.30 | Acute effects of intravenous amiodarone on sulphate metabolites of thyroid hormones in arrhythmic patients. ( Biagini, A; Chopra, IJ; Clerico, A; Iervasi, G; Manfredi, C; Sabatino, L, 1997) |
"It is stated that CHD patients with arrhythmia develop latent hypothyrosis of T3-low-syndrome type." | 1.29 | [The effect of kordaron on thyroid function in patients with ischemic heart disease]. ( Tereshchenko, IV; Tsepelev, VV, 1995) |
"Hypothyroidism was diagnosed in 11 patients (12%), and a further 11 had tests consistent with a "failing thyroid." | 1.27 | Effect of amiodarone on thyroid hormone economy. ( Glick, S; Posner, J; Sobel, RJ, 1984) |
"Amiodarone hydrochloride is a relatively new antiarrhythmic agent, the properties of which differ in a significant manner electrophysiologically, pharmacokinetically and structurally from those of conventional as well as other investigational antidysrhythmic compounds." | 1.27 | The clinical results of amiodarone in cardiac arrhythmias: optimal dosing. ( Ikeda, N; Kannan, R; Nademanee, K; Singh, BN, 1984) |
"Amiodarone has a good antiarrhythmic effect administered either acutely or chronically." | 1.27 | [Acute antiarrhythmia treatment with amiodarone and blood levels of thyroid hormones]. ( Fazzini, PF; Gheri, RG; Marchi, F; Multinu, D; Paladini, S; Zambaldi, G, 1987) |
"Atrial fibrillation was the commonest arrhythmia." | 1.27 | [Role of the TRF test in the study of atrial dysrhythmia]. ( Chamontin, B; Guittard, J; Salvador, M, 1983) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 35 (50.72) | 18.7374 |
1990's | 8 (11.59) | 18.2507 |
2000's | 16 (23.19) | 29.6817 |
2010's | 9 (13.04) | 24.3611 |
2020's | 1 (1.45) | 2.80 |
Authors | Studies |
---|---|
Rajagopalan, V | 3 |
Gorecki, M | 1 |
Costello, C | 1 |
Schultz, E | 1 |
Zhang, Y | 3 |
Gerdes, AM | 3 |
Fu, MY | 1 |
Wang, QW | 1 |
Xue, Y | 1 |
Xu, F | 1 |
Li, CL | 1 |
An, XJ | 1 |
Zhang, K | 1 |
Tang, YD | 1 |
Ojamaa, K | 3 |
Li, Y | 1 |
Saini, AS | 1 |
Carrillo-Sepulveda, MA | 1 |
Jiskra, J | 1 |
Límanová, Z | 1 |
Holmager, P | 1 |
Schmidt, U | 1 |
Mark, P | 1 |
Andersen, U | 1 |
Dominguez, H | 1 |
Raymond, I | 1 |
Zerahn, B | 1 |
Nygaard, B | 1 |
Kistorp, C | 1 |
Faber, J | 1 |
Chen, YF | 1 |
Pingitore, A | 1 |
Pol, CJ | 1 |
Saunders, D | 1 |
Balasubramanian, K | 1 |
Towner, RA | 1 |
Brent, GA | 1 |
Pavón, N | 1 |
Aranda, A | 1 |
García, N | 1 |
Hernández-Esquivel, L | 1 |
Chávez, E | 1 |
Roepke, TK | 1 |
King, EC | 1 |
Reyna-Neyra, A | 1 |
Paroder, M | 1 |
Purtell, K | 1 |
Koba, W | 1 |
Fine, E | 1 |
Lerner, DJ | 1 |
Carrasco, N | 1 |
Abbott, GW | 1 |
Portman, MA | 1 |
Slee, A | 1 |
Olson, AK | 1 |
Cohen, G | 1 |
Karl, T | 1 |
Tong, E | 1 |
Hastings, L | 1 |
Patel, H | 1 |
Reinhartz, O | 1 |
Mott, AR | 1 |
Mainwaring, R | 1 |
Linam, J | 1 |
Danzi, S | 1 |
Talukder, MA | 1 |
Yang, F | 1 |
Nishijima, Y | 1 |
Chen, CA | 1 |
Xie, L | 1 |
Mahamud, SD | 1 |
Kalyanasundaram, A | 1 |
Bonagura, JD | 1 |
Periasamy, M | 1 |
Zweier, JL | 1 |
Kaminski, G | 1 |
Makowski, K | 1 |
Michałkiewicz, D | 1 |
Kowal, J | 1 |
Ruchala, M | 1 |
Szczepanek, E | 1 |
Gielerak, G | 1 |
Oi, N | 1 |
Ohi, K | 1 |
Güden, M | 1 |
Akpinar, B | 1 |
Sagğbaş, E | 1 |
Sanisoğlu, I | 1 |
Cakali, E | 1 |
Bayindir, O | 1 |
Sgarbi, JA | 1 |
Villaça, FG | 1 |
Garbeline, B | 1 |
Villar, HE | 1 |
Romaldini, JH | 1 |
WOLLENBERGER, A | 1 |
Telkova, IL | 1 |
Karpov, RS | 1 |
Molashenko, NV | 1 |
Sviridenko, NIu | 1 |
Platonova, NM | 1 |
Kolesnikova, GS | 1 |
Golitsyn, SP | 1 |
Bakalov, SA | 1 |
Serdiuk, SE | 1 |
Masenko, VP | 1 |
Domogadskiĭ, SP | 1 |
Kokkonen, L | 1 |
Majahalme, S | 1 |
Kööbi, T | 1 |
Virtanen, V | 1 |
Salmi, J | 1 |
Huhtala, H | 1 |
Tarkka, M | 1 |
Mustonen, J | 1 |
Trifănescu, R | 1 |
Fica, S | 1 |
Barbu, C | 1 |
Vârtej, I | 1 |
Ursu, H | 1 |
Bunghez, R | 1 |
Coculescu, M | 1 |
O'Sullivan, AJ | 1 |
Lewis, M | 1 |
Diamond, T | 1 |
Berti, P | 1 |
Materazzi, G | 1 |
Bogazzi, F | 1 |
Ambrosini, CE | 1 |
Martino, E | 1 |
Miccoli, P | 1 |
Spratt, DI | 1 |
Frohnauer, M | 1 |
Cyr-Alves, H | 1 |
Kramer, RS | 1 |
Lucas, FL | 1 |
Morton, JR | 1 |
Cox, DF | 1 |
Becker, K | 1 |
Devlin, JT | 1 |
Venditti, P | 1 |
Bari, A | 1 |
Di Stefano, L | 1 |
Agnisola, C | 1 |
Di Meo, S | 1 |
Singh, BN | 6 |
Nademanee, K | 4 |
Kannan, R | 1 |
Ikeda, N | 1 |
McKenna, WJ | 1 |
Rowland, E | 1 |
Krikler, DM | 1 |
Chamontin, B | 1 |
Guittard, J | 1 |
Salvador, M | 1 |
Posner, J | 1 |
Sobel, RJ | 1 |
Glick, S | 1 |
de los Angeles Valenzuela, M | 1 |
Bianchi, C | 1 |
Meruane, J | 1 |
Pineda, G | 1 |
Livshits, GIa | 1 |
Kerndt, PR | 1 |
Naughton, JL | 1 |
Driscoll, CE | 1 |
Loxterkamp, DA | 1 |
Melmed, S | 1 |
Reed, AW | 1 |
Hendrickson, JA | 1 |
Hershman, JM | 2 |
Stäubli, M | 2 |
Bischof, P | 1 |
Wimpfheimer, C | 1 |
Studer, H | 2 |
Tereshchenko, IV | 1 |
Tsepelev, VV | 1 |
Biondi, B | 1 |
Fazio, S | 1 |
Carella, C | 1 |
Amato, G | 1 |
Cittadini, A | 1 |
Lupoli, G | 1 |
Saccà, L | 1 |
Bellastella, A | 1 |
Lombardi, G | 1 |
Iervasi, G | 2 |
Clerico, A | 2 |
Bonini, R | 1 |
Manfredi, C | 2 |
Berti, S | 1 |
Ravani, M | 1 |
Palmieri, C | 1 |
Carpi, A | 1 |
Biagini, A | 2 |
Chopra, IJ | 2 |
Sabatino, L | 1 |
Klein, I | 1 |
Zhang, L | 1 |
Parratt, JR | 1 |
Beastall, GH | 1 |
Pyne, NJ | 1 |
Furman, BL | 1 |
Osman, F | 1 |
Franklyn, JA | 2 |
Sheppard, MC | 2 |
Gammage, MD | 2 |
Grossi, M | 1 |
Blasi, N | 1 |
Santori, L | 1 |
Heyma, P | 1 |
Larkins, RG | 1 |
Perry-Keene, D | 1 |
Peter, CT | 1 |
Ross, D | 1 |
Sloman, JG | 1 |
Lüderitz, B | 1 |
Valensise, H | 1 |
Civitella, C | 1 |
Garzetti, GG | 1 |
Romanini, C | 1 |
Yoshihara, K | 1 |
Fukui, T | 1 |
Matsui, Y | 1 |
Koike, N | 1 |
Venkatesh, N | 1 |
Lynch, JJ | 1 |
Uprichard, AC | 1 |
Kitzen, JM | 1 |
Lucchesi, BR | 1 |
Segal, J | 1 |
Schwalb, H | 1 |
Shmorak, V | 1 |
Uretzky, G | 1 |
Gheri, RG | 1 |
Marchi, F | 1 |
Zambaldi, G | 1 |
Multinu, D | 1 |
Paladini, S | 1 |
Fazzini, PF | 1 |
Roti, E | 1 |
Montermini, M | 1 |
Roti, S | 1 |
Gardini, E | 1 |
Robuschi, G | 1 |
Minelli, R | 1 |
Salvi, M | 1 |
Bentivoglio, M | 1 |
Guiducci, U | 1 |
Braverman, LE | 1 |
Schlienger, JL | 1 |
Dickelé, MC | 1 |
Roul, G | 1 |
Sapin, R | 1 |
Chabrier, G | 1 |
Gasser, F | 1 |
Fellinger, F | 1 |
Sacrez, A | 1 |
Piffanelli, A | 1 |
Pelizzola, D | 1 |
Ricci, L | 1 |
Codecà, L | 1 |
Giovannini, G | 1 |
Giganti, M | 1 |
Colamussi, V | 1 |
Barańska, H | 1 |
Frank-Piskorska, A | 1 |
Konieczna, M | 1 |
Donaghue, KC | 1 |
Clarke, P | 1 |
Hooper, MJ | 1 |
Sugawara, M | 1 |
Pekary, AE | 1 |
Ross, R | 1 |
DiStefano, JJ | 1 |
Meese, R | 1 |
Smitherman, TC | 1 |
Croft, CH | 1 |
Burger, A | 3 |
Nicod, P | 1 |
Davis, JR | 1 |
Littler, WA | 1 |
Ramsden, DB | 1 |
Zhou, YF | 1 |
Huang, DX | 1 |
Li, ZJ | 1 |
Zurcher, H | 2 |
Sakoloff, C | 2 |
Vallotton, MB | 2 |
Wils, JA | 1 |
Kloppenborg, PW | 1 |
Herrmann, J | 1 |
Hilger, P | 1 |
Rusche, HJ | 1 |
Krüskemper, HL | 1 |
el-Khodary, AZ | 1 |
Thiffault, C | 1 |
Deschenes, L | 1 |
Couture, J | 1 |
Vána, S | 1 |
Nĕmec, J | 1 |
Svorcík, C | 1 |
Wildenthal, K | 2 |
Conte, N | 1 |
Macrì, C | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Triostat in Children During CardioPulmonary Bypass (CPB)[NCT00027417] | Phase 3 | 195 participants (Actual) | Interventional | 2001-04-30 | Completed | ||
Oral Triiodothyronine Normalizes T3 Levels After Surgery For Pediatric Congenital Heart Disease[NCT01780584] | Phase 2 | 45 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
Tetronine (Sodium Liothyronine) for Infants & Children Undergoing Cardiopulmonary Bypass in a Middle Income Nation (OTICC Study)[NCT02222532] | Phase 3 | 224 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
Effect of Levothyroxine on Serum Adiponectin, Insulin Resistance and Cardiovascular Risk in Patients With Hypothyroidism[NCT02467244] | 120 participants (Actual) | Observational | 2017-02-01 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Specific symptoms of hyperthyroidism included cardiac dysrhythmia requiring medical or electrical treatment, hypertension (mean systolic or diastolic blood pressure more than 2 standard deviation above normal for age) and hyperthermia (>37.5 degree Celsius). One patient in low dose group had hypertension directly after surgery due to unrecognized coarctation of the aorta and this patient was withdrawal from the protocol. (NCT01780584)
Timeframe: Since the first dose of oral T3 until 7 days after surgery
Intervention | participants (Number) |
---|---|
Placebo | 0 |
Oral T3 Low Dose | 1 |
Oral T3 High Dose | 0 |
(NCT01780584)
Timeframe: up to 3 month after surgery
Intervention | days (Median) |
---|---|
Placebo | 6 |
Oral T3 Low Dose | 17.5 |
Oral T3 High Dose | 10 |
(NCT01780584)
Timeframe: up to 3 months after surgery
Intervention | hours (Median) |
---|---|
Placebo | 48.5 |
Oral T3 Low Dose | 109.5 |
Oral T3 High Dose | 87 |
Postoperative time to extubation is length of time on ventilator. (NCT01780584)
Timeframe: up to 3 months after surgery
Intervention | hours (Median) |
---|---|
Placebo | 23 |
Oral T3 Low Dose | 36.5 |
Oral T3 High Dose | 17 |
Free T3 levels were measured up to 36 hours after cross-clamp removal (NCT01780584)
Timeframe: during the first 36 hours after cross clamp removal
Intervention | pg/ml (Mean) | ||||
---|---|---|---|---|---|
hour 0 | hour 1 | hour 6 | hour 18 | hour 36 | |
Oral T3 High Dose | 3.9 | 4.3 | 3.7 | 3.8 | 4.4 |
Oral T3 Low Dose | 4.5 | 4.1 | 3.3 | 2.6 | 2.1 |
Placebo | 3.6 | 3.6 | 2.9 | 2.4 | 1.6 |
6 reviews available for triiodothyronine and Arrhythmia
Article | Year |
---|---|
Clinical practice. Graves' disease.
Topics: Adrenergic beta-Antagonists; Adult; Antithyroid Agents; Arrhythmias, Cardiac; Female; Graves Disease | 2008 |
[Role of thyroid hormones in regulation of heart function].
Topics: Arrhythmias, Cardiac; Heart; Heart Conduction System; Heart Failure; Heart Rate; Humans; Hyperthyroi | 2004 |
Amiodarone: historical development and pharmacologic profile.
Topics: Action Potentials; Amiodarone; Angina Pectoris; Animals; Arrhythmias, Cardiac; Benzofurans; Electrop | 1983 |
Amiodarone: the experience of the past decade.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Drug Interactions; | 1983 |
Fasting: the history, pathophysiology and complications.
Topics: Adult; Amino Acids; Arrhythmias, Cardiac; Body Weight; Fasting; Glucagon; Gluconeogenesis; Gout; Hum | 1982 |
Thyroid hormone and the cardiovascular system.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart; Heart Diseases | 2001 |
6 trials available for triiodothyronine and Arrhythmia
Article | Year |
---|---|
Long-term L-Triiodothyronine (T3) treatment in stable systolic heart failure patients: a randomised, double-blind, cross-over, placebo-controlled intervention study.
Topics: Aged; Aged, 80 and over; Arrhythmias, Cardiac; Double-Blind Method; Female; Heart Failure, Systolic; | 2015 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Triiodothyronine Supplementation in Infants and Children Undergoing Cardiopulmonary Bypass (TRICC): a multicenter placebo-controlled randomized trial: age analysis.
Topics: Age Factors; Arrhythmias, Cardiac; Cardiopulmonary Bypass; Child, Preschool; Double-Blind Method; Fe | 2010 |
Effects of intravenous triiodothyronine during coronary artery bypass surgery.
Topics: Aged; Arrhythmias, Cardiac; Cardiovascular System; Coronary Artery Bypass; Coronary Artery Disease; | 2002 |
Atrial fibrillation in elderly patients after cardiac surgery: postoperative hemodynamics and low postoperative serum triiodothyronine.
Topics: Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac Surgical Procedures; Female; Hemodynamics; | 2005 |
Physiological effects of nonthyroidal illness syndrome in patients after cardiac surgery.
Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Dose-Response Relationship, Drug; Double-Blind Method; | 2007 |
Thyroid hormone levels and protein binding in patients on long-term diphenylhydantoin treatment.
Topics: Adult; Aged; Arrhythmias, Cardiac; Depression, Chemical; Female; Humans; Male; Middle Aged; Phenytoi | 1977 |
57 other studies available for triiodothyronine and Arrhythmia
Article | Year |
---|---|
Cardioprotection by triiodothyronine following caloric restriction via long noncoding RNAs.
Topics: Animals; Arrhythmias, Cardiac; Body Weight; Caloric Restriction; Cardiotonic Agents; Female; Male; M | 2020 |
Relevant researches on chronic viral myocarditis (CVMC) in children, complicated with arrhythmia and thyroid hormone level.
Topics: Adolescent; Arrhythmias, Cardiac; Case-Control Studies; Child; Chronic Disease; Electrocardiography; | 2017 |
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele | 2018 |
[Resistance to thyroid hormones].
Topics: Arrhythmias, Cardiac; Humans; Mutation; Thyroid Hormone Receptors beta; Thyroid Hormone Resistance S | 2014 |
Safe Oral Triiodo-L-Thyronine Therapy Protects from Post-Infarct Cardiac Dysfunction and Arrhythmias without Cardiovascular Adverse Effects.
Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Female; Magnetic Resonance Imaging; Myocardial | 2016 |
In hyperthyroid rats octylguanidine protects the heart from reperfusion damage.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium; Guanidines; Hyperthyroidism; Interferon-gamm | 2009 |
Kcne2 deletion uncovers its crucial role in thyroid hormone biosynthesis.
Topics: Animals; Arrhythmias, Cardiac; Cardiomegaly; Crosses, Genetic; Heterozygote; Homozygote; Hypothyroid | 2009 |
Detrimental effects of thyroid hormone analog DITPA in the mouse heart: increased mortality with in vivo acute myocardial ischemia-reperfusion.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Blotting, Western; Cardiotonic Agents; Data Interpret | 2011 |
The influence of subclinical hyperthyroidism on blood pressure, heart rate variability, and prevalence of arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diastole; | 2012 |
Comparison of the symptoms of menopause and symptoms of thyroid disease in Japanese women aged 35-59 years.
Topics: Adult; Arrhythmias, Cardiac; Autoantibodies; Diagnosis, Differential; Female; Flushing; Graves Disea | 2013 |
The effects of early antithyroid therapy for endogenous subclinical hyperthyroidism in clinical and heart abnormalities.
Topics: Adolescent; Adult; Aged; Antithyroid Agents; Arrhythmias, Cardiac; Diastole; Echocardiography; Elect | 2003 |
RHYTHMIC AND ARRHYTHMIC CONTRACTILE ACTIVITY OF SINGLE MYOCARDIAL CELLS CULTURED IN VITRO.
Topics: Adrenocorticotropic Hormone; Animals; Arrhythmias, Cardiac; Catecholamines; Cell Physiological Pheno | 1964 |
[The specific features of thyrotoxicosis and euthyroid hyperthyroxinemia developed due to the use of cordarone].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autoantibodies; Blood Flow Velocity; Elect | 2004 |
Amiodarone-induced thyroid dysfunction in cardiac patients from areas with iodine deficiency.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Hu | 2004 |
Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Goiter, Nodular; Graves Disease; Humans; Male | 2006 |
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study.
Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B | 2007 |
Effect of T3 treatment on the response to ischemia-reperfusion of heart preparations from sedentary and trained rats.
Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Disease Models, Animal; Hydrogen Peroxide; Hyperthyroid | 2008 |
The clinical results of amiodarone in cardiac arrhythmias: optimal dosing.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Dose-Response Relationship, Drug; Heart Conduction Sy | 1984 |
Amiodarone and thyroid function: clinical implications during antiarrhythmic therapy.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Humans; Hyperthyroidism; Hypothyroidism; Iodides; Mal | 1983 |
[Role of the TRF test in the study of atrial dysrhythmia].
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Heart Atria; Humans; Hyperthyroidism; Male; Middle Aged; | 1983 |
Effect of amiodarone on thyroid hormone economy.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Hyperthyroidism; Hypothy | 1984 |
[Usefulness of the reverse T3 (rT3) determination in patients under chronic treatment with amiodarone].
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Male; Middle Aged; Thyro | 1984 |
[Radioimmunoassay in the diagnosis of atypical forms of thyrotoxicosis].
Topics: Adult; Arrhythmias, Cardiac; Humans; Hyperthyroidism; Iodine Radioisotopes; Middle Aged; Radioimmuno | 1984 |
Hyperthyroxinemia with bradycardia and normal thyrotropin secretion after chronic amiodarone administration.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Heart Rate; Humans; Male; Middle Aged; Thyroid | 1981 |
[Amiodarone and the thyroid gland].
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Hyperthyroidism; Hypothy | 1981 |
[The effect of kordaron on thyroid function in patients with ischemic heart disease].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Hypothyroidism; Male; Middle Aged; Myocardia | 1995 |
Cardiac effects of long term thyrotropin-suppressive therapy with levothyroxine.
Topics: Adult; Arrhythmias, Cardiac; Blood Pressure; Cardiomegaly; Echocardiography; Electrocardiography; El | 1993 |
Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Kinetics; Male; Middle Aged; Thyroid Disease | 1997 |
Acute effects of intravenous amiodarone on sulphate metabolites of thyroid hormones in arrhythmic patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia | 1997 |
Streptozotocin diabetes protects against arrhythmias in rat isolated hearts: role of hypothyroidism.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Body Temperature; Body Weight; Diabetes Mellitus, Expe | 2002 |
Successful treatment of amiodarone-induced thyrotoxicosis.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Autoantibodies; Carbimazole; Cohort Studies; Female; Humans; | 2002 |
["Twisted peak" ventricular fibrillation in myxedema. Case report].
Topics: Arrhythmias, Cardiac; Electric Stimulation; Female; Humans; Hypercholesterolemia; Middle Aged; Myxed | 1979 |
[Heart function in hyperthyroidism].
Topics: Action Potentials; Age Factors; Animals; Arrhythmias, Cardiac; Atrial Flutter; Cardiac Glycosides; C | 1975 |
Amiodarone treatment in pregnancy for dilatative cardiomyopathy with ventricular malignant extrasystole and normal maternal and neonatal outcome.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomyopathy, Dilated; Echo | 1992 |
Holter ECG recordings before and after surgical treatment of hyperthyroidism: circadian pattern of heart rate and arrhythmias.
Topics: Adult; Arrhythmias, Cardiac; Circadian Rhythm; Electrocardiography, Ambulatory; Heart Rate; Humans; | 1992 |
Hypothyroidism renders protection against lethal ventricular arrhythmias in a conscious canine model of sudden death.
Topics: Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dogs; Electroencephalography; Electrophysiolo | 1991 |
Effect of anesthesia on cardiac function and response in the perfused rat heart.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Calcium; Heart; Hemodynamics; In Vitro Technique | 1990 |
[Acute antiarrhythmia treatment with amiodarone and blood levels of thyroid hormones].
Topics: Amiodarone; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Female; Humans; Male; Middle Aged; T | 1987 |
The effect of diltiazem, a calcium channel-blocking drug, on cardiac rate and rhythm in hyperthyroid patients.
Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Diltiazem; Drug Administration Schedule; | 1988 |
[Ultra-sensitive TSH levels: an aid in the screening for amiodarone-induced thyroid dysfunction].
Topics: Amiodarone; Arrhythmias, Cardiac; Female; Humans; Hyperthyroidism; Male; Middle Aged; Thyrotropin; T | 1986 |
Amiodarone and thyroid status in refractory arrhythmias.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Evaluation; El | 1988 |
[Effect of short-term administration of phenytoin on blood serum levels of thyroid hormones].
Topics: Adult; Aged; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Phenytoin; Thyroxine; Triiodot | 1987 |
Amiodarone-treated patients with suppressed TSH test are at risk of thyrotoxicosis.
Topics: Adolescent; Adult; Aged; Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Female; Hum | 1985 |
Amiodarone. The dilemma of hyperthyroxinaemia and the treatment of thyrotoxicosis.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Carbimazole; Coronary Disease; Humans; Hyperthy | 1985 |
Thyroxine and triiodothyronine kinetics in cardiac patients taking amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans; Humans; Kinetics; Middl | 1986 |
Effect of peripheral thyroid hormone metabolism on cardiac arrhythmias.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Humans; Iopanoic Acid; Male; Middle Aged | 1985 |
Amiodarone and thyroid hormone action.
Topics: Adult; Aged; Amiodarone; Animals; Arrhythmias, Cardiac; Benzofurans; Cell Nucleus; Coronary Disease; | 1985 |
[Role of the dynamic changes in serum rT3 levels during long-term administration of amiodarone].
Topics: Adolescent; Adult; Aged; Amiodarone; Animals; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Mal | 1985 |
[Clinical significance of serum triiodothyronine].
Topics: Arrhythmias, Cardiac; Diagnosis, Differential; Goiter; Goiter, Nodular; Graves Disease; Humans; Hype | 1973 |
Recurrence of hyperthyroidism shortly after return of normal suppressibility by triiodothyronine.
Topics: Adult; Antithyroid Agents; Arrhythmias, Cardiac; Emotions; Female; Graves Disease; Humans; Imidazole | 1970 |
[Plasmapheresis in the treatment of thyrotoxic crisis (author's transl)].
Topics: Arrhythmias, Cardiac; Blood Volume; Evaluation Studies as Topic; Female; Humans; Middle Aged; Plasma | 1974 |
[Preparation for surgical treatment of hyperthyroidism with the aid of propranolol: study of 15 cases].
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Hyperthyroidism; Iodin | 1974 |
[Proceedings: Clinical importance of serum triiodothyronine].
Topics: Arrhythmias, Cardiac; Goiter; Graves Disease; Humans; Hyperthyroidism; Triiodothyronine | 1974 |
[Use of hypometabolic therapy in an unusual antiarrhythmic indication].
Topics: Arrhythmias, Cardiac; Drug Therapy, Combination; Electrocardiography; Female; Heart Block; Humans; H | 1974 |
Studies of isolated fetal mouse hearts in organ culture. Evidence for a direct effect of triiodothyronine in enhancing cardiac responsiveness to norepinephrine.
Topics: Animals; Arrhythmias, Cardiac; Drug Interactions; Drug Synergism; Fetus; Heart Atria; Heart Rate; Mi | 1972 |
Responses to cardioactive drugs of fetal mouse hearts maintained in organ culture.
Topics: Acetylcholine; Animals; Arrhythmias, Cardiac; Bradycardia; Culture Techniques; Digitalis Glycosides; | 1971 |
[Electrocardiographic observations in the first phase of opotherapy of hypothyroidism].
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Hypertensio | 1967 |