Page last updated: 2024-11-08

triiodothyronine and Acute Liver Injury, Drug-Induced

triiodothyronine has been researched along with Acute Liver Injury, Drug-Induced in 41 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"We report a patient with primary hypothyroidism, who developed hepatocellular injury due to levothyroxine, synthetic thyroxine."7.74Liver injury induced by levothyroxine in a patient with primary hypothyroidism. ( Aiso, M; Fukusato, T; Hojo, M; Ishii, T; Kawakami, T; Kawasaki, T; Kuyama, Y; Mikami, M; Morisawa, Y; Negoro, S; Takikawa, H; Tanaka, A; Uegaki, S; Yamamoto, T, 2007)
"Exposure of hyperthyroid rats to halothane results in a centrilobular necrosis of the liver and an 11-fold increase in serum glutamate-pyruvate transaminase (SGPT) levels."7.67Paradoxical effects of perturbation of intracellular levels of glutathione on halothane-induced hepatotoxicity in hyperthyroid rats. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1984)
"A series of experiments were conducted to examine the potential role of phase I metabolism in halothane-induced liver injury in the hyperthyroid rat."7.67Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat. ( Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC, 1988)
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats."7.67Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986)
"Administration of anesthetic doses of halothane to hyperthyroid male rats results in the development of hepatic necrosis."7.66Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1983)
"8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis."7.66Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983)
"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h."7.66Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983)
"Hepatic centrilobular necrosis developed in rats pretreated with triiodothyronine (T3) and then anesthetized with halothane, 1 per cent, for two hours at an ambient oxygen concentration."7.66Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Harbison, RD; Hoyle, P; Phythyon, JM; Wood, AJ; Wood, M, 1980)
"Quercetin is a plant flavonoid and has antioxidative properties."5.56Quercetin alleviates hyperthyroidism-induced liver damage via Nrf2 Signaling pathway. ( Hou, Q; Hu, Z; Ma, W; Tian, Z; Zang, L; Zhao, P, 2020)
"Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia."5.28[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias]. ( Constantin, JM; Maroy, B; Moullot, P, 1989)
"Levothyroxine is a synthetic thyroxine and is the treatment of choice for hypothyroidism."3.91Levothyroxine-induced liver injury followed by complete recovery upon cessation of the drug: a case report. ( Al-Khairalla, MZH; Hlaihel, AF, 2019)
"We report a patient with primary hypothyroidism, who developed hepatocellular injury due to levothyroxine, synthetic thyroxine."3.74Liver injury induced by levothyroxine in a patient with primary hypothyroidism. ( Aiso, M; Fukusato, T; Hojo, M; Ishii, T; Kawakami, T; Kawasaki, T; Kuyama, Y; Mikami, M; Morisawa, Y; Negoro, S; Takikawa, H; Tanaka, A; Uegaki, S; Yamamoto, T, 2007)
"Exposure of hyperthyroid rats to halothane results in a centrilobular necrosis of the liver and an 11-fold increase in serum glutamate-pyruvate transaminase (SGPT) levels."3.67Paradoxical effects of perturbation of intracellular levels of glutathione on halothane-induced hepatotoxicity in hyperthyroid rats. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1984)
"A series of experiments were conducted to examine the potential role of phase I metabolism in halothane-induced liver injury in the hyperthyroid rat."3.67Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat. ( Berman, LM; Harbison, RD; James, RC; Roberts, SM; Smith, AC, 1988)
"1% hexachlorobenzene (HCB) for 55 days on mortality, body weight, urinary porphyrin excretion, serum thyroid hormones and induction of liver microsomal enzymes was studied in female Sprague-Dawley rats."3.67Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria. ( Gorski, JR; Parkinson, A; Rozman, K; Rozman, P, 1986)
"Administration of anesthetic doses of halothane to hyperthyroid male rats results in the development of hepatic necrosis."3.66Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity. ( Berman, ML; Harbison, RD; James, RC; Smith, AC, 1983)
"8% enflurane, or 1% halothane in 21% oxygen (air) for two hours resulted in hepatic centrilobular necrosis."3.66Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Holaday, DA; Kuhnert, L; Phythyon, JM, 1983)
"Factors affecting halothane (H) hepatotoxicity were investigated in two animal models: 1) the phenobarbital-hypoxia model, and 2) the triiodothyronine (T3) model; in the latter we previously have shown that centrilobular necrosis occurs in T3 pretreated rats anesthetized with 1% H, in 21% oxygen for 2 h."3.66Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications. ( Phythyon, JM; Uetrecht, J; Wood, AJ; Wood, M, 1983)
"Hepatic centrilobular necrosis developed in rats pretreated with triiodothyronine (T3) and then anesthetized with halothane, 1 per cent, for two hours at an ambient oxygen concentration."3.66Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats. ( Berman, ML; Harbison, RD; Hoyle, P; Phythyon, JM; Wood, AJ; Wood, M, 1980)
"Quercetin is a plant flavonoid and has antioxidative properties."1.56Quercetin alleviates hyperthyroidism-induced liver damage via Nrf2 Signaling pathway. ( Hou, Q; Hu, Z; Ma, W; Tian, Z; Zang, L; Zhao, P, 2020)
" Therefore, it is necessary to assess the toxic effects of those kind of industrial chemicals during liver development."1.51Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations. ( Faiola, F; Liang, S; Yin, N, 2019)
"Recent work has demonstrated the importance of post-transcriptional gene regulation in toxic responses."1.39Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity. ( Darras, VM; Dudek, KM; Gant, TW; Marczylo, EL; Suter, L, 2013)
" We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts."1.37FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011)
" An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems."1.36Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010)
" It is concluded that hyperthyroidism increases the susceptibility of the liver to the toxic effects of lindane, which seems to be accomplished by potentiation of the hepatic oxidative stress status."1.29Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat. ( Fernández, V; Junqueira, VB; Simon, KA; Smok, G; Troncoso, P; Videla, LA, 1995)
"Plethoryl is a combination of triatricol, cyclovalone and vitamin A normally prescribed in the treatment of hypercholesterolaemia."1.28[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias]. ( Constantin, JM; Maroy, B; Moullot, P, 1989)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199020 (48.78)18.7374
1990's2 (4.88)18.2507
2000's4 (9.76)29.6817
2010's13 (31.71)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Greene, N1
Fisk, L1
Naven, RT1
Note, RR1
Patel, ML1
Pelletier, DJ1
Ekins, S1
Williams, AJ1
Xu, JJ1
Chen, M2
Vijay, V1
Shi, Q2
Liu, Z2
Fang, H2
Tong, W3
Ding, D1
Kelly, R1
Sakatis, MZ1
Reese, MJ1
Harrell, AW1
Taylor, MA1
Baines, IA1
Chen, L1
Bloomer, JC1
Yang, EY1
Ellens, HM1
Ambroso, JL1
Lovatt, CA1
Ayrton, AD1
Clarke, SE1
Aleo, MD1
Luo, Y1
Swiss, R1
Bonin, PD1
Potter, DM1
Will, Y1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Liu, K1
Chen, X1
Ren, Y1
Liu, C1
Zhang, J2
Wang, Z1
Li, Y1
Zhang, Y1
Hlaihel, AF1
Al-Khairalla, MZH1
Zhao, P1
Hu, Z1
Ma, W1
Zang, L1
Tian, Z1
Hou, Q1
Liang, S2
Yin, N1
Faiola, F1
Dudek, KM1
Suter, L1
Darras, VM1
Marczylo, EL1
Gant, TW1
Warner, JV1
Morton, AP1
Hall, AJ1
Henman, MG1
Pool, LF1
Yang, J1
Li, LF1
Xu, Q1
Weng, WW1
Zhu, YJ1
Dong, MJ1
Simon-Giavarotti, KA1
Giavarotti, L1
Gomes, LF1
Lima, AF1
Veridiano, AM1
Garcia, EA1
Mora, OA1
Fernández, V2
Videla, LA2
Junqueira, VB2
Briukhin, GV1
Nikolina, OV1
Barysheva, SV1
Swarup, D1
Naresh, R1
Varshney, VP1
Balagangatharathilagar, M1
Kumar, P1
Nandi, D1
Patra, RC1
Kawakami, T1
Tanaka, A1
Negoro, S1
Morisawa, Y1
Mikami, M1
Hojo, M1
Yamamoto, T1
Uegaki, S1
Aiso, M1
Kawasaki, T1
Ishii, T1
Kuyama, Y1
Fukusato, T1
Takikawa, H1
Danan, G1
Pessayre, D2
Rueff, B1
Benhamou, JP2
Smith, AC4
Berman, ML4
James, RC4
Harbison, RD5
Kuhnert, L1
Phythyon, JM3
Holaday, DA1
Uetrecht, J1
Wood, AJ2
Wood, M2
Iwaoka, T1
Umeda, T1
Nakayama, M1
Shimada, T1
Fujii, Y1
Miura, F1
Sato, T1
Peterson, ME1
Hoyle, P1
Smok, G1
Troncoso, P1
Simon, KA1
Yamagishi, F1
Komoda, T1
Ohnishi, K1
Itoh, S1
Bleich, HL1
Boro, ES1
Maroy, B1
Moullot, P1
Constantin, JM1
Causse, X1
Paliard, P1
Tran-Thi, TA1
Phillips, J1
Falk, H1
Decker, K1
Roberts, SM2
Berman, LM2
Larrey, D1
Fréneaux, E1
Babany, G1
Berson, A1
Amédée-Manesme, O1
Degott, C2
Bettan, L1
Paugam, B1
Gelman, S1
Atttali, P1
Bernuau, J1
Fabre, M1
Ink, O1
Marti, R1
Voiment, YM1
André, JM1
Rozman, K1
Gorski, JR1
Rozman, P1
Parkinson, A1
Ruiz-Torres, A1

Reviews

1 review available for triiodothyronine and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016

Other Studies

40 other studies available for triiodothyronine and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship;

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des

2011
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2014
3,3',5-triiodo-l-thyronine inhibits drug-induced liver injury through activation of PPARα as revealed by network pharmacology and biological experimental verification.
    Toxicology and applied pharmacology, 2022, 08-01, Volume: 448

    Topics: Acetaminophen; Chemical and Drug Induced Liver Injury; Humans; Liver; Liver Failure, Acute; Network

2022
Levothyroxine-induced liver injury followed by complete recovery upon cessation of the drug: a case report.
    Journal of medical case reports, 2019, Oct-18, Volume: 13, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Hormone Replacement Therapy; Humans; Hypothyr

2019
Quercetin alleviates hyperthyroidism-induced liver damage via Nrf2 Signaling pathway.
    BioFactors (Oxford, England), 2020, Volume: 46, Issue:4

    Topics: Animals; Antioxidants; Body Weight; Catalase; Chemical and Drug Induced Liver Injury; Eating; Gene E

2020
Establishment of a human embryonic stem cell-based liver differentiation model for hepatotoxicity evaluations.
    Ecotoxicology and environmental safety, 2019, Jun-15, Volume: 174

    Topics: Animals; Cell Differentiation; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, D

2019
Decreased translation of Dio3 mRNA is associated with drug-induced hepatotoxicity.
    The Biochemical journal, 2013, Jul-01, Volume: 453, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Iodide Peroxidase; Live

2013
Internet slimming, thyrotoxicosis and the liver.
    The Medical journal of Australia, 2014, Apr-21, Volume: 200, Issue:7

    Topics: Adult; Appetite Depressants; Chemical and Drug Induced Liver Injury; China; Cyclobutanes; Drug Combi

2014
Analysis of 90 cases of antithyroid drug-induced severe hepatotoxicity over 13 years in China.
    Thyroid : official journal of the American Thyroid Association, 2015, Volume: 25, Issue:3

    Topics: Adult; Aged; Antithyroid Agents; Chemical and Drug Induced Liver Injury; China; Female; Graves Disea

2015
Enhancement of lindane-induced liver oxidative stress and hepatotoxicity by thyroid hormone is reduced by gadolinium chloride.
    Free radical research, 2002, Volume: 36, Issue:10

    Topics: Animals; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Energy Me

2002
[Morphological and functional characteristics of thyroid gland in the offspring of female rats with experimental chronic liver disease of various etiology].
    Morfologiia (Saint Petersburg, Russia), 2005, Volume: 128, Issue:5

    Topics: Animals; Animals, Newborn; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; C

2005
Changes in plasma hormones profile and liver function in cows naturally exposed to lead and cadmium around different industrial areas.
    Research in veterinary science, 2007, Volume: 82, Issue:1

    Topics: Animals; Cadmium; Cattle; Chemical and Drug Induced Liver Injury; Environmental Exposure; Environmen

2007
Liver injury induced by levothyroxine in a patient with primary hypothyroidism.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:14

    Topics: Chemical and Drug Induced Liver Injury; Humans; Hypothyroidism; Liver Diseases; Male; Middle Aged; T

2007
[Acute hepatitis probably due to Plethoryl].
    Gastroenterologie clinique et biologique, 1984, Volume: 8, Issue:10

    Topics: Adult; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpenes; Drug Combin

1984
Characterization of hyperthyroidism enhancement of halothane-induced hepatotoxicity.
    Biochemical pharmacology, 1983, Dec-01, Volume: 32, Issue:23

    Topics: Alanine Transaminase; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Inj

1983
Paradoxical effects of perturbation of intracellular levels of glutathione on halothane-induced hepatotoxicity in hyperthyroid rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:2 Pt 1

    Topics: Acetylcysteine; Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Glutathione;

1984
Isoflurane and enflurane-induced hepatic necrosis in triiodothyronine-pretreated rats.
    Anesthesiology, 1983, Volume: 58, Issue:1

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Eating; Enflurane; Halothane; Hyperthy

1983
Contrasting effects on halothane hepatotoxicity in the phenobarbital-hypoxia and triiodothyronine model: mechanistic implications.
    Anesthesiology, 1983, Volume: 59, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Fasting; Fluorides; Halothane; Hypoxia; Liver Disea

1983
A case of membranous nephropathy associated with thyroid antigens.
    Japanese journal of medicine, 1982, Volume: 21, Issue:1

    Topics: Antigens; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Humans; Hypothyroidism; I

1982
Propylthiouracil in the treatment of feline hyperthyroidism.
    Journal of the American Veterinary Medical Association, 1981, Sep-01, Volume: 179, Issue:5

    Topics: Administration, Oral; Animals; Cat Diseases; Cats; Chemical and Drug Induced Liver Injury; Hyperthyr

1981
Halothane-induced hepatic necrosis in triiodothyronine-pretreated rats.
    Anesthesiology, 1980, Volume: 52, Issue:6

    Topics: Alanine Transaminase; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cytochrome P-450

1980
Influence of hyperthyroidism on lindane-induced hepatotoxicity in the rat.
    Biochemical pharmacology, 1995, Nov-09, Volume: 50, Issue:10

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury;

1995
Protective effect of dantrolene sodium on carbon tetrachloride induced liver injury in the rat.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 82, Issue:2

    Topics: Alanine Transaminase; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochr

1993
Metabolic and hepatic effects of alcohol.
    The New England journal of medicine, 1977, Mar-17, Volume: 296, Issue:11

    Topics: Acidosis; Alcohol Oxidoreductases; Alcoholism; Amino Acids; Animals; Carbohydrate Metabolism; Chemic

1977
[Probable side effects caused by plethoryl. Common acute hepatitis, anicteric hepatitis, cirrhosis due to hypervitaminosis A, inflammatory arthralgias].
    Presse medicale (Paris, France : 1983), 1989, Mar-18, Volume: 18, Issue:11

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Cyclohexanes;

1989
[Hepatitis with auto-immunization probably caused by Plethoryl].
    Gastroenterologie clinique et biologique, 1989, Volume: 13, Issue:5

    Topics: Adult; Autoantibodies; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpe

1989
Toxicity of D-galactosamine for rat hepatocytes in monolayer culture.
    Experimental and molecular pathology, 1985, Volume: 42, Issue:1

    Topics: Albumins; Animals; Calcium; Calmodulin; Cell Membrane Permeability; Cell Survival; Cells, Cultured;

1985
Comparison of covalent binding from halothane metabolism in hepatic microsomes from phenobarbital-induced and hyperthyroid rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1988, Volume: 18, Issue:8

    Topics: Animals; Chemical and Drug Induced Liver Injury; Glutathione; Halothane; Hyperthyroidism; Lipid Meta

1988
[Hepatitis probably caused by Plethoryl. Apropos of 7 cases].
    Gastroenterologie clinique et biologique, 1988, Volume: 12, Issue:3

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpen

1988
Effects of piperonyl butoxide on halothane hepatotoxicity and metabolism in the hyperthyroid rat.
    Toxicology, 1988, Volume: 50, Issue:1

    Topics: Administration, Inhalation; Animals; Chemical and Drug Induced Liver Injury; Chlorofluorocarbons; Cy

1988
Halothane hepatotoxicity--again?
    Anesthesia and analgesia, 1986, Volume: 65, Issue:8

    Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Guinea Pigs; Halothane; Humans;

1986
[Fatal fulminant hepatitis probably due to Plethoryl].
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpenes; Drug Combin

1986
[Acute hepatitis caused by Plethoryl].
    Gastroenterologie clinique et biologique, 1986, Volume: 10, Issue:12

    Topics: Acute Disease; Chemical and Drug Induced Liver Injury; Cyclohexanes; Cyclohexanones; Diterpenes; Dru

1986
Reduced serum thyroid hormone levels in hexachlorobenzene-induced porphyria.
    Toxicology letters, 1986, Volume: 30, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorobenzenes;

1986
[Dynamics of collagen during hepatic injury by carbon tetrachloride. Problem of the hormonal induction of collagen metabolism].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1971, Volume: 154, Issue:3

    Topics: Animals; Bone and Bones; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced

1971