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triiodothyronine and Acute Promyelocytic Leukemia

triiodothyronine has been researched along with Acute Promyelocytic Leukemia in 3 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"The human acute promyelocytic leukemia (APL) cell line HL-60 differentiates to functionally mature granulocytes by incubation with all-trans-retinoic acid (RA)."1.293,5,3'-Triiodothyronine stimulates retinoic acid-induced differentiation in HL-60 cells. ( Miyoshi, Y; Nakamura, H; Nakao, K; Sasaki, S; Tagami, T, 1994)
"Treatment of two acute promyelocytic leukemia patients with ATRA induced maximal 2."1.29An in vitro system for identifying agents capable of changing serum lipoprotein(a) concentration by regulating the transcriptional activity of the apolipoprotein(a) gene promoter. ( Azuma, H; Kanagawa, Y; Mima, N; Miyamoto, K; Saito, S; Shigekiyo, T; Shirakawa, M; Watanabe, A; Yamaguchi, H, 1996)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miyoshi, Y1
Nakamura, H1
Tagami, T1
Sasaki, S1
Nakao, K1
Azuma, H1
Yamaguchi, H1
Mima, N1
Shirakawa, M1
Miyamoto, K1
Kanagawa, Y1
Watanabe, A1
Shigekiyo, T1
Saito, S1
Takahashi, N1
Breitman, TR1

Other Studies

3 other studies available for triiodothyronine and Acute Promyelocytic Leukemia

ArticleYear
3,5,3'-Triiodothyronine stimulates retinoic acid-induced differentiation in HL-60 cells.
    Molecular and cellular endocrinology, 1994, Volume: 103, Issue:1-2

    Topics: 1-Methyl-3-isobutylxanthine; Binding Sites; Cell Differentiation; Cell Nucleus; Cyclic AMP; Drug Syn

1994
An in vitro system for identifying agents capable of changing serum lipoprotein(a) concentration by regulating the transcriptional activity of the apolipoprotein(a) gene promoter.
    Biochemical and biophysical research communications, 1996, Oct-14, Volume: 227, Issue:2

    Topics: Adult; Apolipoproteins; Apoprotein(a); Base Sequence; Cell Line; Danazol; DNA; DNA Primers; Female;

1996
Covalent modification of proteins by ligands of steroid hormone receptors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22

    Topics: Calcitriol; Dinoprostone; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel

1992