Page last updated: 2024-11-08

triiodothyronine and 2019 Novel Coronavirus Disease

triiodothyronine has been researched along with 2019 Novel Coronavirus Disease in 33 studies

Triiodothyronine: A T3 thyroid hormone normally synthesized and secreted by the thyroid gland in much smaller quantities than thyroxine (T4). Most T3 is derived from peripheral monodeiodination of T4 at the 5' position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3.
3,3',5-triiodo-L-thyronine : An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.

Research Excerpts

ExcerptRelevanceReference
"Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support), ClinicalTrials."2.94Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial. ( Armaganidis, A; Kostopanagiotou, G; Mourouzis, I; Pantos, C; Trikas, A; Tseti, I, 2020)
"Subacute thyroiditis, autoimmune thyroiditis and an atypical form of thyroiditis are complications of COVID-19."2.72Thyroid complications of SARS and coronavirus disease 2019 (COVID-19). ( Somogyi, P; Speer, G, 2021)
"The novel coronavirus disease 2019 (COVID-19) produced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is sweeping the world in a very short time."2.72Potential Interaction Between SARS-CoV-2 and Thyroid: A Review. ( Chen, W; Lei, J; Li, Z; Tian, Y; Wei, T; Zhu, J, 2021)
"Data on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, including overt thyrotoxicosis and suppression of thyroid function."1.62Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients. ( Ahn, J; Lee, JH; Lee, MK; Sohn, SY, 2021)
"We analyzed the clinical relevance of Low T3 syndrome in COVID-19 patients and, in particular, in those with associated hematological malignancies."1.62Gene signature and immune cell profiling by high-dimensional, single-cell analysis in COVID-19 patients, presenting Low T3 syndrome and coexistent hematological malignancies. ( Amodeo, R; Anibaldi, P; Ciliberto, G; D'Ascanio, M; De Dominicis, C; de Latouliere, L; De Vitis, C; Di Napoli, A; Fanciulli, M; Giovagnoli, S; Laghi, A; Mancini, R; Napoli, C; Petrucca, A; Piaggio, G; Ricci, A; Sacconi, A; Salerno, G; Salvati, V; Santino, I; Sciacchitano, S; Simmaco, M; Tafuri, A, 2021)
"Sepsis and septic shock result in impaired microcirculation and red blood cell rheology which lead to tissue hypoxia and multi-organ failure."1.62Acute triiodothyronine treatment and red blood cell sedimentation rate (ESR) in critically ill COVID-19 patients: A novel association? ( Apostolaki, V; Kokkinos, L; Mourouzis, I; Pantos, C; Trikas, A, 2021)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's33 (100.00)2.80

Authors

AuthorsStudies
Ahn, J1
Lee, MK1
Lee, JH1
Sohn, SY1
Ilera, V1
Delfino, LC1
Zunino, A1
Glikman, P1
Drnovsek, M1
Reyes, A1
Dios, A1
Toibaro, J1
Pachioli, V1
Lannes, N1
Guida, A1
Gauna, A1
Lui, DTW4
Hung, IFN4
Lee, CH4
Lee, ACH4
Tam, AR4
Pang, P2
Ho, TY2
Cheung, CYY3
Fong, CHY4
Law, CY4
To, KKW4
Lam, CW4
Chow, WS4
Woo, YC4
Lam, KSL4
Tan, KCB4
Davis, PJ1
Lin, HY1
Hercbergs, A1
Keating, KA1
Mousa, SA1
Sparano, C1
Zago, E1
Morettini, A1
Nozzoli, C1
Yannas, D1
Adornato, V1
Caldini, E1
Vaudo, M1
Maggi, M1
Petrone, L1
Nakamura, S1
Kido, N1
Watanabe, M1
Ohmachi, Y1
Inayama, Y1
Kashitani, Y1
Ishii, K1
Ishida, I1
Goda, N1
Fujita, Y1
Iida, K1
Cristinel Badiu, D1
Popescu, GC1
Zgura, A1
Mercan Stanciu, A1
Dodot, MD1
Mehedintu, C1
Toma, L1
Razvan, S1
Bacinschi, X1
Haineala, B1
Urhan, E1
Karaca, Z1
Kara, CS1
Yuce, ZT1
Unluhizarci, K1
Okoye, C1
Niccolai, F1
Rogani, S1
Lemmi, B1
Peta, U1
Del Vecchio, S1
Morelli, V1
Caraccio, N1
Calsolaro, V1
Monzani, F1
Kwok, STM1
Atalay, A1
Besimoglu, B1
Sinaci, S1
Kaya, E1
Ozkavak, O1
Ocal, FD1
Ozgu-Erdinc, AS1
Sahin, D1
Razu, MH2
Hossain, MI2
Ahmed, ZB2
Bhowmik, M2
Hasan, MKE2
Kibria, MK2
Moni, DA2
Khan, M2
Alphan Uc, Z1
Yagcı, P1
Adibelli, Z1
Duran, C1
Croce, L1
Zampogna, E1
Coperchini, F1
Costa, P1
Pignatti, P1
Visca, D1
Spanevello, A1
Rotondi, M1
Pantos, C3
Tseti, I2
Mourouzis, I3
Brancatella, A1
Ricci, D1
Viola, N1
Sgrò, D1
Santini, F1
Latrofa, F1
Kostopanagiotou, G1
Armaganidis, A1
Trikas, A2
Gao, W1
Guo, W1
Guo, Y1
Shi, M1
Dong, G1
Wang, G1
Ge, Q1
Zhu, J2
Zhou, X1
Khoo, B1
Tan, T1
Clarke, SA1
Mills, EG1
Patel, B1
Modi, M1
Phylactou, M1
Eng, PC1
Thurston, L1
Alexander, EC1
Meeran, K1
Comninos, AN1
Abbara, A1
Dhillo, WS1
Kruger, EC1
Banderker, R1
Erasmus, RT1
Zemlin, AE1
Speer, G1
Somogyi, P1
Chen, W1
Tian, Y1
Li, Z1
Wei, T1
Lei, J1
Campi, I1
Bulgarelli, I1
Dubini, A1
Perego, GB1
Tortorici, E1
Torlasco, C1
Torresani, E1
Rocco, L1
Persani, L1
Fugazzola, L1
Sciacchitano, S1
De Vitis, C1
D'Ascanio, M1
Giovagnoli, S1
De Dominicis, C1
Laghi, A1
Anibaldi, P1
Petrucca, A1
Salerno, G1
Santino, I1
Amodeo, R1
Simmaco, M1
Napoli, C1
Tafuri, A1
Di Napoli, A1
Sacconi, A1
Salvati, V1
Ciliberto, G1
Fanciulli, M1
Piaggio, G1
de Latouliere, L1
Ricci, A1
Mancini, R1
Leung, EKH1
Fröhlich, E1
Wahl, R1
Ashraf, S2
Imran, MA1
Hafsa, HT1
Khalid, S1
Akram, MK1
Ghufran, M1
Cheema, KK1
Ahmad, A1
Izhar, M1
Baldelli, R1
Nicastri, E1
Petrosillo, N1
Marchioni, L1
Gubbiotti, A1
Sperduti, I1
Di Giacinto, P1
Rizza, L1
Rota, F1
Franco, M1
Lania, A1
Aimaretti, G1
Ippolito, G1
Zuppi, P1
Apostolaki, V1
Kokkinos, L1
Assimakopoulos, SF1
Markantes, GK1
Papageorgiou, D1
Mamali, I1
Markou, KB1
Marangos, M1
Michalaki, MA1
Calcaterra, V1
Biganzoli, G1
Dilillo, D1
Mannarino, S1
Fiori, L1
Pelizzo, G1
Zoia, E1
Fabiano, V1
Carlucci, P1
Camporesi, A1
Corti, C1
Mercurio, G1
Izzo, F1
Biganzoli, E1
Zuccotti, G1
Llamas, M1
Garo, ML1
Giovanella, L1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Thyroid Function Tests and the Status of Thyroid Autoantibodies in Hospitalized Covid-19 Patients and Their Relationship With White Blood Cells, Neutrophil / Lymphocyte Ratio, c Reactive Protein, Fibrinogen, Procalcitonin, Ferritin and D-dimer[NCT04659200]20 participants (Actual)Observational2020-09-01Completed
Triiodothyronine for the Treatment of Critically Ill Patients With COVID-19 Infection (Thy-Support)[NCT04348513]Phase 25 participants (Actual)Interventional2020-05-29Terminated (stopped due to Due to specific inclusion criteria no more subjects could be enrolled.)
Hormonal Contributors to Coronavirus SARS-CoV-2 Infection (COV-ENDO)[NCT05749770]220 participants (Anticipated)Observational2020-05-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for triiodothyronine and 2019 Novel Coronavirus Disease

ArticleYear
Thyroid complications of SARS and coronavirus disease 2019 (COVID-19).
    Endocrine journal, 2021, Feb-28, Volume: 68, Issue:2

    Topics: Angiotensin-Converting Enzyme 2; COVID-19; Graves Disease; Humans; Hypothyroidism; Mortality; Progno

2021
Potential Interaction Between SARS-CoV-2 and Thyroid: A Review.
    Endocrinology, 2021, 03-01, Volume: 162, Issue:3

    Topics: Adrenal Cortex Hormones; Comorbidity; COVID-19; COVID-19 Drug Treatment; Female; Heparin, Low-Molecu

2021
Physiological Role and Use of Thyroid Hormone Metabolites - Potential Utility in COVID-19 Patients.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Comorbidity; COVID-19; Diiodothyronines; Humans; Iodide Peroxidase; SARS-CoV-2; Thyroid Diseases; Th

2021
Low free-T3 serum levels and prognosis of COVID-19: systematic review and meta-analysis.
    Clinical chemistry and laboratory medicine, 2021, Nov-25, Volume: 59, Issue:12

    Topics: COVID-19; Humans; Intensive Care Units; Odds Ratio; Prognosis; SARS-CoV-2; Survival Analysis; Triiod

2021

Trials

1 trial available for triiodothyronine and 2019 Novel Coronavirus Disease

ArticleYear
Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial.
    Trials, 2020, Jun-26, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betacoronavirus; Coronavirus Infections; COVID-19; COVID

2020

Other Studies

28 other studies available for triiodothyronine and 2019 Novel Coronavirus Disease

ArticleYear
Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients.
    Endocrinology and metabolism (Seoul, Korea), 2021, Volume: 36, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; COVID-19; Female; Humans; Male; Middle A

2021
Correlation between inflammatory parameters and pituitary-thyroid axis in patients with COVID-19.
    Endocrine, 2021, Volume: 74, Issue:3

    Topics: C-Reactive Protein; COVID-19; Female; Humans; Male; Middle Aged; SARS-CoV-2; Thyroid Gland; Thyroid

2021
The Impact of Interferon Beta-1b Therapy on Thyroid Function and Autoimmunity Among COVID-19 Survivors.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; Antibodies; Autoimmunity; Cohort Studies; COVID-19; COVID-19 Drug Treatment; Female; Follow-U

2021
Possible Contributions of Nongenomic Actions of Thyroid Hormones to the Vasculopathic Complex of COVID-19 Infection.
    Endocrine research, 2022, Volume: 47, Issue:1

    Topics: COVID-19; Humans; Integrin alphaVbeta3; Male; SARS-CoV-2; Thyroid Hormones; Thyroxine; Triiodothyron

2022
Euthyroid sick syndrome as an early surrogate marker of poor outcome in mild SARS-CoV-2 disease.
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; COVID-19; Euthyroid Sick Syndromes; Female; Humans; Male; Middl

2022
Analysis of thyroid function in Japanese patients with coronavirus disease 2019.
    Endocrine journal, 2022, Jun-28, Volume: 69, Issue:6

    Topics: COVID-19; Humans; Japan; Retrospective Studies; SARS-CoV-2; Thyroid Function Tests; Thyroid Gland; T

2022
A Prospective Observational Study of 42 Patients with COVID-19 infection and a History of Hepatitis C Virus Infection and Thyroid Disease with Follow-Up Thyroid Function and Autoantibody Testing.
    Medical science monitor : international medical journal of experimental and clinical research, 2021, Dec-31, Volume: 27

    Topics: Adult; Aged; COVID-19; Female; Follow-Up Studies; Hepacivirus; Hepatitis C; Humans; Hypothyroidism;

2021
The Independent Association of TSH and Free Triiodothyronine Levels With Lymphocyte Counts Among COVID-19 Patients.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Adult; Aged; China; COVID-19; Female; Hospitalization; Humans; Lymphocyte Count; Lymphocytes; Lympho

2021
The potential impact of COVID-19 on thyroid gland volumes among COVID-19 survivors.
    Endocrine, 2022, Volume: 76, Issue:3

    Topics: Adult; COVID-19; Humans; SARS-CoV-2; Survivors; Thyroid Function Tests; Thyroid Gland; Thyrotropin;

2022
Is non-thyroidal illness syndrome (NTIS) a clinical predictor of COVID-19 mortality in critically ill oldest old patients?
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:9

    Topics: Aged, 80 and over; COVID-19; Critical Illness; Euthyroid Sick Syndromes; Humans; Thyrotropin; Triiod

2022
Development of a prediction score (ThyroCOVID) for identifying abnormal thyroid function in COVID-19 patients.
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:11

    Topics: C-Reactive Protein; COVID-19; Female; Humans; Male; Middle Aged; SARS-CoV-2; Thyroid Function Tests;

2022
The impact of covid-19 on thyroid function tests in pregnancy.
    Endocrine, 2023, Volume: 79, Issue:3

    Topics: COVID-19; Female; Humans; Pregnancy; SARS-CoV-2; Thyroid Function Tests; Thyrotropin; Thyroxine; Tri

2023
Study of thyroid function among COVID-19-affected and non-affected people during pre and post-vaccination.
    BMC endocrine disorders, 2022, Dec-09, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Hypothyroidism; Pilot Projects; Retrospective Studies; Thyroid Hormones; Thyrotrop

2022
Study of thyroid function among COVID-19-affected and non-affected people during pre and post-vaccination.
    BMC endocrine disorders, 2022, Dec-09, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Hypothyroidism; Pilot Projects; Retrospective Studies; Thyroid Hormones; Thyrotrop

2022
Study of thyroid function among COVID-19-affected and non-affected people during pre and post-vaccination.
    BMC endocrine disorders, 2022, Dec-09, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Hypothyroidism; Pilot Projects; Retrospective Studies; Thyroid Hormones; Thyrotrop

2022
Study of thyroid function among COVID-19-affected and non-affected people during pre and post-vaccination.
    BMC endocrine disorders, 2022, Dec-09, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Hypothyroidism; Pilot Projects; Retrospective Studies; Thyroid Hormones; Thyrotrop

2022
The Spectrum of Thyroid Function Tests and Autoantibodies During Hospitalization and After Six Months of Discharge in COVID-19 Patients: Does COVID-19 Trigger Autoimmunity?
    Endocrine research, 2023, Jul-03, Volume: 48, Issue:2-3

    Topics: Adult; Aftercare; Autoantibodies; Autoimmunity; COVID-19; Hospitalization; Humans; Hypothyroidism; P

2023
Thyroid hormones modifications among COVID-19 patients undergoing pulmonary rehabilitation.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: COVID-19; Humans; Respiration, Artificial; Thyroid Hormones; Thyroxine; Triiodothyronine

2023
Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial.
    Critical care (London, England), 2020, 05-08, Volume: 24, Issue:1

    Topics: Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Humans; Pandemics; Pneumonia, V

2020
Subacute Thyroiditis After Sars-COV-2 Infection.
    The Journal of clinical endocrinology and metabolism, 2020, 07-01, Volume: 105, Issue:7

    Topics: Adolescent; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID

2020
Thyroid hormone concentrations in severely or critically ill patients with COVID-19.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cause of Death; China; Comorbidity; COVID-19; Critical Illness; Fema

2021
Thyroid Function Before, During, and After COVID-19.
    The Journal of clinical endocrinology and metabolism, 2021, 01-23, Volume: 106, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Comorbidity; COVID-19; Female; Follow-Up Studies; Hu

2021
The impact of COVID-19 on routine patient care from a laboratory perspective.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2020, 11-05, Volume: 110, Issue:12

    Topics: Ambulatory Care; Bilirubin; Blood Chemical Analysis; Blood Protein Electrophoresis; Clinical Laborat

2020
The spectrum of thyroid function tests during hospitalization for SARS COV-2 infection.
    European journal of endocrinology, 2021, Volume: 184, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Autoantibodies; C-Reactive Protein; COVID-19; Female; Humans; Hydroc

2021
Gene signature and immune cell profiling by high-dimensional, single-cell analysis in COVID-19 patients, presenting Low T3 syndrome and coexistent hematological malignancies.
    Journal of translational medicine, 2021, 04-01, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; COVID-19; Euthyroid Sick Syndromes; Female; Hematologic Neoplasms; Humans;

2021
Role of non-thyroidal illness syndrome in predicting adverse outcomes in COVID-19 patients predominantly of mild-to-moderate severity.
    Clinical endocrinology, 2021, Volume: 95, Issue:3

    Topics: Adult; COVID-19; Euthyroid Sick Syndromes; Humans; Middle Aged; Prospective Studies; SARS-CoV-2; Tri

2021
COVID-19: A Potential Trigger for Thyroid Dysfunction.
    The American journal of the medical sciences, 2021, Volume: 362, Issue:3

    Topics: Anti-Inflammatory Agents; C-Reactive Protein; COVID-19; COVID-19 Drug Treatment; Glucocorticoids; Hu

2021
Thyroid dysfunction in COVID-19 patients.
    Journal of endocrinological investigation, 2021, Volume: 44, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; COVID-19; Critical Care; Euthyroid Sick Syndromes; Female; Hospitali

2021
Acute triiodothyronine treatment and red blood cell sedimentation rate (ESR) in critically ill COVID-19 patients: A novel association?
    Clinical hemorheology and microcirculation, 2021, Volume: 79, Issue:3

    Topics: Blood Sedimentation; COVID-19; Critical Illness; Erythrocytes; Humans; SARS-CoV-2; Sepsis; Shock, Se

2021
Low serum TSH in the acute phase of COVID-19 pneumonia: thyrotoxicosis or a face of "non-thyroidal illness syndrome"?
    Clinical chemistry and laboratory medicine, 2021, 10-26, Volume: 59, Issue:11

    Topics: Aged; Biomarkers; Coronavirus Infections; COVID-19; Euthyroid Sick Syndromes; Female; Ferritins; Hum

2021
Non-thyroidal illness syndrome and SARS-CoV-2-associated multisystem inflammatory syndrome in children.
    Journal of endocrinological investigation, 2022, Volume: 45, Issue:1

    Topics: Adolescent; Child; Child, Preschool; COVID-19; Euthyroid Sick Syndromes; Female; Humans; Italy; Male

2022