triiodothyronine has been researched along with Abnormalities, Drug-Induced in 8 studies
Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Several studies have shown that exposure to methimazole (MMI) during the first trimester of pregnancy increases the incidence of specific congenital anomalies that are collectively referred to as MMI embryopathy." | 7.81 | Substituting Potassium Iodide for Methimazole as the Treatment for Graves' Disease During the First Trimester May Reduce the Incidence of Congenital Anomalies: A Retrospective Study at a Single Medical Institution in Japan. ( Ito, K; Iwaku, K; Kameda, T; Kobayashi, S; Kunii, Y; Matsumoto, M; Mukasa, K; Noh, JY; Ohye, H; Sugino, K; Suzuki, M; Suzuki, N; Watanabe, N; Yoshihara, A, 2015) |
| " Several studies have shown that exposure to methimazole (MMI) during the first trimester of pregnancy increases the incidence of specific congenital anomalies that are collectively referred to as MMI embryopathy." | 3.81 | Substituting Potassium Iodide for Methimazole as the Treatment for Graves' Disease During the First Trimester May Reduce the Incidence of Congenital Anomalies: A Retrospective Study at a Single Medical Institution in Japan. ( Ito, K; Iwaku, K; Kameda, T; Kobayashi, S; Kunii, Y; Matsumoto, M; Mukasa, K; Noh, JY; Ohye, H; Sugino, K; Suzuki, M; Suzuki, N; Watanabe, N; Yoshihara, A, 2015) |
| " A host of birth defects, including cleft palate, anasarca, ventricular septal defect, and enlargement of the right atrium, were seen in both rats and mice, primarily in the 10 and 20 mg/kg dosage groups, respectively." | 1.32 | Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations. ( Barbee, BD; Butenhoff, JL; Grey, BE; Hanson, RG; Lau, C; Richards, JH; Rogers, JM; Stevenson, LA; Thibodeaux, JR, 2003) |
| "Although exposure to cyanogenic plants or cyanide during pregnancy has adverse effects, no teratological study with cyanide has been conducted in goats or any other ruminant." | 1.32 | Prenatal toxicity of cyanide in goats--a model for teratological studies in ruminants. ( Górniak, SL; Soto-Blanco, B, 2004) |
| "Nitrofen treatment led to decreased plasma T3 and T4 levels without TSH changes." | 1.30 | Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen. ( Alfonso, LF; Alvarez, FJ; Arnaiz, A; Diez-Pardo, JA; Morreale de Escobar, G; Qi, B; Tovar, JA; Valls-i-Soler, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yoshihara, A | 1 |
| Noh, JY | 1 |
| Watanabe, N | 1 |
| Mukasa, K | 1 |
| Ohye, H | 1 |
| Suzuki, M | 1 |
| Matsumoto, M | 1 |
| Kunii, Y | 1 |
| Suzuki, N | 1 |
| Kameda, T | 1 |
| Iwaku, K | 1 |
| Kobayashi, S | 1 |
| Sugino, K | 1 |
| Ito, K | 1 |
| Thibodeaux, JR | 1 |
| Hanson, RG | 1 |
| Rogers, JM | 1 |
| Grey, BE | 1 |
| Barbee, BD | 1 |
| Richards, JH | 1 |
| Butenhoff, JL | 1 |
| Stevenson, LA | 1 |
| Lau, C | 1 |
| Soto-Blanco, B | 1 |
| Górniak, SL | 1 |
| Manson, JM | 1 |
| Costlow, RD | 1 |
| Hirsekorn, JM | 1 |
| Stiratelli, RG | 1 |
| O'Hara, GP | 1 |
| Black, DL | 1 |
| Kane, WW | 1 |
| Burke, SS | 1 |
| Smith, JM | 1 |
| Hayes, AW | 1 |
| Tovar, JA | 1 |
| Qi, B | 1 |
| Diez-Pardo, JA | 1 |
| Alfonso, LF | 1 |
| Arnaiz, A | 1 |
| Alvarez, FJ | 1 |
| Valls-i-Soler, A | 1 |
| Morreale de Escobar, G | 1 |
| Momotani, N | 1 |
| Hamada, N | 1 |
| Ban, Y | 1 |
| Mimura, T | 1 |
| Nishikawa, Y | 1 |
| Gottesfeld, Z | 1 |
| Silverman, PB | 1 |
1 review available for triiodothyronine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Mechanism of environmental agents by class associated with adverse female reproductive outcome.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Bone and Bones; Female; Gestational Age; He | 1984 |
7 other studies available for triiodothyronine and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Substituting Potassium Iodide for Methimazole as the Treatment for Graves' Disease During the First Trimester May Reduce the Incidence of Congenital Anomalies: A Retrospective Study at a Single Medical Institution in Japan.
Topics: Abnormalities, Drug-Induced; Adult; Antithyroid Agents; Drug Substitution; Female; Graves Disease; H | 2015 |
Exposure to perfluorooctane sulfonate during pregnancy in rat and mouse. I: maternal and prenatal evaluations.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Alkanesulfonic Acids; Animals; Body Weight; Dose- | 2003 |
Prenatal toxicity of cyanide in goats--a model for teratological studies in ruminants.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Goats; Male; Models, Animal; Potassium Cy | 2004 |
The effects on rat pups when nitrofen (4-(2,4-dichlorophenoxy)nitrobenzene) was applied dermally to the dam during organogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetus; Harderian Gland; Herbicides; Kidne | 1983 |
Thyroid hormones in the pathogenesis of lung hypoplasia and immaturity induced in fetal rats by prenatal exposure to nitrofen.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Disease Models, Animal; Female; Herni | 1997 |
[Management of patients with thyrotoxicosis of childbearing age (author's transl)].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Antithyroid Agents; Female; Graves Diseas | 1977 |
Developmental delays associated with prenatal alcohol exposure are reversed by thyroid hormone treatment.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Disease Models, Animal; Embryonic and Fetal | 1990 |